Clinical trials
Glioma clinical trials
Below are recruiting glioma clinical trials, each written for real people, not researchers. We’re tracking 331 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07832734Recruiting
Brain tumor tissue analysis for glioma diagnosis
This study looks at the chemicals and genes in brain tumors called gliomas to find better ways to diagnose and treat them. People with a brain mass that needs surgery may be able to join.
Milan, LombardyAges 18 years+ - NCT07750457Recruiting
Proton versus standard radiation for slow-growing brain tumors
This trial compares two types of radiation therapy (proton beams vs. standard photon x-rays) for people with certain slow-growing brain tumors (gliomas) that have a specific gene change. The goal is to see which type better preserves thinking skills and quality of life while treating the tumor.
EssenAges 18 years+ - NCT04267978RecruitingPhase 2
Test drug combination for recurrent brain tumor growth
This Phase 2 study tests whether adding recombinant human endostatin to temozolomide and irinotecan can slow or control recurrent gliomas (brain tumors) after prior standard treatment. It may help by targeting tumor blood vessel growth while also using chemotherapy to attack cancer cells.
BeijingAges 18–70 - NCT06180434Recruiting
Short-term outcomes of proton vs photon radiation for IDH-mutated gliomas
This study looks at the short-term results of proton and photon radiation therapy in people with IDH-mutated grade 2 or 3 gliomas. It compares the two types of radiation to see how well they work and what side effects might occur.
RotterdamAges 18 years+ - NCT07710040RecruitingPhase 1
Proton radiation before surgery for high-grade brain tumors
This trial tests proton radiation therapy given before surgery for people with a single, high-grade brain tumor. The goal is to see if pre-surgery radiation helps with treatment outcomes.
Obninsk, Kaluga OblastAges 18 years+ - NCT07678684RecruitingPhase 2
Study of HF1K16 plus bevacizumab for recurrent glioma
This trial tests a new combination of two drugs, HF1K16 and bevacizumab, for people whose glioma has come back or grown after prior treatment. It aims to see if this combination can help when standard options are no longer working or tolerable.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT07655869RecruitingEarly Phase 1
Lu177-DOTA-EB-RGD2 therapy for returning high-grade glioma
This trial tests a radioactive drug that targets a protein on tumor blood vessels to treat glioblastoma that has come back after standard treatment. It may help shrink tumors or slow their growth.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07649070RecruitingPhase 2
Virus therapy and low-dose radiation for children with aggressive brain cancer
This trial tests whether a special herpes virus (G207) combined with low-dose radiation can help children with high-grade brain tumors (gliomas). The virus is injected into the tumor to attack the cancer cells while radiation helps boost the effect.
Houston, TexasAges 3–21 - NCT06043765Recruiting
Brain stimulation and memory training for glioma patients
This trial tests a combination of brain stimulation (rTMS) and cognitive strategy training to help improve memory and thinking in people with glioma. If you have a stable brain tumor and notice problems with focus or memory, you may be able to join.
AmsterdamAges 18–80 - NCT07631338Recruiting
Low-Grade Brain Tumors: Treatment Outcomes in Argentina
This study follows adults with low-grade gliomas (slow-growing brain tumors) to understand how often they occur, how long patients survive, and which treatments work best. Researchers will review medical records to learn more about care options.
Buenos Aires, Buenos Aires F.D.Ages 18 years+ - NCT06161610Recruiting
Laser treatment for returning high-grade glioma
This study tests a laser ablation treatment for people whose high-grade glioma (a fast-growing brain tumor) has come back after standard therapy. The goal is to see if this minimally invasive laser procedure can help control the tumor.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06172595RecruitingPhase 2
PET scan to tell tumor growth from treatment effects in brain cancer
This trial tests whether a special PET scan can tell the difference between actual tumor growth and treatment-related changes in people with aggressive brain cancer (high-grade glioma). If you have had radiation and an MRI shows a growing lesion, this study may help clarify the cause.
