Clinical trials
Intensive Care (ICU) clinical trials
Below are recruiting intensive care (icu) clinical trials, each written for real people, not researchers. We’re tracking 205 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07761364Recruiting
Contact with family in the intensive care unit
This study looks at how a visit from your main family caregiver affects your body while you are in the intensive care unit (ICU). It aims to see if having that personal contact can help you feel better and recover.
Mexico City, Mexico CityAges 18–59 - NCT05279547Recruiting
Bed-cycle exercise study to test muscle oxygen during ICU care
This trial tests whether brief “interval” bed-cycling changes how well your leg muscles use oxygen compared with steady cycling. It’s meant for carefully selected ICU patients who can safely do active cycling while on ventilator support.
LeuvenAges 18 years+ - NCT05409573Recruiting
Check oxygen monitoring during pre-intubation in the ICU
This study tests whether a specific oxygen level monitor (end-tidal oxygen, or EtO2) can be used during “preoxygenation” before breathing tube placement. It may help clinicians intubate more safely for people who urgently need a breathing tube due to serious breathing failure.
OrléansAges 18 years+ - NCT05671614Recruiting
Prevent muscle stem cell failure after critical illness
This trial studies ways to improve recovery of skeletal muscle in people who have been very sick in the ICU. It focuses on preventing problems with the body’s muscle “repair cells” after critical illness.
Prague, Czech RepublicAges 18 years+ - NCT05814094Recruiting
Testing a red blood transfusion approach during ECMO
This study looks at whether giving red blood cell transfusions in a specific way is practical and safe for people receiving ECMO (a heart-lung support machine). It’s mainly a feasibility study, meaning the goal is to see if the plan can be carried out smoothly and safely.
Camperdown, New South WalesAges 18 years+ - NCT07075926Recruiting
Heart ultrasound to predict breathing tube removal success in ICU
This study uses a heart ultrasound to see if it can help doctors predict when patients in the ICU are ready to have their breathing tube removed. It may help avoid failed extubations and reduce complications.
Istanbul, IstanbulAges 18 years+ - NCT07073976Recruiting
Predicting success of coming off the breathing machine using heart ultrasound
This study uses an ultrasound of the heart (echocardiogram) to check how well the right side of your heart is working. The goal is to see if that can help predict whether you will successfully come off the breathing machine.
Istanbul, IstanbulAges 18 years+ - NCT06840756RecruitingPhase 4
Does donor-patient sex matching improve blood transfusion outcomes?
This trial tests whether giving ICU patients blood from a donor of the same sex (male-to-male or female-to-female) leads to better recovery compared to mismatched transfusions. The goal is to see if matching donor and patient sex makes a difference in how well patients do.
Hamilton, OntarioAges 18 years+ - NCT07188350Recruiting
Electrical muscle stimulation for patients on a breathing machine
This trial tests whether low-level electrical pulses to the leg muscles can help prevent weakness in patients who need a breathing tube (ventilator) for more than 48 hours. It aims to see if this treatment helps patients recover faster.
Porto Alegre, Rio Grande do SulAges 18 years+ - NCT07672106Recruiting
Predicting breathing tube need after major surgery recovery
This study watches patients after major surgery to see which factors may increase the chance of needing a breathing tube again. It helps doctors better predict and prevent breathing problems in the intensive care unit.
Istanbul, ŞişliAges 18 years+ - NCT07735182Recruiting
Gut bacteria and organ damage in sepsis
This study looks at how bacteria in your gut and other signs in your body affect liver and kidney damage in people with sepsis. It also compares findings to healthy volunteers to see what is different.
Hangzhou, ZhejiangAges 18 years+ - NCT07449416Recruiting
Ceribell Delirium Monitor Study in ICU Patients
This pilot study tests a special brain monitor (called Ceribell EEG) to see if it can help detect delirium in ICU patients. Delirium is a state of confusion that can happen during a serious illness, and this monitor may help doctors catch it early.
Irvine, CaliforniaAges 18 years+ - NCT07704710Enrolling by invitation
Changing Pulse Oximeter Probe Placement to Prevent Skin Injury in the ICU
This study looks at whether changing the position of the pulse oximeter clip on the finger every so often can help prevent skin injuries (like pressure sores) in ICU patients. It is for adults in intensive care who are deeply unconscious and will be there for several days.
