Clinical trials
Open Label clinical trials
Below are recruiting open label clinical trials, each written for real people, not researchers. We’re tracking 367 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06663137RecruitingPhase 2
Study of a new treatment for high-grade bladder cancer
This trial tests a new treatment called NDV01 KIT for people with high-grade non-muscle invasive bladder cancer that hasn't gotten better after BCG therapy. It's for those who cannot or choose not to have their bladder removed.
RaananaAges 18–80 - NCT06668181RecruitingPhase 3
Study of bimekizumab for kids with certain types of juvenile arthritis
This trial tests a drug called bimekizumab in children and teens with specific types of juvenile arthritis (enthesitis-related arthritis or psoriatic arthritis). It aims to see how the drug works in the body and if it's safe. This may help those who haven't gotten enough relief from standard anti-inflammatory medicines.
CalgaryAges 2–18 - NCT06668142Recruiting
Beacon platform study for prostate surgery
This trial tests a new surgical platform called Beacon during HoLEP, a common procedure to treat enlarged prostate symptoms. It may help men with difficulty urinating due to an enlarged prostate.
Santiago, Santiago MetropolitanAges 45 years+ - NCT06668792RecruitingPhase 2
Study of BCD-248 for returning multiple myeloma
This trial tests a new treatment called BCD-248 for people whose multiple myeloma has come back or stopped responding to at least two prior treatments. It aims to see if it is safe and effective.
KaliningradAges 18 years+ - NCT06671093RecruitingPhase 1
Study of Tune-401 for chronic hepatitis B
This study tests a new medicine, Tune-401, for adults with chronic hepatitis B who are already on a daily antiviral pill. The goal is to see if it is safe and can reduce the virus in your body.
Hong KongAges 18–75 - NCT06676007Recruiting
Early use of a targeted budesonide for IgA nephropathy
This trial tests starting a special form of budesonide (Nefecon) early in people with IgA nephropathy, a kidney disease. The goal is to see if it can reduce protein in the urine and protect kidney function.
Chengdu, SichuanAges 18–75 - NCT06679881RecruitingPhase 3
Preventing swelling attacks with oral deucrictibant for HAE
This study tests a long-term daily pill to prevent swelling attacks in people with hereditary angioedema (HAE). The pill, called deucrictibant, is designed to block a protein involved in causing attacks. It's for adolescents and adults who want to reduce how often swelling episodes occur.
Birmingham, AlabamaAges 12 years+ - NCT06680830RecruitingPhase 2
Testing NEU-411 for early Parkinson's with LRRK2 gene change
This trial tests an experimental drug called NEU-411 for people with early Parkinson's disease who have a specific genetic change (LRRK2). It aims to see if the drug can slow the disease progression.
Sun City, ArizonaAges 40–80 - NCT06692179RecruitingPhase 1
Testing a freeze-dried fecal transplant during colon surgery
This trial tests if giving a special freeze-dried mixture of healthy gut bacteria right after colon surgery is safe and possible. It may help patients recover better after the procedure.
Minneapolis, MinnesotaAges 18–75 - NCT06700096RecruitingPhase 3
Testing a new drug for adults with severe hemophilia B
This trial tests a single dose of ANB-002, an experimental therapy for hemophilia B. It aims to see if the drug is safe and effective for people with severe hemophilia B who have been treated with factor IX before and do not have inhibitors.
ChelyabinskAges 18 years+ - NCT06705296RecruitingPhase 1
Deep brain stimulation for severe PTSD
This trial tests whether deep brain stimulation, a surgery that uses a small device to send electrical pulses to specific brain areas, can help people with severe PTSD that hasn't improved after trying several treatments. It aims to see if this approach is safe and effective for long-lasting symptoms.
Toronto, OntarioAges 18–70 - NCT03530852Recruiting
RELIZORB test for children needing tube feeding and IV nutrition
This study tests whether RELIZORB helps children with short bowel syndrome (SBS), who rely on IV nutrition (and also tube feeding), absorb fats better. It is an open-label study over 90 days, meaning everyone gets the study treatment and outcomes are compared over time.
