Clinical trials · Philadelphia, PA
Obesity clinical trials in Philadelphia
We’re tracking 42 recruiting obesity studies with a site in or near Philadelphia — including Phase 1/Phase 2, Phase 2 and Phase 3 studies, each written for real people, not researchers.
Recruiting studies near Philadelphia
- NCT07339423RecruitingPhase 3
A study of a new medicine for weight loss
This study tests a new medicine to see how well it helps people with excess body weight lose weight. It may be an option if you have tried to lose weight through dieting before but haven't had lasting success.
Philadelphia, PennsylvaniaAges 18 years+ - NCT06111040Recruiting
Parenting study for food-driven young children
This study tests a program to help parents handle feeding their 4- or 5-year-old child who is very motivated by food. It aims to support healthy eating habits.
Philadelphia, PennsylvaniaAges 4–5 - NCT07202884RecruitingPhase 3
Orforglipron for Women with Stress Incontinence and Overweight
This study tests an oral medication called orforglipron to see if it helps women with stress urinary incontinence who are also overweight or have obesity. The medicine may reduce leaking episodes and also help with weight loss.
Philadelphia, PennsylvaniaAges 18 years+ - NCT06147973Recruiting
Healthy lifestyle program for teen girls
This study tests a healthy lifestyle program that helps teen girls accept their bodies and make positive changes. It aims to see if this approach can improve weight-related health and well-being.
Philadelphia, PennsylvaniaAges 14–19 - NCT07639021RecruitingPhase 2
Testing Different Dose Schedules of a New Weight Loss Medicine
This study tests a new injectable medication (NNC0662-0419) designed to help people with obesity lose weight. Researchers are comparing different ways of increasing the dose to find the safest and most effective approach.
Philadelphia, PennsylvaniaAges 18 years+ - NCT06937099RecruitingPhase 3
Testing two drugs for Crohn's with weight issues
This trial tests two study drugs, mirikizumab and tirzepatide, in people with moderate to severe Crohn's disease who also have overweight or obesity. The goal is to see if these treatments can help control Crohn's symptoms and inflammation.
Philadelphia, PennsylvaniaAges 18–70 - NCT06299891RecruitingPhase 2
Study of weight loss medication for youth with hypothalamic obesity
This study tests a combination of two medications, phentermine and topiramate, to see if they help young people with hypothalamic obesity lose weight safely. Hypothalamic obesity is rapid weight gain caused by injury to the hypothalamus, often from a brain tumor or its treatment.
Philadelphia, PennsylvaniaAges 6–28 - NCT06760546RecruitingPhase 3
Testing setmelanotide for weight gain after brain injury
This trial tests a daily injection called setmelanotide to see if it can help people who have gained weight due to a brain injury or condition affecting the hypothalamus. It may help reduce hunger and support weight loss.
Philadelphia, PennsylvaniaAges 4 years+ - NCT07654361RecruitingPhase 3
A new pill for weight loss in obesity and overweight
This study tests an investigational pill called aleniglipron to see if it helps people with obesity or overweight who also have a weight-related health problem (like high blood pressure) lose weight safely. It is a Phase 3 trial, meaning it is in the final stages before seeking approval.
Philadelphia, PennsylvaniaAges 18–79 - NCT06108128Recruiting
Food for thought: thinking skills and eating in children
This study looks at how children's thinking skills (like planning and self-control) affect their eating habits. It may help parents understand how to support healthy eating in young kids.
Philadelphia, PennsylvaniaAges 4–6 - NCT05783765Recruiting
Food, genetics, and behavior study for healthy children
This study looks at how eating, body factors (like weight), and behavior may relate to genetics in healthy children. Your child’s participation could help researchers understand why eating habits differ between families.
Philadelphia, PennsylvaniaAges 5–7 - NCT05082519RecruitingPhase 2
Calorie restriction and exercise to improve leukemia treatment in young patients
This study tests whether a special diet (calorie restriction) and increased physical activity can make chemotherapy work better for young people with B-ALL. Participants will follow a monitored diet and exercise plan during their first month of treatment.
Philadelphia, PennsylvaniaAges 7–25 - NCT05437809Recruiting
Study how people’s brains respond to ultra-processed foods
This study looks at how brain and body reward signals change after eating different ultra-processed foods. It may help researchers understand how food choices and metabolism relate to weight and mood in some people.
