Clinical trials
Heart failure clinical trials
A condition where the heart can’t pump blood as well as it should. We’re tracking 949 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06052072Enrolling by invitation
Heart failure trial testing nerve treatment for lung pressure
This trial tests a new treatment that uses a device to calm overactive nerves in the lung's blood vessels. It is for heart failure patients who also have high blood pressure in their lungs, to see if it can help them breathe easier and feel better.
Chicago, IllinoisAges 22–85 - NCT07673562Recruiting
A simple test to detect heart failure early in adults over 55
This study tests a simple questionnaire and heart test to find hidden heart failure in people over 55. It aims to catch the condition early so treatment can start sooner.
Saint-Denis, ReunionAges 55 years+ - NCT07265986Recruiting
Comparing robotic remote heart ultrasound to standard care for heart failure
This trial tests whether a robot that performs heart ultrasounds from a distance works as well as a standard in-person ultrasound for managing heart failure. It could help people on the island of Marie-Galante get specialist care without traveling.
Grand-BourgAges 18 years+ - NCT05919342Recruiting
Screening for early heart failure in primary care or at home
This trial tests whether simple screening using a blood test (natriuretic peptides) plus an ultrasound of the heart (echocardiogram) can find early heart failure sooner. Finding it earlier may help doctors start the right management to prevent it from getting worse.
Cleveland, OhioAges 40 years+ - NCT05564689Recruiting
Tests coronary blood flow in heart failure patients with CRT
This study measures how well blood flows in the heart (coronary flow) in people with heart failure with reduced pumping strength and a specific heart rhythm problem called left bundle branch block. It focuses on people who already have a cardiac resynchronization therapy (CRT) device and have stable treatment, to see how coronary flow relates to their heart condition.
AalborgAges 18 years+ - NCT06593327Recruiting
Heart failure screening trial for diabetes patients
This trial helps primary care providers screen and prevent heart failure in people with Type 2 diabetes. It uses a simple blood test to find early signs of heart problems.
Dallas, TexasAges Any age - NCT06241651Recruiting
Comparing two types of pacemakers for heart failure patients
This trial tests if a new pacemaker method (CSP) works better than the standard method (BiVP) for people with heart failure who already have a right ventricular pacemaker and need an upgrade.
Nanjing, JiangsuAges 18–80 - NCT07375433Recruiting
Heart failure and COPD study for patients aged 50 to 70
This trial looks at how heart failure with preserved pumping function affects people who also have COPD. It aims to understand the course of the disease and long-term outlook.
Kazan'Ages 50–70 - NCT06107907Recruiting
Oxygen flow and pressure in heart failure patients
This study tests a new way to measure pressure in your lungs while you receive high-flow oxygen therapy. It may help doctors better understand how to use this treatment in people with heart failure who need extra breathing support.
TaipeiAges 18 years+ - NCT06705023RecruitingPhase 2
Fat-derived cell therapy for heart failure
This study tests whether taking a small amount of your own belly fat (through liposuction), processing it, and injecting the cells back into your heart can improve heart function in people with chronic heart failure due to blocked arteries. The trial is for patients whose heart pumps weakly (ejection fraction of 40% or less) and who are already on standard medications.
AstanaAges 21–80 - NCT07851779RecruitingPhase 4
Stopping heart failure drugs after excellent response to cardiac resynchronization therapy
This trial studies whether patients with non-ischemic cardiomyopathy who have responded extremely well to a special pacemaker (CRT) can safely stop their heart failure medications. It aims to see if their heart function stays stable without these drugs.
L'Hospitalet de Llobregat, BarcelonaAges 18 years+ - NCT06688396Recruiting
Finding early signs of dilated cardiomyopathy with AI and mobile screening
This trial uses a smartphone app to screen first-degree relatives of people with dilated cardiomyopathy (DCM) for early signs of the condition. It aims to detect heart muscle weakness before symptoms start, so that treatment can begin sooner.
