Clinical trials
Hypertensive Heart Disease clinical trials
Below are recruiting hypertensive heart disease clinical trials, each written for real people, not researchers. We’re tracking 246 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07475052Enrolling by invitation
Heart rate monitoring to predict biologic therapy response in IBD
This study tests whether a wearable heart rate monitor can help predict how well biologic medications work for people with Crohn's disease or ulcerative colitis. If you are starting infliximab or vedolizumab for the first time, you may be eligible.
Xi'an, ShaanxiAges 18–75 - NCT07466745Recruiting
New Pulmonary Valve Study for Kids Needing Replacement
This study tests a new type of replacement valve for children who need a new pulmonary valve (the valve between the heart and lungs). Researchers want to see if the valve works safely and well in real-world use.
Los Angeles, CaliforniaAges 1.5 years–16 years - NCT07336316Enrolling by invitation
Heart MRI study for early heart failure with preserved pump function
This trial uses advanced MRI scans to study early signs of heart failure in people whose heart pumps normally but who have risk factors like diabetes, high blood pressure, or obesity. It aims to improve detection and understanding of this condition.
Ages Any age - NCT07130994Recruiting
Testing a new less invasive mitral valve replacement (SATURN)
This trial tests a new, less invasive device called the SATURN system to replace a severely leaky mitral heart valve without open-heart surgery. It is for people who are too high-risk for traditional surgery and are willing to take blood thinners.
Los Angeles, CaliforniaAges 18 years+ - NCT06958120Recruiting
Comparing two pain blocks for children's heart surgery
This study compares two types of numbing injections given with ultrasound guidance to reduce pain after heart surgery in children. It may be an option for children having certain types of heart surgery through a chest incision.
CairoAges 6 months–4 years - NCT06490250Recruiting
Breathing vs. movement exercises for hypertrophic cardiomyopathy
This study compares two types of gentle exercises—breathing muscle training and a traditional Chinese movement practice called Baduanjin—to see which helps people with hypertrophic cardiomyopathy feel better and improve their daily life. If you have a thickened heart muscle but are stable and have mild symptoms, you may be able to join.
IstanbulAges 18 years+ - NCT06896773Enrolling by invitation
Training in low oxygen conditions and heart health
This study tests whether training in a room with less oxygen (like being at high altitude) changes heart health markers in male cyclists. It may help understand if this type of training is safe and effective.
Warsaw, Masovian VoivodeshipAges 20–40 - NCT06871293Recruiting
Long Covid recovery: rehab with coaching
This study tests a program of rehab exercises and memory/thinking activities, along with coaching messages, to help people with Long Covid feel better and function in daily life. You may qualify if you had Covid, have high blood pressure or diabetes, and still have symptoms like fatigue or trouble thinking for at least 4 weeks.
Bogotá, Bogotá DCAges 18–80 - NCT06854458Recruiting
Stress heart MRI for better diagnosis of heart artery disease
This study uses a special stress heart MRI to measure blood flow and find blockages in the arteries that supply your heart. It is for people with chest pain or abnormal EKG results who have risk factors for heart disease, to help doctors diagnose and treat coronary artery disease more accurately.
San Francisco, CaliforniaAges 35–85 - NCT06587204Recruiting
Digital study for heart health in Black and Hispanic adults
This study uses a smartphone app to help Black and non-White Hispanic adults with heart or blood sugar conditions. It aims to make research easier to join from home and understand why some groups don't participate.
Miami, FloridaAges 18 years+ - NCT06400004RecruitingPhase 3
Lumason infusion vs. bolus for better heart imaging
This trial compares two ways of giving Lumason (an ultrasound contrast agent) to improve images of the left ventricle in people whose initial heart ultrasound was unclear. It may help those with a 'suboptimal' view of the heart's pumping chamber.
West Hills, CaliforniaAges 18 years+ - NCT06194591Recruiting
Ultrasound treatment for high blood pressure with kidney disease
This trial tests a new ultrasound treatment on the kidney arteries to see if it can safely lower blood pressure in people with high blood pressure and chronic kidney disease. It may help avoid more invasive procedures.
