Clinical trials · Tennessee
Obesity clinical trials in Tennessee
We’re tracking 48 recruiting obesity studies with a site in Tennessee — including Phase 1, Phase 1/Phase 2, Phase 2, Phase 3 and Phase 4 studies, each written for real people, not researchers.
Recruiting studies in Tennessee
- NCT06899178RecruitingPhase 2
Atomoxetine for genetic obesity due to MC4R changes
This trial tests a medicine called atomoxetine (Strattera) to help people with a specific genetic form of obesity lose weight. It may be an option if you have a change in the MC4R gene and have not used certain other medications recently.
Nashville, TennesseeAges 6 years+ - NCT06857942RecruitingPhase 4
Tirzepatide added to ixekizumab for psoriasis and weight issues
This trial tests whether adding tirzepatide (a weight-loss and diabetes drug) to ixekizumab (a psoriasis treatment) helps people with moderate-to-severe psoriasis who are overweight or have obesity. It is for those already taking ixekizumab for about 3 months.
Smyrna, TennesseeAges 18 years+ - NCT06802861Recruiting
Aspirin metabolism in pregnant women at risk of pre-eclampsia
This study looks at how pregnant women at risk of pre-eclampsia process aspirin and how it affects their metabolism. Researchers will use blood and urine tests, along with body measurements and surveys, to learn more about how aspirin can help prevent pre-eclampsia.
Knoxville, TennesseeAges 18–45 - NCT06672939RecruitingPhase 3
Orforglipron for Weight Loss in Teens
This study tests a once-daily pill (orforglipron) to help adolescents with obesity or overweight plus related health problems lose weight. It offers a new option for teens who have struggled to lose weight with diet and exercise alone.
Nashville, TennesseeAges 12–17 - NCT06672549RecruitingPhase 3
Weight loss medication study for children with obesity
This trial tests a medication for children and teens with obesity or overweight who have not been able to lose enough weight with diet and exercise alone. It aims to see if a new treatment can help them safely lose weight and improve related health problems.
Nashville, TennesseeAges 6–17 - NCT06654323Recruiting
Behavioral program for childhood obesity
This study tests different levels of a behavioral program to help children with obesity lose weight and live healthier. Families will receive support and guidance over 12 months.
Nashville, TennesseeAges 5–17 - NCT06546696Recruiting
Obesity support program for children and families
This trial offers a 6-month program to help children ages 6–11 with obesity and their parents adopt healthier habits, including exercise and nutrition. It takes place at community centers in Middle Tennessee and provides online training.
Nashville, TennesseeAges 6–12 - NCT06464497Recruiting
Whole foods for teens with obesity pilot study
This study tests whether replacing processed foods with whole foods (like fruits, vegetables, and whole grains) for 8 weeks can help reduce body fat in teens with obesity. Both the teen and a parent or caregiver will learn to prepare and eat healthier meals together.
Nashville, TennesseeAges 10 years+ - NCT06143956RecruitingPhase 2
Weight loss treatments for adults with obesity
This clinical trial tests new treatments for adults who are overweight or have obesity. The goal is to help people lose weight and improve their health.
Nashville, TennesseeAges 18–75 - NCT05312892RecruitingPhase 1/Phase 2
Study for weight-related hormone signals in people with high blood pressure
This early-phase study looks at how the body’s “fight-or-flight” signals may be involved in weight gain (obesity) and high blood pressure. It may help researchers understand the biology and guide future treatments.
Nashville, TennesseeAges 18–65 - NCT05028205Recruiting
Fruit and vegetable voucher program for kids
This trial tests whether giving families vouchers for fruits and vegetables helps improve children’s eating and health. It focuses on children ages 4–10 who have higher body weight for their age and who can participate with an adult caregiver.
Knoxville, TennesseeAges 4–10 - NCT07837973RecruitingPhase 2
Medicine to maintain weight loss after weight-loss shots
This study tests a new medicine called ALV-100 to see if it can help people who have already lost weight with a weight-loss injection or pill keep the weight off. You must be currently on a stable weight-loss medicine and have lost at least 10% of your body weight to join.
Nashville, TennesseeAges 18–75 - NCT07684235RecruitingPhase 3
Long-term study of a weight-loss drug for trial graduates
This study tests a drug called Maridebart Cafraglutide for long-term weight management in people who completed a previous related trial. It looks at how well the drug works and its safety over time.
