Clinical trials
Obstructive Sleep Apnea clinical trials
Below are recruiting obstructive sleep apnea clinical trials, each written for real people, not researchers. We’re tracking 299 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04991389RecruitingPhase 4
Test a breathing study plan for kids with sleep apnea after surgery
This trial studies how to improve outcomes for children who still have obstructive sleep apnea after having their tonsils and adenoids removed. It uses computer modeling (based on breathing/airflow) and may include a special breathing gas during testing in some parts of the study.
Cincinnati, OhioAges 3–18 - NCT04905238Enrolling by invitation
Sleep apnea study linking breathing markers to memory changes
This trial looks at how severe sleep apnea breathing patterns relate to body “biomarkers” linked to Alzheimer’s disease, using blood or other measures. It may help researchers understand whether sleep apnea is connected to memory and brain health—and who might benefit most from better sleep care.
Palma, Balearic IslandsAges 18–65 - NCT03109171Recruiting
Test accuracy using a scope-based feeling test for sleep apnea
This study checks how accurately a special camera/scope test can measure throat sensation in people being evaluated for obstructive sleep apnea (OSA). If the test works well, it may help improve how clinicians understand and assess OSA-related changes.
Bogotá, Bogota D.C.Ages 18 years+ - NCT04814420Recruiting
Study heart scarring in sleep apnea, with or without atrial fibrillation
This pilot study looks at whether obstructive sleep apnea leads to heart scarring (called atrial fibrosis), especially in people with and without an irregular heart rhythm (atrial fibrillation). It may help researchers understand who is at higher risk and why, using sleep testing and heart imaging.
New Orleans, LouisianaAges 18–75 - NCT04603196Recruiting
Study sleep apnea in adults with multiple sclerosis
This study looks at how often sleep apnea happens in people who have multiple sclerosis, and how it affects daily life and health. You may be invited to participate if you’re an adult with a confirmed multiple sclerosis diagnosis and can consent to the study.
Boston, MassachusettsAges 18 years+ - NCT04335994Recruiting
Home sleep testing for people with memory trouble
This study looks at how well home sleep apnea testing works for people with cognitive impairment (memory/thinking problems) to help improve outcomes. You may be asked to do a home sleep test (and possibly an in-lab test) and will involve a caregiver if needed.
Toronto, OntarioAges Any age - NCT04179981Recruiting
CPAP treatment effects in older COPD and sleep apnea patients
This study looks at whether using positive airway pressure (often called CPAP) improves health outcomes in older adults who have both COPD and obstructive sleep apnea. It may help find ways to reduce symptoms and complications from “overlap” breathing problems.
Detroit, MichiganAges 60 years+ - NCT04124848Recruiting
Sleep apnea study for Somali community adults
This study looks at obstructive sleep apnea—breathing pauses or poor breathing during sleep—in Somali community members. It aims to learn more about sleep apnea in this specific group, which can help guide better care.
Rochester, MinnesotaAges 18 years+ - NCT04112927Recruiting
Sound-based test for sleep apnea
This study uses sound recordings to detect sleep apnea while you are awake and during sleep, which could offer a simpler alternative to traditional sleep studies. If you are suspected of having sleep apnea, this trial may help improve diagnosis and monitoring.
Winnipeg, ManitobaAges 18–70 - NCT04092660Recruiting
Mouth guard study to reduce airway collapse in sleep apnea
This study tests whether using an anti-snoring mouth guard (a mandibular advancement appliance) can help keep your airway open during sleep if you have obstructive sleep apnea. If you’re referred for this kind of mouth guard, the trial will see if using it more regularly or in a specific way improves symptoms or breathing during sleep.
LondonAges 40–90 - NCT02431507Recruiting
First test of an implant device to prevent sleep apnea pauses
This trial is testing whether a new implanted device is safe and feasible for people with moderate to severe obstructive sleep apnea. It may help if you cannot tolerate CPAP (a common breathing device) and your apnea is caused by airflow blockage at the back of the tongue area.
San Francisco, CaliforniaAges 21–70 - NCT03860233RecruitingPhase 1
Oxytocin added to CPAP for obstructive sleep apnea
This early study tests whether adding oxytocin to your usual CPAP treatment improves obstructive sleep apnea. It may help see if oxytocin changes how well CPAP works or how people feel while using it.
