Clinical trials
Kidney Dysfunction clinical trials
Below are recruiting kidney dysfunction clinical trials, each written for real people, not researchers. We’re tracking 26 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04752293Recruiting
Study of a kidney blood-pressure system in kids
This study looks at how a kidney-related blood-pressure system works in children and teenagers, comparing those with newly diagnosed primary (no known cause) high blood pressure to those with normal blood pressure. It may help doctors better understand childhood blood-pressure changes and guide future care.
Winston-Salem, North CarolinaAges 7–18 - NCT05715814RecruitingPhase 3
Test diabetes-pill type medicine on kidney dialysis safety
This Phase 3 trial studies the safety of an SGLT2 inhibitor (a diabetes medication that can affect kidney fluid handling) in people on peritoneal dialysis. The goal is to see how the treatment works in your type of dialysis and whether it causes any problems.
Toronto, OntarioAges 18 years+ - NCT06314230Recruiting
Genomics of chronic kidney transplant failure study
This study looks at how genes affect long-term kidney transplant health. It aims to understand why some transplanted kidneys fail over time, and may help personalize care for transplant recipients.
Westmead, New South WalesAges 18–75 - NCT05465044Recruiting
Twice-weekly dialysis for veterans starting kidney treatment
This study compares starting hemodialysis two times per week versus three times per week for veterans in their first year of dialysis. It aims to see if a less frequent schedule can be just as safe and effective for those who still make urine.
Long Beach, CaliforniaAges 18 years+ - NCT06535945RecruitingPhase 4
Albumin to protect kidney function after liver transplant
This trial tests whether giving albumin (a protein in your blood) after a liver transplant can help prevent or reduce kidney damage. It is for adults receiving their first liver-only transplant from a deceased donor.
Chambray-lès-ToursAges 18 years+ - NCT07222683Recruiting
How kidney transplant affects heart blood vessel health
This study looks at how receiving a kidney transplant changes the health of small blood vessels in the heart. It may help people with advanced kidney disease understand the benefits of transplant on their heart health.
Boston, MassachusettsAges 18 years+ - NCT05659589Recruiting
Using a kidney toxin level to predict heart effects in AKI
This study looks at whether measuring indoxyl sulfate, a substance that can build up when kidneys are injured, can help predict how blood vessels and the heart are affected during acute kidney injury (AKI). It may help doctors understand who is at higher risk of heart-related problems while AKI is happening.
AmiensAges 18 years+ - NCT06983730RecruitingEarly Phase 1
Vitamin B3 and Kidney Response to Exercise in Heat
This study tests how your kidneys respond to exercise in the heat, and whether taking vitamin B3 (niacin) changes that response. It might help protect the kidneys of people who work or exercise in hot conditions.
Boston, MassachusettsAges 18–45 - NCT07167368Recruiting
Exercise rehab for heart and kidney health
This trial tests whether a supervised exercise program can help people with heart failure and mild-to-moderate kidney problems. It might improve both your heart and kidney function.
Nantong, JiangsuAges 18–75 - NCT06025240Recruiting
Better antibody monitoring after kidney transplant
This study tests a new way to monitor harmful antibodies after a kidney transplant. It may help prevent transplant rejection over time.
Liverpool, MerseysideAges 18 years+ - NCT05344573Recruiting
Testing better blood-flow rhythms during heart bypass surgery
This trial studies ways to control the “pulsatility” (how the blood pressure pulses during circulation) while you are on a heart-lung bypass machine. It may help improve safety and heart function during planned heart surgery.
Aurora, ColoradoAges 50–70 - NCT05562869RecruitingPhase 3
Belatacept instead of tacrolimus for early kidney graft problems
This trial looks at replacing standard anti-rejection medicines (tacrolimus, a type of CNI, plus mycophenolate and possibly prednisone) with belatacept in adults who have early kidney graft dysfunction 3–12 months after a kidney transplant. It aims to see if belatacept can control rejection and protect kidney function in the right patients.
Nantes, Loire AtlantiqueAges 18–99 - NCT06431919Recruiting
Adding statin to carvedilol for cirrhosis with heart problems
This trial tests whether adding a statin (simvastatin) to the usual heart medication carvedilol helps people with both cirrhosis and a related heart problem live longer and avoid serious liver complications.
