Clinical trials
Mitral Regurgitation clinical trials
Below are recruiting mitral regurgitation clinical trials, each written for real people, not researchers. We’re tracking 100 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06917664RecruitingPhase 4
Treating moderate mitral regurgitation in heart surgery patients
This trial looks at how to treat moderate mitral regurgitation (a leaky heart valve) in people who are already having coronary artery bypass surgery (CABG). It aims to find the best way to manage this condition to improve heart function.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06883864Recruiting
Ablation for leaky valve with constant atrial fibrillation
This study tests whether a catheter ablation procedure (a way to fix abnormal heart rhythms) can help people who have both constant atrial fibrillation and severe mitral regurgitation (a leaky heart valve). It is for people whose heart valve leak is caused by the rhythm problem, not by valve damage.
Hefei, AnhuiAges 18–80 - NCT07131631Recruiting
MitraClip for leaky heart valve in heart failure patients
This trial tests if the MitraClip device helps people with heart failure and a leaky mitral valve. It uses a special MRI to check how the heart responds to treatment.
Minneapolis, MinnesotaAges 18 years+ - NCT06780241Recruiting
Sex differences in valvular heart disease
This study uses special MRI scans to look at how valvular heart disease (like leaky or narrowed aortic valves) affects men and women differently. It aims to find unique biological patterns that could lead to better treatments.
Cleveland, OhioAges 18–90 - NCT07085650Recruiting
Atrial Fibrillation Ablation Study
This study is for people with atrial fibrillation who are planning to have a catheter ablation procedure. It will look at how well the heart works after the procedure and how to prevent future events.
Shenyang, LiaoningAges 18 years+ - NCT04898335Recruiting
Tendyne heart valve registry for real-world patient experiences
This registry collects information from people who received the Tendyne mitral valve in routine care. It helps doctors understand how the valve performs in everyday practice and may guide future care.
LinzAges 18 years+ - NCT07605715Recruiting
Catheter vs. Surgery for Leaky Mitral Valve
This study compares two ways to fix a leaky mitral valve (a heart valve that doesn't close properly): one using a thin tube inserted through blood vessels (catheter) versus traditional open-heart surgery. The goal is to see which approach works better and is safer for older adults.
Los Angeles, CaliforniaAges 60 years+ - NCT05061004Recruiting
Cephea valve study for severe mitral valve disease
This study tests a new device called the Cephea valve, which is placed through a small tube (catheter) to treat severe leaking or narrowing of the mitral valve. It may be an option for people who are not good candidates for open-heart surgery.
Phoenix, ArizonaAges 18 years+ - NCT03142152Recruiting
Mitral valve implant for heart failure with leaky mitral valve
This trial tests whether a device called the Carillon Mitral Contour System can help people with heart failure caused by a mild-to-moderate leaky mitral valve. You’d be compared against a control group, and the goal is to improve heart failure symptoms and outcomes.
Gilbert, ArizonaAges 18 years+ - NCT07055919Recruiting
Assist system for mitral valve clip procedure
This study is testing a new assist system to help doctors perform a minimally invasive procedure (MitraClip) that clips the leaky mitral valve without open-heart surgery. It is for people with severe mitral regurgitation who cannot safely have surgery or choose not to.
Xiamen, FujianAges 18 years+ - NCT06836011Recruiting
Heart valve leakage study in a type of amyloid heart disease
This study looks at how common and how serious heart valve leaks are in people with transthyretin amyloid cardiomyopathy (a condition where abnormal protein builds up in the heart). The goal is to better understand these leaks and how they affect long-term health.
Graz, StyriaAges 18 years+ - NCT07450911RecruitingPhase 1
Mitral valve replacement with the ReValve system
This study is for people with severe mitral valve leakage (mitral regurgitation) who may need a valve replacement. It tests whether the ReValve system is safe and can help improve symptoms and heart function.
