Clinical trials
Hypoxemic Respiratory Failure clinical trials
Below are recruiting hypoxemic respiratory failure clinical trials, each written for real people, not researchers. We’re tracking 44 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07334379RecruitingPhase 2
Tailored treatment for acute breathing problems
This trial tests whether using a blood test to measure inflammation (IL-6) can help doctors decide if you should get either dexamethasone or tocilizumab for COVID-19 or other acute breathing problems. The goal is to find the best treatment faster and reduce side effects.
Toronto, OntarioAges 18 years+ - NCT07203781Recruiting
Breathing machine settings and their effect on breathing effort
This study is testing how different settings on a breathing machine affect your breathing effort and drive. It may help doctors find the best ventilator settings for patients with severe low oxygen levels.
Nijmegen, GelderlandAges 18 years+ - NCT06757166Recruiting
Non-invasive respiratory support for COVID-19 breathing failure
This study tests if non-invasive breathing support (like a mask or high-flow oxygen) can help hospitalized patients with low oxygen levels due to COVID-19, without needing a breathing tube. It aims to see how well it works and what risks it may have.
Rotterdam, South HollandAges 18 years+ - NCT06819644RecruitingPhase 3
Adjusting oxygen therapy using a depth camera to measure lung volumes
This trial tests whether adjusting high flow oxygen therapy (which delivers warm, moist oxygen through the nose) based on a new, non-contact technology — a depth camera that measures lung volumes without touching you — can help improve breathing in people with low oxygen levels. It's for patients in respiratory distress who need oxygen but don't have chronic lung disease.
BrestAges 18 years+ - NCT06425354Recruiting
Can breathing machine energy predict lung inflammation?
This study looks at a new measure called 'mechanical power' (the energy from the breathing machine) to see if it can predict inflammation in the lungs and blood of patients with low oxygen levels. It may help doctors better understand how the breathing machine affects lung damage.
RomaAges 18 years+ - NCT07322133RecruitingPhase 4
Comparing two blood pressure medicines for newborns with lung hypertension
This trial compares two medicines (dopamine and norepinephrine) to see which works better for raising blood pressure in newborns who have both low blood pressure and high blood pressure in the lungs. Both medicines are given through a vein to help stabilize your baby's blood pressure.
Sacramento, CaliforniaAges Up to 4 weeks - NCT03758508Recruiting
Noninvasive breathing support versus high-flow oxygen for pneumonia
This study compares two ways to help breathing in adults with pneumonia who have low oxygen levels: a noninvasive breathing machine versus high-flow oxygen. It aims to see which option helps patients breathe better and avoid getting worse.
MilanAges 18 years+ - NCT04707729Recruiting
Checking when to intubate patients on nasal high-flow oxygen
This study looks at a scoring system (ROX Index) to help decide the best timing to place a breathing tube (intubate) for adults who are struggling to get enough oxygen while using nasal high-flow (NHF). The goal is to see if using this timing approach can improve care for acute lung failure in the ICU.
Chicago, IllinoisAges 18–120 - NCT06104956Recruiting
Weaning from high-flow oxygen therapy in the ICU
This trial is testing a way to safely reduce high-flow oxygen therapy for patients in the ICU who have low oxygen levels. It might help find the right time to stop this treatment.
BloisAges 18–90 - NCT06438198Recruiting
Early switch to assisted breathing for lung failure
This trial tests switching patients from full ventilator support to a more gentle, assisted breathing mode earlier than usual. It may help people with severe lung failure recover faster and avoid complications from prolonged deep sedation.
RotterdamAges 18 years+ - NCT06921655Recruiting
Using pressure and muscle measurement to avoid too much breathing help in the ICU
This study tests a new way to adjust the breathing machine settings for patients who are awake and breathing on their own but still need support. The goal is to avoid giving too much help, which can make the breathing muscles weak.
Trento, TrentoAges 18 years+ - NCT07615010RecruitingPhase 2
agenT-797 Plus Standard Care for Severe Pneumonia With Respiratory Failure
This trial tests whether adding an experimental drug called agenT-797 to standard pneumonia treatment helps patients in the ICU who have severe pneumonia and serious difficulty breathing (acute hypoxemic respiratory failure). The drug is designed to help the immune system fight severe infection.
San Francisco, CaliforniaAges 18 years+ - NCT05990101Recruiting
Awake prone positioning for low oxygen in the ICU
This trial tests whether lying on your stomach (prone positioning) while awake can help you breathe better when you are in the ICU with low oxygen levels. It may reduce the need for a breathing tube.
KaunasAges 18 years+ - NCT06438302Recruiting
Nasal ventilation for patients on a breathing machine
This trial tests whether using a nasal ventilation mask affects how well the brain and lungs work in people who are already on a breathing machine. It is for patients with very low oxygen levels who have been intubated for less than 4 days.
ParisAges 18 years+ - NCT06829732Recruiting
Closed-loop oxygen control for ICU patients on a breathing machine
This trial tests a closed-loop system that automatically adjusts the oxygen level in your breathing tube, aiming to keep your oxygen levels in a safe range with less need for manual changes. It may help if you are in the ICU, need a breathing machine, and have low blood oxygen despite receiving extra oxygen.
Sabadell, BarcelonaAges 18 years+ - NCT06066502RecruitingPhase 3
Precision ventilation for ARDS
This study tests whether a customized breathing machine approach ("precision ventilation") is better than usual care for patients with ARDS. The goal is to improve oxygen levels and recovery while avoiding lung damage.
Tucson, ArizonaAges 18 years+ - NCT05462600Enrolling by invitation
Breathing monitoring test in non-smokers
This study measures how you breathe and how well oxygen and carbon dioxide move in and out of your lungs. It’s mainly a monitoring study to help researchers understand breathing patterns during a breathing test.
La Jolla, CaliforniaAges 18 years+ - NCT05562505Recruiting
Using ECMO to help you breathe, sit up, and come off a ventilator
This trial tests whether a heart-lung machine called venovenous ECMO can help people with severe breathing failure get less sedated, get extubated (have the breathing tube removed), and start moving. It’s for certain adults who are on a ventilator for a short time and have specific oxygenation problems.
Darlinghurst, New South WalesAges 18–65 - NCT06042621Enrolling by invitation
Improving communication in the ICU for patients, families, and staff
This study looks at how doctors, nurses, and other healthcare team members talk with patients and their families in the intensive care unit (ICU). It aims to improve understanding and support for everyone involved.
Chicago, IllinoisAges 18 years+ - NCT07363902Recruiting
Electrical muscle stimulation study for breathing support
This study tests a new device that uses mild electrical pulses to strengthen the muscles used for breathing in people who are on a ventilator. It aims to help them recover faster.
Barcelona, BarcelonaAges 18 years+
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Common questions
- Are there clinical trials for hypoxemic respiratory failure?
- Yes. Clin2 currently lists 44 recruiting hypoxemic respiratory failure studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a hypoxemic respiratory failure trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a hypoxemic respiratory failure trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.