Clinical trials
Heart failure clinical trials
A condition where the heart can’t pump blood as well as it should. We’re tracking 981 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06601465RecruitingPhase 2
Vericiguat for cognitive health in heart failure
This study tests whether the heart failure medication vericiguat can also improve thinking and memory in people with heart failure who have mild cognitive problems. It involves taking vericiguat pills and having brain scans to track changes.
Calgary, AlbertaAges 18 years+ - NCT06626685Recruiting
Clonal blood cells in heart failure
This study looks at whether changes in blood cells (called clonal hematopoiesis) are linked to heart failure. By testing your blood, researchers hope to learn more about how heart failure progresses and find new ways to treat it.
BergamoAges 18 years+ - NCT06628973Recruiting
Social activities for women with heart failure
This trial tests a social program to help women with heart failure better stick with their medications and feel healthier. You'll be connected to community activities and support tailored to your needs.
Montreal, QuebecAges 18 years+ - NCT06652763Recruiting
MRI scan for heart failure with normal pumping strength
This study uses a special MRI scan with a natural contrast agent (manganese) to look at how well the heart muscle works in people with heart failure who still have normal pumping strength. The goal is to learn more about why this type of heart failure happens.
LeicesterAges 18 years+ - NCT06661876Recruiting
Heart radiation therapy for heart failure
This trial tests if a low dose of radiation to the heart can help people with advanced heart failure feel better and improve heart function. It is for patients whose heart failure is stable but severe, and who are already on the best medications.
LeuvenAges 18 years+ - NCT06671015Recruiting
Comparing breathing support methods after a breathing tube is removed in people with heart failure
This study compares two types of breathing support—a high-flow nasal cannula and noninvasive ventilation—to see which one better prevents the need for re-inserting a breathing tube in people with systolic heart failure who are at high risk for breathing problems after the tube is removed.
New Haven, ConnecticutAges 18 years+ - NCT06675448Recruiting
Best practices for heart failure with leaky mitral valve
This trial compares two treatment approaches for people with heart failure and a leaky mitral valve (mitral regurgitation). It aims to find which strategy leads to better outcomes. You may be eligible if your heart function is reduced and you have symptoms despite standard treatments.
Falls Church, VirginiaAges 18–99 - NCT06694727RecruitingPhase 3
Nutritional supplements for heart failure
This trial tests whether nutritional supplements can improve outcomes for people with heart failure. It aims to find an easy-to-follow, practical way to help manage the condition.
HellerupAges 18 years+ - NCT06699056Recruiting
AI heart monitor study for ejection fraction
This study uses an AI-powered wearable monitor to check how well your heart pumps blood (ejection fraction) from a simple EKG recording. It may help doctors quickly assess heart function without extra tests.
Orange, CaliforniaAges 18 years+ - NCT06707220Recruiting
Türkiye heart failure registry
This trial is a heart failure registry that collects information from people with heart failure across Turkey. By joining, researchers can learn more about the condition and how to treat it better.
Ankara, AnkaraAges 18 years+ - NCT07687186RecruitingPhase 3
Qishen Yiqi pills for chronic heart failure
This trial tests whether Qishen Yiqi Dripping Pills, a Chinese herbal medicine, can help people with chronic heart failure caused by coronary heart disease. It is for adults who have been on stable heart failure treatment for at least two weeks.
Bozhou, AnhuiAges 18–80 - NCT06008197RecruitingPhase 3
A study of finerenone for hospitalized heart failure patients
This trial tests a medication called finerenone to see if it helps people hospitalized for heart failure live longer and have fewer heart-related problems. It may be an option for those with a certain type of heart failure where the heart's pumping strength is mildly reduced or normal.
Birmingham, AlabamaAges 18 years+ - NCT07560982Recruiting
Improving medication adherence in advanced heart failure
This study looks at whether patients with severe heart failure follow their prescribed medications as recommended by treatment guidelines. The researchers want to understand what helps or prevents patients from taking their medicines correctly, which could improve their heart function and symptoms.
BergamoAges 18–75 - NCT07688863Enrolling by invitation
Comparing breathing muscle training methods for heart failure
This trial compares two different types of breathing muscle training to see which works better for people with heart failure and weak breathing muscles. You may join if you have heart failure with reduced pumping ability and are stable overall.
Viña del Mar, ValparaisoAges 18 years+ - NCT07447908Recruiting
Understanding worsening heart failure after leaving the hospital
This study monitors heart failure patients after a hospital stay or urgent clinic visit to better understand the signs of worsening heart failure. It may help researchers find ways to predict and prevent future exacerbations.
Newmarket, OntarioAges 18 years+ - NCT06714409Recruiting
Ultrasound-guided fluid removal in hospitalized heart failure
This study tests whether using ultrasound-guided treatment to reduce fluid buildup in the body can help people hospitalized for worsening heart failure feel better faster. It's for adults admitted with heart failure and high BNP levels.
OsloAges 18 years+ - NCT06724653Recruiting
Reducing Heart Failure Meds After Heart Recovery Study
This trial tests whether it is safe to slowly reduce some heart failure medications for people whose heart function has improved to normal. It is for patients who once had a weak heart pump but now have recovered strength and are stable on multiple medicines.
Jeonju, Jeollabuk-doAges 18 years+ - NCT06734065Recruiting
Heart failure monitoring with a non-invasive lung fluid sensor
This trial tests a new device that measures fluid in your lungs without needles or surgery. It may help your doctor manage heart failure better, especially if you've been in the hospital recently or have symptoms like shortness of breath.
FlenAges 18 years+ - NCT06737679Recruiting
Body scan therapy for heart failure patients
This trial tests whether a guided body scan can help people with heart failure better recognize their body's internal signals. It may improve how you understand and manage your symptoms.
Milan, ItalyAges 18–75 - NCT06758128Recruiting
Genes and immunity in worsening heart failure
This study looks at how your genes and immune system affect heart failure. Researchers want to understand why some people have flare-ups (exacerbations) and how the body responds.
San Giovanni Rotondo, FoggiaAges 18 years+ - NCT06773611Recruiting
Heart failure and transplant registry study
This study is creating a registry to track and learn from people with advanced heart failure or who have had a heart transplant. By joining, you help researchers better understand these conditions and improve care.
BolognaAges 18 years+ - NCT06774014Recruiting
Heart failure and diabetes: cell study
This study looks at how cells talk to each other in people who have both diabetes and heart failure. It may help doctors understand these conditions better.
Leeds, West YorkshireAges 18 years+ - NCT06783335Recruiting
Cordella sensor for chronic heart failure
This trial studies a small sensor placed in the lung artery to help manage chronic heart failure. It compares patients who get the sensor to those who receive standard care, to see if the sensor improves outcomes.
Naperville, IllinoisAges 18 years+ - NCT06785506Recruiting
Personalized heart failure treatment using multiple biomarkers
This trial tests if using a combination of biomarkers can help personalize treatment for people with a specific type of heart failure called HFpEF (or heart failure with preserved ejection fraction). It aims to find better treatments based on your individual test results.
Alkmaar, North HollandAges 18 years+
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Common questions
- Are there clinical trials for heart failure?
- Yes. Clin2 currently lists 981 recruiting heart failure studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a heart failure trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a heart failure trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.