Clinical trials
Heart Failure Patients clinical trials
Below are recruiting heart failure patients clinical trials, each written for real people, not researchers. We’re tracking 765 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05568069Recruiting
Study of defibrillator implants for non-ischemic weak heart
This study looks at whether implantable defibrillators can reduce dangerous heart rhythms in people with non-ischemic cardiomyopathy (heart weakness not caused by blocked heart arteries), a heart scar, and very low pumping strength despite best treatment. It compares different approaches to choosing which patients should receive these devices.
High Wycombe, BuckinghamshireAges 18 years+ - NCT05537467Recruiting
Music during exercise for people with heart failure
This trial tests whether listening to music while you exercise can improve how well you can exercise when you have heart failure. It is mainly looking for adults who can safely do an exercise test and communicate in English.
Lexington, KentuckyAges 18 years+ - NCT05508035RecruitingPhase 3
Testing sacubitril/valsartan vs ramipril for heart failure
This trial compares two blood-pressure and heart-failure medicines: sacubitril/valsartan versus ramipril, to see which improves heart pumping and heart structure over time. It’s aimed at people with ischemic (blocked-artery) heart failure with mid-range ejection fraction and ongoing symptoms.
Krakow, Lesser Poland VoivodeshipAges 18 years+ - NCT05525663Recruiting
Rehab for older adults after heart failure with strong pumping
This trial studies whether a physical rehabilitation program helps older adults recover and function better after a recent hospital stay for heart failure when the heart’s pumping strength is preserved. It may help you regain walking ability and daily independence after your episode.
Winston-Salem, North CarolinaAges 60 years+ - NCT05417490Recruiting
Study of why people join PRADO and telemedicine for heart failure
This study looks at what influences whether people with heart failure choose to join PRADO and telemedicine support after a hospital stay. Your answers can help the team understand barriers and improve future participation and care.
MontpellierAges 18 years+ - NCT05392764RecruitingPhase 3
SGLT2 medicine for high-risk people after sudden worsening heart failure
This Phase 3 trial tests whether starting an SGLT2 inhibitor early in the hospital can improve outcomes for people at high risk after acute (sudden) heart failure. If you qualify, you would be randomized to receive the study medicine or standard care, started within 12 hours of admission.
Anjo, Aichi-kenAges 20 years+ - NCT05276219RecruitingPhase 4
Vasodilators or diuretics for acute heart failure
This trial compares two treatments for sudden heart failure symptoms like severe shortness of breath. It aims to see whether opening blood vessels or using a water pill works better to relieve congestion and improve breathing.
Copenhagen, CopenhagenAges 18 years+ - NCT05255172Enrolling by invitation
Exercise program for heart failure with preserved or reduced pumping
This trial tests whether a structured exercise program can help people with heart failure. It focuses on people who are currently not very active, aiming to improve symptoms and heart/fitness measures safely.
LundAges 50–90 - NCT02973633RecruitingEarly Phase 1
Heart failure MRI brain-wave images after heart trouble
This early-phase study uses a special MRI scan to look at the heart in people with heart failure (and related heart changes). It aims to see whether these MRI results can better characterize heart disease and help doctors understand what’s going on.
Charlestown, MassachusettsAges 18–85 - NCT05086978Enrolling by invitation
Retina camera test in people with heart failure
This study uses a simple camera to take pictures of the back of your eye (retina) to see how useful retinal imaging might be in people with heart failure. You may also be invited as a healthy control, depending on the group you belong to.
Cleveland, OhioAges 18 years+ - NCT05064709Recruiting
Test device for heart failure symptoms in some patients
This study tests whether a heart-related device called CCM can improve symptoms and daily function in people with heart failure and a moderately reduced pumping strength. It may help if you’ve had recent heart-failure-related hospital care or urgent treatment and your heart and overall health fit the study limits.
Birmingham, AlabamaAges 18 years+ - NCT04941794Recruiting
Test heart-related blood markers in people with type 2 diabetes
This study looks at blood tests (called biomarkers) to see if they can help predict chronic heart failure risk. It focuses on adults with type 2 diabetes over age 50 who do not already have certain heart conditions.
