Clinical trials
Intensive Care (ICU) clinical trials
Below are recruiting intensive care (icu) clinical trials, each written for real people, not researchers. We’re tracking 198 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07075926Recruiting
Heart ultrasound to predict breathing tube removal success in ICU
This study uses a heart ultrasound to see if it can help doctors predict when patients in the ICU are ready to have their breathing tube removed. It may help avoid failed extubations and reduce complications.
Istanbul, IstanbulAges 18 years+ - NCT05696093RecruitingPhase 3
Cotrimoxazole for step-down treatment of ventilator pneumonia
This trial tests whether switching from an initial antibiotic to cotrimoxazole (a specific antibiotic combination) can work as well—or better—for ventilator-associated pneumonia in ICU patients. It aims to see if “de-escalating” antibiotics can control the infection while keeping vital signs stable.
AmiensAges 18 years+ - NCT07074028Recruiting
Tracking muscle changes in ICU patients with sepsis
This study is for people in the ICU with sepsis who need a breathing machine for a long time. It monitors muscle changes during recovery to understand how sepsis affects muscles.
Saint-BrieucAges 18 years+ - NCT07073976Recruiting
Predicting success of coming off the breathing machine using heart ultrasound
This study uses an ultrasound of the heart (echocardiogram) to check how well the right side of your heart is working. The goal is to see if that can help predict whether you will successfully come off the breathing machine.
Istanbul, IstanbulAges 18 years+ - NCT07032987Recruiting
Improving sedation with a new care plan for ICU patients
This trial tests a new sedation protocol for adults in intensive care who need strong pain relief or sedation medicines. It aims to make sedation safer and more comfortable, and includes people on ECMO (a heart-lung machine) or a ventilator (breathing machine) for severe breathing problems.
London, LondonAges 18–100 - NCT05814094Recruiting
Testing a red blood transfusion approach during ECMO
This study looks at whether giving red blood cell transfusions in a specific way is practical and safe for people receiving ECMO (a heart-lung support machine). It’s mainly a feasibility study, meaning the goal is to see if the plan can be carried out smoothly and safely.
Camperdown, New South WalesAges 18 years+ - NCT07013175Recruiting
Wise Choices in the Intensive Care Unit
This study looks at how decisions are made in the ICU. It may help improve care for adult patients in Swedish intensive care units.
StockholmAges 18 years+ - NCT06923462Recruiting
VoiceLove app for ICU patients on a ventilator
This study tests a special app called VoiceLove that helps patients in the ICU who are on a breathing machine communicate with their family and care team. The goal is to reduce confusion and improve connection and satisfaction for everyone involved.
Nashville, TennesseeAges 18 years+ - NCT06881927RecruitingPhase 4
Reducing anti-rejection meds in ICU for kidney transplant patients
This study tests whether quickly reducing your anti-rejection medicines during a life-threatening ICU stay can help your kidneys recover and improve your overall outcome. It is for kidney transplant recipients with septic shock or severe breathing failure.
StrasbourgAges 18 years+ - NCT06849570Recruiting
Tailoring breathing support and muscle relaxants during prone positioning for severe lung injury
This trial tests two ways to adjust ventilator settings for patients with severe lung injury whose oxygen levels are very low. It aims to find out the best level of breathing support and whether giving muscle relaxants during prone positioning helps improve oxygen levels.
Aix-en-ProvenceAges 18 years+ - NCT06840756RecruitingPhase 4
Does donor-patient sex matching improve blood transfusion outcomes?
This trial tests whether giving ICU patients blood from a donor of the same sex (male-to-male or female-to-female) leads to better recovery compared to mismatched transfusions. The goal is to see if matching donor and patient sex makes a difference in how well patients do.
Hamilton, OntarioAges 18 years+ - NCT06819592RecruitingPhase 3
Preventing early lung infections after severe brain injury
This study tests whether giving an antibiotic (ceftriaxone) early after a severe brain injury can prevent lung infections caused by the breathing machine (ventilator). It is for adults in the ICU who recently started on a ventilator due to a brain emergency.
