Clinical trials
Muscle clinical trials
Below are recruiting muscle clinical trials, each written for real people, not researchers. We’re tracking 1,161 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06500390Recruiting
TMD and levonorgestrel IUD use study
This study looks at whether using a levonorgestrel intrauterine device (a hormone-releasing IUD) for at least 3 months is linked to jaw joint problems (temporomandibular disorder). It may help women understand potential side effects of this birth control method.
Istanbul, MaltepeAges 18–45 - NCT06503172RecruitingPhase 2
Job's Tear for muscle health in older adults
This trial tests if whole grain Job's Tear can improve muscle health, blood sugar, and cholesterol in people aged 60-95 who may feel weak or have slowed down. It looks at whether adding this grain to your diet helps with daily energy and walking speed.
TaipeiAges 60–95 - NCT06503523Recruiting
Brain activity during pain and itch
This study tests whether imagining movements changes brain activity when you feel pain or itch. It could help scientists understand how the brain responds to these sensations.
GistrupAges 18–60 - NCT06511765RecruitingPhase 3
Nerve block for acute lower back pain: a pilot study
This study tests whether a single injection of a numbing medicine (ropivacaine) into the muscles of the lower back can quickly relieve sudden, severe back pain that has lasted less than a week. The goal is to see if this nerve block can help when standard pain pills aren't working.
Saint-HerblainAges 18 years+ - NCT06525571RecruitingPhase 3
Blue light surgery for high-risk bladder cancer
This trial tests if using blue light during surgery helps remove all cancer in people with high-risk non-muscle invasive bladder cancer. It may lower the chance of the cancer coming back.
Washington D.C., District of ColumbiaAges 18 years+ - NCT06534788Recruiting
Comparing two muscle therapies for piriformis syndrome
This study tests two different hands-on therapy techniques (reciprocal inhibition and post-facilitation muscle energy) along with standard physical therapy to see which works better for relieving piriformis syndrome—a condition that causes deep buttock pain. You may benefit if you have chronic hip/buttock pain and a shortened piriformis muscle.
Rawalpindi, Punjab ProvinceAges 20–50 - NCT06535815Recruiting
Cyclic daytime feeding with ketogenic nighttime fasting for ICU patients
This trial tests a special feeding schedule where ICU patients receive nutrition during the day and fast at night, which may help their recovery. It aims to see if this approach is safe and beneficial.
Cologne, North Rhine-WestphaliaAges 18 years+ - NCT06537154RecruitingPhase 2/Phase 3
Neoadjuvant therapy for bladder cancer with active surveillance
This trial tests whether people with muscle-invasive bladder cancer can safely avoid immediate surgery or radiation after a short course of chemotherapy. Instead, they would be closely monitored and only treated if the cancer comes back.
Vancouver, British ColumbiaAges 19 years+ - NCT06538974Recruiting
Long-term use of an exoskeleton for leg weakness
This trial tests a walking device called an exoskeleton to help people with leg weakness or movement problems. It's designed to see if using the exoskeleton regularly over time can help improve walking or mobility.
ParisAges 18 years+ - NCT06541548Recruiting
Bone health study for bone and muscle loss conditions
This study uses special imaging to compare bone structure in people with conditions that cause bone or muscle loss vs. those with back pain. It aims to better understand bone health in different diseases.
Saint-EtienneAges 18 years+ - NCT06543420Recruiting
Pelvic muscle repair to improve bladder control after prostate surgery
This trial is testing a new surgical technique to help the muscles that support the bladder recover after prostate cancer surgery. It may help men who are having robot-assisted prostate removal to regain better bladder control afterward.
Beijing, Beijing MunicipalityAges 18–80 - NCT06547684Recruiting
Shock wave therapy for foot stiffness after stroke
This trial tests whether shock wave therapy can help relax the tight calf muscles that cause foot drop after a stroke. It may help you walk better and reduce foot stiffness.
Vila-real, CastellonAges 18 years+ - NCT06551233RecruitingPhase 1
Testing a new drug for high-risk bladder cancer
This trial tests a new drug called 9MW2821 for people with high-risk bladder cancer that hasn't grown into the bladder muscle. It's for those who have already tried other treatments that didn't work or who can't have standard therapy.
Nanjing, JiangsuAges 18 years+ - NCT06554132Recruiting
Breathing Muscle and Exercise Capacity in Scleroderma
This study looks at how scleroderma affects breathing muscles and exercise ability. You'll do some simple breathing tests and ride a stationary bike to see how your body responds.
ElâzığAges 18–65 - NCT06566066Recruiting
Thyroid hormone resistance patient registry
This study creates a registry for people with thyroid hormone resistance caused by specific genetic mutations. It helps doctors collect data to better understand and treat the condition.
BerlinAges Any age - NCT06567743RecruitingPhase 2
Study of a new virus therapy for high-risk bladder cancer
This trial tests a new virus-based medicine, cretostimogene grenadenorepvec, given directly into the bladder for people with high-risk non-muscle-invasive bladder cancer. It may help prevent the cancer from coming back, especially for those who have not had BCG treatment or whose cancer did not respond to BCG.
Phoenix, ArizonaAges 18 years+ - NCT06573086Recruiting
Resistance training, detraining, and retraining
This study looks at how your body responds to resistance training, a break from training, and then training again. It is for healthy adults who already completed a previous exercise study.
Jyväskylä, Central FinlandAges 18–50 - NCT06574737Recruiting
Can muscle signals predict arm recovery after stroke?
This study tests whether a simple muscle signal test (called surface EMG) can predict how well your arm will recover after a stroke. It involves placing small stickers on your skin to measure muscle activity while you try to move your affected arm.
Bandung, West JavaAges 18 years+ - NCT06584851Recruiting
3D muscle study in children with cerebral palsy
This study uses a special 3D microscope to look at muscle structure in children with cerebral palsy. It aims to understand muscle stiffness by comparing tiny muscle samples taken during a scheduled procedure that already requires general anesthesia.
Leuven, Vlaams-BrabantAges 2–9 - NCT06587165Recruiting
Measuring new heart cells in babies having heart surgery
This study looks at how the heart makes new muscle cells in babies under 1 year old who need heart surgery. Tissue that is normally removed during surgery will be studied to learn more about heart repair.
New York, New YorkAges 4 weeks–1 year - NCT06598982Recruiting
Muscle Weakness in the Breathing Muscles in Scleroderma
This study looks at whether people with systemic sclerosis (scleroderma) have weakness in the muscles they use to breathe. It aims to find out if measuring these muscles can help detect early breathing problems.
Konya, SelcukluAges 18–75 - NCT05518188RecruitingPhase 1/Phase 2
Gene therapy trial for a childhood AP4M1 brain disorder
This trial studies a one-time gene therapy meant to help children with SPG50 disease caused by changes in the AP4M1 gene. Researchers will give the treatment and closely monitor safety and early signs of benefit.
Dallas, TexasAges 4 months–10 years - NCT06602141Recruiting
Exercise and fat cell changes study
This study looks at how endurance exercise changes fat cells in the body. It may help understand how exercise benefits weight-related health.
Orlando, FloridaAges 18–45 - NCT06604793Recruiting
Creatine supplement study for young adults
This study tests whether taking creatine supplements affects muscle function in healthy young adults who are not currently doing resistance training. It may help understand if creatine can benefit people new to exercise.
Regina, SaskatchewanAges 18–39
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Common questions
- Are there clinical trials for muscle?
- Yes. Clin2 currently lists 1,161 recruiting muscle studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a muscle trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a muscle trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.