Clinical trials
Heart failure clinical trials
A condition where the heart can’t pump blood as well as it should. We’re tracking 949 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07263035RecruitingPhase 4
Urine sodium-guided diuretic strategy for heart failure
This trial tests a new way to adjust diuretic (water pill) doses based on urine sodium levels in patients hospitalized for worsening heart failure. The goal is to improve fluid removal and get patients home sooner.
Lakeland, FloridaAges 18 years+ - NCT06758128Recruiting
Genes and immunity in worsening heart failure
This study looks at how your genes and immune system affect heart failure. Researchers want to understand why some people have flare-ups (exacerbations) and how the body responds.
San Giovanni Rotondo, FoggiaAges 18 years+ - NCT07252531Recruiting
BrioVAD heart pump study for advanced heart failure
This trial tests a new heart pump (BrioVAD) for people with very advanced heart failure. It aims to help those who are not getting better with standard treatments or who need extra support like IV medicines or a balloon pump.
RotterdamAges 18 years+ - NCT07253909Enrolling by invitation
Arm function in heart failure with ICD or CRT devices
This study looks at how well people with heart failure and certain heart devices (ICD or CRT) can use their arms and hands. It aims to understand if these devices affect upper body function.
Ankara, SamanpazarıAges 18 years+ - NCT07252310Enrolling by invitationPhase 4
Smartphone app to find best beta blocker dose for heart failure
This study uses a smartphone app to test how different beta blocker doses work best for you. It's for older adults with stable heart failure who want to fine-tune their treatment.
New York, New YorkAges 65 years+ - NCT07251894Enrolling by invitation
Meals after heart failure hospitalization
This study provides medically tailored meals to people recently hospitalized with heart failure to see if they help recovery. It is testing whether having healthy meals delivered can improve how patients feel and reduce the chance of being readmitted to the hospital.
Philadelphia, PennsylvaniaAges 18 years+ - NCT07247032Recruiting
Heart failure management with remote monitoring
This trial tests whether remote monitoring of your implanted heart device can help your doctors better manage your heart failure. It is for people with certain types of pacemakers or defibrillators who are willing to share their device data remotely.
ParisAges 18–85 - NCT07243119Enrolling by invitationPhase 4
Heart failure study with adenosine scans to predict recovery
This trial tests whether high-dose adenosine during a heart scan can better predict how well your heart muscle might recover, compared to standard dosing. The information could help doctors personalize treatment for people newly diagnosed with heart failure and a low ejection fraction.
HerningAges 18–100 - NCT07232030Recruiting
Barostim device for heart failure treatment
This trial tests a device called Barostim, which is implanted under the skin to stimulate nerves that help control heart failure. It's for people with mild to moderate heart failure whose symptoms are not fully controlled by medications.
Mobile, AlabamaAges 18 years+ - NCT07222813Recruiting
Liver scan to detect high blood pressure in the heart
This trial uses a special liver scan (FibroScan) to measure liver stiffness, which may help detect high pressure in the central veins returning blood to the heart. It is for people with heart failure who are already scheduled for a right heart catheterization.
Los Angeles, CaliforniaAges 18 years+ - NCT06397833Recruiting
Monitoring heart pressure after heart failure hospitalization
This study is testing a new wearable device (Acorai ICPM) that measures pressure inside your heart. The goal is to see if it can help predict how well you will do after being discharged from the hospital for heart failure.
Uxbridge, MiddlesexAges 18 years+ - NCT07214376Recruiting
Nerve ablation for pulmonary hypertension from left heart disease
This trial tests a device that uses a catheter to deliver energy to nerves around the pulmonary arteries, aiming to reduce high blood pressure in the lungs caused by left heart failure. It is for people with ongoing heart failure symptoms despite optimal medications.
Tucson, ArizonaAges 18–85 - NCT07218627RecruitingPhase 1
Study of an investigational medicine for heart failure
This study tests an experimental medicine called NNC0537-1482 for people with heart failure. It aims to see if the medicine helps improve symptoms and heart function.
LondonAges 40–75 - NCT07219511RecruitingPhase 1
Safety study of VS-041 for heart failure with preserved pumping strength
This trial tests an investigational drug called VS-041 to see if it's safe and helps people with a type of heart failure where the heart pumps well but doesn't relax properly (HFpEF). It may be an option if you are 50 or older and have stable heart failure symptoms.
Little Rock, ArkansasAges 50 years+ - NCT06915584Recruiting
Drug management study for heart failure
This study looks at how medications are managed in people with heart failure, especially those who have been in the hospital recently for worsening symptoms. It aims to improve treatment strategies.
Rome, RMAges 18 years+ - NCT07209098Recruiting
Heart failure study testing CCM therapy
This study tests a therapy called Cardiac Contractility Modulation (CCM) for people with heart failure. It uses a device to help the heart pump more strongly, and researchers compare it to standard care using patient records.
Marlton, New JerseyAges 18 years+ - NCT07205120Recruiting
Fluid-guided heart failure treatment study
This trial tests a new way to manage fluid levels in people hospitalized for heart failure. It aims to help doctors adjust treatment to keep you from coming back to the hospital.
Cleveland, OhioAges 21 years+ - NCT07204834Enrolling by invitation
Physical activity program for heart failure
This study tests a home-based physical activity program for people with heart failure. The program is designed to be safe and easy to follow, using a smartphone app to guide you, and may help you feel stronger and more active.
GranadaAges 18 years+ - NCT07199088Recruiting
Comparing two medicines for fluid buildup in heart failure
This study tests whether adding acetazolamide or metolazone to standard treatment helps remove extra fluid better in people hospitalized for heart failure. It aims to find a safer and more effective option for managing fluid overload.
Chak Four Hundred Fifty-four, Punjab ProvinceAges 18 years+ - NCT06253104Recruiting
Tracking muscle changes in acute heart failure
This study measures how thigh muscles change in people hospitalized with severe heart failure. It aims to understand muscle loss during this condition and how it relates to recovery.
Boston, MassachusettsAges 18–100 - NCT06939985Recruiting
Heart health and metabolism registry for heart failure
This trial is a registry that will follow people with different types of chronic heart failure to better understand how heart health and metabolism are linked. It may help doctors improve care for future patients.
ShanghaiAges 18 years+ - NCT07185100Recruiting
Finding early heart failure in at-risk adults across Germany
This study uses heart MRI scans to find unrecognized heart failure in people who have risk factors like diabetes, kidney disease, high blood pressure, or obesity but haven't been diagnosed with heart failure yet. If you join, you will help researchers learn how common hidden heart failure is and take an important step for your own heart health.
BerlinAges 40–69 - NCT07192341Recruiting
Heart failure drug for people with artificial heart valves
This trial tests a drug called sacubitril/valsartan to see if it helps people who have both a prosthetic heart valve and heart failure with a weak heart pump. The goal is to improve heart function and symptoms.
Kafr ash Shaykh, KafrelsheikhAges 18 years+ - NCT06734065Recruiting
Heart failure monitoring with a non-invasive lung fluid sensor
This trial tests a new device that measures fluid in your lungs without needles or surgery. It may help your doctor manage heart failure better, especially if you've been in the hospital recently or have symptoms like shortness of breath.
FlenAges 18 years+
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Common questions
- Are there clinical trials for heart failure?
- Yes. Clin2 currently lists 949 recruiting heart failure studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a heart failure trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a heart failure trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.