Clinical trials
Major Cardiovascular Event clinical trials
Below are recruiting major cardiovascular event clinical trials, each written for real people, not researchers. We’re tracking 27 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07136012RecruitingPhase 3
Olpasiran trial to lower Lp(a) and prevent first heart attack or stroke
This trial tests if olpasiran can lower a type of cholesterol called Lp(a) to help prevent a first major heart attack, stroke, or other heart problems. It is for people at higher risk due to risk factors or early signs of artery disease, but who have not yet had a heart attack or stroke.
Alexander City, AlabamaAges 50–105 - NCT06919302Recruiting
Digital heart health app for heart disease patients
This study tests a digital heart health app combined with lifestyle coaching to help people with heart disease or diabetes manage their cholesterol and overall heart health. It aims to see if the app can improve outcomes for people already taking a statin.
Toronto, OntarioAges 45 years+ - NCT06318767Recruiting
Foot Blood Flow Measurements to Predict Limb and Heart Events
This study measures how blood flows through your foot using ultrasound to see if it can predict serious problems with your leg or heart in people with severe circulation problems. The goal is to find a simple test that helps doctors decide the best treatment for you.
AmiensAges 18 years+ - NCT07168421RecruitingPhase 4
Landiolol to prevent fast heart rate during major surgery
This trial tests a short-acting medicine called landiolol to see if it can prevent dangerously fast heart rates during and after major surgery. It is for people who have heart risks and are having a planned non-cardiac surgery.
BernAges 45 years+ - NCT07554820RecruitingPhase 4
Heart Protection in Rheumatoid Arthritis With New Medications
This study compares two treatment approaches for people with active rheumatoid arthritis who also have heart disease risk factors. It tests whether a newer drug called tofacitinib, combined with cholesterol medication, can better protect the heart than traditional TNF-inhibitor treatments.
Lahore, Punjab ProvinceAges 50–85 - NCT07039149Recruiting
Dual antiplatelet therapy for acute coronary syndrome
This trial tests giving two blood-thinning medicines early to people who have had a heart attack or unstable chest pain. Researchers want to see if this approach reduces future heart problems.
AmmanAges 18 years+ - NCT07157774RecruitingPhase 3
Muvalaplin for heart disease in people with high lipoprotein(a)
This study tests a new medicine called muvalaplin that lowers a specific type of cholesterol linked to heart disease. It aims to see if muvalaplin can reduce the risk of future heart attacks, strokes, or related procedures in people with high levels of this cholesterol.
Birmingham, AlabamaAges 18 years+ - NCT04646252Recruiting
Testing a blood-surface feature to prevent heart problems
This study looks at whether a healthy blood lining (the glycocalyx) can help predict and reduce the risk of major heart events in people who have not yet had heart disease. You may be asked to do screening tests and share health information to see how these factors relate to future risk.
Athens, AtticaAges 18–85 - NCT04691037Recruiting
CT heart scan to guide care for stable chest pain
This trial studies whether a CT heart scan (CCTA) can better guide treatment decisions for people with stable chest pain caused by blocked heart arteries. It may help your care team choose the next best step based on scan results.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07634666Recruiting
Heart Safety Monitoring During Urologic Cancer Surgery
This study tracks heart health before and after major surgery for prostate or kidney cancer in older adults. Researchers want to predict which patients might experience heart problems after surgery so they can provide better care.
SeoulAges 60 years+ - NCT05662293Recruiting
Study of heart muscle weakness caused by abnormal heart rhythms
This study looks at a condition where an abnormal heart rhythm can weaken the heart muscle (arrhythmia-induced cardiomyopathy). You may be asked questions, have heart tests reviewed, and help researchers better describe who is affected and how it develops.
BaselAges 18 years+ - NCT06885619Recruiting
Predicting heart outcomes after a first heart attack with blood tests
This study looks at blood tests and heart function after a first heart attack (STEMI) treated with emergency stenting. Researchers want to see if certain molecules in the blood can predict future heart problems.
Beijing, Beijing MunicipalityAges 18–80 - NCT06843005Recruiting
Heart CT scan study for plaque changes in mild coronary disease
This study uses repeat CT scans of the heart to see how plaque buildup changes over time in people with mild, non-blocking coronary artery disease. It may help doctors decide on better treatments to prevent future heart problems.
