Clinical trials
Lumbar Spinal Fusion clinical trials
Below are recruiting lumbar spinal fusion clinical trials, each written for real people, not researchers. We’re tracking 62 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05011942Enrolling by invitation
Study of Irrisept during low-back fusion surgery
This study looks at whether using Irrisept (an antiseptic placed during surgery) can help during primary low-back fusion operations. It is mainly aimed at people having their first low-back fusion for up to three levels.
Kansas City, KansasAges 18–85 - NCT04407338Recruiting
B-DYN device versus standard fusion for lumbar stenosis
This trial compares a specific spinal fusion approach (B-DYN) with the standard fusion surgery for people with lumbar spinal stenosis. It aims to improve function after surgery and check whether the newer approach is well tolerated.
BordeauxAges 40 years+ - NCT05648474Recruiting
Nerve monitoring during a low-back fusion surgery
This study tests whether special nerve monitoring during a low-back fusion helps make surgery safer and the results easier to judge. It’s for people having a specific type of low-back fusion on one or two levels.
Carlsbad, CaliforniaAges 18 years+ - NCT07743606Enrolling by invitationPhase 3
Pain medicine after lower back fusion surgery
This study tests whether taking a nonsteroidal anti-inflammatory drug (NSAID) like ibuprofen after lumbar spine fusion surgery is safe and helps with pain without affecting bone healing. It may offer an alternative to stronger pain medicines.
Philadelphia, PennsylvaniaAges 18 years+ - NCT07204288Recruiting
Lumbar and sacroiliac fusion study for people with previous implants
This study looks at how well certain Spinal Simplicity implants work over time for people who have already received them. You must have received a specific implant between 2022 and 2025 to qualify.
Overland Park, KansasAges 18 years+ - NCT06407063Recruiting
Long-term results after surgery for lumbar spinal stenosis
This study looks at patients who had back surgery for lumbar spinal stenosis and a condition called spondylolisthesis between 2007 and 2015. They want to see how many people needed another operation years later.
TromsøAges 18 years+ - NCT04992572RecruitingEarly Phase 1
Comparing two types of anesthesia for back decompression surgery
This early study compares two anesthesia approaches during lumbar decompression (back surgery to relieve pressure on nerves). It may help improve comfort and safety during surgery, but whether you personally benefit is not yet known.
Redwood City, CaliforniaAges 40–95 - NCT06603831Recruiting
3D digital surgery study for bone and joint procedures
This study tests whether 3D digital planning tools make surgeries for certain bone and joint problems more effective and cost-efficient. If you need a specific type of surgery on your forearm, pelvis, or spine, this trial could help determine if digital surgery improves your recovery.
Sabadell, BarcelonaAges 18–80 - NCT06075979Recruiting
Microbes and spine health: a surgical study
This study looks at whether certain microbes (tiny living things) are linked to spine problems like herniated discs or narrow spinal canals. It involves people who need spine surgery, and the findings might help explain why some spines wear out faster.
Jinan, ShandongAges 18–85 - NCT06367855RecruitingPhase 4
Dexamethasone before spine surgery for pain control
This study tests whether giving a single dose of the steroid dexamethasone before minimally invasive spine surgery can help reduce pain and inflammation afterward. It is for people aged 50–80 who are having surgery on 1 or 2 levels of their lower back and have not had spine surgery before.
Pathum Thani, Changwat Pathum ThaniAges 50–80 - NCT05058287RecruitingPhase 3
Steroid shot during low-back surgery
This trial tests whether using a steroid medicine (a steroid shot) around the time of low-back decompression surgery improves pain and recovery. It is for adults having a limited-area laminectomy, and it compares steroid use versus not using it.
New York, New YorkAges 18–85 - NCT05253326Recruiting
Relaxing muscle exercises after spine surgery
This trial tests whether a structured “progressive muscle relaxation” routine can reduce pain and help recovery after spine surgery. You may be asked to learn and practice the relaxation steps even if you’ve never done them before.
