Clinical trials
Efficacy and Safety clinical trials
Below are recruiting efficacy and safety clinical trials, each written for real people, not researchers. We’re tracking 2,734 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07463521RecruitingPhase 3
Study of rozanolixizumab for ocular myasthenia gravis
This study tests an investigational medication called rozanolixizumab for people who have ocular myasthenia gravis (MG), where weakness is only in the eye muscles. The medicine is given as an injection under the skin and may help improve symptoms like drooping eyelids or double vision.
Scottsdale, ArizonaAges 18 years+ - NCT07469800RecruitingPhase 3
IBI362 for high blood pressure in overweight adults
This study tests an injectable medicine (IBI362) to see if it helps lower blood pressure in people who are overweight or have obesity. You may be eligible if you have high blood pressure but are not currently taking medication for it, and you do not have diabetes or major heart problems.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT07464912RecruitingPhase 3
Testing TDI01 for idiopathic pulmonary fibrosis
This trial tests a new drug called TDI01 to see if it helps people with idiopathic pulmonary fibrosis (IPF), a lung disease that causes scarring. You may qualify if you have a confirmed IPF diagnosis and your lung function is stable enough.
Beijing, Beijing MunicipalityAges 40–80 - NCT07463183RecruitingPhase 2
Study of MK-8690 for moderate to severe ulcerative colitis
This trial tests an investigational drug called MK-8690 for people with moderate to severe ulcerative colitis (UC) who haven't responded well to other treatments or can't tolerate them. The study aims to see if the drug can help control UC symptoms safely.
Anaheim, CaliforniaAges 18–75 - NCT07471789RecruitingPhase 1/Phase 2
CART84 therapy for AML and T-ALL leukemia
This trial tests a new treatment called CART84 (GYA01) for patients with acute myeloid leukemia (AML) or T-cell acute lymphoblastic leukemia (T-ALL) that has come back or not responded to standard treatments. CART84 uses specially engineered immune cells to target and destroy leukemia cells that have a protein called CD84 on their surface.
Barcelona, BarcelonaAges 18 years+ - NCT07470762RecruitingPhase 1/Phase 2
Study of HS-10542 for paroxysmal nocturnal hemoglobinuria (PNH)
This trial tests a new drug, HS-10542, for people with PNH who are already on a C5 inhibitor like eculizumab or covalizumab but still have low hemoglobin or need transfusions. It aims to see if this additional treatment can improve blood counts and reduce transfusion needs.
Hangzhou, ZhejiangAges 18–75 - NCT06647888Recruiting
Study of Enavogliflozin for Type 2 Diabetes with High Blood Pressure or High Cholesterol
This study looks at how well a medication called Enavogliflozin works for people with type 2 diabetes who also have high blood pressure or high cholesterol. It aims to see if the drug is safe and effective when taken as part of routine care.
SeoulAges 19 years+ - NCT06788470RecruitingPhase 1/Phase 2
Stem cell therapy for severe lung disease in premature babies
This trial tests whether umbilical cord stem cells can help premature babies with severe bronchopulmonary dysplasia (a chronic lung disease) who still need a breathing tube after standard hormone treatment. The goal is to see if it is safe and improves their lung condition.
Hangzhou, ZhejiangAges 8 months+ - NCT06788353Recruiting
Liver cancer treatment study for patients not eligible for surgery
This trial is collecting information on how well a treatment (likely TACE, a procedure to block the tumor's blood supply) works for people with liver cancer that cannot be removed by surgery. It aims to see how safe and effective it is for patients who haven't had treatment before or who have a first recurrence.
Guangzhou, GuangdongAges 18–75 - NCT07469683RecruitingPhase 2
Combination therapy for advanced kidney cancer after first-line treatment
This trial tests a combination of two drugs (SLC-3010 and axitinib) versus axitinib alone for people with advanced clear cell kidney cancer that has progressed after initial treatment. It aims to see if the combination is safer and more effective.
SeoulAges 19 years+ - NCT07466719Recruiting
Comparing two ways to give blood transfusions during c-section for heavy bleeding
This trial tests if using a manual syringe or an automatic pressure bag is better and safer for giving blood transfusions to women who have major bleeding during a cesarean section. It aims to find which method works faster and with fewer complications.
AswānAges 18–45 - NCT07463599RecruitingPhase 1/Phase 2
Tegavivint for advanced colorectal cancer after other treatments
This early-phase trial tests an experimental drug called tegavivint for people with advanced colorectal cancer who have already tried several standard treatments. It aims to see if the drug can shrink or slow the growth of tumors.
