Clinical trials
Heart failure clinical trials
A condition where the heart can’t pump blood as well as it should. We’re tracking 981 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06331208Recruiting
Mechanisms of Lung Blood Vessel Problems in Heart Failure
This study looks at how heart failure affects blood vessels in the lungs. If you have heart failure with reduced pumping ability and need a heart catheterization, you may be able to join.
PragueAges 18 years+ - NCT06348498RecruitingPhase 1
Jia Shen tablets for chronic heart failure study
This trial tests a Chinese herbal tablet, Jia Shen, to see how the body processes it and if it helps people with chronic heart failure. It is for adults with weak heart pumping and stable medication use.
Tianjin, Tianjin MunicipalityAges 18–75 - NCT06349941RecruitingPhase 3
Heart failure rehab from home using video visits
This study tests whether a home-based cardiac rehab program using video visits and a smartphone app can help people with heart failure recover and feel better. It may be a good option if you have been hospitalized for heart failure recently and want to take part in rehab from home.
Dallas, TexasAges 18 years+ - NCT06381427Recruiting
Improving care for older heart patients before surgery
This trial studies whether special care planning before non-cardiac surgery can improve outcomes for older adults with signs of heart stress. If you are 65 or older and scheduled for a moderate- to high-risk surgery, you may be able to join.
GiessenAges 65 years+ - NCT06397833Recruiting
Monitoring heart pressure after heart failure hospitalization
This study is testing a new wearable device (Acorai ICPM) that measures pressure inside your heart. The goal is to see if it can help predict how well you will do after being discharged from the hospital for heart failure.
Uxbridge, MiddlesexAges 18 years+ - NCT06400927Recruiting
AI virtual assistant for managing new heart failure
This trial is testing a smartphone-based virtual assistant that uses artificial intelligence to help manage heart failure after you leave the hospital. It is designed for people who are newly diagnosed with heart failure and have moderate symptoms, to see if the AI assistant can help keep them healthy and out of the hospital.
Stevenage, HertfordshireAges 18 years+ - NCT06423599RecruitingPhase 2/Phase 3
Weight Loss for Obesity and Heart Failure
This study tests whether weight loss from a medication can improve how you feel, move, and how well your heart works. It's for people who have both obesity and heart failure with reduced pumping strength.
CopenhagenAges 18 years+ - NCT06424288RecruitingPhase 3
Testing vicadrostat plus empagliflozin for heart failure
This study tests whether adding a new study drug called vicadrostat to the standard heart failure medicine empagliflozin helps people with heart failure. It may be a good option if you have heart failure with preserved pumping function and are not already on a medicine called an MRA.
Mobile, AlabamaAges 18 years+ - NCT06444321Recruiting
Integrated care for frail patients with heart failure
This trial tests a special care program for people with both frailty (being weak or vulnerable) and heart failure (when the heart doesn't pump well). The program brings together different types of support to help you manage your health better after a hospital stay.
Drammen, AkershusAges 18 years+ - NCT06455878Recruiting
Mobile app for weight loss in heart failure patients
This trial tests a mobile app that helps you track your diet to manage your weight. It is designed for people with heart failure who are overweight and have recently been in the hospital for their condition.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06473532Recruiting
Text messages to improve heart failure self-care
This study tests whether helpful text messages can improve self-care for older adults with heart failure. If you join, you will receive tailored texts designed to support your heart health routine.
Chicago, IllinoisAges 50 years+ - NCT06479876Recruiting
Home-based heart rehab for heart failure
This study tests a home-based cardiac rehabilitation program for people with heart failure. It aims to help you become more active and manage your condition safely at home.
Nashville, TennesseeAges 18 years+ - NCT06515366Recruiting
Blood pressure and death risk in heart failure patients
This study looks at whether average blood pressure (MAP) is linked to survival in people with heart failure. If you are an adult with heart failure symptoms, participating may help doctors better understand how blood pressure affects outcomes.
Ankara, YenimahalleAges 18 years+ - NCT06516562Recruiting
Heart failure study in Vietnam: following patients' health over time
This study follows people with heart failure in Vietnam to understand their health and treatment over time. It does not test a new drug—just collects information to improve care.
Ho Chi Minh CityAges 18 years+ - NCT06517186Recruiting
Heart failure study with preserved pumping function
This study looks at how the heart muscle works in people with a type of heart failure where the heart pumps normally but doesn't fill properly. It aims to understand the cause better, which could lead to new treatments.
Chicago, IllinoisAges 30 years+ - NCT06526195Recruiting
A study of CardioMEMS and HeartMate 3 for advanced heart failure
This trial tests if a combination of a tiny lung-artery pressure sensor (CardioMEMS) and a mechanical heart pump (HeartMate 3) is safe and effective for people with advanced heart failure. If you qualify, you'll either get the heart pump plus standard medical therapy, or continue with standard therapy alone and have your pressure monitored remotely.
Phoenix, ArizonaAges 18 years+ - NCT06532825Recruiting
Nerve function test in advanced heart failure
This study looks at how the nervous system controls the heart in people with advanced heart failure. It may help doctors understand which patients are unlikely to recover, so they can plan the best care.
FrederiksbergAges 18 years+ - NCT06542822Recruiting
IV iron for non-ischemic heart failure with low iron
This study tests whether intravenous iron can improve outcomes for people with non-ischemic heart failure and low ejection fraction who are also iron deficient. If you fit the criteria, you may receive iron infusions to see if it helps your heart function and symptoms.
Southampton, HampshireAges 18 years+ - NCT06556485Recruiting
Early ablation for heart failure patients with heart pumps or on transplant list
This trial tests whether doing a catheter ablation early (before dangerous heart rhythms start) can help people with severe heart failure who need a heart transplant or already have an ICD. The goal is to see if this can improve outcomes.
Bad OeynhausenAges 18–99 - NCT06566911Recruiting
Voice analysis for monitoring heart failure
This trial tests if recording your voice can help doctors monitor heart failure that has suddenly gotten worse. You participate by giving voice samples, which may help find new ways to track your condition.
Rochester, MinnesotaAges 18 years+ - NCT06573892Recruiting
Gut Bacteria and Chronic Heart Failure
This study looks at how the bacteria in your gut (the microbiome) relates to chronic heart failure. Researchers want to see if certain probiotics (friendly bacteria) might help people with heart failure feel better.
AstanaAges 18 years+ - NCT06576752Recruiting
Home heart failure management after hospital discharge
This trial tests a program to manage heart failure at home after you leave the hospital. It aims to safely adjust your medications to optimal doses while you recover at home.
Lørenskog, AkershusAges 18 years+ - NCT06578520RecruitingPhase 4
Testing dapagliflozin for heart failure on dialysis
This trial tests whether adding dapagliflozin (a medication that helps protect the heart and kidneys) helps people with heart failure who are also on peritoneal dialysis. It may offer extra support for your heart and kidney health.
ValenciaAges 18 years+ - NCT06593223Recruiting
Noninvasive heart sound test for heart failure congestion
This trial tests a new, noninvasive device that uses low-frequency heart sounds to check for fluid buildup (congestion) in people with heart failure. It may help doctors monitor your condition without needles or surgery.
Shenzhen, GuangdongAges 18 years+
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Common questions
- Are there clinical trials for heart failure?
- Yes. Clin2 currently lists 981 recruiting heart failure studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a heart failure trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a heart failure trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.