Clinical trials
Efficacy and Safety clinical trials
Below are recruiting efficacy and safety clinical trials, each written for real people, not researchers. We’re tracking 2,733 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06647550RecruitingPhase 2
Testing a new pill for type 2 diabetes not well controlled by diet and exercise
This trial tests a new medication, HD-6277, to see if it can help lower blood sugar in adults with type 2 diabetes that isn't well managed by diet and exercise alone.
SeoulAges 19–75 - NCT07565103RecruitingPhase 1/Phase 2
Testing SUM-191 eye drops for bacterial pink eye
This trial tests a new eye medication called SUM-191 for treating bacterial conjunctivitis (a bacterial infection that causes pink eye). The study has three parts: first testing safety in healthy people, then in people with the infection itself.
Austin, TexasAges 18 years+ - NCT07565428RecruitingPhase 3
Study of roluperidone for negative symptoms of schizophrenia
This trial tests a new medicine called roluperidone for people with schizophrenia who have ongoing negative symptoms (like low motivation or social withdrawal) but stable positive symptoms (like hallucinations). It aims to see if the drug helps with these symptoms and if it can reduce the chance of relapse compared to other medications.
Bellflower, CaliforniaAges 18–55 - NCT07562022RecruitingPhase 3
SCTB35 Plus Lenalidomide for Resistant Follicular Lymphoma
This trial tests a new drug called SCTB35 combined with lenalidomide (a known cancer drug) in people whose follicular lymphoma (a type of blood cancer) has stopped responding to or come back after previous treatments. The combination may help shrink tumors and improve survival.
Beijing, Beijing MunicipalityAges 18–80 - NCT07563881RecruitingPhase 3
Testing RAP-219 for Focal Seizure Control in Adults
This study tests whether a new medication called RAP-219 can help adults with focal seizures (seizures that start in one area of the brain) control their seizures better. You would take this medication alongside your current seizure drugs for about 12 weeks.
Palmdale, CaliforniaAges 18–75 - NCT07564141RecruitingPhase 3
New Drug for Recurrent Ovarian Cancer After Chemotherapy
This study tests a new medicine called Rina-S (with or without a blood vessel-blocking drug) compared to standard chemotherapy options for ovarian cancer that has come back after initial treatment. The goal is to see if Rina-S works better and is safer than current standard care.
Duarte, CaliforniaAges 18 years+ - NCT07565285RecruitingPhase 2
Combination Treatment for Operable Stage III Skin Melanoma
This study tests whether combining a new drug called PRTX007-003 with pembrolizumab (an immunotherapy) can help prevent melanoma from returning after surgery. You would receive both treatments after your tumor is surgically removed.
Waratah, New South WalesAges 18 years+ - NCT05190991RecruitingPhase 2
RPH-104 to prevent repeat fevers in colchicine-resistant FMF
This Phase 2 study tests whether RPH-104 can help prevent recurrent fever attacks in adults with Familial Mediterranean Fever (FMF) who cannot tolerate colchicine or whose disease does not respond to it. Participants may receive the medicine at the clinic or learn to give it as a self-injection, depending on what fits your situation.
YerevanAges 18–80 - NCT07559695Recruiting
Menin inhibitor maintenance therapy after stem cell transplant
This study tracks how well a newer drug class (menin inhibitors) works to prevent acute leukemia from coming back after a stem cell transplant. You would be observed for safety and effectiveness if you're already taking one of these drugs.
Suzhou, JiangsuAges 15 years+ - NCT07564531Recruiting
Safe sedation for heart catheterization in children
This study tests whether a combination of two sedative medications (dexmedetomidine and ketamine) works safely and effectively to keep children calm and still during heart catheterization—a procedure where a thin tube is guided through blood vessels to the heart for diagnosis or treatment.
HanoiAges Up to 18 years - NCT07562282Recruiting
Medication combinations for kidney stone stent discomfort
This trial tests two different doses of medications (tamsulosin and tadalafil) to help with pain and discomfort from a plastic tube (called a DJ stent) placed in your kidney after stone removal surgery. The goal is to find which dose combination works best and is safest.
Cairo, AbbasiaAges 18–71 - NCT07568184Recruiting
New Exosome Treatment for Sudden Hearing Loss
This trial tests a new way to deliver anti-inflammatory medicine directly into the ear using tiny particle carriers called exosomes. It's designed for people who lost hearing suddenly without a clear cause and didn't improve with standard steroid pills.
