Clinical trials
Efficacy and Safety clinical trials
Below are recruiting efficacy and safety clinical trials, each written for real people, not researchers. We’re tracking 2,799 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07203638Enrolling by invitation
Antibiotics to prevent pneumonia in ventilated patients
This trial tests whether giving preventive antibiotics to adults on breathing machines lowers the risk of developing pneumonia during ventilation. It is a double-blind study, meaning neither you nor your doctor will know if you receive the antibiotic or a placebo.
Banhā, Al-QalyubiaAges 18–70 - NCT07181135Enrolling by invitationPhase 3
Finerenone for kidney disease without certain blood pressure drugs
This trial tests if finerenone can protect kidneys in people with chronic kidney disease who are not taking common blood pressure medications called ACE inhibitors, ARBs, or renin inhibitors. It may help slow kidney damage.
BarcelonaAges 18 years+ - NCT07158307Enrolling by invitation
Studying a new balloon treatment for small heart arteries
This trial tests a special balloon coated with medicine to treat blocked small arteries in the heart. It may help people who have new blockages and are getting a procedure to open those arteries.
UlsanAges 19 years+ - NCT07154784Enrolling by invitationPhase 2/Phase 3
Fecal transplant for long-term ulcerative colitis treatment
This trial tests whether fecal microbiota transplantation (FMT) can safely and effectively treat mild to moderate ulcerative colitis over the long term. FMT involves transferring stool from a healthy donor to restore a healthy balance of gut bacteria.
Seoul, Dongjak-guAges 10–80 - NCT07153003Enrolling by invitationPhase 4
Tramadol and oxycodone vs oxycodone alone for joint pain
This trial tests if taking two pain relievers (tramadol and oxycodone) together works better than oxycodone alone to control pain after knee or hip replacement surgery. It aims to find a more effective way to manage pain with fewer side effects.
Rochester, MinnesotaAges 18 years+ - NCT07132255Enrolling by invitation
Study of remote robot-assisted heart stent placement
This trial tests whether a doctor can use a robot to place a heart stent while being in a different location. It is designed for people who need a stent to open a blocked heart artery.
Jimsar, Xinjiang Uygur Autonomous RegionAges 18–80 - NCT07117240Enrolling by invitationPhase 4
GLP-1 drugs for steroid-induced diabetes
This trial tests whether a GLP-1 receptor agonist (a type of diabetes medication) can safely and effectively treat high blood sugar caused by long-term steroid use. It may help people with type 2 diabetes or steroid-induced diabetes who take oral steroids for conditions like asthma, arthritis, or kidney disease.
Warsaw, WarsawAges 18 years+ - NCT07088081Enrolling by invitation
Immunotherapy drugs for advanced liver cancer
This trial tests two types of immunotherapy (atezolizumab with bevacizumab or durvalumab with tremelimumab) for people with advanced liver cancer that hasn't been treated with systemic therapy before. It aims to see if these treatments are safe and effective.
Cairo, AbbasyaAges 18 years+ - NCT07086313RecruitingPhase 2/Phase 3
Testing a new ADHD drug for children
This trial tests an experimental drug (EB-1020) for children with ADHD. It aims to see if the drug is safe and effective in reducing ADHD symptoms.
SapporoAges 6–17 - NCT07077811Enrolling by invitation
Pulsed field ablation for heart failure with preserved pumping strength
This trial tests a new procedure called pulsed field ablation for people who have both persistent atrial fibrillation and a type of heart failure (HFpEF). It aims to see if this ablation safely helps control the heart rhythm.
Nantong, JiangsuAges 18–80 - NCT07064525Enrolling by invitationPhase 2
Testing a new drug for high blood pressure
This trial tests a new medicine called SPC1001 Low to see if it can safely lower blood pressure in people with essential hypertension (high blood pressure with no known cause). If you are between 19 and 75 years old and have mild to moderate high blood pressure, this study might be an option.
SeoulAges 19–75 - NCT07050134Enrolling by invitation
Study of DR10624 for high triglycerides and carotid artery plaque
This trial tests a new drug, DR10624, to see if it can lower high triglycerides and reduce plaque in the carotid artery (the main artery in your neck). It may help people with both conditions who are also overweight.
