Clinical trials · California
Infections clinical trials in California
We’re tracking 156 recruiting infections studies with a site in California — including Phase 1, Phase 1/Phase 2, Phase 2, Phase 3 and Phase 4 studies, each written for real people, not researchers.
Recruiting studies in California
- NCT06925321RecruitingPhase 3
Testing Fosmanogepix for Serious Mold Infections
This trial tests a new drug, Fosmanogepix, for treating serious mold infections that are hard to treat with current medicines. It may be an option for people with limited treatment choices.
Los Angeles, CaliforniaAges 18 years+ - NCT06859424RecruitingPhase 2
Testing a new GVHD prevention method after donor stem cell transplant
This trial tests a new way to prevent graft-versus-host disease (a common side effect of stem cell transplant) using a drug called cyclophosphamide after transplant. It is for adults with certain blood cancers who need a transplant from a partially matched unrelated donor.
Palo Alto, CaliforniaAges 18–66 - NCT06856174RecruitingPhase 4
Menopause Hormone Therapy for Women with HIV
This trial tests whether hormone therapy can help manage hot flashes and night sweats in women living with HIV who are going through menopause. It's designed to see if this treatment is safe and effective for this group.
Los Angeles, CaliforniaAges 40–60 - NCT06822426RecruitingPhase 3
Catheter lock solution to prevent bloodstream infections in patients on IV nutrition
This study tests a catheter lock solution called DefenCath (taurolidine and heparin) against a standard heparin lock to see if it reduces central line bloodstream infections in people receiving IV nutrition (total parenteral nutrition) for more than 3 months.
Los Angeles, CaliforniaAges 12 years+ - NCT06817889RecruitingPhase 2
Remdesivir for RSV in people with weak immune systems
This trial tests if remdesivir can safely treat RSV (a respiratory virus) in people with weakened immune systems, such as those who have had a stem cell or bone marrow transplant, CAR T-cell therapy, or are being treated for blood cancer. If you have a confirmed RSV infection in your nose or throat and are at moderate or high risk for complications, you may be able to join.
Duarte, CaliforniaAges 18 years+ - NCT06794541RecruitingPhase 2
Testing eravacycline for kids with serious belly infections
This trial tests an antibiotic called eravacycline for children (ages 8–17) with serious belly infections. The medicine is given through an IV in the hospital to see if it is safe and tolerable.
Los Angeles, CaliforniaAges 8–17 - NCT06801223RecruitingPhase 1
Testing sulbactam-durlobactam for children with ABC infection
This trial tests a new combination of antibiotics (sulbactam-durlobactam) for children with a serious infection caused by Acinetobacter bacteria. The goal is to see if this treatment is safe and works well for kids.
Los Angeles, CaliforniaAges 1 day–18 years - NCT06746883Recruiting
Safety study of an antibiotic for ABC infection
This study checks how safe sulbactam-durlobactam (a combination antibiotic) is in adults with a serious infection caused by ABC bacteria, especially looking for allergic reactions. If you are already getting this antibiotic as part of your care, you may be able to join.
Sacramento, CaliforniaAges 18 years+ - NCT06738407RecruitingPhase 4
Doxycycline to prevent STIs in high-risk people
This study tests whether taking a daily antibiotic (doxycycline) can prevent sexually transmitted infections in people at high risk. If you've had an STI recently and sometimes have sex without condoms, you might be able to join.
Los Angeles, CaliforniaAges 13–29 - NCT06714864RecruitingPhase 4
Preventing catheter infections in children on dialysis
This study tests a liquid that is put into the dialysis catheter after each session to prevent infections that can happen through the catheter. It is designed for children up to age 18 who need hemodialysis through a catheter.
Palo Alto, CaliforniaAges Up to 17 years - NCT03266653RecruitingPhase 2
T-cell therapy for stubborn Epstein-Barr virus after transplants
This trial tests an immune therapy made from EBV-targeted T-cells to treat EBV infections that do not improve with standard anti-viral medicines. It may help by strengthening the body’s ability to fight EBV after certain transplants or immune problems.
Los Angeles, CaliforniaAges 1 month–79 years - NCT06631287RecruitingPhase 3
Testing baricitinib for persistent long COVID symptoms
This trial tests whether the anti-inflammatory drug baricitinib can improve persistent long COVID symptoms like brain fog, fatigue, and shortness of breath. You may qualify if you had COVID-19 at least 6 months ago and still have bothersome symptoms that affect your daily life.
Los Angeles, CaliforniaAges 18 years+ - NCT06472765Enrolling by invitation
Study of the Vaginal Ecosystem in Healthy Women
This study looks at the natural balance of bacteria and other factors in the vagina of healthy women. It aims to learn more about what a healthy vaginal ecosystem looks like.
