Clinical trials
Neuropathy, Painful clinical trials
Below are recruiting neuropathy, painful clinical trials, each written for real people, not researchers. We’re tracking 65 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04699734Recruiting
Nerve block for nerve pain from diabetes
This trial studies whether a numbing “nerve block” can reduce long-lasting nerve pain caused by diabetic neuropathy. You may keep your usual pain medicines, and the study will mainly check whether you fit the safety and diagnosis criteria.
Aarhus N, JutlandAges 18 years+ - NCT05483816Recruiting
Sensory stimulation trial for nerve pain in people with neuropathy
This study tests a multi-sensory (multiple-sense) stimulation approach to see if it can help people with nerve-related pain in the legs/feet. You must be able to safely take part in MRI-related sessions and answer questions about pain and health history.
Zurich, Canton of ZurichAges 18–80 - NCT06614322RecruitingPhase 2
Testing Pain Sensitivity and Pain Relief for Nerve Pain in Feet
This study looks at how people with long-term nerve pain in their feet respond to pain relief. It aims to match the right treatment to each person based on their pain sensitivity.
Boston, MassachusettsAges 18–80 - NCT07250828Enrolling by invitation
BurstDR spinal cord stimulation for painful diabetic neuropathy
This trial tests a type of spinal cord stimulation called BurstDR to see if it can reduce pain from diabetic nerve damage. It may help people with diabetes who have ongoing leg pain that hasn't gotten better with standard pain medications.
Grand Island, NebraskaAges 19 years+ - NCT07509671Recruiting
Can a diet help painful diabetic nerve pain?
This study tests whether a special diet can help reduce pain caused by nerve damage from Type 2 diabetes or prediabetes. You may qualify if you have painful diabetic neuropathy and are looking for a non-medication approach.
Hendersonville, North CarolinaAges 18 years+ - NCT04678895RecruitingPhase 2
Low-dose naltrexone for nerve pain from diabetes
This Phase 2 trial studies whether a low dose of naltrexone can reduce painful nerve pain caused by diabetes. It may help people whose diabetic nerve pain did not improve with at least one standard treatment.
Lebanon, New HampshireAges 18 years+ - NCT07743073Recruiting
Ceylon cinnamon for diabetic nerve pain
This study tests whether taking Ceylon cinnamon daily can help lower blood sugar, improve cholesterol, and reduce nerve pain in adults with type 2 diabetes and painful diabetic peripheral neuropathy. If you qualify, you might get a natural supplement that could ease your symptoms.
AmmanAges 18 years+ - NCT05754190Recruiting
Smartphone study of mood and symptoms in people with pain
This study uses a smartphone app to track daily pain and mood changes over about 4 months. It’s meant to learn patterns that could help better understand how mood and pain affect each other.
Providence, Rhode IslandAges 18 years+ - NCT06912646Recruiting
Laser therapy for foot pain from idiopathic neuropathy
This trial tests a laser device for temporary relief of foot pain from peripheral neuropathy when the cause is unknown. It may help if you have constant foot pain and are not diabetic.
Miramar, FloridaAges 22 years+ - NCT07061769Enrolling by invitation
Using a gentle head device to help with nerve pain from chemo
This trial tests a low-intensity cranial PEMF device to see if it can reduce nerve pain caused by chemotherapy. Participants use the device at home and receive text messages to track their symptoms.
Newport Beach, CaliforniaAges 18–60 - NCT06848348RecruitingPhase 2
Halneuron for chemotherapy-induced nerve pain
This trial tests whether the drug Halneuron can safely reduce nerve pain caused by common chemotherapy drugs (platinum and taxane). It is for people whose nerve pain started after chemotherapy and whose cancer is not currently getting worse.
Sheffield, AlabamaAges 18 years+ - NCT07260656RecruitingEarly Phase 1
Capsaicin cream for diabetic nerve foot pain
This trial tests a new cream (Capsadyn®) made from chili pepper extract to see if it can reduce nerve pain in the feet caused by diabetes. If it works, it could offer a simple treatment you apply at home.
