Clinical trials
Heart failure clinical trials
A condition where the heart can’t pump blood as well as it should. We’re tracking 949 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04641416Recruiting
Ultrasound test for people with HeartMate 3 blood pumps
This study checks whether a noninvasive ultrasound-based method can help diagnose what’s going on in people with a HeartMate 3 blood pump. It may help detect important pump-related changes while keeping the process safer for certain high-risk situations.
ViennaAges 18–75 - NCT04676100Enrolling by invitation
International registry for cardiac rehabilitation programs
This study collects information about cardiac rehabilitation (CR) programs in lower-resource areas. It helps improve how CR is delivered and understood, especially where healthcare resources and awareness are limited.
DohaAges 18 years+ - NCT04664686Recruiting
Compare two heart-rhythm strategies after CRT for atrial fibrillation
This study looks at whether a “rate control” or “rhythm control” approach works better for people with CRT devices who still have atrial fibrillation. It aims to improve heart failure symptoms and help the heart pace more effectively.
LondonAges 18–85 - NCT04600115RecruitingEarly Phase 1
New MRI methods for heart failure with preserved pumping function
This study tests advanced MRI techniques to better understand heart failure with preserved ejection fraction (HFpEF), a condition where the heart pumps normally but still doesn't work well. It may help improve diagnosis and treatment for patients with this type of heart failure.
Salt Lake City, UtahAges 18 years+ - NCT04592445Recruiting
Nerve ablation for right-sided symptoms in HFpEF heart failure
This trial tests a procedure to “turn off” the right greater splanchnic nerve to improve symptoms in people with HFpEF (heart failure with preserved pumping function). If successful, it may reduce shortness of breath and fluid congestion in daily life.
Birmingham, AlabamaAges 40 years+ - NCT04493385Recruiting
Heart transplant after a hepatitis C–positive donor
This trial follows people who receive a heart from a donor whose blood tested positive for hepatitis C. It also includes people getting a heart transplant again, and it aims to learn about outcomes and safety for these specific transplant situations.
Dallas, TexasAges 18 years+ - NCT04419480Recruiting
Monitoring to help prevent complications after cardiogenic shock
This study tests a special monitoring approach (likely using an implanted device) to help prevent serious complications after you survive cardiogenic shock in the hospital. It may help the care team detect problems earlier so treatments can start sooner.
Falls Church, VirginiaAges 18 years+ - NCT04347655Recruiting
Studies blood flow and heart pumping in adults with heart failure
This study looks at how well blood moves through the body and how strongly the left side of the heart pumps in adults. It compares people who have heart failure to people who do not, to better understand differences and possible causes.
Calgary, AlbertaAges 18 years+ - NCT04323371Recruiting
Study testing for heart-shock to reduce future events
This trial studies how to identify different types of “cardiogenic shock,” a serious drop in heart blood flow. It aims to use detailed patient information to guide care and possibly lower the chance of dangerous outcomes.
MilanAges 18–74 - NCT04278404Recruiting
Drug safety study for children already on certain medicines
This study measures how certain medicines move through the body and checks their safety in children. It may help doctors better understand dosing and side effects in kids who are already receiving these treatments, or in some kids who recently tested positive for COVID-19.
Phoenix, ArizonaAges birth–20 years - NCT00733590Recruiting
Study after ICD generator replacement for heart attack patients
This study follows people who had a prior heart attack and later received a replacement ICD (a device that helps prevent sudden dangerous heart rhythms). It is observational, meaning it mainly looks at outcomes and device-related information rather than testing a new drug.
Washington D.C., District of ColumbiaAges 18–85 - NCT03895541Recruiting
Heart ultrasound stiffness test for elderly diastolic heart failure
This trial tests a new heart ultrasound method to measure stiffness in the heart muscle, which could help doctors diagnose a type of heart failure where the heart is stiff but still squeezes normally. It is for elderly patients with heart failure, and the findings might lead to a simpler and safer way to identify this condition.