Hefei, AnhuiAges 18–65 - NCT07045493Enrolling by invitationPhase 2
Combination therapy for soil-transmitted worms in children aged 2-5
This trial tests whether a combination of medicines works better than a single medicine to treat common intestinal worms (like hookworm and roundworm) in young children in Bangladesh. It is for children who are either stunted (shorter than average for their age) or healthy, and who have a confirmed worm infection.
DhakaAges 2–5 - NCT07003685Enrolling by invitation
Glaucoma drainage device for hard-to-treat glaucoma
This study tests a posterior chamber drainage device for people with glaucoma that is not controlled by eye drops, especially those who have already had cataract surgery. It aims to help lower eye pressure safely and prevent further vision loss.
Ho Chi Minh City, Ho Chi MinhAges 18 years+ - NCT06938217Enrolling by invitation
Low-flow ECMO for adults with severe breathing failure
This study tests whether a gentler, low-blood-flow version of ECMO (a machine that helps oxygenate blood outside the body) is safe and effective for adults with very severe breathing failure. It is for patients who are already on a breathing machine and have very low oxygen levels despite that support.
San Antonio, TexasAges 18–65 - NCT06933992Enrolling by invitation
Chocolate balloon for blocked leg arteries
This trial tests a special balloon called the Chocolate Balloon Catheter to open blocked leg arteries. It may help people with peripheral artery disease avoid more invasive surgery.
HangzhouAges 18–80 - NCT06931483Enrolling by invitation
Brain stimulation for Parkinson's motor symptoms
This trial uses a new type of non-invasive brain stimulation to target a deep brain area that controls movement. It aims to improve motor symptoms like stiffness and slowness in people with Parkinson's disease, without needing surgery.
Hefei, AnhuiAges 50–80 - NCT06931080RecruitingPhase 2/Phase 3
Study of EB-1020 for adults with ADHD
This trial tests a new medication called EB-1020 for adults with ADHD. It aims to see if the drug is safe and effective in improving ADHD symptoms. You may be able to join if you have a clear ADHD diagnosis and your symptoms are moderate to severe.
TokyoAges 18–55 - NCT06888661Enrolling by invitationEarly Phase 1
Testing EXG001-307 for spinal muscular atrophy in infants
This trial tests a new medicine called EXG001-307 for babies with spinal muscular atrophy (SMA) types 1 and 2. The goal is to see if it is safe and helps with muscle strength and breathing.
Shanghai, Shanghai MunicipalityAges 1 day–2 years - NCT06883136Enrolling by invitation
Sintilimab plus chemo for elderly advanced lung cancer
This trial tests a combination of the immunotherapy drug sintilimab plus standard chemotherapy (platinum-based doublet) as the first treatment for older adults (60–80) with advanced non-small cell lung cancer that does not have certain gene mutations. The goal is to see if this approach works better than chemotherapy alone.
Jinan, ShandongAges 60–80 - NCT06880250Enrolling by invitation
Enzyme therapy study for Fabry disease patients
This trial tests if enzyme replacement therapy works well and is safe for Fabry disease. It is for people who are already prescribed this treatment.
AstrakhanAges 8–65 - NCT06880042Enrolling by invitationEarly Phase 1
Narrowband UVB light therapy with tacrolimus or calcipotriol for vitiligo
This study compares two treatments for vitiligo: narrowband UVB light therapy combined with either tacrolimus ointment or calcipotriol ointment. It aims to see which combination works better and is safer for people with stable, limited vitiligo.
Lahore, Punjab ProvinceAges 15–70 - NCT06859697Enrolling by invitation
Herbal medicine for obesity with spine or joint pain
This trial tests whether herbal medicine can safely help with pain and weight loss in people who have both obesity (BMI 25 or higher) and back or joint pain. It aims to see if the treatment works and is safe.
Seoul, Gangnam-GuAges 19–69 - NCT06844240Enrolling by invitation
Testing the safety and effectiveness of the XEN63 gel implant for glaucoma
This study tests a new gel implant (XEN63) to lower eye pressure in adults with open-angle glaucoma. It may be an option if your eye pressure remains high despite using eye drops, or if you can't tolerate the drops.
Acquaviva delle Fonti, ItalyAges 18 years+
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Common questions
- Are there clinical trials for efficacy and safety?
- Yes. Clin2 currently lists 2,799 recruiting efficacy and safety studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a efficacy and safety trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a efficacy and safety trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.