Kafr ash Shaykh, EgyptAges 18–65 - NCT06727721RecruitingPhase 2
Stem cell therapy for hard-to-treat type 2 diabetes
This trial tests a new stem cell treatment for people with type 2 diabetes that is difficult to control with standard medications. The treatment uses a special kind of stem cell to try to improve blood sugar levels.
ShanghaiAges 18–70 - NCT06734637Recruiting
Peginterferon for essential thrombocythemia and polycythemia vera
This trial tests a medicine called peginterferon for people with two blood disorders: essential thrombocythemia (too many platelets) and polycythemia vera (too many red blood cells). The goal is to see if peginterferon can help control these conditions and is safe.
Wuhan, HubeiAges 18 years+ - NCT06734221Recruiting
Testing a paclitaxel-coated balloon for leg artery disease
This trial tests a special balloon coated with a drug (paclitaxel) to open blocked leg arteries, aiming to improve blood flow and reduce symptoms like leg pain when walking. It is for people with moderate to severe leg artery disease who have not had prior stents or bypass in the treated area.
Chrzanów, MalopolskaAges 18 years+ - NCT06558253RecruitingPhase 1
Coenzyme I for blood recovery after cord blood transplant
This trial tests whether a drug called Coenzyme I (given by injection) can help your blood cells recover faster after a cord blood transplant for blood cancer. It is for people who are getting this type of transplant for the first time and are in fairly good health otherwise.
Hefei, AnhuiAges 18–60 - NCT06362967RecruitingPhase 2
Lowering high antibodies before stem cell transplant
This trial tests a special treatment to lower high levels of anti-HLA antibodies before a stem cell transplant. The goal is to help the transplant succeed and reduce the risk of rejection.
Hefei, AnhuiAges 14–60 - NCT07559370RecruitingPhase 2
Imatinib Plus Artemether-Lumefantrine for Uncomplicated Malaria
This trial tests whether adding a cancer drug called imatinib to standard malaria treatment works better and is safe. Researchers will enroll adults and children with uncomplicated malaria caused by P. falciparum parasites and monitor them in the hospital for 2–3 days.
KisumuAges 1–55 - NCT07552012RecruitingPhase 2
FXS5626 for Non-Infectious Eye Inflammation
This trial tests a new drug called FXS5626 to treat non-infectious uveitis—inflammation inside the eye that doesn't come from infection. The study looks at whether this drug can reduce eye inflammation and improve vision in people whose condition isn't controlled with steroid eye drops and oral steroids alone.
Chongqing, Chongqing MunicipalityAges 18–70 - NCT07552077RecruitingPhase 2
Sirolimus Gel for Angiokeratoma Treatment
This trial tests a topical gel (a cream you apply to skin) containing sirolimus to treat angiokeratomas, which are small growths on the skin. The goal is to see if this treatment is safe and effective.
Sherman Oaks, CaliforniaAges 6 years+ - NCT07551492RecruitingPhase 3
New medicine for people with heart and blood vessel disease
This study tests an investigational medicine called HRS9531 for people with atherosclerotic cardiovascular disease (a buildup of plaque in the arteries that can lead to heart attacks and strokes). The trial aims to see if the medicine helps reduce risks in this condition.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07552389RecruitingPhase 3
Blood Pressure and Diabetes Combination Drug Trial
This study tests whether taking two separate blood pressure medications work as well as taking them combined in one pill for people with high blood pressure and type 2 diabetes. The goal is to find the best, safest way to treat both conditions together.
SeoulAges 19 years+ - NCT05184335RecruitingPhase 3
Brilaroxazine for adults with schizophrenia
This study tests whether brilaroxazine works and is safe for people with schizophrenia. It mainly aims to help people whose symptoms are still present despite prior treatment, while excluding those with certain other diagnoses or substance/drug issues.
Phoenix, ArizonaAges 18–65 - NCT07549100Recruiting
Tislelizumab plus chemotherapy for advanced esophageal cancer
This trial tests whether combining tislelizumab (an immunotherapy drug) with chemotherapy can shrink advanced esophageal cancer before surgery. The goal is to help patients whose tumors are too large or invasive to operate on initially.
Jinan, ShandongAges 18–75
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Common questions
- Are there clinical trials for efficacy and safety?
- Yes. Clin2 currently lists 2,733 recruiting efficacy and safety studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a efficacy and safety trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a efficacy and safety trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.