Clinical trials
Medication Safety clinical trials
Below are recruiting medication safety clinical trials, each written for real people, not researchers. We’re tracking 383 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06713382RecruitingPhase 2
Saline rinse for trapped lung infections
This trial tests if adding a simple saltwater rinse to standard chest tube drainage helps clear stubborn lung infections. It might be an option if you have an infected fluid pocket in your chest that isn't draining well.
Boston, MassachusettsAges 18 years+ - NCT05024097RecruitingPhase 2
New medicines with chemotherapy after short radiation for rectal cancer
This trial tests two new immune-related medicines (an anti–PD-1 drug and an adenosine blocker) added to standard chemotherapy after a short course of radiation for rectal cancer. It aims to improve cancer control while checking safety.
New York, New YorkAges 18–90 - NCT07653295Recruiting
Study of Tıpmed revision hip replacement safety
This study follows patients who already had a revision hip replacement using the Tıpmed system. Researchers want to confirm the implant is safe and works well over time.
BalıkesirAges 18 years+ - NCT07249879RecruitingPhase 1
CAR-T cell therapy for DLL3-positive small cell lung cancer
This trial tests a new CAR-T cell therapy (GC511B) for people with a specific type of small cell lung cancer that has DLL3 protein. The treatment uses your own immune cells to target and attack the cancer.
Beijing, Beijing MunicipalityAges 18–75 - NCT05757245RecruitingPhase 1
Safety and effectiveness of GMCN-508A for transfusion-dependent alpha thalassemia
This Phase 1 study tests a new medicine (GMCN-508A) to see how safe it is and whether it can help people with transfusion-dependent alpha thalassemia. Participants are also expected to follow a treatment plan that includes stem cell transplantation preparation.
Nanning, GuangxiAges 5–35 - NCT06431620Recruiting
Thyroid cancer scan with help of a special hormone
This study tests if a man-made hormone (rhTSH) can make radioactive iodine therapy more effective for people with advanced thyroid cancer that has come back or spread. It aims to see if it helps find and treat cancer that doesn't respond well to standard radioactive iodine.
Nanjing, JiangsuAges 18–75 - NCT05410925RecruitingPhase 4
Half-dose r-SAK before heart stent procedure for heart attack
This trial tests whether a half-dose medicine called r-SAK given before a primary PCI heart stent procedure improves outcomes and safety in people with a specific type of heart attack. It may help the heart recover better, but it also checks the risk of side effects like bleeding.
Nanjing, JiangsuAges 18–75 - NCT07418112RecruitingPhase 4
Laser vs other device for hard bile or pancreas stones
This study compares two types of lithotripsy (stone-breaking) devices, holmium laser and electrohydraulic lithotripsy, for treating difficult stones in the bile or pancreatic ducts. If you have a bile or pancreas stone that is large, stuck, or could not be removed with standard procedures, this trial may help determine which method works best.
Chicago, IllinoisAges 19–85 - NCT07349160RecruitingEarly Phase 1
Metabolically armed TIL therapy for advanced solid tumors
This trial tests a new cell therapy called Meta10-TIL, where immune cells from your tumor are modified and given back to you to help fight cancer. It is for people with advanced solid tumors that have not responded to standard treatments.
BeijingAges 19–70 - NCT07339332RecruitingEarly Phase 1
CAR-T cell therapy for moderate to severe lupus
This study tests whether a new CAR-T cell treatment (called CT1195E) can help people with lupus that hasn't improved with standard medicines. CAR-T cells are specially trained immune cells that seek out and destroy certain faulty immune cells, which may reduce lupus symptoms. The trial is for people with moderate to severe active lupus affecting organs like the kidneys, heart, or blood system.
Wuhan, HubeiAges 18–65 - NCT07222787Recruiting
Testing a new spinal implant for lower back fusion
This trial tests a new spinal implant system (CORUS-LX) for fusing two lower back discs that are causing pain. It is meant for people with severe, long-lasting back or leg pain that hasn't improved with non-surgical treatments.
Scottsdale, ArizonaAges 18–80 - NCT06946394RecruitingPhase 4
Switching anemia medicine for kidney disease patients
This trial tests a new medicine called pegmolesatide for people with chronic kidney disease and anemia. It compares switching to this new medicine versus staying on current treatments, to see if it is safe and works well.