Fullerton, CaliforniaAges 18–89 - NCT06363877RecruitingPhase 3
Testing a germ-killing rinse during abdominal surgery
This trial is testing whether a diluted povidone-iodine (a common germ-killer) rinse inside the belly during surgery can prevent infections better than a plain saltwater rinse. It is for adults having abdominal surgery for certain types of wounds.
Loma Linda, CaliforniaAges 18–80 - NCT06262282Enrolling by invitation
Phage therapy for stubborn NTM infection in cystic fibrosis
This trial tests whether a special virus therapy (phage) can help clear stubborn NTM lung infections in people with cystic fibrosis who have been on antibiotics for over a year without success. Participants will continue their antibiotics while receiving the phages.
San Diego, CaliforniaAges 6 years+ - NCT06002607Recruiting
Shorter vs longer antibiotics for severe skin infections
This study compares a shorter course (about 7 days) of antibiotics to a longer course (about 14 days) for people who had surgery for a severe skin and muscle infection. The goal is to see if a shorter treatment works just as well.
Orange, CaliforniaAges 18 years+ - NCT05947071RecruitingPhase 2
Higher-dose flu vaccine versus standard dose in child transplant patients
This trial compares a higher-dose flu vaccine to the standard dose in children who recently received a kidney, heart, and/or liver transplant. It aims to see which dose better protects children against influenza while checking for safety.
Stanford, CaliforniaAges 3–17 - NCT05639647RecruitingPhase 2
Aztreonam plus avibactam for serious gram-negative infections
This trial compares two IV antibiotics (aztreonam and avibactam) against the best available treatment for serious gram-negative infections. It may help people who are hospitalized and need IV antibiotics, especially when the infection is caused by certain gram-negative bacteria.
San Diego, CaliforniaAges 9 months–17 years - NCT05624450RecruitingPhase 3
Test drug tozorakimab for hospitalized viral lung infection needing oxygen
This Phase 3 study tests tozorakimab to see if it helps people hospitalized with a viral lung infection that is causing low oxygen levels. You might qualify if you still need supplemental oxygen when the study starts.
Chula Vista, CaliforniaAges 18 years+ - NCT05592626RecruitingPhase 1/Phase 2
T cell activator STAR0602 for advanced solid tumors
This study tests an experimental drug called STAR0602 that aims to boost your immune system's T cells to fight advanced solid tumors. It's for patients whose cancer has not responded to standard treatments or for whom such treatments are not suitable.
Sacramento, CaliforniaAges 18 years+ - NCT05471908Recruiting
Compare automatic versus as-needed follow-up after common infections
This study compares two ways of scheduling a check-up after a child is hospitalized: an automatic visit or a visit only if needed (“as-needed”). It may help families and clinicians see which follow-up approach works best after illnesses like pneumonia, stomach flu (gastroenteritis), skin infections, or urinary tract infections.
Mountain View, CaliforniaAges Up to 18 years - NCT05586776RecruitingPhase 4
Using skin cleaning to prevent post-surgery wound infections
This trial tests a “skin decolonization” routine using medicated skin cleaning to help lower the risk of surgical site infections after abdominal surgery. You may be eligible if you recently had an open abdominal incision and your wound is healing as expected at discharge.
Sacramento, CaliforniaAges 18 years+ - NCT05369052RecruitingPhase 3
New antibiotic for moderate or severe diabetic foot infections
This Phase 3 trial tests a new medicine (contezolid acefosamil, and contezolid) to treat moderate or severe diabetic foot infections. It compares the new treatment to linezolid to see which works better and is safer for adults.
Corona, CaliforniaAges 18 years+ - NCT05361941Recruiting
Antibiotic graft to help bone regrow in infected knee surgery areas
This trial tests an antibiotic “graft” placed into or near infected bone cavities around a knee replacement (TKA) to help new bone grow. You may be considered if you have an infected knee implant area and can safely take part in follow-up visits and treatment.
Los Angeles, CaliforniaAges 22 years+
Infections trials by city in California
Where these studies are running in California
Institutions with a site for the recruiting infections studies listed above.
- City of Hope · 3 studies
- Stanford University · 3 studies
- Rady Children's Hospital · 2 studies
- UC Davis Health · 2 studies
- University of California, Irvine · 2 studies
- University of California, Los Angeles (UCLA) · 2 studies
- University of California, San Francisco · 2 studies
- 801 University of California, San Francisco HIV/AIDS CRS
What taking part in a infections study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Infections trials in other states
Common questions
- Are there infections clinical trials in California?
- Yes. We're currently tracking 156 recruiting infections studies with a site in California, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a infections study in California?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in California to take part?
- Not necessarily. These studies have a site in California, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a infections trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New infections studies open in California regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.