Clinical trials
Efficacy and Safety clinical trials
Below are recruiting efficacy and safety clinical trials, each written for real people, not researchers. We’re tracking 2,733 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06000592Recruiting
Spinal stimulation to stabilize blood pressure after spinal cord injury
This trial tests whether a non-invasive device that sends gentle electrical pulses to the spinal cord can help people with a recent spinal cord injury keep their blood pressure steady. It's designed for those who experience low blood pressure when sitting or standing, which can cause dizziness or fainting.
New York, New YorkAges 14–100 - NCT06408337RecruitingPhase 1/Phase 2
Biocleft for cleft palate repair in children
This trial tests a new treatment called BIOCLEFT, made from your child's own cheek cells, to help repair a complete cleft palate on one side. It aims to see if the treatment is safe and works better than standard surgery.
Granada, Spain/GranadaAges 10 months–1.2 years - NCT04422366RecruitingPhase 3
9-valent HPV vaccine study for healthy Chinese women
This trial tests a 9-type HPV vaccine to see how well it works, how it helps the body build protection, and whether it’s safe. It’s for healthy Chinese women who have not had HPV vaccination before and meet specific health and timing requirements.
Liuzhou, GuangxiAges 20–45 - NCT06207552RecruitingEarly Phase 1
Gene therapy study for children with Fabry disease
This study tests a new gene therapy for children aged 7 to 17 with Fabry disease. The treatment aims to fix the faulty gene that causes the condition, which may help reduce symptoms and prevent organ damage.
ShanghaiAges 7–18 - NCT07802405RecruitingPhase 1
Testing a new drug alone or with ruxolitinib for myelofibrosis
This trial is testing a new drug called WJ01024, which may help treat myelofibrosis. It can be taken alone or with ruxolitinib, a standard treatment for this condition. The study checks safety and how well it works.
Zhengzhou, HenanAges 3 weeks+ - NCT07807111RecruitingPhase 1/Phase 2
Gene therapy for advanced rod-cone dystrophy
This study tests a new gene therapy for people with advanced rod-cone dystrophy, a genetic condition that causes progressive vision loss. The treatment is given as an injection into the eye, and the study aims to see if it is safe and if it can help improve or preserve vision.
GhentAges 18 years+ - NCT07799116RecruitingPhase 1/Phase 2
Car-t cell therapy for refractory lupus nephritis
This trial tests a new treatment called CD19 CAR-T cell therapy for people with severe lupus nephritis (lupus-related kidney inflammation) that hasn't improved with usual treatments. The therapy uses your own immune cells to target and possibly reset the immune system, which may reduce kidney damage and help control the disease.
Badalona, BarcelonaAges 18–65 - NCT07792239RecruitingPhase 2
Study of budiodarone for atrial fibrillation
This study tests a new medicine, budiodarone, to help control atrial fibrillation (an irregular heartbeat) in people who haven't been helped by other treatments. It may reduce the time spent in AF and improve symptoms.
GdyniaAges 18–80 - NCT07775391RecruitingPhase 1/Phase 2
Stem cell infusion for early menopause
This trial tests whether a single infusion of stem cells made from human umbilical cord tissue can help women with premature ovarian insufficiency (early menopause) by improving ovarian function and reducing menopause symptoms. Participants will continue their usual hormone replacement therapy during the study.
Beijing, Beijing MunicipalityAges 18–40 - NCT07758634RecruitingPhase 1/Phase 2
Study of an experimental treatment for high blood pressure
This trial tests a new treatment called CTX340 for high blood pressure that is hard to control even with multiple medications. The study aims to see if it is safe and effective.
Port Orange, FloridaAges 18–75 - NCT07710690RecruitingPhase 1
Study of NRG-103 injection for recurrent high-grade glioma
This trial tests a new injection called NRG-103 for people whose high-grade glioma (a fast-growing brain tumor) has come back after standard treatments. The goal is to see if it's safe and if it might help shrink the tumor.
ShanghaiAges 18 years+ - NCT07689643RecruitingEarly Phase 1
Radioactive drug plus immunotherapy for FAP-positive lung cancer
This trial tests a new treatment that uses a radioactive medicine called [177Lu]Lu-RTX-2358 combined with immunotherapy (a type of drug that helps your immune system fight cancer). It is for people with advanced non-small cell lung cancer whose tumors have a specific marker called FAP.
Wuhan, HubeiAges 18 years+ - NCT07680764RecruitingPhase 2
Imzokitug plus pumitamig and chemo for first-line advanced lung cancer
This trial tests a new combination of drugs (imzokitug, pumitamig, and platinum-doublet chemotherapy) as a first treatment for advanced or metastatic non-small cell lung cancer that has not spread to the brain. The goal is to see if adding imzokitug makes the standard treatment work better.
