Clinical trials
Epilepsy clinical trials
Below are recruiting epilepsy clinical trials, each written for real people, not researchers. We’re tracking 339 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07075380Recruiting
National survey on physical activity in adults with epilepsy
This survey study asks adults with epilepsy about their physical and sports activity. Your answers will help researchers understand how exercise affects people with epilepsy.
Tain-l'HermitageAges Any age - NCT07087821Recruiting
Epilepsy self-management study for depression
This study tests two programs (UPLIFT and PACES) that help people with epilepsy manage depressive symptoms. If you have epilepsy and mild-to-moderate depression, you may be able to join.
Brooklyn, New YorkAges 18 years+ - NCT07095933RecruitingEarly Phase 1
Everolimus for hard-to-control focal epilepsy
This study tests whether the medicine everolimus (taken as a pill) can safely reduce seizures in adults with focal epilepsy that hasn't been controlled by other treatments. You would continue your current seizure medicines and add everolimus.
Beijing, Beijing MunicipalityAges 18–60 - NCT07116421RecruitingEarly Phase 1
Rose smell and seizure-related breathing pauses study
This study tests whether smelling rose oil can reduce or prevent breathing pauses that sometimes happen during seizures. It is for epilepsy patients staying in the hospital for EEG monitoring.
Nashville, TennesseeAges 18 years+ - NCT07145489Recruiting
Infrared light therapy for seizures
This trial tests whether shining a special infrared light on the scalp can reduce seizures in adults with epilepsy that is not controlled by standard medications. You would receive the light treatments and keep a diary of your seizures.
Boston, MassachusettsAges 18 years+ - NCT07193277RecruitingPhase 4
Butylphthalide for thinking problems in older adults with epilepsy
This study tests whether a medicine called butylphthalide can help improve memory and thinking in older adults with focal epilepsy who already have mild cognitive issues. It aims to find a new way to support brain health in people with epilepsy.
Wenzhou, ZhejiangAges 60–85 - NCT07202494Recruiting
Brain aging and resilience MRI study
This study uses powerful MRI scans to understand how the brain ages and why some people stay healthy while others develop neurological diseases like multiple sclerosis or Alzheimer's. It compares healthy volunteers to people with certain conditions, and all participants get a detailed brain MRI.
MarseilleAges 18–90 - NCT07238868RecruitingPhase 2
Long-term safety study of CB03-154 for epilepsy
This study is a long-term follow-up for people with epilepsy who already completed a previous trial of the drug CB03-154. It checks if the drug remains safe and effective over more time.
Melbourne, VictoriaAges 18–70 - NCT07244328RecruitingEarly Phase 1
UX-GIP001 cell therapy for drug-resistant temporal lobe epilepsy
This trial tests a new cell therapy, UX-GIP001, for people whose seizures start in one small area of the brain (the mesial temporal lobe) and are not controlled by at least two seizure medications. The goal is to see if this treatment can safely reduce seizures.
Hangzhou, ZhejiangAges 18–75 - NCT07253701Recruiting
Epilepsy and gut bacteria: understanding treatment response
This study looks at how the bacteria in your gut relate to how well epilepsy treatments work. It compares people with newly diagnosed epilepsy (who haven't yet started medicine) to healthy people without epilepsy.
GothenburgAges 2–79 - NCT07288788Recruiting
Kidney function in children with epilepsy
This study looks at how well the kidneys work in children who have epilepsy. It may help doctors understand how epilepsy or its treatment affects kidney health.
SohagAges 1 month–15 years - NCT07363603RecruitingPhase 1/Phase 2
Tianasen for GNAO1-related epilepsy and movement disorders
This trial tests a new drug called Tianasen for children with a specific GNAO1 gene change who have seizures and movement problems that haven't improved with standard treatments. The drug is given via a lumbar puncture (spinal tap) and aims to reduce symptoms.
