Clinical trials
Intensive Care clinical trials
Below are recruiting intensive care clinical trials, each written for real people, not researchers. We’re tracking 416 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05867472RecruitingPhase 3
Sedation plan for critically ill children on breathing machines
This Phase 3 trial tests a sedation approach using inhaled (“volatile”) anesthesia gases for children who need a ventilator. It aims to improve comfort and brain-related outcomes while they stay on the breathing machine for at least a day.
Hamilton, OntarioAges 1 month–18 years - NCT05804773Recruiting
Studying brain blood flow changes when blood pressure changes
This study looks at how blood flow in the brain changes when blood pressure rises or falls in people in the ICU. It may help doctors understand safer ways to manage blood pressure in critically ill patients.
Paris, FranceAges 18 years+ - NCT05686850Recruiting
Noninvasive breathing support vs high-flow oxygen after ICU extubation
This study compares two breathing supports used after a breathing tube is removed in the ICU: a noninvasive ventilator (mask-based) versus high-flow nasal oxygen. It aims to see which one works better when patients develop breathing trouble soon after extubation.
BrusselsAges 18 years+ - NCT05551325Recruiting
Resetting sleep timing for ICU patients to support recovery
This study tests a “sleep chronobundle,” a set of sleep and light-timing steps, to improve daily sleep-wake timing in people in the ICU on breathing or blood-pressure support. It also checks whether the body’s sleep rhythms are more aligned during critical illness and over time.
New Haven, ConnecticutAges 18 years+ - NCT05537298Recruiting
Help for muscle recovery after serious ICU illness
This trial looks at how to improve muscle strength and function after a stay in the ICU for sepsis or acute respiratory failure. If you recover from the illness but your muscles become weak, this study may test an approach to help rebuild strength faster.
Birmingham, AlabamaAges 18 years+ - NCT05409573Recruiting
Check oxygen monitoring during pre-intubation in the ICU
This study tests whether a specific oxygen level monitor (end-tidal oxygen, or EtO2) can be used during “preoxygenation” before breathing tube placement. It may help clinicians intubate more safely for people who urgently need a breathing tube due to serious breathing failure.
OrléansAges 18 years+ - NCT05357170Recruiting
Testing gut bacteria changes after severe ICU illnesses
This study looks at changes in the microbiome (gut bacteria) in adults after serious ICU illnesses like sepsis, major trauma, or open heart/abdominal surgery. It may help researchers understand why recovery can be harder in some people and guide future treatments.
Gainesville, FloridaAges 18–110 - NCT05263674RecruitingPhase 3
Faster ICU treatment for non-convulsive seizures in adults
This study compares two ways to stop non-convulsive seizures in the ICU. It tests whether fast sedation in intensive care works better than giving higher-dose anti-seizure medicine through a vein.
AarhusAges 18–120 - NCT05298982Enrolling by invitation
Join a long-term follow-up study for ICU care
This study follows people who joined the TEAM Phase III trial to learn how ICU care affects health over the long term. Your participation helps researchers understand outcomes long after the initial treatment.
Camperdown, New South WalesAges 18 years+ - NCT05279547Recruiting
Bed-cycle exercise study to test muscle oxygen during ICU care
This trial tests whether brief “interval” bed-cycling changes how well your leg muscles use oxygen compared with steady cycling. It’s meant for carefully selected ICU patients who can safely do active cycling while on ventilator support.
LeuvenAges 18 years+ - NCT05211661Recruiting
Diaphragm health during breathing machine support
This study looks at how the diaphragm (the main breathing muscle) changes when a person is on a breathing machine in the intensive care unit. It may help doctors understand how to better support breathing and recovery.
AachenAges 18–75 - NCT04876742Recruiting
Wheat beer to help prevent confusion in ICU patients
This study tests whether drinking wheat beer can lower the risk of delirium, a sudden confusion that can happen in intensive care. If you’re at higher risk and can take the study drink safely, this could help you avoid or reduce delirium.