Roanoke, VirginiaAges 25–75 - NCT04970121RecruitingPhase 2
Duloxetine for chemotherapy nerve pain in solid tumor patients
This Phase 2 trial tests duloxetine to see if it safely reduces painful nerve damage caused by chemotherapy (especially taxanes) in people with solid tumors. If you have moderate-to-severe nerve pain and meet lab and heart-safety checks, this study may be an option.
Bengbu, AnhuiAges 18–75 - NCT06480786Recruiting
Spinal cord stimulator for diabetic nerve and artery pain
This study tests if a spinal cord stimulator (a device that sends mild electrical pulses to the spine) can relieve severe leg pain caused by diabetic nerve damage and poor blood flow. It may help people who have not found enough relief from other treatments.
Omaha, NebraskaAges 19–89 - NCT06471517Recruiting
Nerve device for diabetic foot numbness
This trial tests a special device that uses mild electrical pulses to help improve problems caused by diabetic nerve damage, such as numbness and pain in the feet. If you have diabetic neuropathy and can walk on your own, this study may be a good option.
BelgradeAges 18 years+ - NCT06443281Recruiting
Understanding pain after spinal cord injury or nerve damage
This study is looking at how people with spinal cord injuries or peripheral neuropathy (nerve damage outside the spine) experience pain. The goal is to better understand the different types of pain, which could help doctors create more personalized treatments in the future.
Zurich, Canton of ZurichAges 18–80 - NCT07301177Recruiting
Magnetic stimulation for veterans with nerve pain after injury
This study tests whether a non-invasive magnetic stimulation treatment can help veterans with long-term nerve pain after an injury or surgery. It may offer a drug-free option to reduce pain and improve quality of life.
San Diego, CaliforniaAges 18 years+ - NCT04299893RecruitingPhase 2/Phase 3
Ozone treatment for chemotherapy nerve pain
This trial tests whether ozone therapy can reduce painful nerve damage caused by chemotherapy. It is for adults with ongoing moderate-to-severe pain in the hands or feet after chemotherapy.
Las Palmas de Gran Canaria, Las PalmasAges 18–100 - NCT07639060Recruiting
Pain Relief Study Using Freezing Nerve Treatment
This study watches how well a freezing procedure works for chronic pain over 6 to 12 months. Your doctor thinks this procedure could help your pain, and the study simply tracks your recovery through questionnaires to help doctors understand if it works.
Old Saybrook, ConnecticutAges 18 years+ - NCT07712913RecruitingPhase 3
Pregabalin for nerve pain from diabetes or shingles
This trial tests an extended-release version of pregabalin (a pain medication) for people with long-term nerve pain caused by diabetes or shingles. It aims to see if this once-daily pill can reduce pain with fewer side effects.
Salvador, Estado de BahiaAges 18–75 - NCT07210203Recruiting
Nerve gliding for pain, balance, and quality of life in diabetic nerve damage
This study tests whether adding nerve gliding exercises (neural mobilization) to usual care can reduce pain, improve balance, and enhance quality of life for people with diabetic peripheral neuropathy. It may help if you have mild to moderate nerve pain and are between 50 and 75 years old.
IslamabadAges 50–75 - NCT06603792RecruitingEarly Phase 1
Neurofeedback for diabetic nerve pain
This trial tests whether a brain-training technique called neurofeedback can help reduce nerve pain caused by diabetes. It is for people with type 1 or type 2 diabetes who have had moderate-to-severe nerve pain for at least 3 months.
OdenseAges 18–82 - NCT07195045Recruiting
Thai PainPREDICT validation study for diabetes nerve pain
This study tests a tool (PainPREDICT) to predict nerve pain in people with diabetes. It aims to identify those at risk so treatment can start early.
Pathum Wan, BangkokAges 18 years+ - NCT06158529Recruiting
High-frequency spinal cord stimulation for diabetic nerve pain
This trial tests if a special type of spinal cord stimulation (high-frequency SCS) can better relieve painful nerve damage caused by diabetes. If you have long-term burning, stabbing, or electric-shock-like pain in both legs, this treatment may help reduce that pain.
BeijingAges 18–80
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Common questions
- Are there clinical trials for neuropathy, painful?
- Yes. Clin2 currently lists 65 recruiting neuropathy, painful studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a neuropathy, painful trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a neuropathy, painful trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.