Clinical trials
Major Cardiovascular Event clinical trials
Below are recruiting major cardiovascular event clinical trials, each written for real people, not researchers. We’re tracking 32 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07136012RecruitingPhase 3
Olpasiran trial to lower Lp(a) and prevent first heart attack or stroke
This trial tests if olpasiran can lower a type of cholesterol called Lp(a) to help prevent a first major heart attack, stroke, or other heart problems. It is for people at higher risk due to risk factors or early signs of artery disease, but who have not yet had a heart attack or stroke.
Alexander City, AlabamaAges 50–105 - NCT06295679Recruiting
Repatha plus standard care for heart disease in Chinese patients
This study tests whether adding Repatha (a weekly injection that lowers cholesterol) to your usual heart medications can reduce the risk of future heart attacks, strokes, or other heart problems. It is for people who have already had a heart attack or stroke, or have certain high-risk conditions.
Beijing, Beijing MunicipalityAges 18–150 - NCT06318767Recruiting
Foot Blood Flow Measurements to Predict Limb and Heart Events
This study measures how blood flows through your foot using ultrasound to see if it can predict serious problems with your leg or heart in people with severe circulation problems. The goal is to find a simple test that helps doctors decide the best treatment for you.
AmiensAges 18 years+ - NCT06919302Recruiting
Digital heart health app for heart disease patients
This study tests a digital heart health app combined with lifestyle coaching to help people with heart disease or diabetes manage their cholesterol and overall heart health. It aims to see if the app can improve outcomes for people already taking a statin.
Toronto, OntarioAges 45 years+ - NCT07168421RecruitingPhase 4
Landiolol to prevent fast heart rate during major surgery
This trial tests a short-acting medicine called landiolol to see if it can prevent dangerously fast heart rates during and after major surgery. It is for people who have heart risks and are having a planned non-cardiac surgery.
BernAges 45 years+ - NCT07554820RecruitingPhase 4
Heart Protection in Rheumatoid Arthritis With New Medications
This study compares two treatment approaches for people with active rheumatoid arthritis who also have heart disease risk factors. It tests whether a newer drug called tofacitinib, combined with cholesterol medication, can better protect the heart than traditional TNF-inhibitor treatments.
Lahore, Punjab ProvinceAges 50–85 - NCT06204549Recruiting
Managing health issues to lower heart risk
This trial checks if treating other health problems during a hospital stay can help lower your risk of heart disease or stroke. It is for people who either have never had a heart event but have several risk factors, or who have already had a major heart event.
MontpellierAges 18 years+ - NCT07039149Recruiting
Dual antiplatelet therapy for acute coronary syndrome
This trial tests giving two blood-thinning medicines early to people who have had a heart attack or unstable chest pain. Researchers want to see if this approach reduces future heart problems.
AmmanAges 18 years+ - NCT07157774RecruitingPhase 3
Muvalaplin for heart disease in people with high lipoprotein(a)
This study tests a new medicine called muvalaplin that lowers a specific type of cholesterol linked to heart disease. It aims to see if muvalaplin can reduce the risk of future heart attacks, strokes, or related procedures in people with high levels of this cholesterol.
Birmingham, AlabamaAges 18 years+ - NCT04646252Recruiting
Testing a blood-surface feature to prevent heart problems
This study looks at whether a healthy blood lining (the glycocalyx) can help predict and reduce the risk of major heart events in people who have not yet had heart disease. You may be asked to do screening tests and share health information to see how these factors relate to future risk.
Athens, AtticaAges 18–85 - NCT07634666Recruiting
Heart Safety Monitoring During Urologic Cancer Surgery
This study tracks heart health before and after major surgery for prostate or kidney cancer in older adults. Researchers want to predict which patients might experience heart problems after surgery so they can provide better care.
SeoulAges 60 years+ - NCT03720613Recruiting
Testing medicines to prevent heart events in opioid constipation
This study looks at how well naldemedine (and certain other constipation medicines) lower the risk of major heart problems in people who take opioids for constipation. It compares medicine use patterns in people with opioid-induced constipation to see who has fewer serious heart events.