Washington D.C., District of ColumbiaAges 18 years+ - NCT06167681RecruitingPhase 1/Phase 2
Cell Therapy NouvNeu001 for Parkinson's Disease
This trial tests a new cell therapy called NouvNeu001 for Parkinson's disease. It involves a one-time brain surgery to deliver the treatment, and researchers will check if it's safe and helps with symptoms.
Beijing, Beijing MunicipalityAges 50–75 - NCT06615206Recruiting
First CRISPR RNA therapy for MECP2 duplication syndrome
This trial tests a new CRISPR therapy that edits RNA to treat a rare genetic condition called MECP2 duplication syndrome (MDS). It is for boys aged 2 to 18 who have stable seizures and no other major health problems, with the goal of improving symptoms and safety.
Beijing, Beijing MunicipalityAges 2–18 - NCT07604974RecruitingPhase 2
Safety and effectiveness of ION775 for very high triglycerides
This trial tests a new medicine called ION775 to help lower very high triglyceride levels in the blood. Triglycerides are a type of fat, and having too much can increase heart disease risk. The study will check if ION775 is safe and actually works when added to your regular cholesterol medications.
Lincoln, CaliforniaAges 18 years+ - NCT06290557RecruitingPhase 1
Testing safety of a nose spray for staph bacteria
This trial tests a new nose spray called HY-133 to see if it's safe and can clear a common type of staph bacteria from the nose. It is for people who have this bacteria but not the antibiotic-resistant kind.
TübingenAges 18 years+ - NCT07563699RecruitingPhase 1/Phase 2
Long-acting semaglutide injection for type 2 diabetes
This study tests a new long-acting form of semaglutide (a diabetes medication you may already take weekly) given as a depot injection. Researchers want to see if this new form is safe and works better for managing type 2 diabetes.
Tel AvivAges 18–64 - NCT05315167RecruitingPhase 1/Phase 2
Study drug PRJ1-3024 for advanced solid tumors
This trial tests how safe PRJ1-3024 is and how the body handles it, and it also looks for early signs that it can shrink advanced solid tumors. It may help people whose cancer can’t be treated with standard options.
Zhengzhou, HenanAges 18 years+ - NCT07557589Recruiting
Radiofrequency Treatment for Pilonidal Disease Safety and Effectiveness
This study tests a radiofrequency (heat-based) treatment to safely and effectively treat pilonidal sinus disease—a condition where an infected cavity forms near the tailbone. Researchers will check if this non-surgical approach reduces infection, works well, and keeps patients satisfied over 6 months.
DaxAges 18 years+ - NCT07558538RecruitingEarly Phase 1
Inhaled Growth Factor Treatment for Severe Lung Failure
This early-stage trial tests whether an inhaled medication called recombinant human keratinocyte growth factor-2 (rh-KGF-2) can help patients with acute respiratory distress syndrome (ARDS)—a serious condition where the lungs cannot deliver enough oxygen to the blood. The drug is designed to help repair lung tissue damage.
Shanghai, Shanghai MunicipalityAges 18–80 - NCT07559175RecruitingPhase 2
A new enzyme treatment for pancreatic insufficiency
This study tests a new pancreatic enzyme medicine (called NHS7108) for people with exocrine pancreatic insufficiency (EPI). EPI means your pancreas doesn't make enough enzymes to break down food properly. The study aims to see if this new medicine is safe and works well to help your body absorb nutrients.
Scottsdale, ArizonaAges 18–85 - NCT07549698RecruitingPhase 1/Phase 2
CRISPR Gene Therapy for Immune Blood Disorders
This trial tests CTX112, a new CRISPR gene therapy that modifies your immune cells to treat severe immune thrombocytopenic purpura (ITP) or warm autoimmune hemolytic anemia (WAIHA) that hasn't responded to standard treatments. The goal is to see if it's safe and can help your body stop attacking its own blood cells.
Rochester, MinnesotaAges 18 years+ - NCT07542379RecruitingEarly Phase 1
A radioactive treatment for advanced prostate cancer
This early-stage trial tests a new radioactive drug (177Lu-FC516) designed to target and treat prostate cancer that has spread and is no longer responding to standard treatments. The goal is to evaluate whether it is safe and effective.
Wuxi, JiangsuAges 18 years+
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Common questions
- Are there clinical trials for efficacy and safety?
- Yes. Clin2 currently lists 2,733 recruiting efficacy and safety studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a efficacy and safety trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a efficacy and safety trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.