Clinical trials
General Population (no Specific Condition or Disease) clinical trials
Below are recruiting general population (no specific condition or disease) clinical trials, each written for real people, not researchers. We’re tracking 10,548 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04633603Enrolling by invitation
Study of attitudes toward fever and fever care changes
This study looks at how people think about fever and how fever care works in the healthcare system. You may be asked to record details of fever episodes at home or in outpatient care to help researchers understand real-world fever management.
PécsAges Up to 100 years - NCT04626167RecruitingEarly Phase 1
Testing a bladder transplant done with a kidney transplant
This early-phase study is testing a combined bladder and kidney transplant approach for people whose bladder problems damage the kidneys. The goal is to see if this treatment can improve bladder and kidney outcomes and be done safely.
Rochester, MinnesotaAges 1–60 - NCT04676100Enrolling by invitation
International registry for cardiac rehabilitation programs
This study collects information about cardiac rehabilitation (CR) programs in lower-resource areas. It helps improve how CR is delivered and understood, especially where healthcare resources and awareness are limited.
DohaAges 18 years+ - NCT04604522Recruiting
Study airway brushing in people with bronchiolitis obliterans
This study collects tiny airway samples during a planned bronchoscopy to better understand bronchiolitis obliterans (a long-term lung complication after transplant). Your samples may help researchers learn how the disease starts and changes over time.
Houston, TexasAges Any age - NCT04681781Enrolling by invitation
Remote study of SLC13A5 deficiency history
This study follows people with SLC13A5 deficiency to better understand how the condition changes over time, using surveys and clinical check-ins done remotely. If you (or your child) have this genetic condition, it may help researchers learn what symptoms to expect and how to track them.
Palo Alto, CaliforniaAges Any age - NCT04645602RecruitingPhase 2
Study of pembrolizumab and lenvatinib for lung papillomas
This early-phase trial tests how well pembrolizumab plus lenvatinib can treat respiratory papillomas that have spread to the lungs. It may help people whose lung disease is caused by human papillomavirus (HPV).
New Haven, ConnecticutAges 18 years+ - NCT04641039Recruiting
Study of scar differences after lumbar disc replacement
This study compares how postoperative scars look and behave after certain lumbar disc replacement surgery. It may help doctors choose approaches that reduce excessive scar-related problems after surgery.
Valencia, ValenciaAges 18–50 - NCT04669717RecruitingPhase 4
Testing antibiotic dosing alongside periodontal treatment
This study tests how antibiotics should be added to standard gum (periodontal) treatment, including dosing and blood-level timing. It may help people whose gum disease is severe, by improving how antibiotics are used with routine dental care.
Geneva, Canton of GenevaAges 18–80 - NCT04680130Enrolling by invitation
Study of brain, genetics, and clinical symptoms in neurodegenerative illness
This study looks at how your symptoms, brain imaging (MRI), and genetic factors relate to neurodegenerative conditions. It may help researchers better understand what causes these illnesses and how to classify them.
Rochester, MinnesotaAges 21 years+ - NCT04664556Recruiting
Study of severe pneumococcal infections in children
This study tracks cases of invasive pneumococcal disease (a serious infection) in children and newborns. It may help clinicians better understand how these infections happen and guide future prevention and treatment.
CréteilAges 1 day–18 years - NCT04601038RecruitingPhase 2
Testing a stress-blocking drug for early Alzheimer's risk
This study tests a new medication, CORT108297, that may help protect the brain from the harmful effects of stress in people at risk for Alzheimer's disease. It is looking for adults age 55 and older who either have mild memory problems or are healthy but have a family history, APOE4 gene, or memory concerns.
Baltimore, MarylandAges 55 years+ - NCT04528355Recruiting
Study of hospital data after stem cell transplant for non-cancer illness
This study collects medical information from people with certain non-cancer conditions who receive a stem cell transplant. It may help doctors better understand transplant outcomes and care, since the study focuses on data collection rather than adding new treatment.