Knoxville, TennesseeAges 18–99 - NCT07667803RecruitingPhase 3
Study of elecoglipron for weight loss in obesity or overweight
This trial tests an investigational drug called elecoglipron to see if it helps people with obesity or overweight lose weight. It may be an option if you have a high body mass index or weight-related health issues like high blood pressure or prediabetes.
Franklin, TennesseeAges 18 years+ - NCT07607587RecruitingPhase 1
Testing a new weight-loss drug for people who couldn't tolerate GLP-1 shots
This study tests a new injectable medication called cagrilintide for people with obesity who had to stop GLP-1 drugs (like Ozempic or Wegovy) because of stomach problems. The goal is to see if cagrilintide causes fewer stomach side effects while still helping with weight.
Bristol, TennesseeAges 18 years+ - NCT07533175RecruitingPhase 3
Testing a new weight-loss medicine for type 2 diabetes
This study tests whether a new medicine called NNC0487-0111 helps people with type 2 diabetes and excess weight lose weight. You'll take the medicine along with your current diabetes care to see if it works better than standard treatment.
Chattanooga, TennesseeAges 18 years+ - NCT07253285RecruitingPhase 3
Study on cagrilintide and CagriSema for kids with excess weight
This trial tests two new medicines (cagrilintide and CagriSema) to see if they help children and teens lose weight. It's for young people who have tried lifestyle changes without enough success.
Memphis, TennesseeAges 8–18 - NCT06901245RecruitingPhase 4
Tirzepatide for young adults with obesity
This study tests the diabetes/weight-loss drug tirzepatide (Mounjaro) in young adults aged 18–26 who have obesity and either Prader-Willi syndrome, hypothalamic obesity, or general obesity. It looks at whether a weekly injection can help with weight management.
Nashville, TennesseeAges 18–26 - NCT06845046Recruiting
Improving muscle health for veterans with HIV
This study tests a way to help veterans with HIV build stronger muscles. It may help improve your strength and overall health.
Nashville, TennesseeAges 20–80 - NCT06455995Recruiting
Daily eating patterns for total health
This study looks at how different daily eating patterns affect your health. If you are overweight or have obesity, you may be able to join and help researchers find better ways to improve well-being.
Knoxville, TennesseeAges 25–60 - NCT05000996Recruiting
Gut microbiome study for people having metabolic surgery
This study looks at your gut bacteria (your “microbiome”) around the time of metabolic surgery. It may help researchers understand how surgery affects gut health and related conditions like diabetes, blood pressure, and cholesterol.
Nashville, TennesseeAges 21–65 - NCT05972564RecruitingPhase 1/Phase 2
SGLT2 inhibitor for metabolic syndrome and heart health
This study tests whether a diabetes medication called an SGLT2 inhibitor can reduce inflammation in body fat and improve blood vessel function in people with metabolic syndrome. It may help prevent heart disease and other complications.
Nashville, TennesseeAges 18 years+ - NCT03407833Enrolling by invitation
Study changes in the body after weight, gut, or liver treatment
This study looks at how the body’s insulin-sensitivity (how well your body uses sugar/insulin) and organ function change after certain medical procedures. It may help researchers understand why some people improve after surgery or liver transplant and guide future care.
Nashville, TennesseeAges 18 years+ - NCT02646475RecruitingPhase 1
Study angiotensin medicine to improve metabolism in obesity
This Phase 1 study tests how a medication that affects the body’s angiotensin system (angiotensin-(1-7)) changes metabolism in adults with obesity, insulin resistance, and high blood pressure. It may help researchers understand whether this approach can improve blood sugar/insulin function and related body changes.
Nashville, TennesseeAges 18–60
Obesity trials by city in Tennessee
Where these studies are running in Tennessee
Institutions with a site for the recruiting obesity studies listed above.
- Vanderbilt University Medical Center · 8 studies
- Healthy Eating and Activity Laboratory · 2 studies
- Vanderbilt Health One Hundred Oaks · 2 studies
- Accellacare US Inc., d/b/a Accellacare of Knoxville
- AMR Clinical
- Cherokee Health Systems, Dameron Avenue Pedatrics
- DelRicht Research - Thompson's Station
- Holston Medical Group_Bristol
What taking part in a obesity study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Obesity trials in other states
Common questions
- Are there obesity clinical trials in Tennessee?
- Yes. We're currently tracking 48 recruiting obesity studies with a site in Tennessee, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a obesity study in Tennessee?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in Tennessee to take part?
- Not necessarily. These studies have a site in Tennessee, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a obesity trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New obesity studies open in Tennessee regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.