Clinical trials · Massachusetts
Infections clinical trials in Massachusetts
We’re tracking 60 recruiting infections studies with a site in Massachusetts — including Phase 1, Phase 1/Phase 2, Phase 2 and Phase 3 studies, each written for real people, not researchers.
Recruiting studies in Massachusetts
- NCT05361941Recruiting
Antibiotic graft to help bone regrow in infected knee surgery areas
This trial tests an antibiotic “graft” placed into or near infected bone cavities around a knee replacement (TKA) to help new bone grow. You may be considered if you have an infected knee implant area and can safely take part in follow-up visits and treatment.
Boston, MassachusettsAges 22 years+ - NCT03808922RecruitingPhase 3
DAS181 treatment for COVID-19 lung infection in immune-compromised adults
This Phase 3 trial tests DAS181 to treat lower lung (chest) viral infections in people with weakened immune systems, including a COVID-19 subgroup. It may help by targeting certain viruses in the lungs, but joining depends on your oxygen needs, recent diagnosis, and other safety factors.
Boston, MassachusettsAges Any age - NCT03562741Recruiting
Tracking outcomes of fecal transplant for repeated C. difficile
This study looks at how fecal microbiota transplantation (a transplant of healthy gut bacteria) works for people who get C. difficile infection repeatedly. It also focuses on collecting follow-up information to better understand which patients benefit and how.
Worcester, MassachusettsAges 16 years+ - NCT02545478Recruiting
Testing blood markers in people with and without infection
This study looks at blood test “markers” to tell the difference between infection and non-infectious illness. It may help doctors recognize infection earlier and avoid confusion with other conditions.
Boston, MassachusettsAges 18 years+ - NCT07719491RecruitingPhase 1
Study of GS-0415 in People with HIV
This study tests a new drug, GS-0415, for people with HIV. The study will see if this drug can help control the virus. Participants will continue taking their regular HIV medication.
Boston, MassachusettsAges 18–65 - NCT07665372Recruiting
Liver transplant from donors with HIV for people with HIV
This study tests whether giving people with HIV a liver from an HIV-positive donor is safe and works well. It looks at infections, cancer risks, and long-term health after transplant.
Boston, MassachusettsAges 18 years+ - NCT07473778Recruiting
Study of Lenacapavir for HIV Prevention
This trial tests a new medication, lenacapavir, to see how well it works for preventing HIV. It is for people who want or need PrEP (a medicine to prevent HIV) and are interested in learning about different options.
Boston, MassachusettsAges 18 years+ - NCT07391735Recruiting
Tracking Wound Healing After Surgery With an App
This study uses a smartphone app called MyHealthPal to track wound healing after certain spine or pain management surgeries. If you are getting a spinal cord stimulator or pain pump procedure, you may be able to join and help improve how recovery is monitored.
Chestnut Hill, MassachusettsAges 18 years+ - NCT07254208Enrolling by invitation
Long-term study for those who took PBGENE-HBV
This study follows people who have already received the experimental gene therapy PBGENE-HBV for hepatitis B. It aims to monitor long-term safety and health outcomes.
Boston, MassachusettsAges 19–80 - NCT07214571RecruitingPhase 2
Study of S-337395 for RSV in high-risk adults
This trial tests an experimental drug called S-337395 for adults with RSV who are not in the hospital but are at high risk for severe illness. It aims to see if the drug can help prevent symptoms from getting worse.
Worcester, MassachusettsAges 18 years+ - NCT07215273RecruitingPhase 2
Testing a new antifungal for mold infections in immunocompromised people
This study tests a new antifungal drug (EL219) compared to two standard treatments (liposomal amphotericin B or voriconazole) for people with weakened immune systems who have a suspected or confirmed mold infection. The goal is to see if the new drug works as well or better at treating the infection.
Boston, MassachusettsAges 18 years+ - NCT07013474RecruitingPhase 3
Study of ibuzatrelvir for immunocompromised adults with COVID-19
This trial tests an investigational medicine called ibuzatrelvir for adults with COVID-19 who have a weakened immune system. The study aims to see if it helps them recover and avoid severe illness.
Boston, MassachusettsAges 18 years+ - NCT06938867RecruitingPhase 1/Phase 2
Study of SNIPR001 for stem cell transplant patients
This trial tests an oral treatment called SNIPR001 that targets a type of E. coli bacteria resistant to common antibiotics. It may help prevent infections during stem cell transplant recovery.