SingaporeAges 21 years+ - NCT07599371RecruitingPhase 1/Phase 2
Ivoximab and temozolomide for recurring brain tumors
This trial tests a combination of two drugs—ivoximab (a new immunotherapy) and temozolomide (chemotherapy)—to treat gliomas (brain tumors) that have come back or stopped responding to prior treatment. The goal is to see if this combination is safe and effective.
Zhengzhou, HenanAges 18–85 - NCT06736470Recruiting
Fluorescence measurement of brain tumor suction samples
This trial is testing a new way to measure fluorescence in fluid suctioned from the brain during glioma surgery. It may help surgeons better identify tumor tissue.
Kuopio, KuopioAges 18 years+ - NCT06747728Recruiting
Bevacizumab before surgery for new high-grade brain tumors
This trial tests whether giving bevacizumab (a drug that blocks blood vessel growth) before surgery helps treat newly diagnosed high-grade gliomas. It may be an option for adults who have not had prior anti-angiogenic therapy.
Zhengzhou, HenanAges 18 years+ - NCT07488754Recruiting
Targeted radiation therapy for new glioma (grade 3-4)
This trial tests a new type of targeted radiation therapy for people with high-grade glioma (grade 3 or 4) that has not progressed after standard treatment. The therapy uses a radioactive substance attached to a protein that targets tumor cells, aiming to deliver radiation directly to the cancer.
Warsaw, PolandAges 18–80 - NCT07488780Recruiting
Language brain training before brain surgery
This study tests whether a special MRI training session can help preserve your language abilities before brain surgery. It uses real-time feedback to strengthen the language network in your brain.
New Haven, ConnecticutAges 18 years+ - NCT06720727Recruiting
Radiation therapy for children with histone-altered midline glioma
This trial tests a type of radiation therapy called craniospinal irradiation for children and teenagers newly diagnosed with a specific brain tumor (diffuse midline glioma with H3 histone alteration). The goal is to see if this radiation can help control the tumor.
MumbaiAges 3–18 - NCT07464925RecruitingPhase 1
Testing GLIX1 for adults with returning high-grade glioma
This trial tests a new drug called GLIX1 to find a safe dose for people whose high-grade glioma (a fast-growing brain tumor) has come back or is getting worse after earlier treatments. It may be an option if you've had no more than two prior treatments.
Tampa, FloridaAges 18 years+ - NCT07465796Recruiting
Testing a new device during brain tumor surgery
This trial is testing a new tool called the CIPHER System during brain surgery for people with a newly diagnosed glioma. It looks at how well the tool works and how safe it is when used during the procedure.
Melbourne, VictoriaAges 18–75 - NCT07468136RecruitingPhase 1/Phase 2
Retifanlimab with or without DFMO for progressive high-grade gliomas
This study tests a combination of two drugs—retifanlimab (an immunotherapy that helps your immune system fight cancer) and DFMO (a medicine that may stop tumor growth)—in people with high-grade brain tumors that are growing. Participants will receive these treatments before and after their planned surgery.
Rochester, MinnesotaAges 18 years+ - NCT06794736Recruiting
Study on metabolic profiles in lower-grade gliomas
This study looks at how lower-grade gliomas (a type of slow-growing brain tumor) use energy. It may help doctors better understand the tumor and choose the best treatment for you.
Bari, ApuliaAges 18 years+ - NCT06801730RecruitingPhase 2
Irinotecan liposomes plus bevacizumab for recurrent glioma
This trial tests a combination of two medications—irinotecan liposomes (a chemotherapy drug wrapped in fat particles) and bevacizumab (a drug that cuts off blood supply to tumors)—for people whose glioma (a type of brain tumor) has come back or worsened after initial treatment. The goal is to see if this combination can help control the tumor.
Lishui, ZhejiangAges 18–75 - NCT07447531Recruiting
MRI and blood test to track brain tumor changes
This study tests whether a special MRI scan and a blood test can help predict how a specific type of brain tumor (malignant glioma) changes over time. It is for people starting standard radiation and chemotherapy on a special machine that combines MRI and radiation.
Iowa City, IowaAges 21 years+
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Common questions
- Are there clinical trials for glioma?
- Yes. Clin2 currently lists 331 recruiting glioma studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a glioma trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a glioma trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.