Clinical trials
Lumbar Spinal Stenosis clinical trials
Below are recruiting lumbar spinal stenosis clinical trials, each written for real people, not researchers. We’re tracking 72 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05504499Recruiting
Test a new implant for low back pain with mild narrowing
This trial studies a new spine implant placed between the bones to help relieve low back pain. You may be a candidate if imaging shows mild-to-moderate spinal narrowing and you’ve already tried non-surgical treatments for at least 3 months.
Santa Rosa, CaliforniaAges 18 years+ - NCT06157177RecruitingPhase 4
M640 for acute low back pain study
This trial tests a new treatment (M640) for people with acute low back pain, with or without sciatica. It aims to see if M640 can help reduce pain quickly.
Auburn, AlabamaAges 18–80 - NCT06367855RecruitingPhase 4
Dexamethasone before spine surgery for pain control
This study tests whether giving a single dose of the steroid dexamethasone before minimally invasive spine surgery can help reduce pain and inflammation afterward. It is for people aged 50–80 who are having surgery on 1 or 2 levels of their lower back and have not had spine surgery before.
Pathum Thani, Changwat Pathum ThaniAges 50–80 - NCT06143813Recruiting
Precision treatment for lumbar nerve pain with targeted block
This trial tests if a targeted nerve root injection can improve outcomes for people with persistent leg pain from a compressed nerve in the lower back, with the goal of tailoring surgery more precisely.
Aarhus CAges 18 years+ - NCT07627282Recruiting
Understanding spine care evolution and patient outcomes
This study follows patients visiting a spine surgery department to better understand how care is provided and how patients do over time. It helps doctors improve treatment for spine problems like degeneration, deformity, injury, infection, or tumors.
BordeauxAges 18 years+ - NCT05963815Recruiting
Spine surgery follow-up using online patient-reported questionnaires
This study looks at recovery after planned (elective) surgery for common lower-back (“lumbar”) spine problems like slipped discs, disc bulges, and narrowing of the spinal canal. You may be asked to complete online questionnaires, and the study uses your answers to understand symptoms and outcomes after surgery.
Rotterdam, South HollandAges 18–80 - NCT06000319Enrolling by invitation
NMP fibers for spine fusion surgery
This study tests a new material called NMP fibers used during spine fusion surgery to treat conditions like degenerative disc disease, spinal stenosis, or spondylolisthesis. The goal is to see how well it works for patients having fusion in the neck or lower back.
Jasper, AlabamaAges 18 years+ - NCT05366140Recruiting
Implanet Jazz spine fusion for adults needing thoracolumbar stabilization
This trial looks at using the Implanet Jazz system during spine fusion surgery for adults who need stabilization in the middle-to-lower back. It may help patients by improving how well the fused spine heals and stays in place.
Lexington, KentuckyAges 18–100 - NCT05856539Recruiting
Numbing nerve block during minimally invasive low back surgery
This trial tests whether an “ESP block” (a numbing injection near the spine) can help control pain during minimally invasive low back fusion surgery. If you’re having this surgery, the goal is to improve comfort and reduce pain medicine needs.
New York, New YorkAges 18–80 - NCT07348419Recruiting
Pain blocks after single-level lumbar disc surgery
This study compares two types of pain-blocking injections (Quadro-Iliac vs Thoracolumbar Interfascial Plane Block) to see which provides better pain relief after a single-level lumbar disc surgery. If you are having this surgery, the trial may help you have less pain and use fewer pain medicines afterwards.
SamsunAges 18–70 - NCT07328282Recruiting
Comparing two therapies for leg pain from a disc problem
This study compares two types of gentle movement therapies to see which works better for leg pain caused by a mild disc problem in the lower back. It may help you if you have pain going down one leg and meet a few specific physical exam findings.
Islamabad, Punjab ProvinceAges 30–50 - NCT05986370Recruiting
Study on back pain and spinal manipulation
This trial tests whether spinal manipulation therapy (a type of hands-on treatment) can help people with long-term low back pain. It also compares their results to healthy volunteers of the same age and sex.