AnkaraAges 18 years+ - NCT04176094Recruiting
Trial of ICU overnight resident scheduling plans
This study tests whether changing how ICU residents are scheduled for overnight shifts affects training and ICU operations. It looks at participating adult ICU patients and the residents and staff who work overnight during the study periods.
Toronto, OntarioAges 18 years+ - NCT04588311RecruitingPhase 3
Epoetin to improve outcomes in severe trauma ICU patients
This trial tests epoetin alfa (a blood-building medicine) to help reduce death and severe disability in critically ill trauma patients in the ICU. You may be considered if your ICU team expects a longer stay and the timing after injury is early.
Camperdown, New South WalesAges 18–75 - NCT05247502Recruiting
Study of kidney outcomes after ICU kidney injury
This study follows adults who stay in the ICU for more than 24 hours to see how an episode of acute kidney failure affects kidney health over the long term. Your participation helps researchers understand which ICU patients may need closer kidney monitoring later.
Clermont-FerrandAges 18 years+ - NCT05357170Recruiting
Testing gut bacteria changes after severe ICU illnesses
This study looks at changes in the microbiome (gut bacteria) in adults after serious ICU illnesses like sepsis, major trauma, or open heart/abdominal surgery. It may help researchers understand why recovery can be harder in some people and guide future treatments.
Gainesville, FloridaAges 18–110 - NCT05551325Recruiting
Resetting sleep timing for ICU patients to support recovery
This study tests a “sleep chronobundle,” a set of sleep and light-timing steps, to improve daily sleep-wake timing in people in the ICU on breathing or blood-pressure support. It also checks whether the body’s sleep rhythms are more aligned during critical illness and over time.
New Haven, ConnecticutAges 18 years+ - NCT05565222RecruitingPhase 3
Testing two antibiotics as alternatives for ICU severe ESBL infections
This study compares two antibiotics—piperacillin-tazobactam or temocillin—to treat severe ICU infections caused by certain hard-to-treat gut bacteria (ESBL). It may help patients avoid the use of carbapenem antibiotics like meropenem when the bacteria are susceptible.
ParisAges 18 years+ - NCT05660252Recruiting
Family conversations to reduce refusal of organ donation after ICU care
This study tests whether a structured, shared conversation between the clinical team and the patient’s family can reduce how often families refuse organ donation after life-sustaining treatment is stopped. If you are eligible, the trial may guide how consent discussions are handled during a difficult ICU decision.
Nantes, Pays de la Loire RegionAges 18 years+ - NCT05686850Recruiting
Noninvasive breathing support vs high-flow oxygen after ICU extubation
This study compares two breathing supports used after a breathing tube is removed in the ICU: a noninvasive ventilator (mask-based) versus high-flow nasal oxygen. It aims to see which one works better when patients develop breathing trouble soon after extubation.
BrusselsAges 18 years+ - NCT05696093RecruitingPhase 3
Cotrimoxazole for step-down treatment of ventilator pneumonia
This trial tests whether switching from an initial antibiotic to cotrimoxazole (a specific antibiotic combination) can work as well—or better—for ventilator-associated pneumonia in ICU patients. It aims to see if “de-escalating” antibiotics can control the infection while keeping vital signs stable.
AmiensAges 18 years+ - NCT05855252Recruiting
Study on monitoring and outcomes after moderate to severe head injury
This observational study follows adults with moderate to severe traumatic brain injury to understand care and outcomes. It collects information from the first 48 hours in the ICU and may help improve how clinicians monitor and treat patients in the critical early period.
Kogarah, New South WalesAges 18 years+ - NCT05860894Recruiting
Study of new ICU atrial fibrillation
This trial looks at people who develop a new irregular heart rhythm called atrial fibrillation while in the intensive care unit (ICU). It tests an approach to help with that condition after critical illness, aiming to improve outcomes for those affected.
BesançonAges 18 years+
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Common questions
- Are there clinical trials for intensive care (icu)?
- Yes. Clin2 currently lists 205 recruiting intensive care (icu) studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a intensive care (icu) trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a intensive care (icu) trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.