Clinical trials · San Diego, CA
Heart failure clinical trials in San Diego
We’re tracking 31 recruiting heart failure studies with a site in or near San Diego — including Phase 1/Phase 2, Phase 3 and Phase 4 studies, each written for real people, not researchers.
Recruiting studies near San Diego
- NCT06736574RecruitingPhase 3
Study of omecamtiv mecarbil for chronic heart failure with very weak heart pump
This study tests an investigational medicine (omecamtiv mecarbil) for people with chronic heart failure and very low pumping strength. It looks at whether the drug can help prevent heart failure events or the need for stronger treatments.
San Diego, CaliforniaAges 18–85 - NCT06033950RecruitingPhase 3
A study of finerenone for heart failure patients who can't take standard MRA drugs
This study tests whether finerenone, a new type of drug, can help people with heart failure who cannot take standard steroid-based MRAs (a kind of heart medication) because of side effects or other reasons. It aims to see if it improves symptoms and is safe for you.
San Diego, CaliforniaAges 18 years+ - NCT07730268Enrolling by invitation
Vivio at-home study for heart failure monitoring
This study tests a home monitoring device (Vivio) for people who already have a CardioMEMS implant to check if the new device can track your heart health easily at home.
San Diego, CaliforniaAges 21 years+ - NCT07037459RecruitingPhase 3
A study of a new drug for heart failure with obesity
This trial tests a medication called maridebart cafraglutide for people with heart failure (where the heart doesn't pump as well as it should) and obesity. The goal is to see if it can help improve symptoms and outcomes.
San Diego, CaliforniaAges 18–99 - NCT06812533Recruiting
Testing a new approach for heart failure with weak pump
This study tests a new device or procedure to help people with heart failure and a weak heart pump. If you have a low ejection fraction and are on standard medications, you may be able to join.
San Diego, CaliforniaAges 18 years+ - NCT06935370RecruitingPhase 3
Testing vicadrostat with empagliflozin for heart failure with weak pump
This trial tests a new drug called vicadrostat combined with another drug, empagliflozin, for people with heart failure and a weak heart pump. It aims to see if this combination helps improve symptoms and outcomes.
San Diego, CaliforniaAges 18 years+ - NCT04703842RecruitingPhase 1/Phase 2
Study drug effect on heart muscle calcium in advanced heart failure
This trial tests a treatment intended to improve how heart muscle cells handle calcium, which may help heart failure symptoms and heart function. It is mainly for people with advanced heart failure and a low pumping strength of the heart.
San Diego, CaliforniaAges 18–80 - NCT04262830Recruiting
Heart scans to predict future heart failure after chemotherapy
This trial uses detailed heart imaging (a special MRI scan) to see how chemotherapy may have affected your heart and to predict who could develop heart failure later. If you qualify, it may help your care team better monitor your heart health over time.
San Diego, CaliforniaAges 13–39 - NCT00271180Recruiting
Tracks long-term performance of Medtronic heart devices
This study follows how well certain Medtronic heart devices work over the long term. You may be included if you have a qualifying Medtronic implant and the research team can reliably get your implant and follow-up information.
San Diego, CaliforniaAges Any age - NCT03142152Recruiting
Mitral valve implant for heart failure with leaky mitral valve
This trial tests whether a device called the Carillon Mitral Contour System can help people with heart failure caused by a mild-to-moderate leaky mitral valve. You’d be compared against a control group, and the goal is to improve heart failure symptoms and outcomes.
San Diego, CaliforniaAges 18 years+ - NCT06677060RecruitingPhase 3
Study of baxdrostat plus dapagliflozin for heart risk in type 2 diabetes
This study tests whether a new drug called baxdrostat, when added to the diabetes medicine dapagliflozin (Farxiga), can prevent heart failure and heart-related death in people with type 2 diabetes, high blood pressure, and existing heart or blood vessel disease. You may be able to join if you have type 2 diabetes, heart or blood vessel disease, high blood pressure, and at least one extra risk factor for heart failure.
San Diego, CaliforniaAges 40 years+ - NCT07567001RecruitingPhase 3
Testing NNC0487-0111 for Heart Failure and Obesity
This study tests whether a new medication called NNC0487-0111 can help people with heart failure who also have obesity. Researchers will compare it to a placebo (inactive pill) to see if it improves heart function and overall health.
San Diego, CaliforniaAges 18 years+ - NCT06307652RecruitingPhase 3
Testing a new heart failure and kidney treatment combo
This study tests a new combination of two medicines (balcinrenone and dapagliflozin) for people with heart failure and reduced kidney function. The goal is to see if this combination helps improve heart and kidney health better than current treatments.