MoscowAges 1–14 - NCT01858285Recruiting
Genetics study for children with epilepsy
This study looks for genetic (inherited DNA) causes of epilepsy in children. It may help your family better understand what could be driving seizures, even if the cause isn’t known yet.
Boston, MassachusettsAges Any age - NCT00041600Recruiting
Brain Development and Genetic Study for Family Members
This research study investigates how genetic factors affect brain development and function in families where members have brain malformations, intellectual disability, or autism. Researchers hope to identify genetic causes that could lead to better understanding and future treatments.
Boston, MassachusettsAges Any age - NCT01403402Recruiting
Study of congenital muscle disease patients and their families
This trial collects health information from patients with certain inherited (genetic) muscle diseases and from their families. It may help researchers better understand the disease and improve care by learning what symptoms and treatments patients experience over time.
Lakewood, CaliforniaAges Any age - NCT02107989Recruiting
MRI and brain scans before epilepsy surgery
This study collects noninvasive brain scan data (mainly MRI, sometimes MEG) from people being evaluated for focal epilepsy surgery, and from healthy volunteers. It aims to build reference “normal” brain images and improve how doctors plan and interpret epilepsy surgery evaluations.
Bethesda, MarylandAges 8–120 - NCT02821260Recruiting
Evaluating epilepsy surgery results in children at a French hospital
This study looks at how well epilepsy surgery works for infants and children treated at the Rothschild Foundation. It mainly depends on whether your child is already scheduled/being treated there and whether you agree to participate.
ParisAges Up to 18 years - NCT02846272Recruiting
Brain scans in children with hard-to-treat epilepsy
This study uses special brain imaging to look at how brain cells and networks work in children with intractable, or hard-to-treat, epilepsy. The goal is to connect the scan findings with what’s found in clinical evaluation to better understand the condition.
Houston, TexasAges birth–18 years - NCT02639325Recruiting
Seizure treatment study for people with brain tumors
This study looks at how a brain tumor-related seizure condition is handled in children and adults. It may be a good option if your seizures started soon after your brain tumor was found or is in the same brain area as your seizure symptoms.
Bethesda, MarylandAges 8–99 - NCT02824822Recruiting
Genetic test study for heart rhythm risk in people with seizures
This study checks whether genetic markers are linked to heart rhythm problems in people with epilepsy or seizure-related events, and in some close relatives. It may help doctors better spot who is at risk for dangerous heart rhythm issues.
Rochester, MinnesotaAges 18–50 - NCT02531880RecruitingPhase 1
MRI test of a brain barrier issue in hard-to-treat epilepsy
This early-phase study uses a special MRI approach to look for signs that the “blood-brain barrier” is breaking down in people with drug-resistant epilepsy. It may help researchers understand what is happening in the brain and guide future treatments, though it is primarily a testing/study study.
Bethesda, MarylandAges 18–60 - NCT02890641Recruiting
Study of brain signals and genes in hard-to-treat epilepsy
This study looks at genetic factors and brain electrical activity in children whose seizures are difficult to control with standard medicines. It also involves exams like MRI and possibly procedures under anesthesia, to better understand seizure causes and help future care.
ParisAges 3 months–25 years - NCT03094312Recruiting
Check how a seizure-brain procedure affects thinking after surgery
This study looks at whether a special brain-recording procedure for difficult-to-control seizures changes a person’s memory, thinking, or other brain skills afterward. It may help doctors understand risks and plan care for people undergoing the procedure.
BronAges 18–65 - NCT02151175Enrolling by invitation
Focused ultrasound to treat medication-resistant temporal lobe seizures
This trial tests a low-intensity focused ultrasound treatment aimed at reducing seizures caused by problems in one side of the hippocampus (a brain area involved in memory and seizures). It’s for people whose seizures have not responded to several seizure medicines and who have been offered a specific type of surgery.
Los Angeles, CaliforniaAges 18–60
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Common questions
- Are there clinical trials for epilepsy?
- Yes. Clin2 currently lists 339 recruiting epilepsy studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a epilepsy trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a epilepsy trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.