Clinical trials
Obstructive Sleep Apnea clinical trials
Below are recruiting obstructive sleep apnea clinical trials, each written for real people, not researchers. We’re tracking 299 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06258837Recruiting
Personalized surgery for sleep apnea in children with small tonsils
This study tests a personalized surgical approach for children with moderate to severe obstructive sleep apnea who have small tonsils. The goal is to see if tailored surgery improves their breathing during sleep and overall health.
Ann Arbor, MichiganAges 2–17 - NCT06189755Recruiting
MicroRNA markers for sleep apnea
This trial is studying tiny molecules in the blood (called microRNAs) to see if they can help diagnose or monitor obstructive sleep apnea. It compares people with moderate to severe sleep apnea who are starting PAP therapy with people who do not have sleep apnea.
Columbus, OhioAges 18–75 - NCT06117579Recruiting
Breathing Muscle Training for Sleep Apnea
This trial tests whether a simple breathing exercise (training the muscles you use to breathe in) can improve sleep apnea symptoms in people who already use CPAP. The goal is to see if adding this training helps you feel better or need less CPAP pressure.
OrléansAges 18 years+ - NCT06043440RecruitingPhase 2
Oxygen therapy for sleep apnea in Down syndrome
This study tests whether oxygen therapy can help children with Down syndrome who have sleep apnea. It compares oxygen treatment to no treatment to see if it improves breathing during sleep and thinking skills.
Los Angeles, CaliforniaAges 5–18 - NCT05953610RecruitingPhase 2
Surgery study for sleep apnea when CPAP won’t work
This Phase 2 trial tests whether a specific type of palate surgery can treat moderate-to-severe obstructive sleep apnea in people who cannot tolerate CPAP (a breathing mask). It also checks patient traits (based on sleep testing) to see who is most likely to benefit from surgery.
Santa Monica, CaliforniaAges 21 years+ - NCT05939934Recruiting
Test a mouth device for sleep apnea after stopping CPAP
This study looks at whether a mandibular advancement device (a fitted mouthpiece) can control sleep apnea when you temporarily stop CPAP. It’s mainly for people who have been using CPAP for over a year but are now willing to try the mouth device.
AngersAges 18–75 - NCT05911646Recruiting
Tool to help decisions for mild sleep apnea in kids
This trial looks at OSA-18, a questionnaire that may help families and clinicians make better decisions about treatment for a child’s mild sleep apnea. It specifically focuses on children with enlarged tonsils and mild sleep study results.
Hartford, ConnecticutAges 3–12 - NCT05804084RecruitingPhase 2
Acetazolamide for sleep apnea: sleep and brain outcomes
This study tests acetazolamide (a medicine that changes breathing chemistry) to see how it affects sleep quality and neurocognitive (brain/memory/attention) outcomes in adults with untreated moderate to severe sleep apnea. You may be eligible if you have significant sleep apnea but do not have certain safety risks or need to start standard sleep apnea treatment right away.
La Jolla, CaliforniaAges 18 years+ - NCT04943562Recruiting
Testing sleep sensors to score your sleep stages
This study checks whether wearable sensors (like a sleep band and a wearable EEG) and a phone can accurately identify your sleep stages. It includes healthy people and people with sleep problems to see how well the devices work and whether results match a standard sleep lab test.
São Caetano do Sul, São PauloAges 20–80 - NCT05147649Recruiting
Brain scan study in severe sleep apnea without CPAP
This trial uses a specialized brain scan (MRI) to study people with severe obstructive sleep apnea who are not using CPAP. It also compares them with people who do not have sleep apnea to understand how brain function differs.
ReimsAges 18–75 - NCT05558501RecruitingPhase 1/Phase 2
Intermittent low-oxygen therapy for sleep apnea and health risks
This early-stage study tests a treatment that briefly reduces oxygen during sleep to improve “plasticity,” with the goal of helping people with obstructive or mixed sleep apnea. It also looks at related conditions like high blood pressure and pre-diabetes or cholesterol problems, especially in people who haven’t tried CPAP yet.
Detroit, MichiganAges 30–60 - NCT05656365Recruiting
Study of genes and immunity in PFAPA and other tonsil problems
This study looks at genetic markers and immune system patterns in people with PFAPA (periodic fevers with mouth sores and throat/neck gland symptoms) or similar tonsil problems. It may help researchers understand why these conditions happen and how they might be better diagnosed or treated.
