Clinical trials
Obese Adults clinical trials
Below are recruiting obese adults clinical trials, each written for real people, not researchers. We’re tracking 150 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06640179Recruiting
Lifestyle program for kidney transplant recipients
This study tests a diet and exercise program for people who recently received a kidney transplant. It aims to see if the program is safe and helpful for improving health after transplant.
Kansas City, KansasAges 18 years+ - NCT07282743RecruitingPhase 2
Study of GL0034 for overweight or obese adults with type 2 diabetes
This trial tests a new medication, GL0034, to see if it helps with weight loss and blood sugar control in people with type 2 diabetes who are overweight. Participants must already be taking metformin and not using other diabetes drugs.
Little Rock, ArkansasAges 18 years+ - NCT07732426Recruiting
Semaglutide and brain response to food in obesity with food addiction
This trial tests if semaglutide can change how your brain responds to food cues, like seeing or smelling food, in people with obesity and a tendency toward food addiction. It may help understand why some people struggle with overeating and how this medication could help.
SeoulAges 19–50 - NCT05713448Recruiting
Check how common overweight is in adults with type 1 diabetes
This study looks at how many adults with type 1 diabetes have overweight or obesity. It may help improve future care planning for people living with type 1 diabetes.
LeuvenAges Any age - NCT06937203RecruitingPhase 1/Phase 2
A new obesity drug study for people with or without type 2 diabetes
This early-stage study tests an investigational drug called ARO-ALK7 to see if it helps adults with obesity lose weight. It includes people who have type 2 diabetes as well as those who do not, and requires that you have tried to lose weight with lifestyle changes in the past.
Morayfield, QLCAges 18–65 - NCT06700538RecruitingPhase 1/Phase 2
Study of an experimental drug for obesity with or without type 2 diabetes
This study tests an experimental medication called ARO-INHBE in adults with obesity, including those who also have type 2 diabetes. The goal is to see if it helps with weight loss and is safe.
Grafton, AucklandAges 18–65 - NCT07215559RecruitingPhase 2
Study of new drugs for obesity with type 2 diabetes
This trial tests two new medicines, alone or together, to see if they help with weight loss and blood sugar control in adults who have type 2 diabetes and are overweight or have obesity.
Gilbert, ArizonaAges 18–75 - NCT05843318Recruiting
Water intake and weight control for adults 50+
This study tests whether adjusting how much plain drinking water you drink can help with weight control in older adults. You may be asked to follow a structured plan and participate in activities as part of the research.
Blacksburg, VirginiaAges 50 years+ - NCT07715955Recruiting
Can probiotics help control appetite in adults with overweight or obesity?
This study tests whether taking probiotics can help regulate appetite in people who are overweight or have obesity. It aims to understand if these supplements can support weight management by affecting hunger and fullness signals.
Maastricht, LimburgAges 20–70 - NCT07575932RecruitingPhase 2
Testing New Weight Loss Medications PF-08653945 and PF-08653944
This study tests two new experimental medications designed to help adults lose weight and improve weight-related health conditions like high blood pressure and sleep apnea. Participants will take one of these medications to see if it's safe and effective.
Chandler, ArizonaAges 18 years+ - NCT07220772RecruitingPhase 3
A drug for severe obesity caused by leptin gene mutations
This trial tests a new drug called mibavademab for people with severe obesity caused by changes in the leptin (LEP) gene. It aims to see if the drug can help with weight loss in children, teens, and adults who have this rare genetic condition.
UlmAges 2 years+ - NCT07594093RecruitingPhase 1
A study of REGN20934 for adults with overweight or obesity
This trial tests a new medication, REGN20934, to see how safe it is and how it works in the body for adults who are overweight or have obesity. It may help if you are looking for new treatment options.
Glendale, CaliforniaAges 18–65 - NCT06996431Enrolling by invitation
Weight loss program with mobile health support
This study tests a new way to help adults lose weight using a smartphone app and health coaching. You might qualify if you are overweight, live in Hong Kong, speak Chinese, and can walk without help.
Hong KongAges 18 years+ - NCT07654374RecruitingPhase 3
Study of a new pill for weight loss and diabetes
This study tests a new daily pill (aleniglipron) to help adults with excess weight and type 2 diabetes lose weight and improve blood sugar control. It may be a good fit if you have a BMI of 27 or higher and your diabetes is managed with A1c between 6.5% and 10%.
Birmingham, AlabamaAges 18–79 - NCT06321458Recruiting
Intensive weight loss program vs. usual care for obesity
This trial compares an intensive weight loss program to usual care for adults with severe obesity and related health problems. It aims to see if a structured program helps people lose more weight and improve their health.
FrederiksbergAges 18–60 - NCT07151105Recruiting
Vitamin C for gut health in adults with obesity
This trial tests whether taking vitamin C supplements helps improve gut barrier function in adults with obesity. You'll follow a low-fruit-and-vegetable diet for two, two-week periods.
Columbus, OhioAges 18–50 - NCT07539415RecruitingPhase 1
Safety and effectiveness study of new injection in healthy adults
This study tests a new experimental injection in healthy volunteers to see if it's safe and how well the body absorbs it. Researchers will compare it with other similar treatments to understand how it works.
SeoulAges 19–64 - NCT06265246Recruiting
Milk and yogurt for stronger bones in young adults
This study tests whether adding milk and yogurt to your diet can improve bone health and body composition. If you're a young adult with low calcium intake, you may qualify to join.
Saskatoon, SaskatchewanAges 19–30 - NCT07675590RecruitingPhase 1
Safety study of TIX100 in healthy volunteers
This study tests a new oral medication called TIX100 in healthy people to see if it is safe and how the body handles it. It is the first step in human testing, so it focuses on safety and side effects.
Chula Vista, CaliforniaAges 18–70 - NCT06893016RecruitingPhase 3
Study of RAY1225 for adults with obesity or overweight
This trial tests a new medicine called RAY1225 to help people lose weight. If you have obesity or are overweight with related health conditions, you may be able to join.
BeijingAges 18 years+ - NCT07523672Enrolling by invitation
Care Model for Sarcopenic Obesity in Older Adults
This trial tests a new care approach for older adults who have both excess body fat and muscle loss (sarcopenic obesity). The goal is to help improve muscle strength, physical function, and body composition.
Nakhon Nayok, Changwat Nakhon NayokAges 60 years+ - NCT07247084RecruitingPhase 4
Tirzepatide for weight loss in adults with obesity
This trial tests if tirzepatide is more effective than standard obesity treatments for adults who have a BMI between 30 and 35 and one weight-related health condition, but do not have diabetes. The goal is to help you lose weight.
AltrinchamAges 18 years+ - NCT07341841Enrolling by invitation
Obesity risk factors study in adults
This study looks at how genes and lifestyle affect obesity risk. It includes adults aged 18 to 70 with different weight levels, from overweight to severe obesity.
Augusta, GeorgiaAges 18–70 - NCT06636058Recruiting
Digital treatment for weight and mood in adults 50+
This study tests a digital program that helps with weight loss and depression at the same time. It is designed for Black, Hispanic, and other adults over 50 who carry extra weight and feel down.
Chicago, IllinoisAges 50–74
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Common questions
- Are there clinical trials for obese adults?
- Yes. Clin2 currently lists 150 recruiting obese adults studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a obese adults trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a obese adults trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.