HjørringAges 50 years+ - NCT04829617Recruiting
Program to improve daily habits in heart failure
This trial studies a program designed to help people with heart failure improve health habits like diet, exercise, and taking medicines. It may help you feel better and stay on track if your current routines are hard to follow.
Boston, MassachusettsAges 18 years+ - NCT04768322Recruiting
LVAD versus standard heart failure medicines in advanced patients
This trial compares an LVAD device (a pump placed in the chest) plus medicines versus medicines alone for people with advanced, end-stage heart failure. It aims to see which approach works better to help patients live and stay out of the hospital.
BesançonAges 18 years+ - NCT04396899RecruitingPhase 1/Phase 2
Stem cell heart patch for advanced heart failure
This early-phase study tests a lab-made heart tissue (“engineered myocardium”) placed surgically to help the heart work better in people with advanced heart failure. It mainly checks safety first, and also looks for signs the patch can improve heart function in selected patients.
Göttingen, Lower SaxonyAges 18–80 - NCT04405583Recruiting
Follow-up study for a heart device in heart failure patients
This study follows people with chronic heart failure to see how well an implanted device (called the Occlutech AFR) works and whether it is safe over time. It may help doctors better understand who benefits and how to manage treatment safely.
BesançonAges 18 years+ - NCT03999138Recruiting
MRI study of lung fluid changes in acute heart failure
This study uses MRI scans to measure lung fluid (pulmonary edema) in people hospitalized for acute heart failure. It aims to see how well the lung fluid responds to standard treatments like water pills (diuretics) given in the first couple of days.
Edmonton, AlbertaAges 18 years+ - NCT03984591Enrolling by invitationPhase 4
Compare spironolactone vs eplerenone for heart failure patients
This study uses Denmark’s heart failure registry to compare two common tablet medicines—spironolactone and eplerenone—for people with symptomatic systolic heart failure. It aims to see which one leads to better health outcomes over time.
CopenhagenAges Any age - NCT03775577Recruiting
Exercise testing study for people with heart failure
This study looks at exercise intolerance in heart failure, using heart and lung tests to understand how symptoms affect activity. It may help researchers better identify what limits exercise and how heart failure impacts quality of life.
Baltimore, MarylandAges 21 years+ - NCT03586336Recruiting
Remote lung fluid monitoring to guide heart failure treatment
This study tests a wearable vest that measures fluid in your lungs to help doctors adjust water-pill treatments for heart failure. It aims to reduce hospital stay and improve recovery.
San Francisco, CaliforniaAges 18 years+ - NCT03480633Recruiting
Heart failure precision medicine registry
This registry collects health and heart-related information to better understand heart failure (with preserved or reduced pumping strength) and guide more precise care. You may be asked to share tests and results, and help researchers learn which patterns match different types of heart failure.
Boston, MassachusettsAges 18 years+ - NCT03142152Recruiting
Mitral valve implant for heart failure with leaky mitral valve
This trial tests whether a device called the Carillon Mitral Contour System can help people with heart failure caused by a mild-to-moderate leaky mitral valve. You’d be compared against a control group, and the goal is to improve heart failure symptoms and outcomes.
Gilbert, ArizonaAges 18 years+ - NCT03103932Recruiting
Blood test–guided discharge for people hospitalized with heart failure
This trial checks whether using a blood test (a “biomarker”) can help doctors decide when it’s safe to send people home after a hospital stay for worsening heart failure. It may help reduce avoidable readmissions while keeping you safe.
Ottawa, OntarioAges 18 years+ - NCT02368041Recruiting
Near-infrared scan test in children with heart failure
This study tests whether a near-infrared “light scan” on the hand can help doctors in children with heart failure who are stable on their usual medications. It may give additional information about blood flow and circulation in the body without using invasive procedures.
Gainesville, FloridaAges Up to 25 years
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Common questions
- Are there clinical trials for heart failure patients?
- Yes. Clin2 currently lists 765 recruiting heart failure patients studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a heart failure patients trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a heart failure patients trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.