Clinical trials
Lung Cancer (NSCLC) clinical trials
Below are recruiting lung cancer (nsclc) clinical trials, each written for real people, not researchers. We’re tracking 1,079 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07697586RecruitingPhase 2
Two new drugs for advanced lung cancer without EGFR or ALK
This trial tests a combination of two new drugs, SKB264 and SKB118, for people with advanced non-small cell lung cancer. It may be an option if your cancer does not have the EGFR or ALK gene changes and you are in relatively good health.
Jilin CityAges 18–75 - NCT07647094RecruitingPhase 2
Chemotherapy plus immunotherapy for advanced squamous lung cancer
This trial tests a combination of three drugs—two chemotherapy medications (carboplatin and nab-paclitaxel) plus an immunotherapy drug (serplulimab)—as a first-line treatment for advanced squamous cell non-small cell lung cancer. The goal is to see if this combination works better than standard treatment and is safe for patients who haven't received prior systemic cancer treatment.
Quzhou, ZhejiangAges 18–75 - NCT07646288Recruiting
Visual Feedback Breathing Training After Lung Cancer Surgery
This study tests whether using visual feedback (like watching a screen) during breathing exercises helps lung cancer patients recover better after surgery to remove part of a lung. The goal is to see if this type of guided breathing practice improves how well your lungs work after the operation.
Ankara, AltındağAges 18–75 - NCT07645222RecruitingPhase 1
Testing HS-20122 combined therapy for advanced lung cancer
This early-stage trial tests a new drug combination (HS-20122) for non-small cell lung cancer that has spread or cannot be surgically removed. You may qualify if your cancer has progressed despite prior treatment or you haven't received prior treatment yet.
Guangzhou, GuangdongAges 18–75 - NCT07534033RecruitingPhase 2
Probiotic LR607 for newly diagnosed lung cancer
This study tests whether a probiotic supplement (LR607) can help patients with newly diagnosed non-small cell lung cancer—a common type of lung cancer. Probiotics are beneficial bacteria that may help your immune system fight cancer alongside standard treatments.
GuangzhouAges 18–80 - NCT06769295RecruitingPhase 2
Study of AK112 plus chemo for advanced lung cancer
This trial tests a new drug, AK112, combined with chemotherapy for people with advanced non-squamous non-small cell lung cancer that has spread to the lining of the lung (malignant pleural effusion). The goal is to see if this combination helps shrink tumors and improve outcomes.
Chengdu, SichuanAges 18–75 - NCT07398209Recruiting
Motion management study for lung cancer patients having radiation
This study uses MRI scans to understand how tumor motion affects radiation therapy planning in lung cancer. It is for patients who are starting radiation treatment, possibly with chemotherapy or immunotherapy.
Baltimore, MarylandAges 18 years+ - NCT05473156RecruitingPhase 1/Phase 2
Study of AP203 for advanced solid tumors that grew despite treatment
This early-phase study tests AP203 (an investigational treatment) to see if it is safe and to look for signs it can shrink or control certain advanced cancers. The study includes a dose-finding part for many solid tumors, and a second part focused on specific lung and head/neck cancers that previously received PD-1/PD-L1 therapy.
TaipeiAges 18 years+ - NCT06111807Recruiting
Validating blood tests for stage III lung cancer
This trial is testing whether new blood tests can reliably detect and monitor stage III non-small cell lung cancer (NSCLC). It hopes to improve how doctors track your cancer and decide on treatment.
Nice, NiceAges 18 years+ - NCT07252739RecruitingPhase 2
Study of pembrolizumab plus MK-1084 for KRAS G12C lung cancer
This trial tests a combination of two drugs for people with advanced non-small cell lung cancer that has a specific mutation called KRAS G12C. The goal is to see if the combination works better than current treatments.
Clermont, FloridaAges 18 years+ - NCT04624373Recruiting
Test tumor DNA from breath biopsy samples
This study checks tiny pieces of DNA from a sample taken during a breathing-tube biopsy (EBUS-TBNA) to better identify certain lung cancer changes. It may help doctors learn more about the type of lung cancer and, in some cases, why targeted treatments stop working.
ToulouseAges 18–65 - NCT07213375RecruitingPhase 2/Phase 3
High-dose steroid to reduce pain after lung surgery
This trial tests if a high dose of dexamethasone (a steroid) can lower pain after keyhole lung surgery. If you are having planned keyhole lung surgery for a lobe or segment, you may be eligible.