Lancaster, PennsylvaniaAges 18 years+ - NCT06921603Recruiting
Ultrasound-guided diuretics for heart failure
This trial tests whether using a bedside ultrasound to guide diuretic treatment improves outcomes in people hospitalized for worsening heart failure. It may help find the right dose of IV diuretics faster.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT05834803Recruiting
Stenting narrowed kidney artery to help high-risk patients
This trial studies whether placing a small stent in a severely narrowed kidney artery can improve outcomes for people with high-risk, artery-hardening kidney blood-flow problems. It focuses on people whose high blood pressure or kidney function has been getting worse despite multiple medications.
Aarhus NAges 18 years+ - NCT05081115Recruiting
Stress echo imaging for people with heart valve or muscle issues
This trial studies a stress echocardiogram (an ultrasound of the heart during stress) to better understand and improve future heart imaging. It may help by comparing how well the test works for different heart conditions.
BeneventoAges 18–75 - NCT05558605Recruiting
AI ultrasound guidance for heart risk management
This trial tests whether using an artificial-intelligence (AI) tool during a heart ultrasound can help guide care for people at risk for heart problems. You might benefit if you have symptoms with exercise or heart risk factors, but you do not already have known heart failure or major heart disease.
Alice Springs, Northern TerritoryAges 45 years+ - NCT02820233Recruiting
Study of a heart-signal drug during bypass surgery
This study looks at a treatment that affects signals between heart cells in people with severe coronary artery disease who are scheduled for bypass surgery. The goal is to see if changing these heart-cell signals can improve heart outcomes around the time of surgery.
Portland, MaineAges 18 years+ - NCT06271577Recruiting
Smartphone ECG for heart attack detection
This study tests whether a smartphone can take a 12-lead ECG (a heart tracing) quickly when someone arrives at the ER with chest pain, to help doctors spot a heart attack sooner.
Rochester, MinnesotaAges 18 years+ - NCT03793257Recruiting
ECMO patient registry for adults in Australia and New Zealand
This is a research registry for adults who need a breathing and/or heart support machine called ECMO while in the hospital. It collects information to better understand who receives ECMO and how patients do over time.
Canberra, Australian Capital TerritoryAges 18 years+ - NCT06620705Recruiting
Pacing options for AF with low heart function
This trial compares two types of pacing for people with permanent atrial fibrillation (AF) and a weak heart pump (ejection fraction less than 50%). It tests whether pacing the left bundle branch area works as well as or better than standard biventricular pacing to improve heart function.
Aarhus N, Aarhus NAges 18 years+ - NCT07705269Recruiting
High-rate fluid removal for fluid overload in dialysis patients
This trial tests whether a faster rate of fluid removal during dialysis can help hospitalized patients with end-stage kidney disease who have severe fluid buildup. It aims to reduce fluid congestion and improve outcomes.
Monterrey, Nuevo LeónAges 18 years+ - NCT06838611Recruiting
Study of patients with severe tricuspid regurgitation
This study is collecting information about people with severe tricuspid regurgitation (a leaky heart valve) who are having a catheter-based repair. The goal is to better understand these patients and how well the procedure works for them.
Warsaw, Masovian VoivodeshipAges 18 years+ - NCT07339007Enrolling by invitation
Validating a heart ultrasound training program for family doctors
This study tests whether a training program helps family doctors use a focused heart ultrasound (FoCUS) to assess patients. If you need a heart ultrasound as part of your regular care, you may be able to join.
Barcelona, CataloniaAges 15 years+ - NCT06954792Enrolling by invitation
Studying heart changes after tricuspid valve replacement
This study looks at how the heart adjusts after a procedure to replace the tricuspid valve (the valve between the right upper and lower heart chambers). It focuses on patients who need medication to support their blood pressure within 24 hours after the procedure, to better understand and manage this unstable period.
New York, New YorkAges 18 years+
Hear when a new Heart failure trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for heart failure?
- Yes. Clin2 currently lists 949 recruiting heart failure studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a heart failure trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a heart failure trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.