Canberra, Australian Capital TerritoryAges 18 years+ - NCT04588311RecruitingPhase 3
Epoetin to improve outcomes in severe trauma ICU patients
This trial tests epoetin alfa (a blood-building medicine) to help reduce death and severe disability in critically ill trauma patients in the ICU. You may be considered if your ICU team expects a longer stay and the timing after injury is early.
Camperdown, New South WalesAges 18–75 - NCT06809868Recruiting
Study of genetic elements in sepsis and aging
This trial looks at how certain genetic elements may affect the immune system in older adults with sepsis. It aims to understand why older patients may respond differently to severe infections.
San Francisco, CaliforniaAges 18 years+ - NCT06411561Recruiting
Boosting memory after ICU stay for older adults
This study tests a combination of activities (like cognitive training and exercise) to help older adults recover thinking and memory after a serious illness in the ICU. It may help you regain sharpness and independence after leaving the intensive care unit.
Seattle, WashingtonAges 60 years+ - NCT06607055Recruiting
Immune markers in ICU patients with pneumonia
This study looks at how the immune system reacts in ICU patients on a ventilator who have pneumonia. By measuring immune markers, the researchers hope to better understand and predict complications like ventilator-associated pneumonia.
Aix-en-ProvenceAges 18 years+ - NCT06532994Recruiting
Prediction tool for recovery after critical illness
This study looks at how well people recover after critical illness. It tests a prediction tool to help guide rehabilitation for patients who needed a breathing machine and started rehab in the ICU.
Wuhan, HubeiAges 18–90 - NCT06296381Recruiting
Measuring normal muscle strength in ICU patients and healthy people
This study measures normal muscle strength in healthy people and ICU patients to create a reference guide. If you are healthy or in the ICU and can follow instructions, you may be able to help.
Recife, BrazilAges 18–90 - NCT06229288RecruitingPhase 3
Pneumonia treatment: amoxicillin alone vs. with clavulanate for adults 65+
This trial compares two antibiotics for older adults hospitalized with pneumonia. It aims to see if amoxicillin alone works as well as amoxicillin combined with clavulanate, which might reduce side effects.
Saint-Nazaire, FranceAges 65 years+ - NCT06100978Recruiting
Patient experiences after severe seizures
This study interviews people who had a severe, prolonged seizure (status epilepticus) and were treated in intensive care. It asks how they feel and what they experienced 3 months to 5 years later.
AngoulêmeAges 18 years+ - NCT05686850Recruiting
Noninvasive breathing support vs high-flow oxygen after ICU extubation
This study compares two breathing supports used after a breathing tube is removed in the ICU: a noninvasive ventilator (mask-based) versus high-flow nasal oxygen. It aims to see which one works better when patients develop breathing trouble soon after extubation.
BrusselsAges 18 years+ - NCT05551325Recruiting
Resetting sleep timing for ICU patients to support recovery
This study tests a “sleep chronobundle,” a set of sleep and light-timing steps, to improve daily sleep-wake timing in people in the ICU on breathing or blood-pressure support. It also checks whether the body’s sleep rhythms are more aligned during critical illness and over time.
New Haven, ConnecticutAges 18 years+ - NCT05409573Recruiting
Check oxygen monitoring during pre-intubation in the ICU
This study tests whether a specific oxygen level monitor (end-tidal oxygen, or EtO2) can be used during “preoxygenation” before breathing tube placement. It may help clinicians intubate more safely for people who urgently need a breathing tube due to serious breathing failure.
OrléansAges 18 years+ - NCT05357170Recruiting
Testing gut bacteria changes after severe ICU illnesses
This study looks at changes in the microbiome (gut bacteria) in adults after serious ICU illnesses like sepsis, major trauma, or open heart/abdominal surgery. It may help researchers understand why recovery can be harder in some people and guide future treatments.
Gainesville, FloridaAges 18–110
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Common questions
- Are there clinical trials for intensive care (icu)?
- Yes. Clin2 currently lists 198 recruiting intensive care (icu) studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a intensive care (icu) trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a intensive care (icu) trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.