Wilmington, DelawareAges 18 years+ - NCT04691037Recruiting
CT heart scan to guide care for stable chest pain
This trial studies whether a CT heart scan (CCTA) can better guide treatment decisions for people with stable chest pain caused by blocked heart arteries. It may help your care team choose the next best step based on scan results.
Beijing, Beijing MunicipalityAges 18 years+ - NCT05378035Recruiting
DOAC interruption study for Chinese people with atrial fibrillation
This trial studies how safely and effectively to pause a blood thinner (a DOAC) for about 48 hours before an elective procedure in people with atrial fibrillation. It may help confirm the best way to reduce bleeding risk without raising stroke risk.
Hong KongAges 18–80 - NCT05578300Recruiting
Translating thrombectomy care into real-world practice in Asia-Pacific
This study aims to help endovascular thrombectomy for certain severe strokes work well in everyday hospital care across Asia-Pacific. You may be considered if you’re an adult with a specific type of stroke blocked in a major brain blood vessel.
Linyi, ShandongAges 18 years+ - NCT05662293Recruiting
Study of heart muscle weakness caused by abnormal heart rhythms
This study looks at a condition where an abnormal heart rhythm can weaken the heart muscle (arrhythmia-induced cardiomyopathy). You may be asked questions, have heart tests reviewed, and help researchers better describe who is affected and how it develops.
BaselAges 18 years+ - NCT06537583Recruiting
Ear stimulation after a STEMI heart attack
This study tests whether gentle electrical stimulation near your ear (tragus) can help stabilize your heart's rhythm and reduce inflammation after a STEMI heart attack. It may help lower the risk of future heart problems.
Semarang, Central of JavaAges 18–70 - NCT06586424Recruiting
Can Anion Gap Predict Heart Risks After a Heart Attack?
This study checks if a simple blood test measure (anion gap) can help predict serious heart problems in people who have had a major heart attack (STEMI) and received emergency angioplasty. It may help doctors better understand your risk and guide future care.
Semarang, Central of JavaAges 18–70 - NCT06843005Recruiting
Heart CT scan study for plaque changes in mild coronary disease
This study uses repeat CT scans of the heart to see how plaque buildup changes over time in people with mild, non-blocking coronary artery disease. It may help doctors decide on better treatments to prevent future heart problems.
Nanjing, JiangsuAges 18–80 - NCT06885619Recruiting
Predicting heart outcomes after a first heart attack with blood tests
This study looks at blood tests and heart function after a first heart attack (STEMI) treated with emergency stenting. Researchers want to see if certain molecules in the blood can predict future heart problems.
Beijing, Beijing MunicipalityAges 18–80 - NCT05732714Recruiting
Reduce heart event risk after major non-heart surgery
This study looks at ways to lower the chance of heart-related problems after major surgery that is not directly related to the heart. It focuses on people at higher heart risk who are expected to stay in the hospital for at least two days after surgery.
Toronto, OntarioAges 45–75 - NCT06909565RecruitingPhase 4
Inclisiran to prevent heart and leg events after artery procedure
This study tests whether a twice-yearly injection called inclisiran can prevent heart attacks, strokes, or leg complications in people who recently had a procedure to open a blocked artery. You may be eligible if you had a heart or leg artery procedure within the last two weeks.
Alexander City, AlabamaAges 18 years+ - NCT07000357RecruitingPhase 3
Study of AZD0780 to reduce heart attack and stroke risk
This trial tests a new medication, AZD0780, to see if it helps prevent major cardiovascular events like heart attacks or strokes in people who already have heart or blood vessel disease, or are at high risk for a first event. It might be a good fit if your cholesterol isn't well-controlled despite current treatments.
Athens, AlabamaAges 18 years+ - NCT05531474Recruiting
Bariatric surgery to lower future heart and stroke events
This trial looks at whether weight-loss surgery can reduce the chances of heart attack, stroke, or other serious heart problems in people at higher heart risk. You might be offered surgery and followed over time to see if cardiovascular events are reduced.
Hamilton, OntarioAges 18 years+
Hear when a new Major Cardiovascular Event trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for major cardiovascular event?
- Yes. Clin2 currently lists 32 recruiting major cardiovascular event studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a major cardiovascular event trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a major cardiovascular event trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.