Periodontal Defect clinical trials

Gum surgery technique for deep pockets between teeth

This trial tests a surgical technique to treat deep gum pockets between teeth. It compares using a special gum-saving method alone, with a bone graft, or with a platelet-rich fibrin injection to see which helps heal the bone best.

Biologic gum treatments added to non-surgical cleaning

This trial studies whether adding a biologic medicine to standard non-surgical gum (periodontal) treatment can improve deep gum pockets in certain bone defects. It may help people whose gum disease has specific “intrabony” defects, but you must meet several health and medication rules.

Gum surgery to repair bone loss, with or without your own healing proteins

This trial tests a gum surgery technique that preserves more of your gum tissue, with or without a special protein-rich material made from your own blood (L-PRF), to repair bone loss from gum disease.

Injectable PRF and bone graft for gum disease bone defects

This trial tests a treatment for deep gum disease pockets using a combination of your own blood components (injectable platelet-rich fibrin) and a bone graft material. It aims to help regenerate bone lost to periodontitis.

Algae bone graft for gum disease bone defects

This study tests a new bone graft material made from algae, used with a collagen membrane, to help repair bone damage caused by gum disease. It might be an option if you have a deep pocket in the bone around a tooth and are healthy enough for the procedure.

Gum surgery for deep periodontal bone defects

This trial studies a specific gum surgery technique plus a biologic product to help fill deep gum/bone defects from periodontitis (gum disease). It may help reduce gum pocket depth and improve healing around affected teeth.

Treating deep gum pockets with laser or scalpel and platelet gel

This study compares two ways to fix deep gum pockets around teeth: a laser (MIST) or a traditional scalpel (GBT). Both methods use a gel made from your own blood (PRF) to help healing. The goal is to see which works better.

Study on gum tissue healing for severe gum disease

This trial tests whether special granulation tissue can help regenerate bone and gum support in people with severe gum disease who still have deep bone pockets after initial treatment. It may offer a better way to heal these defects.

Gum disease treatment with platelet-rich fibrin and albumin gel

This study tests a new treatment for severe gum disease. It combines a natural blood product (platelet-rich fibrin) with a special albumin gel to help repair bone defects around teeth. The goal is to see if this mixture helps the bone grow back better than standard treatment.

Early healing and gum surgery outcomes

This trial tests whether early wound healing affects the results of regenerative gum surgery, which aims to rebuild bone around teeth affected by advanced gum disease.

Hyaluronic acid and polynucleotides for gum disease treatment

This trial tests if a gel made from hyaluronic acid and polynucleotides can help repair gum damage in people with advanced gum disease. You may be eligible if you have deep pockets between your teeth and gums that haven't healed after standard cleaning.

Gel treatment for deep gum bone loss around teeth

This trial tests a special gel made with growth-promoting compounds and animal-derived material to help repair deep bone loss in the gums around teeth. It may help restore bone that periodontitis (advanced gum disease) has damaged.

Comparing tooth graft vs bone graft for gum disease bone loss

This trial tests if using a tooth that is removed (like a wisdom tooth) to fill deep gum pockets works as well as using a piece of your own bone. It may help rebuild the bone around a damaged tooth.

Two gum treatments for deep bone defects in teeth

This study tests whether one of two treatments can improve healing of “intra-bony” gum/bone defects around teeth after deep cleaning. It may help some people with periodontal disease who have pockets deep enough to involve the bone but with certain health and dental conditions.

Bone substitute for gum disease between tooth roots

This trial tests a bone substitute material to help repair gum defects between the roots of back teeth (molars) that have not healed with standard deep cleaning. If you have a single area of gum bone loss between the roots, this surgery might help regenerate the bone.

Bone substitutes with gum graft for deep gum pockets

This trial tests two different bone-filling materials combined with a gum graft to repair deep pockets in your gums caused by gum disease. The goal is to help your gums heal and regain support around your teeth.

Platelet-Rich Fibrin Injection for Gum Disease Treatment

This study tests a new injectable treatment using your own blood cells to help repair damaged gum tissue and bone around teeth affected by periodontal disease (gum disease). The goal is to see if this minimally invasive approach can regenerate healthy gum and bone without major surgery.

Enamel Matrix Derivative and Xenograft for Mandibular Molar Furcation Defects

Bone Graft Options for Gum Disease Surgery

This trial tests two bone-replacement materials (a synthetic bone substitute and a natural bone graft) placed during gum surgery to see which one better helps rebuild bone and gum support around teeth with deep pockets.

Comparing two gum-graft materials for bone defects

This study tests two types of gum-graft materials to see which works better for rebuilding bone next to deep pockets caused by gum disease. Both materials are used during a minor surgical procedure to help your gums and bone heal stronger.

Chitosan brush and enamel proteins for gum treatment

This trial tests a new way to clean deep gum pockets at the base of molars using a chitosan brush and enamel proteins. It's for people who still have gum problems after standard treatment.

Bone regeneration surgery for lower molar gum disease

This study looks at the shape of lower molar teeth with a certain type of gum disease and tests a surgical treatment to help regrow the bone around those teeth. If you have advanced gum disease and a lower molar with a specific type of bone loss, this treatment might help save the tooth.

Collagen membranes for healing after wisdom tooth surgery

This trial tests whether placing a collagen membrane after wisdom tooth removal helps the nearby second molar heal better. If you have impacted lower wisdom teeth on both sides, this study may compare healing with and without the membrane.

Injection treatment for deep gum pockets

This study tests whether injecting a special substance made from your own blood can help treat deep gum pockets without surgery. It may be an option for people with advanced gum disease who have already had initial cleaning.