Boston, MassachusettsAges 18 years+ - NCT06866405RecruitingPhase 3
RSV vaccine boost in a new pregnancy
This study tests whether a second dose of the RSV vaccine during a new pregnancy protects you and your baby from RSV. If you received the RSVpreF or Abrysvo vaccine in a past pregnancy, you may be able to join.
Boston, MassachusettsAges birth+ - NCT06853184RecruitingPhase 2
Artesunate for CMV in transplant patients
This trial tests a study drug called artesunate as a possible new treatment for CMV (a common virus) in people who have had a kidney, lung, heart, or liver transplant. It is for patients whose CMV infection requires treatment with standard antivirals like ganciclovir or valganciclovir.
Boston, MassachusettsAges 18 years+ - NCT06843902RecruitingPhase 2
Improving heart blood flow in women with HIV and diabetes or kidney problems
This trial tests a new approach to improve blood flow in the hearts of women with HIV who also have diabetes or kidney problems. It might help prevent heart disease in this population.
Boston, MassachusettsAges 45–75 - NCT05866952Recruiting
Breathing and blood-flow testing in long-COVID symptoms
This trial studies how the lungs’ breathing (airflow) and blood flow may be off in people with long-COVID symptoms like tiredness, shortness of breath, or trouble exercising. It may help researchers understand what’s driving symptoms and what kinds of abnormalities could be targeted.
Boston, MassachusettsAges 18–99 - NCT06679140RecruitingPhase 3
Study of Ibuzatrelvir for COVID-19 in high-risk patients
This trial tests if a new medicine called ibuzatrelvir can help people with COVID-19 who have certain health risks avoid severe illness. It is for patients who cannot or choose not to take another COVID-19 pill called Paxlovid.
Boston, MassachusettsAges 12 years+ - NCT06665646RecruitingPhase 1
HIV vaccine booster study for previous trial participants
This study tests a booster vaccine for HIV in people who were part of an earlier HIV vaccine trial. The goal is to see if it's safe and helps the immune system fight HIV better.
Boston, MassachusettsAges 18–60 - NCT06554717RecruitingPhase 2
Tesamorelin and exercise for physical function in HIV
This study tests whether adding tesamorelin to an exercise program helps older adults with HIV improve their physical function and reduce belly fat. It is designed for people who are mostly sedentary and show early signs of frailty.
Boston, MassachusettsAges 50–80 - NCT06399302Recruiting
Improving outcomes for lung transplant patients
This study looks at ways to improve outcomes for people who are waiting for or have recently received a lung transplant. It aims to find better management strategies for both donors and recipients.
Boston, MassachusettsAges 18 years+ - NCT06168019Recruiting
Flu and COVID-19 study for pregnant women in Nagpur
This study follows pregnant women in Nagpur to understand how influenza and COVID-19 affect them and their babies. Participants will be contacted twice a week for symptom checks and may provide blood samples at key points during pregnancy.
Boston, MassachusettsAges 18–50 - NCT06088277Recruiting
Texting to reduce HIV risk for dental patients
This study tests if daily text messages can help people lower their risk of getting HIV. You'll receive texts for a few months and complete surveys to see if the messages help.
Boston, MassachusettsAges 18 years+ - NCT06059391RecruitingPhase 2
Vaccine for stem cell donors to prevent CMV
This trial tests whether giving a CMV vaccine to stem cell donors can help protect recipients from CMV infection after transplant. It is for adults with specific blood cancers who are CMV-positive and have a matched related donor.
Boston, MassachusettsAges 18–75
Infections trials by city in Massachusetts
Where these studies are running in Massachusetts
Institutions with a site for the recruiting infections studies listed above.
- Massachusetts General Hospital · 7 studies
- Brigham and Women's Hospital · 5 studies
- Beth Israel Deaconess Medical Center · 2 studies
- Boston Medical Center · 2 studies
- University of Massachusetts Chan Medical School · 2 studies
- Boston University School of Public Health, Global Health
- Brigham & Womens Hospital
- Brigham and Women's Hospital Vaccine CRS (BWH VCRS)
What taking part in a infections study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Infections trials in other states
Common questions
- Are there infections clinical trials in Massachusetts?
- Yes. We're currently tracking 60 recruiting infections studies with a site in Massachusetts, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a infections study in Massachusetts?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in Massachusetts to take part?
- Not necessarily. These studies have a site in Massachusetts, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a infections trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New infections studies open in Massachusetts regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.