Clinical trials · Massachusetts
Infections clinical trials in Massachusetts
We’re tracking 63 recruiting infections studies with a site in Massachusetts — including Phase 1/Phase 2, Phase 2, Phase 3 and Phase 4 studies, each written for real people, not researchers.
Recruiting studies in Massachusetts
- NCT06859424RecruitingPhase 2
Testing a new GVHD prevention method after donor stem cell transplant
This trial tests a new way to prevent graft-versus-host disease (a common side effect of stem cell transplant) using a drug called cyclophosphamide after transplant. It is for adults with certain blood cancers who need a transplant from a partially matched unrelated donor.
Boston, MassachusettsAges 18–66 - NCT02545478Recruiting
Testing blood markers in people with and without infection
This study looks at blood test “markers” to tell the difference between infection and non-infectious illness. It may help doctors recognize infection earlier and avoid confusion with other conditions.
Boston, MassachusettsAges 18 years+ - NCT06636669Enrolling by invitationPhase 4
Probiotics to prevent repeat joint infection after replacement surgery
This trial tests whether taking probiotics can help prevent another infection in people who have had a hip or knee replacement that became infected. If you are scheduled for revision surgery due to an infection, this study may be a good fit.
Boston, MassachusettsAges 18–90 - NCT06262282Enrolling by invitation
Phage therapy for stubborn NTM infection in cystic fibrosis
This trial tests whether a special virus therapy (phage) can help clear stubborn NTM lung infections in people with cystic fibrosis who have been on antibiotics for over a year without success. Participants will continue their antibiotics while receiving the phages.
Boston, MassachusettsAges 6 years+ - NCT07214571RecruitingPhase 2
Study of S-337395 for RSV in high-risk adults
This trial tests an experimental drug called S-337395 for adults with RSV who are not in the hospital but are at high risk for severe illness. It aims to see if the drug can help prevent symptoms from getting worse.
Boston, MassachusettsAges 18 years+ - NCT07013474RecruitingPhase 3
Study of ibuzatrelvir for immunocompromised adults with COVID-19
This trial tests an investigational medicine called ibuzatrelvir for adults with COVID-19 who have a weakened immune system. The study aims to see if it helps them recover and avoid severe illness.
Boston, MassachusettsAges 18 years+ - NCT02140255RecruitingPhase 1/Phase 2
Intensive early HIV treatment in newborns to aim for remission
This study gives very early, intensive HIV medicine to infants diagnosed with HIV and follows them closely to see if HIV can go into remission (stop being detectable without ongoing treatment). It may help families understand whether treating right after birth can change a child’s long-term HIV outlook.
Boston, MassachusettsAges Up to 2 days - NCT04678154RecruitingPhase 3
Antibiotic trial for severe open fractures of the leg or foot
This trial tests a new way of giving antibiotics to people with severe open fractures in the leg, ankle, or foot. The goal is to see if it helps prevent infections after surgery.
Boston, MassachusettsAges 18–64 - NCT06071767RecruitingPhase 1/Phase 2
Immune therapy trial for early-treated HIV
This study tests whether a combination of three immune therapies can help control HIV without daily medication. You may qualify if you started HIV treatment very early and have had a suppressed viral load for at least a year.
Boston, MassachusettsAges 18 years+ - NCT07215273RecruitingPhase 2
Testing a new antifungal for mold infections in immunocompromised people
This study tests a new antifungal drug (EL219) compared to two standard treatments (liposomal amphotericin B or voriconazole) for people with weakened immune systems who have a suspected or confirmed mold infection. The goal is to see if the new drug works as well or better at treating the infection.
Boston, MassachusettsAges 18 years+ - NCT06679140RecruitingPhase 3
Study of Ibuzatrelvir for COVID-19 in high-risk patients
This trial tests if a new medicine called ibuzatrelvir can help people with COVID-19 who have certain health risks avoid severe illness. It is for patients who cannot or choose not to take another COVID-19 pill called Paxlovid.
Boston, MassachusettsAges 12 years+ - NCT07473778Recruiting
Study of Lenacapavir for HIV Prevention
This trial tests a new medication, lenacapavir, to see how well it works for preventing HIV. It is for people who want or need PrEP (a medicine to prevent HIV) and are interested in learning about different options.
Boston, MassachusettsAges 18 years+ - NCT03325855Recruiting
Fecal transplant registry for patients and donors
This study is a national “registry” that collects information from people who get fecal microbiota transplant (a stool-based treatment) and from people who donate stool. It helps researchers understand who receives these treatments and how they do over time.
