Clinical trials
Goal Directed Therapy clinical trials
Below are recruiting goal directed therapy clinical trials, each written for real people, not researchers. We’re tracking 21 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06156943Recruiting
Fluid monitoring during lung surgery for high-risk patients
This study tests a new way to monitor your body's fluid levels during lung surgery, especially for patients who are at higher risk for complications. The goal is to improve recovery and reduce problems after surgery.
BronAges 18–80 - NCT07303855Recruiting
Better fluid management after major abdominal surgery
This study compares two ways of giving fluids to people after major abdominal surgery in the ICU. It will see if using a measure of how much blood the heart pumps (cardiac index) is better than the usual method based on vein pressure.
Jakarta Pusat, DKI JakartaAges 18–65 - NCT05336357Recruiting
Non-invasive treatment plan for septic shock
This study tests a non-invasive, goal-based treatment approach for people with septic shock—an emergency condition caused by severe infection. It may help by using blood-pressure and circulation targets to guide care without more invasive procedures.
São PauloAges 18 years+ - NCT06367205Recruiting
Fluid and blood pressure management in kidney transplant
This trial tests a way to manage fluids and blood pressure during kidney transplant surgery to see if it improves recovery. It may be an option for people getting a kidney from a deceased donor.
Zhengzhou, HenanAges 18 years+ - NCT06510543Recruiting
Nutrition drink before and after esophageal cancer surgery
This study tests a special nutrition drink (ORAL IMPACT®) before and after esophageal cancer surgery. It aims to help patients who are malnourished get stronger and recover better.
Beijing, Beijing MunicipalityAges 18–80 - NCT06747546Enrolling by invitation
Oxygen-based blood flow management after heart surgery
This study is testing a new way to manage blood flow after heart surgery in children with congenital heart disease. The goal is to make sure the body gets the right amount of oxygen to help recovery.
Minhang, Shanghai MunicipalityAges 1 week–18 years - NCT04266574Recruiting
Blood pressure–guided care for older or frail surgical patients
This study tests a goal-based blood pressure treatment approach during major surgery for people at higher risk (often older or frail with high blood pressure). The goal is to see if this BRAIN-targeted strategy can improve how patients do after surgery.
Rozzano, MilanAges 18 years+ - NCT03469440Recruiting
Targeted oxygen monitoring during children’s heart surgery
This trial tests whether a goal-focused monitoring approach can help optimize oxygen levels in the blood during children’s heart surgery using a heart-lung machine. It may help clinicians adjust care more precisely during surgery.
São PauloAges Up to 14 years - NCT05824260Recruiting
Study of risk factors for complications after major surgery
This study looks at patients who've had major abdominal, bone, or blood-vessel surgery to understand what factors make some people more likely to have complications afterward. It analyzes information already collected from hospitals to help doctors better predict and prevent problems.
AmiensAges 18 years+ - NCT05481723RecruitingPhase 3
Lung ultrasound to guide fluid and blood pressure during surgery
This Phase 3 study tests whether using a lung ultrasound scan during surgery can better guide blood pressure and fluid needs. It may help stabilize patients during long operations and reduce complications related to poor circulation or fluid balance.
AmiensAges 18 years+ - NCT06871150Recruiting
Fluid management during major abdominal cancer surgery
This trial compares three different approaches to guiding fluid management during major abdominal cancer surgery. The goal is to find the best way to maintain stable blood pressure and organ function during the procedure.
Bergamo, ItalyAges 65 years+ - NCT04432025Recruiting
Medication after weight-loss surgery for type 2 diabetes
This trial looks at whether a specific diabetes medicine given after bariatric (weight-loss) surgery can improve blood sugar control in people with type 2 diabetes. You might be considered if you are eligible for this surgery and meet the weight criteria.
DublinAges 18 years+ - NCT06080178RecruitingPhase 4
Goal-directed fluids during breast reconstruction surgery
This trial tests a precise fluid management strategy during DIEP flap breast reconstruction to improve outcomes. It aims to reduce complications and improve recovery.
Ghent, East FlandersAges 18–70 - NCT06459141Recruiting
Blood Thinning During Bone Tumor Surgery
This study tests whether a technique that thins your blood during surgery can help people having bone tumor removal. It may reduce the need for blood transfusions.
Hangzhou, ZhejiangAges 18–75 - NCT06468852Recruiting
Fluid management during head and neck cancer surgery
This trial tests whether a specific way of giving fluids during surgery (called goal-directed fluid therapy) can improve recovery after head and neck cancer surgery. It involves having a small tube in your artery to closely watch your blood pressure.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06881498Recruiting
Blood thinning technique for bone tumor surgery
This trial tests a technique called 'acute normovolemic hemodilution' during bone tumor surgery. It involves temporarily thinning your blood by removing some red blood cells and replacing them with fluid, which may reduce the need for blood transfusions.
Hangzhou, ZhejiangAges 18–75 - NCT07070973Recruiting
Managing blood flow during ovarian cancer surgery
This study tests a proactive approach to monitoring and managing blood flow during surgery for ovarian cancer, including a heated chemotherapy bath (HIPEC). It aims to improve recovery by keeping your blood pressure and circulation stable.
RomeAges 18 years+ - NCT07583927Enrolling by invitation
Blood Flow Monitoring During Stomach Cancer Surgery
This study examines how blood flow changes in tiny vessels under the tongue during a specific type of fluid management strategy in patients undergoing stomach cancer surgery. Researchers hope this information may help improve surgical outcomes and patient safety.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT07225868Recruiting
Coaching to boost cognitive rehab in MS
This trial tests if coaching in goal-directed behavior can improve cognitive rehabilitation for people with relapsing-remitting or secondary progressive MS. It aims to help patients better manage daily tasks and thinking challenges.
Buffalo, New YorkAges 18–65 - NCT05837455RecruitingPhase 2
Biomarker-guided treatment for early breast cancer before surgery
This trial looks at whether using tumor test results (biomarkers) can help guide the best hormone treatment and chemotherapy before surgery. It focuses on people with stage II or III, ER-positive, HER2-negative breast cancer, with the goal of improving how well the tumor responds before it is removed.
St Louis, MissouriAges 18 years+ - NCT07128446Recruiting
Goal setting with COPM in the PICU
This trial is testing a new way to set goals for children in the pediatric intensive care unit. Researchers want to see if a tool called COPM helps caregivers and therapists work together to choose the most important rehab goals.
Seoul, Gangnam-guAges 1–18
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Common questions
- Are there clinical trials for goal directed therapy?
- Yes. Clin2 currently lists 21 recruiting goal directed therapy studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a goal directed therapy trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a goal directed therapy trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.