Nanjing, JiangsuAges 18–80 - NCT05578300Recruiting
Translating thrombectomy care into real-world practice in Asia-Pacific
This study aims to help endovascular thrombectomy for certain severe strokes work well in everyday hospital care across Asia-Pacific. You may be considered if you’re an adult with a specific type of stroke blocked in a major brain blood vessel.
Linyi, ShandongAges 18 years+ - NCT05378035Recruiting
DOAC interruption study for Chinese people with atrial fibrillation
This trial studies how safely and effectively to pause a blood thinner (a DOAC) for about 48 hours before an elective procedure in people with atrial fibrillation. It may help confirm the best way to reduce bleeding risk without raising stroke risk.
Hong KongAges 18–80 - NCT03720613Recruiting
Testing medicines to prevent heart events in opioid constipation
This study looks at how well naldemedine (and certain other constipation medicines) lower the risk of major heart problems in people who take opioids for constipation. It compares medicine use patterns in people with opioid-induced constipation to see who has fewer serious heart events.
Wilmington, DelawareAges 18 years+ - NCT06909565RecruitingPhase 4
Inclisiran to prevent heart and leg events after artery procedure
This study tests whether a twice-yearly injection called inclisiran can prevent heart attacks, strokes, or leg complications in people who recently had a procedure to open a blocked artery. You may be eligible if you had a heart or leg artery procedure within the last two weeks.
Alexander City, AlabamaAges 18 years+ - NCT07000357RecruitingPhase 3
Study of AZD0780 to reduce heart attack and stroke risk
This trial tests a new medication, AZD0780, to see if it helps prevent major cardiovascular events like heart attacks or strokes in people who already have heart or blood vessel disease, or are at high risk for a first event. It might be a good fit if your cholesterol isn't well-controlled despite current treatments.
Athens, AlabamaAges 18 years+ - NCT07783802RecruitingPhase 2
Study of clazakizumab for adults with high inflammation and heart risk
This study tests whether clazakizumab can reduce the risk of heart attacks or strokes in people with high levels of inflammation (measured by a blood test called hsCRP) and conditions like heart disease, obesity, diabetes, high blood pressure, or kidney disease. If you qualify, you'll receive either the study drug or a placebo to see if it helps lower your risk.
Huntsville, AlabamaAges 18 years+ - NCT05531474Recruiting
Bariatric surgery to lower future heart and stroke events
This trial looks at whether weight-loss surgery can reduce the chances of heart attack, stroke, or other serious heart problems in people at higher heart risk. You might be offered surgery and followed over time to see if cardiovascular events are reduced.
Hamilton, OntarioAges 18 years+ - NCT07293260RecruitingPhase 3
Olpasiran heart scan study for high Lp(a) patients
This study tests if a medication called olpasiran can lower a type of fat in your blood called Lp(a), which is linked to heart problems. You take the medicine or a placebo and get a special heart scan to see changes in your arteries.
Bridgeport, ConnecticutAges 35–80 - NCT07719894RecruitingPhase 4
Preventing heart problems in type 2 diabetes with cilostazol and aspirin
This trial tests whether taking cilostazol and aspirin together can help prevent heart attacks, strokes, and other cardiovascular events in people with type 2 diabetes who have early signs of artery disease or metabolic syndrome. It aims to see if this combination is more effective than aspirin alone.
Seongnam-si, Gyeonggi-doAges 19 years+ - NCT06820970Recruiting
Combined therapy for heart artery blockages that weren't fully opened
This trial tests if combining a new heart procedure with a special type of therapy called mindfulness therapy can help prevent heart problems in people with coronary artery disease that could not be fully fixed with stents or surgery.
Zhengzhou, HenanAges 18 years+ - NCT05812248Recruiting
Tracking heart and blood vessel events after major non-heart surgery
This study follows people after major surgery to see what predicts heart and blood vessel problems later. It does not test a new drug; it mainly collects health information to help clinicians reduce risk.
Guangzhou, GuangdongAges 45 years+
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Common questions
- Are there clinical trials for major cardiovascular event?
- Yes. Clin2 currently lists 27 recruiting major cardiovascular event studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a major cardiovascular event trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a major cardiovascular event trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.