Washington D.C., District of ColumbiaAges 18 years+ - NCT03307330Recruiting
Study of body fat in people with obstructive sleep apnea
This study looks at how body fat (“adipose tissue”) may differ in people with obstructive sleep apnea. You may be asked for consent and could be asked to stop certain medicines short-term so researchers can take a safe fat sample.
Rochester, MinnesotaAges 18–60 - NCT03062748Enrolling by invitation
Study tests how sleep apnea and inflammation relate to risk
This study looks at people with mild to moderate obstructive sleep apnea (OSA) to understand how inflammation and breathing disruption may affect future heart and metabolism risk. It may help explain why some people develop higher risk even with milder sleep apnea.
Hershey, PennsylvaniaAges 18 years+ - NCT03255408RecruitingPhase 1/Phase 2
Sleep study testing breathing and blood flow in healthy adults
This study looks at how your brain blood flow and breathing change during sleep under normal oxygen and reduced oxygen. It will only include healthy adults so researchers can learn what “intermittent hypoxia” does to the body in people without medical problems.
Calgary, AlbertaAges 18–45 - NCT02703207Recruiting
Sleep apnea and COPD effects in older veterans
This study looks at how sleep apnea affects thinking skills and overall health in older veterans who also have COPD. It may help researchers understand what changes to target to improve daytime functioning and wellbeing.
Detroit, MichiganAges 60–89 - NCT00695214RecruitingPhase 2
Test with medicine-assisted sleep endoscopy for sleep apnea
This trial studies how well a procedure done while you sleep helps doctors understand the blockage causing obstructive sleep apnea and plan surgery. You may be helped if you’re an adult with sleep apnea who is considering surgical treatment.
Santa Monica, CaliforniaAges 18 years+ - NCT05978505RecruitingPhase 2
Reboxetine for sleep apnea after ENT surgery
This study tests if the medication reboxetine helps reduce sleep apnea symptoms after planned upper airway surgery. It may be a good fit if you have sleep apnea and are having surgery on your nose or throat.
Bedford Park, South AustraliaAges 18 years+ - NCT07332780Recruiting
Tonsil and adenoid surgery for kids with mild breathing troubles during sleep
This study looks at whether removing tonsils and adenoids can help improve spine curves in children who have mild sleep-disordered breathing. It may help prevent scoliosis from getting worse.
Wenzhou, ZhejiangAges 6–15 - NCT07259200Recruiting
Sleep quality after atrial fibrillation ablation
This study looks at how treating AFib with a procedure called catheter ablation might affect your sleep quality. You can join if you have AFib and are already planning to have this procedure, and you also have at least one risk factor for sleep apnea.
Grodzisk MazowieckiAges 18 years+ - NCT06808464Recruiting
Heart rate changes during sleep in severe sleep apnea
This study looks at how your heart rate changes during sleep in people with severe sleep apnea compared to healthy people. It uses a simple overnight recording to measure your nervous system activity.
LilleAges 18–64 - NCT06564896Recruiting
Comparing sleep apnea treatments (CPAP vs alternatives)
This trial compares different positive airway pressure (PAP) machines to see which works best for people with moderate to severe sleep apnea. If you have been diagnosed but haven't used a CPAP yet, this study may help find the best option for you.
Cheras, Kuala LumpurAges 18 years+ - NCT07447284Recruiting
Improving sleep for African American couples with OSA
This study tests whether a couple-based approach helps African American patients with moderate to severe sleep apnea stick with CPAP therapy better. It is designed for patients and their bed partners who want to improve sleep health together.
Cleveland, OhioAges 30 years+ - NCT07220525Recruiting
Sleep and heart rhythm study for people with sleep apnea device
This study looks at how turning off your sleep apnea device for short periods affects your heart rhythm, especially if you have a condition like atrial fibrillation. It may help understand the link between sleep and heart health.
San Francisco, CaliforniaAges 21 years+
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Common questions
- Are there clinical trials for obstructive sleep apnea?
- Yes. Clin2 currently lists 299 recruiting obstructive sleep apnea studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a obstructive sleep apnea trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a obstructive sleep apnea trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.