Lausanne, Canton of VaudAges 18–82 - NCT05918211RecruitingPhase 3
Udenafil test during exercise for teens with Fontan circulation
This trial tests whether udenafil helps teens and young people with Fontan circulation do better on exercise and breathing-related measures over time. You’d need to be on blood-thinning medicine, and be able to complete exercise testing safely.
Phoenix, ArizonaAges 12–18 - NCT05489575Recruiting
CPAP machine for high blood pressure when lying down at night
This study tests whether using a CPAP breathing machine at night can lower high blood pressure that happens while you sleep. It targets people with nervous-system problems that affect blood pressure changes when standing.
Nashville, TennesseeAges 40–80 - NCT07290842Recruiting
Dietary nitrate for high blood pressure kidney injury
This study tests whether a natural substance found in leafy greens (dietary nitrate) can help protect the kidneys of people with high blood pressure and early kidney damage. It may offer a simple dietary way to slow kidney disease.
HerningAges 18–70 - NCT05688579Enrolling by invitationPhase 4
Testing an aldosterone-blocking medicine in hard-to-control hypertension
This trial studies whether a medicine that blocks aldosterone (called an MRA) can improve cardiovascular outcomes in people with high aldosterone levels and high blood pressure. You may be asked to take the study medicine and have blood pressure, heart, and lab tests monitored over time.
Ürümqi, XinjiangAges 30–75 - NCT06891911Recruiting
Free healthy groceries to help lower blood pressure
This study gives people with high blood pressure free healthy groceries for 4 weeks to see if eating better can lower their blood pressure. It might help you get your blood pressure into a healthier range.
Boston, MassachusettsAges 18 years+ - NCT07783802RecruitingPhase 2
Study of clazakizumab for adults with high inflammation and heart risk
This study tests whether clazakizumab can reduce the risk of heart attacks or strokes in people with high levels of inflammation (measured by a blood test called hsCRP) and conditions like heart disease, obesity, diabetes, high blood pressure, or kidney disease. If you qualify, you'll receive either the study drug or a placebo to see if it helps lower your risk.
Huntsville, AlabamaAges 18 years+ - NCT04715022RecruitingPhase 1/Phase 2
Vitamin C study for insulin resistance in obesity
This early-stage study tests whether vitamin C (and possibly how your body uses it) affects blood vessel function in people with obesity and insulin resistance. You may be asked to stop certain supplements before starting so researchers can measure the effect more clearly.
Kansas City, KansasAges 35–65 - NCT06823115Enrolling by invitation
Worldwide study of kidney injury in newborns
This study looks at how common acute kidney injury is in newborns in the intensive care unit. It helps doctors understand which babies are at risk and how to prevent kidney problems.
Birmingham, AlabamaAges birth–2 weeks - NCT06215378RecruitingPhase 3
Protamine Sulfate to Reverse Heparin After TAVI
This trial tests whether giving protamine sulfate after a TAVI procedure (aortic valve replacement through the leg) to reverse the blood thinner heparin is safe and effective. It may help reduce bleeding risk for patients.
Paris, Île-de-France RegionAges 18 years+ - NCT05937854RecruitingPhase 2
Tadalafil to help breathing in COPD with pulmonary hypertension
This Phase 2 study tests whether tadalafil can improve breathlessness in people with COPD and pulmonary hypertension (high blood pressure in the lungs). It may help you breathe more easily if your symptoms are driven by this specific lung circulation problem.
Aurora, ColoradoAges 35–89 - NCT04927429Recruiting
MRI study to improve heart imaging
This trial helps develop and fine-tune MRI scans that look at the heart and blood vessels. It may help people with heart-related symptoms or conditions by improving how MRI images are created and interpreted.
Washington D.C., District of ColumbiaAges 18–100 - NCT03630211RecruitingPhase 2
Study of stem cell transplant for systemic sclerosis in youth
This Phase 2 study tests whether an “autologous” stem cell transplant—using your own stem cells—can reduce systemic sclerosis disease activity. It is mainly for children, teens, and young adults whose disease did not improve despite standard medicines.
Pittsburgh, PennsylvaniaAges 8–60
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Common questions
- Are there clinical trials for hypertensive heart disease?
- Yes. Clin2 currently lists 246 recruiting hypertensive heart disease studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a hypertensive heart disease trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a hypertensive heart disease trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.