Scottsdale, ArizonaAges 18 years+ - NCT07464366RecruitingPhase 2
MRG003 with or without putrelimab for salivary gland cancer
This trial tests a new drug combination (MRG003 with or without putrelimab) for people with advanced salivary gland cancer that has EGFR protein. It aims to see if the treatment is safe and helps shrink tumors.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT05504278RecruitingPhase 1
Testing IBI351 with chemotherapy for KRAS G12C lung cancer
This Phase 1 study tests whether IBI351, a targeted medicine, can be safely given with standard chemotherapy to treat advanced lung cancer that has a KRAS G12C mutation. It’s mainly looking at safety and early signs of effectiveness, and may offer a new option if your cancer matches these features.
Jilin City, ChangchunAges 18–75 - NCT07455383RecruitingPhase 3
Testing ALKS 2680 for adults with narcolepsy type 1
This study tests a new medication, ALKS 2680, to see if it helps reduce daytime sleepiness and other symptoms in adults with narcolepsy type 1. It may offer a new treatment option for people with this condition.
Cullman, AlabamaAges 18–70 - NCT07456826Enrolling by invitationPhase 4
Comparing two eye numbing gels for shots
This trial tests a new eye-numbing gel against the standard numbing method to see which works better for patients getting regular anti-VEGF injections in the eye.
Tyler, TexasAges 18 years+ - NCT07456696RecruitingPhase 3
TSND-201 for PTSD treatment study
This trial tests if an investigational drug called TSND-201 can help treat PTSD. It is for people who have tried at least one other PTSD treatment before.
Phoenix, ArizonaAges 18 years+ - NCT07453888RecruitingPhase 3
Nose spray for sudden vision loss from optic nerve damage
This trial tests a nose spray medication (cenegermin) for people who recently lost vision due to a specific type of optic nerve damage (NAION). The goal is to see if it can help restore sight when started within two weeks of vision loss.
Los Angeles, CaliforniaAges 50–80 - NCT07459751RecruitingPhase 2/Phase 3
A study of HLX43 alone or with HLX07 vs docetaxel for advanced squamous lung cancer
This trial tests a new drug called HLX43, given alone or with HLX07, against the standard chemo docetaxel for people with a type of advanced lung cancer called squamous non-small cell lung cancer. It's for patients who have already tried and not responded to platinum chemo and immunotherapy.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07456033RecruitingPhase 3
Depemokimab for adults and teens with type 2 asthma
This study tests a new medicine called depemokimab, given as an injection, to see if it can reduce asthma attacks in people with a specific type of asthma (type 2 high). If you have had asthma for several years and have had recent attacks despite using regular inhalers, this trial might be an option for you.
Little Rock, ArkansasAges 12 years+ - NCT06374667Recruiting
Skull bone injection vs. IV for large stroke
This trial tests a new way to give medicine for a large stroke on one side of the brain. The medicine is injected into the skull bone instead of through a vein, and researchers want to see if it works better and is safe.
Wuhu, AnhuiAges 18–80 - NCT07458256Recruiting
Liposomal bupivacaine for pain after laparoscopic surgery
This trial tests a long-acting painkiller injected during surgery to see if it reduces pain after keyhole (laparoscopic) procedures like gallbladder removal, hernia repair, or appendix removal. It may help you need fewer opioids and recover more comfortably.
Beijing, Beijing MunicipalityAges 18–64 - NCT07458282Recruiting
Testing a long-lasting numbing medicine for pain after laparoscopic surgery
This trial is testing if a special numbing medicine called liposomal bupivacaine, given as a nerve block during surgery, can help reduce pain after laparoscopic procedures like gallbladder removal or hernia repair. It might help you feel better with less need for strong painkillers.
Beijing, Beijing MunicipalityAges 18–64 - NCT07455188Recruiting
Switching targeted therapies for advanced HER2-positive breast cancer
This trial tests whether switching between two targeted therapy combinations can help women with HER2-positive advanced breast cancer that has progressed after previous treatments. It aims to find a new effective option for people who have already tried one or two lines of therapy.
Zhejiang, HangzhouAges 18 years+
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Common questions
- Are there clinical trials for efficacy and safety?
- Yes. Clin2 currently lists 2,734 recruiting efficacy and safety studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a efficacy and safety trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a efficacy and safety trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.