ChandigarhAges 18–65 - NCT06950931Enrolling by invitation
Urine test for kidney problem after transplant or biopsy
This study tests whether a special urine test can detect kidney problems early in people who have had a kidney transplant or who have chronic or acute kidney disease. It requires a first-morning urine sample and regular check-ups at the study hospital.
Martin, SlovakiaAges 18 years+ - NCT04626167RecruitingEarly Phase 1
Testing a bladder transplant done with a kidney transplant
This early-phase study is testing a combined bladder and kidney transplant approach for people whose bladder problems damage the kidneys. The goal is to see if this treatment can improve bladder and kidney outcomes and be done safely.
Rochester, MinnesotaAges 1–60 - NCT05812755RecruitingPhase 4
Study drug effects on blood vessels and organs in heart surgery
This Phase 4 trial studies vericiguat-like stimulation (a type of medicine that affects blood-vessel signaling) around the time of planned open-heart surgery. It aims to see whether this can change blood-vessel “reactivity” and reduce injury to organs during and after surgery.
Nashville, TennesseeAges 18 years+ - NCT05422534RecruitingPhase 3
CoQ10 plus exercise for people with advanced kidney disease
This trial tests whether a supplement called CoQ10, along with supervised exercise, can improve how the body uses energy in people on chronic dialysis. It may help with muscle function and overall health if your heart and dialysis situation are stable enough.
Sacramento, CaliforniaAges 18–75 - NCT07245186Enrolling by invitation
Healthy living program for kidney decline
This study tests a program to help people with chronic kidney disease (CKD) stay healthy through diet tracking and other proactive steps. It focuses on people whose kidney function has declined but who are not yet on dialysis.
Shanghai, Shanghai MunicipalityAges 18–90 - NCT05065372RecruitingPhase 1
Metformin test with automated insulin in teens with type 1
This Phase 1 study tests how adding metformin affects blood flow in the kidneys, insulin sensitivity, and overall heart/metabolic health in young people with type 1 diabetes. It may help researchers understand whether this combo is safe and beneficial alongside automated or pump/shot insulin care.
Aurora, ColoradoAges 12–25 - NCT06631820Recruiting
A study of epicatechin for muscle health in advanced kidney disease
This trial tests whether a natural supplement called epicatechin can improve muscle health in people with advanced chronic kidney disease (CKD). You may be able to join if you have low kidney function and are not planning to start dialysis or have a kidney transplant in the next 4 months.
Huddinge, Stockholm CountyAges 60 years+ - NCT07106879Recruiting
Pre-screening for future metabolic and psychiatric studies
This study does not test a new treatment. It is a pre-screening program to see if you might qualify for future clinical trials on metabolic conditions (like diabetes or weight issues) or psychiatric health (like depression or anxiety). You will be asked some questions and may do some basic health checks to see which future trials could be a good fit for you.
Brooklyn, New YorkAges 18 years+ - NCT07090512Recruiting
Ultrasound to predict kidney risk after transplant
This study uses ultrasound of donor kidneys to predict the risk of kidney problems after transplant. It may help doctors better understand transplant outcomes.
Jinan, ShandongAges 18 years+ - NCT07550790Recruiting
Preventing kidney injury during heart failure imaging scans
This study tests whether a specific water-based medication can prevent kidney damage when patients with acute heart failure need a CT scan with contrast dye. The trial focuses on people with mild-to-moderate kidney problems who are hospitalized for fluid buildup in the heart.
Seongnam-si, Gyeonggi-doAges 20 years+ - NCT06306963Recruiting
Stomach blood vessel condition and digestion symptoms study
This study looks at people with a stomach condition called gastric antral vascular ectasia (GAVE) to understand how it affects digestion and causes symptoms. Researchers want to learn if stomach muscle function problems are common in this condition.
Rochester, MinnesotaAges 19 years+
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Common questions
- Are there clinical trials for kidney dysfunction?
- Yes. Clin2 currently lists 26 recruiting kidney dysfunction studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a kidney dysfunction trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a kidney dysfunction trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.