Clinical trials
Heart failure clinical trials
A condition where the heart can’t pump blood as well as it should. We’re tracking 981 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07392749Recruiting
Diaphragm pacing via vein during CRT implant
This trial is testing a new way to pace the diaphragm using a special vein in your chest, done at the same time as a standard CRT device implant for heart failure. It aims to see if this approach is safe and works well for helping you breathe.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT01757730Recruiting
MRI test to measure soft tissue stiffness
This trial uses a special type of MRI to estimate how stiff certain soft tissues are in the body. You may benefit by helping doctors better measure tissue stiffness, which can relate to different health problems.
Columbus, OhioAges 18 years+ - NCT00181259Recruiting
MRI scan study of heart muscle chemistry
This trial uses a special MRI scan to look at how the heart muscle uses fuel. It may help researchers understand heart conditions like dilated cardiomyopathy and coronary artery disease, especially in people with reduced heart pumping.
Baltimore, MarylandAges 18 years+ - NCT00733590Recruiting
Study after ICD generator replacement for heart attack patients
This study follows people who had a prior heart attack and later received a replacement ICD (a device that helps prevent sudden dangerous heart rhythms). It is observational, meaning it mainly looks at outcomes and device-related information rather than testing a new drug.
Washington D.C., District of ColumbiaAges 18–85 - NCT01390675Recruiting
Registry for heart valve replacement anesthesia during TAVR
This study tracks patients who get a transcatheter aortic valve implantation (TAVR), a procedure to replace a narrowed heart valve without open-heart surgery. It looks at the type of anesthesia used during the procedure and records outcomes to learn what works best for patients.
Munich, BavariaAges 18 years+ - NCT01999140Recruiting
ICD and CRT-D device registry for patients worldwide
This trial is a real-world registry that collects information from people who receive an implantable heart defibrillator or related device. It helps doctors understand how these devices are used and how patients do over time.
Washington D.C., District of ColumbiaAges Any age - NCT01790152Recruiting
Dexrazoxane study to monitor heart damage in cancer survivors
This study tests dexrazoxane (DRZ) to see how it affects blood and heart-related “biomarkers,” or measurable signs of heart damage, after cancer treatment. It mainly targets survivors who may be at risk for cardiomyopathy (heart muscle weakness) or related heart failure.
Birmingham, AlabamaAges Any age - NCT02818517Recruiting
Cardio-oncology checkup to understand heart side effects
This study looks at how cancer treatments may affect the heart (“cardiotoxicity”) and how patients are monitored and managed. You might benefit by getting close heart-related follow-up as part of the care plan.
Tel AvivAges 18 years+ - NCT02448485Recruiting
Measuring Troponin T blood levels in aortic valve narrowing
This study looks at a blood test called high-sensitivity troponin T in people with aortic stenosis (a narrowed heart valve). The results may help doctors understand heart strain or risk in this condition.
Innsbruck, TyrolAges Any age - NCT02306200Recruiting
A study to improve heart and aorta health
This trial looks at ways to improve cardiovascular (heart and blood vessel) health, especially conditions that affect the aorta, such as aneurysms, or vascular problems that may run in families. If you have an aortic-related or other cardiovascular diagnosis (or you’re a healthy comparison participant), you may be invited to take part in this health-improvement program.
Ann Arbor, MichiganAges Any age - NCT02610426Recruiting
Genetic testing to study who develops heart failure during breast cancer therapy
This study uses DNA genetic testing to find DNA changes that might explain why some people develop heart failure (CHF) after breast cancer treatment with certain medicines. It may help researchers understand risk and improve care for future patients.
Boston, MassachusettsAges Any age - NCT02856620Recruiting
Study heart function and frailty in people with aortic valve narrowing
This study looks at how heart mechanics, blood markers, and frailty relate to symptoms and heart measurements in people with aortic stenosis (a stiff, narrowed heart valve). It may help doctors better understand who is at higher risk and how disease changes over time.
Montreal, QuebecAges 18 years+ - NCT07252856Recruiting
Digital support for heart rehab (phase III)
This trial tests a digital tool to help people with heart disease continue their cardiac rehabilitation at home during the maintenance phase. It's for people who have already completed the earlier rehab phase and are ready for long-term support.
LeuvenAges 18 years+ - NCT07656454RecruitingPhase 1
Comparing two ways to give CDR132L in healthy volunteers
This study measures how well the drug CDR132L enters the blood when injected under the skin, compared to injection into a vein. It is done in healthy volunteers to find the best way to give the drug.
BerlinAges 18–55 - NCT02683681Enrolling by invitation
Create a heart tissue and blood sample registry
This study collects blood and/or heart tissue samples from certain people getting heart procedures or with a long-term heart pump. The goal is to store these samples for future research that may improve care for heart failure.
Ages 18 years+ - NCT07403669Recruiting
Heart, kidney, and metabolic health assessment study
This trial offers a health assessment and empowerment program for adults who have heart, kidney, or metabolic conditions like diabetes or heart disease. It aims to help you better manage your health.
Chandler, ArizonaAges 18 years+ - NCT07413198Recruiting
Combined home and clinic exercise coaching for heart failure
This trial tests a program that combines home-based and clinic-based exercise coaching to help people with heart failure get more active. It aims to improve health and quality of life.
Winston-Salem, North CarolinaAges 55 years+ - NCT07443696RecruitingPhase 2
Heart imaging test to see if bypass surgery could help
This study uses two imaging scans to see if parts of your heart muscle are still alive but not working well. This could help doctors decide if you might benefit from heart bypass surgery.
Beijing, Beijing MunicipalityAges 18–85 - NCT07458074Recruiting
Italian Study on Radial VAD Support
This study looks at how well continuous-flow heart pumps (VADs) work in people with advanced heart failure. It aims to improve care and outcomes for adults receiving these devices.
Bergamo, BergamoAges 18 years+ - NCT07476703Recruiting
Extended study on the SCAPIS Stockholm reexamined group
This trial studies data and samples from people already taking part in the main SCAPIS reexamination study in Stockholm. It looks for new findings to help understand heart and lung health.
StockholmAges 56–74 - NCT05672836RecruitingPhase 4
Enavogliflozin after TAVR for heart narrowing with mild heart weakness
This trial tests enavogliflozin (a diabetes medication that may help the heart) in people who have had a TAVR procedure for severe aortic stenosis. It looks at whether the medicine can improve outcomes for people with symptoms and mildly reduced or preserved pumping function.
Bucheon-siAges 19 years+ - NCT06241430Recruiting
CardioClip study: testing a new valve repair for leaky heart valve
This study tests a new clip procedure (CardioClip) to repair a leaky mitral valve in people with heart failure. It aims to see if the clip can improve symptoms and heart function.
New York, New YorkAges 18–90 - NCT07393009Recruiting
Study of a new left bundle branch area pacing system
This study tests a new type of pacemaker system that delivers pacing to the left side of the heart through a lead placed deep in the wall between the lower chambers. The goal is to see if this approach works well for people who need a pacemaker or CRT.
AdelaideAges 18 years+ - NCT07601087RecruitingPhase 1
Safety Study of HRS-7156 in Healthy Adults
This is an early-stage safety study of an experimental drug called HRS-7156 in people with no serious health conditions. Researchers will monitor how your body tolerates the drug and how it moves through your system.
Shanghai, Shanghai MunicipalityAges 18–55
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Common questions
- Are there clinical trials for heart failure?
- Yes. Clin2 currently lists 981 recruiting heart failure studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a heart failure trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a heart failure trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.