Worcester, MassachusettsAges Any age - NCT03524222Recruiting
Home hospital care for adults after sudden illness
This trial tests whether certain adults can safely receive hospital-level care at home instead of staying in the hospital, using a home care team. It may help you recover in your own home if your condition fits their plan and you have support at home.
Boston, MassachusettsAges 18 years+ - NCT05389904Recruiting
Prevent C. difficile infection in high-risk hospital patients
This trial tests whether giving prevention right away can stop C. difficile infection from developing in people identified as high risk after a VRE swab. It may help reduce stomach infection and serious complications during hospital stay.
Boston, MassachusettsAges 18 years+ - NCT05488340RecruitingPhase 2
Study drug for hard-to-treat bladder infection in women
This Phase 2 trial tests LBP-EC01 to treat a bladder infection (UTI) caused by drug-resistant E. coli. It may help by targeting the specific bacteria that make UTIs harder to cure with common antibiotics.
Boston, MassachusettsAges 18–75 - NCT05817825Recruiting
Remote program to support recovery after opioid use
This study tests a new intensive outpatient program delivered by video or phone to help people with opioid use disorder (and other substance use disorders) stay on track after leaving the hospital. It may help by offering structured support while you are at home.
Boston, MassachusettsAges 18 years+ - NCT05866952Recruiting
Breathing and blood-flow testing in long-COVID symptoms
This trial studies how the lungs’ breathing (airflow) and blood flow may be off in people with long-COVID symptoms like tiredness, shortness of breath, or trouble exercising. It may help researchers understand what’s driving symptoms and what kinds of abnormalities could be targeted.
Boston, MassachusettsAges 18–99 - NCT05950607Recruiting
Nursing home study to reduce unnecessary antibiotic use
This study looks at ways to lower how often antibiotics are used in nursing home residents with Alzheimer’s disease and other dementias. It aims to make antibiotic use more appropriate while monitoring resident outcomes.
Boston, MassachusettsAges 60–106 - NCT05953233Recruiting
Air study in inner-city schools using home nasal swabs
This study looks at air in inner-city schools and how it may affect children’s health. You may be asked to collect nasal swab samples at home and answer questions, especially if your child’s classroom is part of the study.
Boston, MassachusettsAges 6–90 - NCT05973084Recruiting
COVID spread study in Malawi households and vaccine recipients
This study tracks how COVID-19 spreads and causes illness in real households in Blantyre, Malawi, and compares groups after infection or vaccination. If you qualify, you’ll do follow-up testing and visits for several months.
Boston, MassachusettsAges 5–75 - NCT05978141Recruiting
T-cell lymphoma registry study
This study creates a registry for people with certain T-cell or NK-cell lymphomas. It collects health information and tumor samples to learn more about these diseases and improve future treatments.
Boston, MassachusettsAges Any age - NCT06056297RecruitingPhase 3
Study of Mavorixafor for chronic neutropenia with infections
This trial tests if mavorixafor can help people with certain types of long-term low neutrophil counts (chronic neutropenia) who still get frequent or serious infections. It aims to reduce infection risk by boosting your body's infection-fighting cells.
Boston, MassachusettsAges 12 years+ - NCT06059391RecruitingPhase 2
Vaccine for stem cell donors to prevent CMV
This trial tests whether giving a CMV vaccine to stem cell donors can help protect recipients from CMV infection after transplant. It is for adults with specific blood cancers who are CMV-positive and have a matched related donor.
Boston, MassachusettsAges 18–75
Infections trials by city in Massachusetts
Where these studies are running in Massachusetts
Institutions with a site for the recruiting infections studies listed above.
- Brigham and Women's Hospital · 7 studies
- Massachusetts General Hospital · 5 studies
- Beth Israel Deaconess Medical Center · 2 studies
- Boston Children's Hospital · 2 studies
- Boston Medical Center · 2 studies
- Dana-Farber Cancer Institute · 2 studies
- University of Massachusetts Chan Medical School · 2 studies
- Boston Children's Cancer Center
What taking part in a infections study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Infections trials in other states
Common questions
- Are there infections clinical trials in Massachusetts?
- Yes. We're currently tracking 63 recruiting infections studies with a site in Massachusetts, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a infections study in Massachusetts?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in Massachusetts to take part?
- Not necessarily. These studies have a site in Massachusetts, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a infections trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New infections studies open in Massachusetts regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.