Pittsburgh, PennsylvaniaAges 2 months–60 years - NCT04408430Recruiting
Valve replacement for severe mitral valve disease in high-risk adults
This trial tests a less-invasive way to treat severe mitral valve problems using a transcatheter valve. It may help people who are too high-risk for standard open-heart mitral surgery by improving symptoms and heart function.
Gilbert, ArizonaAges 18 years+ - NCT04569591Recruiting
Using DDAVP with PET scans to find pituitary tumor source
This study tests whether giving DDAVP before a PET scan can help doctors better locate the pituitary problem in people with Cushing disease. It may help confirm where the ACTH-producing tumor is so surgery can be planned more accurately.
Bethesda, MarylandAges 8–99 - NCT04582903Recruiting
Send-in sample collection study for immune response to respiratory viruses
This study collects sent-in samples to better understand how your immune system responds during a COVID-19–like illness and after you recover. It may help researchers learn why some people get sick and others stay uninfected, and how immune protection works over time.
Rockville, MarylandAges 1 day–99 years - NCT04545112Enrolling by invitation
Testing a new heart bypass graft in people needing multi-vessel CABG
This study tests a new way to connect a bypass graft during heart bypass surgery for people with blocked heart arteries. The goal is to see if the new graft can be safely placed and works well enough to improve outcomes compared with the standard approach.
LeuvenAges 18 years+ - NCT04496895Recruiting
Orange peel drink study for reducing body fat
This trial looks at whether a fermented orange peel product can lower body fat in adults. It may help if you have higher body fat and/or fatty liver, and you meet safety and health limits.
Taipei, TaiwanAges 20–65 - NCT04561791Enrolling by invitation
Testing a swallowable scope for early detection of Barrett’s esophagus
This study checks whether a special swallowable “camera capsule” test done in primary care can find early warning changes called Barrett’s esophagus. If it works well, it could make screening easier for people at risk.
Boston, MassachusettsAges 18–75 - NCT04516057RecruitingPhase 3
Tested medicine nabilone for agitation in Alzheimer’s dementia
This Phase 3 trial studies whether nabilone can reduce agitation (restlessness, anger, or difficult behavior) in people with Alzheimer’s dementia. It’s designed for older adults who already have agitation despite standard dementia care.
Calgary, AlbertaAges 55 years+ - NCT04514445Recruiting
Study of genes in people with bicuspid aortic valve
This study looks for genetic (inherited) differences that may be linked to bicuspid aortic valve (BAV). It includes people with BAV and close family members to help understand why BAV happens and whether genes play a role.
KetteringAges 10–99 - NCT04504526RecruitingEarly Phase 1
New imaging for diagnosing lymphoma
This study tests a new imaging method called CXCR4 PET/CT that may help doctors better see and understand lymphomas (a type of blood cancer). It is for people who are newly diagnosed or suspected of having lymphoma and have already had a standard PET/CT.
Fuzhou, FujianAges 18–80 - NCT04518475RecruitingPhase 4
Eltrombopag with rituximab versus eltrombopag alone for ITP
This trial compares two treatment approaches for adults with primary immune thrombocytopenia (ITP), a condition where platelet counts are too low. It looks at whether adding rituximab to eltrombopag helps control ITP better and more safely.
TianjinAges 18–60 - NCT04505618Recruiting
Eye scan study using special imaging for blood-vessel disease
This study uses a detailed eye scan (optical coherence tomography angiography) to look at how blood vessels in the retina are affected. It may help researchers better understand retinal vascular diseases, though some people will be excluded for safety or image-quality reasons.
Baltimore, MarylandAges 18–99 - NCT04506593Recruiting
GI Motility diagnosis registry for people with digestion movement problems
This trial is a registry, meaning it collects information about people being evaluated for problems with how the gut moves. It may help doctors better diagnose gastrointestinal motility disorders in the future.
Indianapolis, IndianaAges Any age
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Common questions
- Are there clinical trials for general population (no specific condition or disease)?
- Yes. Clin2 currently lists 10,548 recruiting general population (no specific condition or disease) studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a general population (no specific condition or disease) trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a general population (no specific condition or disease) trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.