San Diego, CaliforniaAges 18–130 - NCT01790152Recruiting
Dexrazoxane study to monitor heart damage in cancer survivors
This study tests dexrazoxane (DRZ) to see how it affects blood and heart-related “biomarkers,” or measurable signs of heart damage, after cancer treatment. It mainly targets survivors who may be at risk for cardiomyopathy (heart muscle weakness) or related heart failure.
San Diego, CaliforniaAges Any age - NCT05685303Recruiting
Testing a treatment for heart failure symptoms with normal pumping ability
This study is looking at a new treatment for people with heart failure where the heart’s pumping strength is not reduced much (HFpEF or HFmrEF), but pressure inside the heart is high during exercise. It may help relieve symptoms in people who still feel unwell during normal activity despite stable standard treatment.
San Diego, CaliforniaAges 40 years+ - NCT07574593Recruiting
Heart Failure Sensor Implant Study
This study tests a small sensor placed in a vein to help monitor and manage heart failure. The sensor tracks fluid buildup in your heart and may help doctors adjust your treatment to keep you feeling better and out of the hospital.
Chula Vista, CaliforniaAges 18 years+ - NCT06008197RecruitingPhase 3
A study of finerenone for hospitalized heart failure patients
This trial tests a medication called finerenone to see if it helps people hospitalized for heart failure live longer and have fewer heart-related problems. It may be an option for those with a certain type of heart failure where the heart's pumping strength is mildly reduced or normal.
Chula Vista, CaliforniaAges 18 years+ - NCT06424288RecruitingPhase 3
Testing vicadrostat plus empagliflozin for heart failure
This study tests whether adding a new study drug called vicadrostat to the standard heart failure medicine empagliflozin helps people with heart failure. It may be a good option if you have heart failure with preserved pumping function and are not already on a medicine called an MRA.
Chula Vista, CaliforniaAges 18 years+ - NCT05064709Recruiting
Test device for heart failure symptoms in some patients
This study tests whether a heart-related device called CCM can improve symptoms and daily function in people with heart failure and a moderately reduced pumping strength. It may help if you’ve had recent heart-failure-related hospital care or urgent treatment and your heart and overall health fit the study limits.
La Jolla, CaliforniaAges 18 years+ - NCT06425848Recruiting
Heart failure monitoring study
This study looks at how a small monitor inside the blood vessel to the lungs helps manage heart failure. It aims to improve care for people with advanced heart failure.
La Jolla, CaliforniaAges 18–100 - NCT05650658Recruiting
Compare two heart pacing options in people with weak heart function
This trial compares two types of “left-side” heart pacing to see which one works better in people with weak heart pumping. It may help guide the best pacing choice for improving heart function and symptoms.
La Jolla, CaliforniaAges 18 years+ - NCT04592445Recruiting
Nerve ablation for right-sided symptoms in HFpEF heart failure
This trial tests a procedure to “turn off” the right greater splanchnic nerve to improve symptoms in people with HFpEF (heart failure with preserved pumping function). If successful, it may reduce shortness of breath and fluid congestion in daily life.
La Jolla, CaliforniaAges 40 years+ - NCT07069738Recruiting
New pacemaker vs standard cardiac therapy for heart failure
This study tests a newer type of pacemaker that paces the heart's left bundle branch area, compared to the usual cardiac resynchronization therapy. It is for people with heart failure who need a combined pacemaker-defibrillator (CRT-D) and have a specific heart rhythm pattern (left bundle branch block) with reduced pumping strength.
La Jolla, CaliforniaAges 18 years+ - NCT03102125RecruitingPhase 4
Testing causes of heart transplant graft problems with scans
This study looks at why heart transplant “grafts” can start to malfunction again after transplant. If you qualify, you may undergo MRI and related heart testing to help researchers find ways to detect or understand graft dysfunction.
La Jolla, CaliforniaAges 18 years+
Hear when a new Heart failure trial opens near San Diego, CA
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Heart failure trials in other cities
Where these studies are running near San Diego
Institutions with a site for the recruiting heart failure studies listed above.
- Scripps Health · 5 studies
- University of California San Diego Health · 5 studies
- San Diego Cardiac Center · 3 studies
- Chula Vista, CA Investigative Site · 2 studies
- Rady Children's Hospital San Diego · 2 studies
- Research Site · 2 studies
- Scripps Clinical Research Services · 2 studies
- Blue Coast Research Center
What taking part in a heart failure study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Looking wider? See all recruiting heart failure studies in California.
Common questions
- Are there heart failure clinical trials near San Diego?
- Yes. We're currently tracking 31 recruiting heart failure studies with a site near San Diego, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a heart failure study near San Diego?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in San Diego to take part?
- Not necessarily. These studies have a site near San Diego, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a heart failure trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New heart failure studies open near San Diego regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.