Clinical trials
Hypertensive Heart Disease clinical trials
Below are recruiting hypertensive heart disease clinical trials, each written for real people, not researchers. We’re tracking 245 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05904093RecruitingPhase 1
Check if increasing fostamatinib doses are safe in sickle cell
This Phase 1 study tests whether increasing doses of fostamatinib are safe and tolerated in adults with stable sickle cell disease. It may help researchers understand if the drug could be a future treatment option for people with stable sickle cell.
Bethesda, MarylandAges 18–65 - NCT05462574Recruiting
MRI study of heart fat in pulmonary arterial hypertension
This trial uses MRI (and an additional MRI measurement called MRS) to study fat in the right side of the heart in people with pulmonary arterial hypertension (PAH). It may help researchers understand what’s going on in PAH and how it relates to symptoms and exercise ability.
Nashville, TennesseeAges 18 years+ - NCT06922240RecruitingPhase 3
Stopping riociguat to see how the heart responds in CTEPH
This trial is for people with a type of long-term blood clot in the lungs (CTEPH) who have been taking riociguat for at least 12 weeks. It will see what happens when the medication is stopped, focusing on how the right side of the heart is doing.
Beijing, ChinaAges 18 years+ - NCT06283758Recruiting
Ultrasound treatment for kidney fat to lower blood pressure
This trial tests a new ultrasound treatment that targets the fat pad around your kidney to lower blood pressure. It might be an option if your blood pressure is still high despite medication and you meet the size requirements for the fat pad.
Nanjing, JiangsuAges 18–65 - NCT06646601Recruiting
Garden-based program for heart and stroke recovery
This trial tests a preventive program that uses a therapeutic garden to help people with heart or blood vessel conditions. It looks at whether patients find the program helpful and easy to take part in.
GapAges 18 years+ - NCT06947460RecruitingPhase 1/Phase 2
CAR-T cell therapy for resistant lupus, sclerosis, and Sjögren's lung disease
This trial tests a special immune cell therapy (CAR-T cells targeting CD19 and BCMA) for people with lupus nephritis, systemic sclerosis, or Sjögren's-related lung blood vessel disease that hasn't improved with usual treatments. The goal is to see if this one-time cell infusion can calm the overactive immune system and improve symptoms.
Beijing, China,BeijingAges 10–65 - NCT05156736Recruiting
Study of early heart artery disease in South Asians
This study looks at early buildup of plaque in heart arteries in young adults from Pakistan. It may help doctors understand why this happens earlier and guide better prevention and screening.
Karachi, SindhAges 35–65 - NCT05236348Recruiting
Testing an optical blood pressure monitor against standard checks
This trial checks whether an optical device can measure your blood pressure as accurately as the usual method used by clinicians. You may be asked to come for 9 visits and do brief exercises while measurements are taken.
LausanneAges 21–85 - NCT05960604Recruiting
Monitoring blood pressure during surgery to predict low blood pressure
This study tests special ways of analyzing blood-pressure recordings during major surgery to better understand why some people develop low blood pressure (hypotension). If you have high blood pressure and need invasive blood-pressure monitoring, your surgery team will use readings to study patterns that may help predict or prevent low blood pressure.
AnkaraAges 18 years+ - NCT06129240Recruiting
Study of a new inhaled treprostinil powder for PH-ILD
This study tests a new dry powder inhaled medicine called LIQ861 for people with pulmonary hypertension related to lung scarring (PH-ILD). If you are already taking an inhaled treprostinil treatment but need better control, this trial may help you switch to a potentially easier-to-use version.
Phoenix, ArizonaAges 18–80 - NCT07683585Recruiting
Comparing blood pressure drugs after heart stent placement
This trial compares two different combinations of blood pressure medicines to see which works better for people who have had a heart stent placed. It may help find the best treatment plan for controlling blood pressure after the procedure.