ParisAges 18–100 - NCT03836482Recruiting
SCD test for people with heart and kidney failure awaiting LVAD
This study looks at whether a treatment called SCD is safe and workable in people who have worsening heart failure along with kidney problems, and who are waiting to get an LVAD (a mechanical heart pump). It is mainly a feasibility study, meaning the researchers want to see if this approach can be used in real hospital care and monitor effects on key health measures.
Ann Arbor, MichiganAges 18 years+ - NCT03876223Recruiting
Testing imaging to study heart symptoms without blocked arteries
This trial studies people who have heart-related symptoms but do not have clear blocked heart arteries, using special heart imaging. It may help researchers better understand early forms of heart weakness (with preserved pumping function) and improve how these conditions are diagnosed.
Los Angeles, CaliforniaAges 18 years+ - NCT03854071Recruiting
Heart and health MRI testing in healthy people or patients
This study uses MRI (a scanning test) to develop new ways to measure heart function in both healthy volunteers and people with suspected or known heart disease. It may help researchers create better heart tests that could improve future diagnosis and monitoring.
Sheffield, EnglandAges 20–80 - NCT03549754Recruiting
iCaReMe registry for adults with diabetes, blood pressure, or heart/kidney disease
This is a health “registry,” meaning it collects information about people living with common chronic conditions. It may help researchers better understand real-world health needs and outcomes for people with type 2 diabetes, high blood pressure, heart failure, and/or chronic kidney disease.
Fortaleza, CearáAges 18 years+ - NCT03524222Recruiting
Home hospital care for adults after sudden illness
This trial tests whether certain adults can safely receive hospital-level care at home instead of staying in the hospital, using a home care team. It may help you recover in your own home if your condition fits their plan and you have support at home.
Boston, MassachusettsAges 18 years+ - NCT03238690Recruiting
LVAD conditioning to help your heart recover
This study looks at an approach called “conditioning” using your LVAD (a heart pump) while you wait for a transplant. It aims to see whether your heart muscle may recover better during planned changes in support.
Salt Lake City, UtahAges 18 years+ - NCT02966665RecruitingPhase 1
Testing blood vessel function in people of different health conditions
This early study measures how well your blood vessels work using tests that may include MRI. It compares healthy people with people who have conditions like COPD, pulmonary arterial hypertension, heart failure, or high blood pressure, to better understand “vascular function” in health and disease.
Salt Lake City, UtahAges 18 years+ - NCT02683681Enrolling by invitation
Create a heart tissue and blood sample registry
This study collects blood and/or heart tissue samples from certain people getting heart procedures or with a long-term heart pump. The goal is to store these samples for future research that may improve care for heart failure.
Ages 18 years+ - NCT02610426Recruiting
Genetic testing to study who develops heart failure during breast cancer therapy
This study uses DNA genetic testing to find DNA changes that might explain why some people develop heart failure (CHF) after breast cancer treatment with certain medicines. It may help researchers understand risk and improve care for future patients.
Boston, MassachusettsAges Any age - NCT02306200Recruiting
A study to improve heart and aorta health
This trial looks at ways to improve cardiovascular (heart and blood vessel) health, especially conditions that affect the aorta, such as aneurysms, or vascular problems that may run in families. If you have an aortic-related or other cardiovascular diagnosis (or you’re a healthy comparison participant), you may be invited to take part in this health-improvement program.
Ann Arbor, MichiganAges Any age - NCT01790152Recruiting
Dexrazoxane study to monitor heart damage in cancer survivors
This study tests dexrazoxane (DRZ) to see how it affects blood and heart-related “biomarkers,” or measurable signs of heart damage, after cancer treatment. It mainly targets survivors who may be at risk for cardiomyopathy (heart muscle weakness) or related heart failure.
Birmingham, AlabamaAges Any age - NCT00271180Recruiting
Tracks long-term performance of Medtronic heart devices
This study follows how well certain Medtronic heart devices work over the long term. You may be included if you have a qualifying Medtronic implant and the research team can reliably get your implant and follow-up information.
Birmingham, AlabamaAges Any age
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Common questions
- Are there clinical trials for heart failure?
- Yes. Clin2 currently lists 949 recruiting heart failure studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a heart failure trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a heart failure trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.