Dalian, LiaoningAges 18–80 - NCT04294927Recruiting
Tube removal first, then ovaries later for high-risk women
This study looks at whether removing the fallopian tubes first, and the ovaries later, is safe for women with certain inherited gene mutations that raise ovarian cancer risk. It may help you understand a prevention approach when you’re considered high risk and have finished having children.
Chicago, IllinoisAges 25–50 - NCT07636824RecruitingPhase 2
Chemotherapy plus radiation after bile duct cancer surgery
This study tests whether combining chemotherapy and radiation therapy after surgery improves outcomes for patients with bile duct or gallbladder cancer. It's designed for patients whose surgery showed signs the cancer might come back.
BeijingAges 18–80 - NCT06876831Recruiting
Lung cancer screening for current and recent smokers
This study aims to create a program to help people get screened for lung cancer while they are in the hospital. It is for people who are at higher risk due to their age and smoking history.
New York, New YorkAges 50–80 - NCT05610566Recruiting
HighLife valve replacement for severe leaking mitral valve
This trial studies a new catheter-based valve replacement system for people with moderate to severe, or severe, mitral valve regurgitation (a leaky mitral valve). It aims to check whether the procedure is safe and can improve heart function compared with expected care.
Suzhou, JiangsuAges 18 years+ - NCT06368882RecruitingPhase 4
Peg-interferon for hepatitis B with fatty liver
This trial tests a medicine called peg-interferon for people who have both chronic hepatitis B and fatty liver. It aims to see if the treatment is safe and effective in helping your body fight the hepatitis B virus.
NingboAges 18–60 - NCT07361224RecruitingPhase 1
Combining CLS-015 with CAR-T for large B-cell lymphoma
This trial tests combining an experimental drug (CLS-015) with a standard CAR-T cell therapy for people with large B-cell lymphoma whose disease is stable or progressing. It aims to see if the combination is safe and might improve treatment outcomes.
Tel AvivAges 18 years+ - NCT07120282RecruitingPhase 2
Tislelizumab after surgery for early-stage lung cancer
This trial tests whether a drug called tislelizumab, given after surgery, can help prevent lung cancer from coming back. It is for people with stage I non-small cell lung cancer who have certain high-risk features and a protein called PD-L1 on their tumor cells.
BeijingAges 18 years+ - NCT06817954Recruiting
Breast reconstruction after mastectomy for breast cancer
This trial tests how safe and effective it is to remove the breast (mastectomy) and rebuild it right away during the same surgery. It is for women with early-stage breast cancer who want reconstruction instead of breast-sparing surgery.
Nanjing, JiangsuAges 18–75 - NCT06277024Recruiting
Combination therapy for advanced HER2-negative stomach cancer
This trial tests a combination of immunotherapy (candenizumab), a targeted therapy (lenvatinib), and chemotherapy (SOX regimen) for advanced HER2-negative stomach or gastroesophageal junction cancer that has not been treated before. The goal is to see if this combination is safe and works better than standard treatments.
Fuzhou, FujianAges 18–75 - NCT07656753RecruitingEarly Phase 1
Gene therapy trial for RLBP1-related retinal dystrophy
This trial tests an injection (PUMCH-E111) for people with a specific genetic form of inherited retinal dystrophy caused by RLBP1 mutations. It aims to see if the treatment is safe and can help preserve vision.
Beijing, Beijing MunicipalityAges 18–55 - NCT07551037RecruitingPhase 1
Immune Therapy to Prevent AML Relapse After Chemotherapy
This trial tests a new type of maintenance therapy for acute myeloid leukemia (AML) patients who have already responded well to chemotherapy. The treatment uses your own immune cells to help prevent the cancer from coming back.
Fuzhou, FujianAges 18–70 - NCT07548697RecruitingEarly Phase 1
Safety study of CT1182 for relapsed B-cell lymphoma
This early-stage trial tests a new drug called CT1182 for B-cell non-Hodgkin lymphoma that has come back or stopped responding to prior treatment. The study will measure how safe the drug is, how well it works, and how your body processes it.
Wuhan, HubeiAges 18–75
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Common questions
- Are there clinical trials for medication safety?
- Yes. Clin2 currently lists 383 recruiting medication safety studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a medication safety trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a medication safety trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.