Los Angeles, CaliforniaAges 2–18 - NCT07682948RecruitingPhase 1
Drug interaction study of UIC202601 and UIC202602 in healthy volunteers
This trial tests how two experimental drugs, UIC202601 and UIC202602, interact with each other in the body. Healthy volunteers take both drugs to check for side effects and how the body processes them.
Anyang, Manan-guAges 19–54 - NCT07171489Recruiting
Wearable device for bowel control after spinal cord injury
This trial tests a wearable device that uses mild electrical pulses to help manage bowel function in people with spinal cord injury. It aims to improve control and quality of life.
Ann Arbor, MichiganAges 18 years+ - NCT06435312Enrolling by invitationPhase 3
Studying zilucoplan for children with generalized myasthenia gravis
This study gives an injectable medicine called zilucoplan to children who were part of an earlier trial and could benefit from more treatment. It aims to see if zilucoplan is safe and helpful for young patients with generalized myasthenia gravis.
MilanAges 12 years+ - NCT05635747Enrolling by invitation
90-day follow-up study for children using RELiZORB
This study follows children who are already taking RELiZORB to see how it’s going over time and whether it remains safe and tolerable, with effects on nutrient absorption. It doesn’t change treatment—it mainly looks at outcomes during the next 90 days.
Los Angeles, CaliforniaAges 2–18 - NCT06720558Recruiting
Placebo probiotic effects on gut health in mild GI symptoms
This study tests whether a placebo probiotic can improve gut health and overall well-being in people with mild digestive issues like gas, bloating, or irregularity. If you have mild symptoms that don't stop your daily activities, this trial may help understand if believing you're taking a probiotic can make you feel better.
MilanAges 20–65 - NCT06724653Recruiting
Reducing Heart Failure Meds After Heart Recovery Study
This trial tests whether it is safe to slowly reduce some heart failure medications for people whose heart function has improved to normal. It is for patients who once had a weak heart pump but now have recovered strength and are stable on multiple medicines.
Jeonju, Jeollabuk-doAges 18 years+ - NCT06728852RecruitingPhase 2
Vorolanib for advanced lung cancer after other treatments
This trial tests a targeted therapy pill called Vorolanib for people with advanced non-small cell lung cancer who have already tried at least two other treatments. It aims to see if the drug can help shrink or control the cancer.
Guangzhou, GuangdongAges 18–70 - NCT06728865RecruitingPhase 2
Furmonertinib plus Avastin for EGFR+ lung cancer with brain mets
This trial tests a combination of two targeted drugs (Furmonertinib and Avastin) as the very first treatment for people with a specific type of lung cancer (EGFR-mutant non-small cell) that has spread to the brain. The goal is to see how well it works and how safe it is.
Guangzhou, GuangdongAges 15–75 - NCT06758544RecruitingPhase 1/Phase 2
VRT106 plus chemo for resectable pancreatic cancer
This trial tests a new drug called VRT106 combined with chemotherapy for people with pancreatic cancer that can be surgically removed. The goal is to see if the combination works better than standard treatment alone.
Guangzhou, GuangdongAges 18–75 - NCT06772220Recruiting
Homocysteine management for Parkinson's patients on levodopa
This trial tests whether controlling homocysteine levels can help people with Parkinson's disease who are taking levodopa. You may qualify if you take at least 300 mg of levodopa per day, are between 40 and 90 years old, and have no major kidney problems or uncontrolled high blood pressure.
Portland, OregonAges 40–90 - NCT06780670RecruitingPhase 2/Phase 3
Comparing a new drug to standard care for prostate cancer
This trial tests a new study drug (AAA817) against the usual treatments for men with a certain type of advanced prostate cancer that has spread and is no longer responding to a targeted radiation therapy (177Lu-PSMA). The goal is to see if the new drug can help control the disease longer.
Los Angeles, CaliforniaAges 18–100 - NCT06785844RecruitingEarly Phase 1
Botulinum toxin injection for children with hard-to-treat bowel leakage
This trial tests a one-time injection of botulinum toxin (like Botox) into the bottom muscle to help children who have frequent, stubborn bowel leakage. It aims to see if relaxing the muscle can reduce accidents.
JerusalemAges 4–18
Hear when a new Open Label trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for open label?
- Yes. Clin2 currently lists 367 recruiting open label studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a open label trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a open label trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.