Istanbul, ÜsküdarAges 18 years+ - NCT07017634RecruitingPhase 3
Novosis Putty for spine fusion in lumbar disc disease
This trial tests a new bone graft putty (Novosis Putty) used during a specific type of spine fusion surgery (TLIF) to treat a worn-out disc causing low back and leg pain. The goal is to see if it works as well as or better than current options.
Baton Rouge, LouisianaAges 21–80 - NCT06484192Enrolling by invitationPhase 4
Pain control after lower back fusion surgery
This trial tests a new pain management plan for people having spinal fusion surgery on their lower back. It aims to find the best way to control pain while reducing side effects.
Philadelphia, PennsylvaniaAges 18 years+ - NCT06709391Recruiting
Spinal fusion vs. no surgery for chronic low back pain
This trial tests whether a spinal fusion surgery is better than staying with non-surgical treatments for people with long-term, severe low back pain from worn-out discs in the lower spine. It aims to find out which approach offers better pain relief and quality of life.
GothenburgAges 25–65 - NCT06462729RecruitingPhase 1/Phase 2
Testing a new bone graft for lower back fusion surgery
This trial tests a new bone graft material called LDGraft for people who need a single-level lower back fusion (anterior lumbar interbody fusion). It aims to see if the new graft is as good as or better than current options for helping bones heal together.
Fort Wayne, IndianaAges 22–80 - NCT04679844Recruiting
Test bone putty for back fusion versus bone graft alternatives
This study compares a ready-to-use bone putty to standard bone graft materials (with or without your own bone) during back fusion surgery for unstable lower back problems. It looks at whether the putty works as well or better to help the bones fuse and heal.
Irvine, CaliforniaAges 18 years+ - NCT07289737Recruiting
Comparing two spine surgeries for a slipped backbone
This study compares two types of spine surgery for a common condition where a lower back bone slips forward. It aims to see which surgery works better to relieve pain and improve function.
Yiwu, ZhejiangAges 50–90 - NCT03072927Recruiting
Study of Medicare patients after mild back decompression
This study uses Medicare records to look at outcomes for people who receive MILD or an interspinous process decompression procedure for lumbar spinal stenosis with nerve symptoms. It may help confirm how well these less-invasive procedures work in real-world patients.
Athens, AlabamaAges 18 years+ - NCT06950853Recruiting
Spinal surgery study using endoscopy to avoid fusion
This trial tests a less invasive spinal surgery using an endoscope (a small camera) to treat certain spine problems without fusing bones together, which may help you recover faster. It is for adults with specific types of back or leg pain from conditions like a failed previous fusion, a slipped vertebra, or a curved spine with narrowing.
BordeauxAges 18 years+ - NCT04066296RecruitingPhase 2
Testing a numbing medicine to improve back decompression outcomes
This Phase 2 study looks at whether a long-lasting local pain medicine (liposomal bupivacaine) can improve recovery and outcomes after surgery for lumbar stenosis (narrowing in the lower spine). You may be considered if you’re an adult needing decompression surgery and do not have reasons that would make surgery unsafe or different from the study’s plan.
Aurora, ColoradoAges 18 years+ - NCT06704906Recruiting
Spine fusion surgery with a new bone graft material
This study tests a new bone graft material (Fibergraft BG Putty) used with a special screw system (Viper Prime) during spine fusion surgery. It is for adults with lower back problems who need 1 to 3 vertebrae fused, and who are not smokers or have a very low bone density.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT07291388Recruiting
Retrolaminar block for lumbar fusion with multimodal pain control
This study tests whether adding a retrolaminar block (a type of back injection) to standard pain medicines helps reduce pain after lumbar spine fusion surgery. It may help you recover with less need for strong painkillers.
Santiago, Santiago MetropolitanAges 18–75 - NCT06089746Recruiting
Posture therapy for older veterans with spinal stenosis
This trial tests a non-invasive posture therapy for older veterans with lumbar spinal stenosis (a narrowing in the lower spine). It aims to reduce pain and improve walking without surgery.
Baltimore, MarylandAges 55–80
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Common questions
- Are there clinical trials for lumbar spinal fusion?
- Yes. Clin2 currently lists 62 recruiting lumbar spinal fusion studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a lumbar spinal fusion trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a lumbar spinal fusion trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.