MoscowAges 50–70 - NCT06711822Recruiting
Shockwave catheter for calcified heart artery blockages
This study tests a new catheter device (ShockPulse-10) that uses shockwaves to crack calcium in heart arteries before placing a stent. It is designed for people with hard, calcified blockages that are difficult to treat with balloons alone.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06962488Recruiting
Personalized blood pressure care using genetic risk
This study uses your genetic information (a polygenic risk score) to guide personalized blood pressure management. It aims to help people with high blood pressure and overall poor heart health improve their levels through tailored advice.
Birmingham, AlabamaAges 18–55 - NCT00471250Recruiting
Donate lung samples to help future lung and airway research
This study collects lung fluid and tissue (and sometimes nasal or breath samples) to store for future research. It aims to understand lung and airway biology, and you may help by donating samples during a short procedure.
Bethesda, MarylandAges 5–100 - NCT07576894Recruiting
How the Heart Responds to Exercise in COPD Patients
This study looks at how the right side of your heart responds when you exercise, in people with COPD (a chronic lung condition). The goal is to understand this response better and potentially improve treatments.
Aurora, ColoradoAges 40 years+ - NCT06801886Enrolling by invitationPhase 3
Silymarin for better kidney transplant success
This trial tests if adding silymarin (a milk thistle extract) to standard anti-rejection medicines helps protect the new kidney from damage. It may improve how well the transplanted kidney works over time.
MartinAges Any age - NCT04098354Recruiting
Phone monitoring for high blood pressure in kidney disease
This study tests whether using a home blood pressure monitoring device and phone-based check-ins can help people with high blood pressure and chronic kidney disease manage their health better. You may be asked to record readings and send them regularly during the study.
Edmonton, AlbertAges 18 years+ - NCT06386185Recruiting
Using heart tests to better detect pulmonary hypertension
This trial uses data from standard heart tests to develop a better way to detect pulmonary hypertension, a condition of high blood pressure in the lungs. It aims to help doctors diagnose this condition earlier and more accurately.
Bath, BanesAges 18 years+ - NCT06038630RecruitingPhase 2
Xenon gas MRI study for lung and heart health
This study uses a special MRI scan (Xenon gas imaging) to look at how well your lungs and heart are working. It is for people with certain lung conditions, those getting blood transfusions or phlebotomy, or healthy volunteers.
Durham, North CarolinaAges 18 years+ - NCT06195059Recruiting
Heart ultrasound with contrast during exercise to study lungs
This study uses a special ultrasound (echocardiography) with a contrast dye to see how blood flows through your lungs during exercise. It aims to help doctors better understand why patients get short of breath during activity.
Rochester, MinnesotaAges 18 years+ - NCT06272578Recruiting
Heart and kidney health study for chronic disease patients
This study checks how heart and kidney health are related in people with kidney disease, diabetes, high blood pressure, or high cholesterol. It is a single visit with tests to see if certain heart problems are common in these conditions.
Wedding, State of BerlinAges 18 years+ - NCT06512935Recruiting
Ventilator study for preterm infants with lung recovery
This study tests a new way of setting the ventilator for preterm babies born before 34 weeks who are still on a breathing machine. It aims to improve lung healing and heart function by finding the best pressure settings. The results could help your baby breathe more comfortably.
Birmingham, AlabamaAges 1 week–4 weeks - NCT07245680RecruitingPhase 3
Testing two pills vs one for pulmonary hypertension with heart or metabolism issues
This trial compares starting with two oral medications versus one for people newly diagnosed with pulmonary arterial hypertension (PAH) who also have conditions like high blood pressure, diabetes, obesity, or heart disease. The goal is to see if a two-drug approach works better for patients with these additional health issues.
Le Kremlin-BicêtreAges 18 years+ - NCT07285655RecruitingPhase 3
Study of L606 for lung disease with high blood pressure in the lungs
This trial tests a new treatment called L606 for people who have both a type of lung disease (ILD) and high blood pressure in the lungs (PH). The goal is to see if it is safe and helps with exercise and breathing.
Scottsdale, ArizonaAges 18–80
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Common questions
- Are there clinical trials for hypertensive heart disease?
- Yes. Clin2 currently lists 245 recruiting hypertensive heart disease studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a hypertensive heart disease trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a hypertensive heart disease trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.