BaselAges 18 years+ - NCT04910841Recruiting
Testing a glucose-monitoring device in septic shock ICU
This trial checks whether a continuous glucose monitoring system (“CGM GUARDIAN 2”) can be used safely and effectively for people in the ICU who have septic shock and high blood sugar. It may help the medical team track blood sugar more easily while you receive insulin.
NiceAges 18 years+ - NCT04848090Enrolling by invitation
Genetic testing for newborns in the hospital intensive care unit
This study uses whole-genome sequencing (a DNA test that looks across the genome) for newborns in the intensive care unit when doctors suspect a genetic condition. It aims to help identify possible genetic causes of illness and improve understanding for families and clinicians.
Pittsburgh, PennsylvaniaAges Up to 1 year - NCT03720860Recruiting
Study inflammatory signals in sudden kidney injury in ICU
This study looks at substances related to inflammation to better understand sudden kidney problems in people who are very sick in the ICU. It may help improve how kidney injury is predicted and treated after severe illness or major events.
Uppsala, Uppsala CountyAges 18 years+ - NCT04608630RecruitingPhase 2
Preventing bone loss in ICU patients with anti-bone drugs
This Phase 2 study tests whether zoledronic acid or denosumab can prevent bone thinning in critically ill adults after staying in the ICU. It may help reduce the risk of future bone fractures if your body is at higher risk during and after critical illness.
Sydney, New South WalesAges 50 years+ - NCT04670744Recruiting
Uses routine hospital records to find key care outcomes
This study looks at routinely collected anesthesia and intensive care information in hospital systems to find which signs and events best predict outcomes. It may help future patients by improving how care teams monitor and evaluate treatment.
Berlin, State of BerlinAges Up to 120 years - NCT02118467RecruitingPhase 4
Testing medicines that raise blood pressure in ICU shock patients
This trial studies whether “blood pressure–supporting” medicines (given through a central line) work well and safely for adults in the ICU who have shock. Your team may use the results to improve care for people with low blood pressure and poor blood flow to organs.
Chicago, IllinoisAges 18 years+ - NCT04180397RecruitingPhase 4
Removing extra fluid in critically ill ICU patients with overload
This trial studies a medicine strategy to remove extra fluid from the body in ICU patients who have fluid overload. It aims to see whether controlled fluid removal is safer and better for recovery than usual care.
SydneyAges 18 years+ - NCT04243356Enrolling by invitation
ICU nurse involvement in a post-ICU follow-up clinic
This study looks at whether having ICU nurses actively involved in a follow-up clinic after ICU discharge improves patients’ recovery and follow-up care. It focuses on patients who were cared for in the ICU and the registered nurses who cared for them.
Ann Arbor, MichiganAges 18 years+ - NCT03541785Enrolling by invitation
Using NGAL to guide fluids and start kidney-filtering in children
This study tests whether measuring a urine protein called NGAL can help doctors choose the right fluid amount and decide when to start a kidney-filtering treatment called CRRT in critically ill children with kidney injury. If it works, it may help treat kidney problems sooner and more safely.
Cincinnati, OhioAges 3 months–25 years - NCT02738645Recruiting
Study of pneumonia patients in the ICU
This study follows people who are admitted to a respiratory intensive care unit (a special ICU for breathing problems) because they have pneumonia. It may help doctors better understand pneumonia in ICU patients and improve care in the future.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06162247Recruiting
Registry study for heart patients in intensive care
This study tracks patients with sudden heart problems admitted to a special heart intensive care unit. It helps doctors learn more about these conditions to improve future care.
NaplesAges 18 years+ - NCT07553923Recruiting
High-intensity walking rehabilitation for spinal cord injury
This study tests whether intensive walking training helps people with incomplete spinal cord injuries regain walking ability. You would work with physical therapists on challenging walking exercises to improve strength and independence.
Edmonton, AlbertaAges 18 years+
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Common questions
- Are there clinical trials for intensive care?
- Yes. Clin2 currently lists 416 recruiting intensive care studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a intensive care trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a intensive care trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.