Clinical trials
Heart Defects, Congenital clinical trials
Below are recruiting heart defects, congenital clinical trials, each written for real people, not researchers. We’re tracking 43 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07424976Enrolling by invitation
Early brain injury detection after infant heart surgery
This study looks for early signs of brain injury in infants after heart surgery that uses a heart-lung machine. It aims to improve monitoring and care for babies with congenital heart disease.
LjubljanaAges 1 week–1 year - NCT06175104Recruiting
HeartGPS: Support for parents after a prenatal heart diagnosis
This study tests a counseling program for parents whose unborn baby has a serious heart condition called single ventricle. The program aims to help parents manage stress and support their baby's development before and after birth.
Los Angeles, CaliforniaAges 18 years+ - NCT06267859RecruitingEarly Phase 1
New treatments for frequently ill children
This study tests new ways to help children who get sick often (frequently ill children) feel better and avoid common illnesses. It focuses on children who do not have severe chronic diseases.
Tashkent, Yunus-obad DistrictAges 3 days–15 years - NCT06741189Recruiting
Home monitoring tool for infants with heart defects
This trial tests a home monitoring tool for babies and toddlers with congenital heart defects who had surgery at Nantes University Hospital. It aims to see if remote tracking can help improve care at home.
NantesAges birth–3 years - NCT07019857Recruiting
Thymus removal and immunity in infant heart surgery
This study looks at how removing the thymus gland during infant heart surgery affects the immune system. It compares babies who have their thymus removed with those who have heart surgery without removing it, and with babies having other types of surgery.
NantesAges Up to 6 months - NCT06034392Enrolling by invitation
CHAMP app study for kids with complex heart conditions
This study tests whether using a mobile app to monitor children with complex health conditions at home can help their care team. Families will use the app to share health information instead of only in clinic visits.
Washington D.C., District of ColumbiaAges Up to 18 years - NCT06626672Recruiting
Digital Health Program for Kids with Heart Defects
This study uses digital tools to promote healthy habits in children (ages 8–14) with congenital heart disease. It aims to support both the child and their family in staying active and well.
MünchenAges 8–14 - NCT05637814Recruiting
Screening for critical heart defects with extra blood flow checks
This trial tests if adding blood flow measurements to standard pulse oximeter screening better detects critical congenital heart disease in fetuses and newborns. It may help identify babies who need early heart care.
Davis, CaliforniaAges birth–3 weeks - NCT07716488Recruiting
Screening for high cholesterol in children with chronic conditions
This study screens children and teens with certain chronic conditions (like heart defects or inflammatory bowel disease) for early signs of high cholesterol or other lipid problems. The goal is to find and manage these risks sooner.
JenaAges 6–18 - NCT07375602Recruiting
AI tool to predict complications after VSD closure in children
This study uses artificial intelligence to predict complications in children who have had a specific type of hole in the heart (called a perimembranous ventricular septal defect) repaired with a catheter-based procedure. The goal is to help doctors better identify which children might have problems after the procedure.
Shanghai, Shanghai MunicipalityAges Up to 18 years - NCT05373498Recruiting
Registry for children’s heart emergencies after resuscitation
This trial is a registry that collects information about children (under 18) who have congenital heart problems and need resuscitation with chest compressions. It helps doctors understand these emergencies and may improve future care for similar patients.
Leipzig, SaxonyAges Up to 18 years - NCT06690151Recruiting
Babies with heart defects and development support
This study looks at how a serious heart condition before birth may affect a baby's brain development. It follows babies and their parents to better understand and support these children as they grow.
Nantes, Loire AtlantiqueAges Any age - NCT05386173Recruiting
Tests fetal aortic valve balloon surgery for severe narrowing
This trial studies whether doing a procedure before birth to open a baby’s aortic valve improves outcomes. It compares this approach in a specific group of pregnancies with severe heart flow problems seen on ultrasound.
San Francisco, CaliforniaAges 5 months–7 months - NCT03775954Recruiting
Fetal heart testing in high-risk pregnancies after baby loss
This study checks unborn babies’ heart signals using special scans during pregnancy and then checks the baby’s heart shortly after birth. It may help researchers understand why certain high-risk pregnancies can lead to fetal demise and improve care.
Madison, WisconsinAges 18 years+ - NCT06771687Recruiting
High-intensity interval training for heart conduit patients
This study tests whether high-intensity interval training (short bursts of intense exercise) can improve heart function and fitness in people who have a surgical tube (conduit) connecting their right ventricle to their pulmonary artery. It aims to find a safe and effective exercise program for those with this type of congenital heart condition.
Nijmegen, GelderlandAges 12–45 - NCT06775639Recruiting
Can we skip a heart artery test before surgery?
This study looks at whether people with adult congenital heart disease can skip a pre-surgery artery test (coronary angiography) if they already had a CT scan. If you qualify, you might help doctors find safer, simpler ways to prepare for heart surgery.
BolognaAges 18 years+ - NCT07095829Recruiting
Predicting circulation after birth for severe pulmonary valve blockage
This study looks at babies with a severe heart defect where the pulmonary valve is blocked and the wall between the heart's lower chambers is intact. It aims to predict how well blood will flow after birth using ultrasound images taken during pregnancy.
MadridAges 4 months–6 months - NCT07255144Recruiting
Ultrafast ultrasound imaging for children's heart conditions
This study tests a new, faster ultrasound technique to see heart structure and blood flow in children with or without congenital heart disease (CHD). It aims to improve imaging without risk, using a short scan during a regular check-up.
Pessac, FranceAges Any age - NCT00243776Recruiting
Study of heart tissue changes during certain heart surgeries
This study collects and analyzes small samples of heart tissue during specific heart operations in babies or children. The goal is to better understand how the heart develops after birth, which could improve future care.
Atlanta, GeorgiaAges Up to 20 years
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Common questions
- Are there clinical trials for heart defects, congenital?
- Yes. Clin2 currently lists 43 recruiting heart defects, congenital studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a heart defects, congenital trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a heart defects, congenital trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.