Washington D.C., District of ColumbiaAges 1 month–99 years - NCT05575401Recruiting
Track surgery results in kids getting tonsil removal
This trial looks at how well a specific throat surgery technique works in children who are having their tonsils removed (with or without removing adenoids). It may help improve how doctors choose and perform surgery for safer, better recovery.
Murrieta, CaliforniaAges 3–17 - NCT05539716Recruiting
Treating sleep apnea to study effects on metabolism
This study tests a sleep apnea treatment approach and looks at how it may affect your body’s metabolism. You may be eligible if you’re an adult with sleep apnea and meet health and medication rules, and possibly if you already use a PAP machine regularly.
Miami, FloridaAges 18–70 - NCT05508971Recruiting
Personalized tonsil surgery for sleep apnea in children with Down syndrome
This study tests whether a personalized surgical approach can treat moderate to severe obstructive sleep apnea (OSA) in children with Down syndrome. The goal is to improve breathing during sleep and overall sleep health.
Aurora, ColoradoAges 2–17 - NCT05527652Recruiting
Breathing tube device to help blocked upper airways in children
This study tests a self-supporting breathing tube placed through the nose during sleep to reduce upper airway blockage and improve breathing in children. It may help children who have sleep apnea symptoms, especially after tonsil/adenoid treatment or when tonsil removal isn’t possible.
Ann Arbor, MichiganAges 3–21 - NCT05497180RecruitingPhase 1
Testing an oral device to reduce snoring and mild sleep apnea
This Phase 1 study tests whether a passive mouth/oral appliance can lessen snoring and mild obstructive sleep apnea. It may help you by improving airflow during sleep without other intensive treatments.
Edmonton, AlbertaAges 18 years+ - NCT05459935Recruiting
Light treatment for enlarged tonsils in children
This trial studies whether a light-based treatment (called photobiomodulation) can help children with very enlarged tonsils. It may improve breathing and sleep symptoms, and you’d have before-and-after checkups, including sleep testing.
Edmonton, AlbertaAges 6–12 - NCT05382754Recruiting
Home sleep testing for children being checked for sleep apnea
This trial tests whether home sleep testing can help diagnose sleep apnea in children. It is for kids who are already being referred for an in-lab sleep study at CHOP.
Philadelphia, PennsylvaniaAges 5–12 - NCT05350332Recruiting
Testing how lung air volume affects airway narrowing during sleep testing
This study looks at whether changing lung air volume affects how open or blocked your upper airway is during a drug-induced sleep test (DISE). It may help guide surgical choices for people with obstructive sleep apnea (OSA).
Atlanta, GeorgiaAges 18 years+ - NCT05289063RecruitingPhase 1
Study new sleep apnea and blood vessel function
This Phase 1 study looks at how blood vessel function is affected by obstructive sleep apnea in adults who are newly diagnosed and have not used CPAP. It may help researchers understand the early effects of sleep apnea and guide future treatments.
New York, New YorkAges 18 years+ - NCT05303987RecruitingPhase 2
Dexmedetomidine or propofol for sleep endoscopy in children
This Phase 2 study compares two medicines used to help children sleep during a procedure called drug-induced sleep endoscopy. It’s for children with obstructive sleep apnea who are being evaluated before adenotonsillectomy, to help surgeons understand the cause of the blockage and potentially improve treatment planning.
Ann Arbor, MichiganAges 3–11 - NCT05237505RecruitingPhase 2
Sleep apnea plus COPD study to check heart and breathing effects
This Phase 2 study looks at the cardiovascular (heart/blood vessel) effects of having both sleep apnea and COPD. It may help doctors better understand who is at risk and how to manage these breathing problems together.
La Jolla, CaliforniaAges 40–79 - NCT05052216Recruiting
Wearable monitor study for kids’ sleep apnea
This study tests a wearable device that can help monitor breathing and sleep in children. It compares children with sleep apnea to children without sleep apnea using a simple nighttime monitoring approach.
Bethesda, MarylandAges 3–12
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Common questions
- Are there clinical trials for obstructive sleep apnea?
- Yes. Clin2 currently lists 299 recruiting obstructive sleep apnea studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a obstructive sleep apnea trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a obstructive sleep apnea trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.