Trois-Rivières, QuebecAges 18–60 - NCT06704906Recruiting
Spine fusion surgery with a new bone graft material
This study tests a new bone graft material (Fibergraft BG Putty) used with a special screw system (Viper Prime) during spine fusion surgery. It is for adults with lower back problems who need 1 to 3 vertebrae fused, and who are not smokers or have a very low bone density.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT06950853Recruiting
Spinal surgery study using endoscopy to avoid fusion
This trial tests a less invasive spinal surgery using an endoscope (a small camera) to treat certain spine problems without fusing bones together, which may help you recover faster. It is for adults with specific types of back or leg pain from conditions like a failed previous fusion, a slipped vertebra, or a curved spine with narrowing.
BordeauxAges 18 years+ - NCT04418830Enrolling by invitation
Study of a spine cage implant for degenerative back problems
This trial studies how well specific lumbar (lower back) implant “cages” help fuse vertebrae in people with degenerative disc disease, spinal slippage, narrowing, curvature, or forward-bending deformity. It may help by testing an approach to improve stability and reduce symptoms after surgery.
La Jolla, CaliforniaAges 18 years+ - NCT05745129Enrolling by invitation
AI tool for personalized care decisions in spine problems
This trial looks at using an artificial intelligence (AI) tool to help guide care choices for people with spine problems. It may help doctors assess whether you need surgery or a different approach, especially when disc herniation isn’t the main issue.
Oslo, NorgeAges 18–80 - NCT07001969Enrolling by invitation
Percutaneous facet spine fixation for instability
This study tests a minimally invasive procedure to fix unstable vertebrae in the neck or lower back using a small incision. It may help people with spinal instability causing nerve symptoms or pressure on the spinal cord.
Cairo, ShoroukAges Any age - NCT06101108Recruiting
Early heart screening in back surgery patients
This trial checks people having back surgery for spinal stenosis to see if they have an early sign of heart amyloidosis (a protein buildup in the heart). The goal is to find this condition early so it can be treated before it causes problems.
BrugesAges 60 years+ - NCT06528730Recruiting
Study on new surgical guidelines for cervical myelopathy in Chinese patients
This trial is testing a new set of surgical criteria for people of Chinese ethnicity with a condition called degenerative cervical myelopathy (a spinal cord problem in the neck). It aims to see if these criteria can better identify who should have surgery.
Hong KongAges 45 years+ - NCT03304730Recruiting
Tracking pain patterns after low back joint injections
This study follows adults with long-lasting low back pain to learn what predicts who improves after a specific type of back joint injection. It mainly helps doctors understand which factors relate to better or worse outcomes over time.
São Paulo, São PauloAges 18 years+ - NCT06024785Recruiting
Vertebropexy trial for lumbar spine surgery
This trial compares a new surgical technique called vertebropexy to standard fusion surgery for people with lower back problems like spinal canal narrowing or slipped vertebrae. The goal is to see if vertebropexy works as well or better with less recovery time.
ZurichAges 18 years+ - NCT06415110Enrolling by invitation
Comparing bone grafts for lower back fusion surgery
This study tests if a special bone graft material (Allosync Expand) plus your own bone is as good as using just your own bone for spinal fusion surgery. It might help people with back or leg pain caused by a slipped vertebra and narrowed spine.
Southfield, MichiganAges 22 years+ - NCT07050966Recruiting
Two hand therapies for nerve pain in the leg
This study compares two gentle hand techniques (Maitland and Mulligan) to see which one better relieves leg pain from a pinched nerve in the lower back. If you have chronic sciatica-type pain, these treatments may help without surgery.
IslamabadAges 18–65 - NCT05508360Recruiting
Testing an artificial spacer implant for one-level low back pain
This study tests whether inserting a small artificial implant into a single painful disc can reduce long-term low back pain and disability. It’s for people who tried non-surgical treatments for at least 6 months but still have significant symptoms from degenerative disc disease.
Medellín, AntioquiaAges 22 years+
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Common questions
- Are there clinical trials for lumbar spinal stenosis?
- Yes. Clin2 currently lists 72 recruiting lumbar spinal stenosis studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a lumbar spinal stenosis trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a lumbar spinal stenosis trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.