TbilisiAges 18 years+ - NCT04761120Recruiting
Follow-up study for specific heart valve repair ring implants
This study follows people who are going to get certain types of heart valve repair rings or bands. It aims to track safety and outcomes after the Abbott device is implanted in routine care over follow-up visits.
Durham, North CarolinaAges 18 years+ - NCT03958773Enrolling by invitation
Transcatheter treatment for severe leaking mitral valve
This study tests a new catheter-based system to treat severe mitral valve leaking when open-heart surgery is considered high risk. It may help improve blood flow and symptoms by repairing the valve without open surgery, using ultrasound guidance and follow-up visits to track safety and results.
KaunasAges 18 years+ - NCT02996552Recruiting
Ring repair for mild-to-moderate leaky right valve
This trial looks at whether adding a specific repair to the right valve (called tricuspid annuloplasty) during mitral valve surgery helps people whose right valve leakage is not severe. It compares doing the extra right-valve repair versus doing only the mitral valve repair.
Rozzano, MilanoAges 18 years+ - NCT07796659Recruiting
Early study of a new implant for leaking heart valve
This study tests a new device called the MRace implant that is designed to repair a leaky mitral valve without open-heart surgery. It may help people with severe leakage who are at high risk for traditional surgery.
TbilisiAges 18 years+ - NCT06113354Recruiting
Testing the MRace implant for leaky heart valve repair
This trial tests a new device called MRace that may fix a leaky mitral valve without open-heart surgery. It's for people whose valve leaks severely and who can't have standard surgery due to other health issues.
Porto Alegre, Rio Grande do SulAges 18 years+ - NCT06600191Recruiting
New mitral valve study for leak repair
This trial tests a new device called the Capstan system to fix a leaky mitral valve (mitral regurgitation) without open-heart surgery. It may help people whose valve leak is moderate to severe and still have symptoms despite medicines.
MelbourneAges 18 years+ - NCT02245763Recruiting
Mitral valve procedure registry for patients who can take blood thinners
This is a study that collects medical information about people having a mitral valve procedure, to better understand outcomes. It may help because it improves how doctors choose and manage care for mitral valve problems.
Washington D.C., District of ColumbiaAges 1 year+ - NCT06282042Recruiting
Early Fix of Leaky Mitral Valve After Heart Attack
This trial tests an early, minimally invasive procedure to fix a leaky mitral valve using a catheter (a thin tube) after a heart attack. The goal is to see if fixing the valve early can help patients recover better and avoid more serious heart problems.
Afula, AfulaAges 18–99 - NCT07188233Recruiting
Catheter repair for leaky mitral valve in heart failure
This trial tests a new device (CathHELIX) placed through a vein to repair a leaky mitral valve in people with heart failure. It is for people with moderate to severe mitral regurgitation who still have symptoms despite medical therapy.
Tbilisi, GeorgiaAges 18 years+ - NCT06075823Recruiting
Mitral valve repair for heart failure with ATTR amyloidosis
This trial tests a clip procedure to fix a leaky heart valve in people who also have a heart condition called ATTR-CM, which can cause heart failure. The clip is placed without open-heart surgery to help improve symptoms and quality of life.
GrazAges 18 years+ - NCT07741383Recruiting
Combined procedure for severe mitral regurgitation and atrial fibrillation
This study tests whether combining a valve repair procedure with a heart rhythm reset procedure is safe and effective for people with severe mitral regurgitation and atrial fibrillation. It may help improve heart function and reduce symptoms.
Hangzhou, ZhejiangAges 18 years+ - NCT06552689Recruiting
Testing Sutra Hemi-valve for leaky mitral valve
This trial tests a new, less invasive heart valve (Sutra Hemi-valve) for people with a leaky mitral valve who cannot have standard surgery. The valve is delivered through a vein in your leg, so you avoid open-heart surgery.
HamiltonAges 18 years+
Hear when a new Mitral Regurgitation trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for mitral regurgitation?
- Yes. Clin2 currently lists 100 recruiting mitral regurgitation studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a mitral regurgitation trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a mitral regurgitation trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.