Copenhagen, CopenhagenAges 18 years+ - NCT06921681Recruiting
Ultrasound-guided biopsy of chest lymph nodes
This trial uses a special ultrasound-guided procedure to take tissue samples from swollen lymph nodes in the chest. It aims to improve diagnosis for people who already need a bronchoscopy.
BaselAges 18–90 - NCT07135856Recruiting
Lung-saving surgery after pre-surgery therapy for NSCLC
This trial studies how well sleeve lobectomy (a type of lung-saving surgery) works for people with non-small cell lung cancer who have already received therapy like chemotherapy or immunotherapy before surgery. It aims to see if this approach is safe and effective.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT07130786RecruitingPhase 2
Preventing seizures with medication for brain tumors in movement area
This study tests whether giving a seizure medication (levetiracetam) to people with brain tumors in the movement area can prevent seizures. It compares taking the medication to not taking it, starting before any seizure occurs.
Boston, MassachusettsAges 18 years+ - NCT07132190RecruitingPhase 2
Radiation for growing brain tumors with same-day planning
This study tests whether a precise, one-day radiation treatment for brain tumors that are growing or in tricky spots can be effective with a smaller safety margin. It's designed for people whose brain tumors are changing quickly or sitting near areas of swelling or recent surgery.
Boston, MassachusettsAges 18 years+ - NCT07061379Recruiting
Patient feedback in first-line lung cancer treatment study
This study collects patient feedback through questionnaires to see if it helps improve outcomes for people with advanced non-small-cell lung cancer starting chemo-immunotherapy. It may help your care team better understand how you are feeling.
Milan, ItalyAges 18 years+ - NCT06974370RecruitingPhase 2
Avoiding brain radiation when chemo or other drugs work
This trial tests whether some people with brain metastases from solid tumors can safely skip radiation if their cancer drugs (like targeted therapy, immunotherapy, or certain chemotherapies) shrink the brain tumors. You will get MRI scans to see if the drugs are working.
Burlington, VermontAges 18 years+ - NCT06865339RecruitingPhase 2
Radiation plus immunotherapy for advanced lung cancer
This trial tests whether adding two immunotherapy drugs (cemiplimab and fianlimab) to standard radiation and chemotherapy can help treat locally advanced non-small cell lung cancer that hasn't been treated before.
The Bronx, New YorkAges 18 years+ - NCT05754203Recruiting
Radiation plus immunotherapy for advanced lung cancer
This trial studies whether a more intensive form of targeted radiation, combined with immunotherapy (immune checkpoint inhibitors), can work better and be safe for people with advanced non-small cell lung cancer. You may be considered if your tumor is limited in size and you’re able to receive both treatments.
Chongqing, Chongqing MunicipalityAges 18–75 - NCT06800586Recruiting
Air pollution and health: new early warning signs
This study looks for new early warning signs (biomarkers) of how air pollution affects lung and blood health. It is for people with COPD, lung cancer, or leukemia who have never smoked much, as well as for healthy hospital workers.
Bologna, BolognaAges 18 years+ - NCT06738160RecruitingPhase 2
Combination therapy for advanced lung cancer with bone metastases
This trial tests a new combination of drugs and radiation to improve the effects of first-line chemotherapy and immunotherapy for patients with advanced non-small cell lung cancer that has spread to the bones. The goal is to help shrink tumors and potentially improve overall outcomes.
Shanghai, Shanghai MunicipalityAges 18–80 - NCT06476808RecruitingPhase 1
Testing a new drug for advanced solid tumors
This trial tests an investigational drug (BMS-986463) in people with advanced solid tumors. It aims to find a safe dose and see if it helps shrink or control the cancer. You must be well enough to do daily activities and have a tumor that can be biopsied before treatment starts.
Los Angeles, CaliforniaAges 18 years+ - NCT06457789Recruiting
PET scans to track immune response in lung cancer treatment
This study uses special PET scans to see how well your immune cells respond to immunotherapy given before surgery for non-small cell lung cancer. The goal is to learn which patients benefit most from this treatment approach.
Amsterdam, North HollandAges 18 years+
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Common questions
- Are there clinical trials for lung cancer (nsclc)?
- Yes. Clin2 currently lists 1,079 recruiting lung cancer (nsclc) studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a lung cancer (nsclc) trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a lung cancer (nsclc) trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.