Philadelphia, PennsylvaniaAges 18–65 - NCT06914765Enrolling by invitation
Endoscopic sleeve gastroplasty for teens with obesity
This study tests a new, non-surgical procedure called Endoscopic Sleeve Gastroplasty (ESG) to help teenagers with severe obesity lose weight. The goal is to see if it can improve their health and help them reach a healthier weight.
Philadelphia, PennsylvaniaAges 12–17 - NCT05703347Recruiting
Mobile app coaching to improve sleep and prevent childhood obesity
This study tests a mobile health app that helps children get better sleep, aiming to support healthier weight over time. It is designed for children who are getting less sleep than recommended and are in the higher-but-not-highest weight range for their age.
Philadelphia, PennsylvaniaAges 8–12 - NCT07770841RecruitingPhase 3
Oral medication for weight loss study
This study tests an oral medicine (semaglutide) to see if it helps adults with excess weight lose weight. It might offer an easier, pill-based treatment option for weight management.
Philadelphia, PennsylvaniaAges 18 years+ - NCT06292936Recruiting
Remi for weight regain after weight loss surgery
This study tests if the medication Remi can help people who have gained back at least 5% of their lowest weight after gastric bypass or sleeve gastrectomy. It is meant for those who are not currently using other weight loss drugs and are otherwise healthy enough to participate.
Philadelphia, PennsylvaniaAges 18–70 - NCT06817863RecruitingPhase 1/Phase 2
Mobile app for binge eating and weight loss
This study tests a self-guided mobile app (iPhone or Android) to help adults with binge eating and obesity. It aims to see if the app can reduce binge eating episodes and support weight management.
Philadelphia, PennsylvaniaAges 18–70 - NCT07503210RecruitingPhase 3
Study of a new medicine to maintain weight loss
This study tests an investigational medicine to help people who have lost weight keep it off. It's for adults without diabetes who haven't used similar weight-loss drugs before.
Philadelphia, PennsylvaniaAges 18 years+ - NCT06810557Recruiting
Better sleep intervention to prevent obesity in kids
This trial tests a brief sleep program for children ages 6 to 11 who sleep less than 9 hours a night. The goal is to see if improving sleep can help prevent unhealthy weight gain. Eligible families will be randomly assigned to the sleep program or to a comparison group.
Philadelphia, PennsylvaniaAges 6–11 - NCT05748158Recruiting
Study of why weight returns after behavioral weight loss
This study looks at what makes some people regain weight after losing weight in a behavioral weight loss program. You may help researchers understand the role of habits, metabolism, and energy use so better prevention strategies can be developed.
Philadelphia, PennsylvaniaAges 25–59 - NCT05746039RecruitingPhase 1/Phase 2
Testing semaglutide for advanced lung disease
This study checks whether semaglutide is safe and feasible for people with advanced lung diseases and higher body weight. It may help by testing a structured treatment approach, but it includes several health and safety limits.
Philadelphia, PennsylvaniaAges 18–80 - NCT07743450RecruitingPhase 3
Once-daily pill for weight loss in people with type 2 diabetes
This study tests an oral medication, ASC30, to see if it helps people with type 2 diabetes who are overweight or obese lose weight and improve blood sugar control. It is a once-daily pill that may offer a new treatment option.
Philadelphia, PennsylvaniaAges 18 years+ - NCT07743463RecruitingPhase 3
Daily pill for weight loss in adults with overweight or obesity
This trial tests an investigational once-daily pill (ASC30) to see if it can help adults with overweight or obesity lose weight. You may be able to join if you have a high body mass index (BMI) and have tried to lose weight before.
Philadelphia, PennsylvaniaAges 18 years+
Hear when a new Obesity trial opens near Philadelphia, PA
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Obesity trials in other cities
Where these studies are running near Philadelphia
Institutions with a site for the recruiting obesity studies listed above.
- University of Pennsylvania · 7 studies
- Children's Hospital of Philadelphia · 5 studies
- Drexel University · 4 studies
- Temple University Hospital · 4 studies
- ACCOMPLISH Research Site
- AURORA-1 Clinical Site
- AURORA-2 Clinical Site
- Clinical Research of Philadelphia
What taking part in a obesity study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Looking wider? See all recruiting obesity studies in Pennsylvania.
Common questions
- Are there obesity clinical trials near Philadelphia?
- Yes. We're currently tracking 42 recruiting obesity studies with a site near Philadelphia, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a obesity study near Philadelphia?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in Philadelphia to take part?
- Not necessarily. These studies have a site near Philadelphia, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a obesity trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New obesity studies open near Philadelphia regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.