Clinical trials
Open Label clinical trials
Below are recruiting open label clinical trials, each written for real people, not researchers. We’re tracking 366 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06896305Recruiting
Adding a Special Diet to Anti-TNF Therapy for Crohn's and Colitis
This study tests whether adding a special diet (the Crohn's Disease Exclusion Diet) to standard anti-TNF medicine works better than the medicine alone for people with moderate to severe Crohn's disease or ulcerative colitis. You would be asked to follow a specific meal plan for several weeks while taking your regular medication.
Milan, MichiganAges 18 years+ - NCT06871488RecruitingPhase 4
ADHD irritability & aggression treatment with stimulants
This study tests whether CNS stimulant medications can improve irritability and aggression in children with ADHD. It looks for factors that predict who will benefit most.
Hershey, PennsylvaniaAges 7–12 - NCT06858319RecruitingPhase 3
Long-term study of zigakibart for IgA nephropathy
This study is for people with IgA nephropathy who completed a previous zigakibart study. It tests whether continuing treatment with zigakibart (given as a shot every two weeks) is safe and helpful over a longer period.
Denver, ColoradoAges 18–100 - NCT06867107Enrolling by invitationPhase 2
Long-term follow-up study of SAT-3247 for Duchenne muscular dystrophy
This study follows people with Duchenne muscular dystrophy who were in an earlier SAT-3247 trial, or who meet certain other criteria, to see how the medicine works over a longer time. It aims to gather more safety and effectiveness information.
Los Angeles, CaliforniaAges 16–40 - NCT06484868RecruitingPhase 4
Study of metreleptin for partial lipodystrophy
This trial tests an open-label study of metreleptin in people with partial lipodystrophy, a condition where fat is lost from some areas of the body. The goal is to see if the drug can help manage related health problems.
LilleAges 12 years+ - NCT06836232RecruitingPhase 2
Study of VTX2735 for recurring pericarditis
This trial tests an experimental drug called VTX2735 for people with recurring pericarditis (inflammation around the heart). It aims to see if the drug can help reduce pain and inflammation during a flare-up.
La Jolla, CaliforniaAges 18–75 - NCT05862064RecruitingPhase 3
Adding an immune drug and anti-blood-vessel treatment to chemo
This study tests whether adding an immune therapy (a PD-1 antibody) plus a blood-vessel–blocking treatment to standard chemo improves outcomes for people with surgically treated triple-negative breast cancer. Everyone gets chemotherapy, but some will also get the added drugs to try to reduce cancer coming back.
Shanghai, Shanghai MunicipalityAges 18–70 - NCT06813339RecruitingEarly Phase 1
Testing a new drug in healthy people and those with heart condition
This trial tests a new medicine called UDP-003 in two groups: healthy volunteers and people who had a heart event (acute coronary syndrome) at least a year ago. The goal is to see if the drug is safe and how the body handles it, which could lead to better treatments for heart disease.
Adelaide, South AustraliaAges 18–79 - NCT06793917RecruitingPhase 3
Immunotherapy plus chemo vs. chemo alone for advanced stomach cancer
This trial compares two types of chemotherapy with or without an immunotherapy drug (tislelizumab) for advanced stomach or gastroesophageal junction cancer. It aims to see which combination works better and has fewer side effects.
Fuzhou, FujianAges 18–70 - NCT06785844RecruitingEarly Phase 1
Botulinum toxin injection for children with hard-to-treat bowel leakage
This trial tests a one-time injection of botulinum toxin (like Botox) into the bottom muscle to help children who have frequent, stubborn bowel leakage. It aims to see if relaxing the muscle can reduce accidents.
JerusalemAges 4–18 - NCT06780670RecruitingPhase 2/Phase 3
Comparing a new treatment to standard care for advanced prostate cancer
This study tests a new drug (AAA817) against the usual treatments for men with advanced prostate cancer that has stopped responding to a type of targeted radiation therapy (Lu-PSMA). The goal is to see if the new drug can slow the cancer's growth better than standard options.
Scottsdale, ArizonaAges 18–100 - NCT05929495RecruitingPhase 2
Metformin added to standard treatment for newly diagnosed glioblastoma
This Phase 2 study tests whether adding metformin to the usual treatment for newly diagnosed glioblastoma (GBM) can improve outcomes. It involves taking metformin after surgery along with standard care (the Stupp protocol).
MilanAges 18 years+ - NCT06762431RecruitingPhase 1/Phase 2
CAR T-cell therapy plus lenalidomide for CLL
This trial tests a combination of two treatments—CAR T-cells (your own immune cells reprogrammed to attack cancer) and lenalidomide (a pill that boosts the immune system)—for people with chronic lymphocytic leukemia (CLL) that has not responded to or returned after at least one prior treatment. It aims to see if this combination is safe and works better than either alone.
Vitebsk, Select A StateAges 18 years+ - NCT06758544RecruitingPhase 1/Phase 2
VRT106 plus chemo for resectable pancreatic cancer
This trial tests a new drug called VRT106 combined with chemotherapy for people with pancreatic cancer that can be surgically removed. The goal is to see if the combination works better than standard treatment alone.
Guangzhou, GuangdongAges 18–75 - NCT05994690RecruitingPhase 3
Newly diagnosed pediatric AML trial with extra treatment options
This trial studies different treatment plans for children and teens newly diagnosed with AML (a type of blood cancer). Depending on the child's tumor markers and risk group, they may be offered an extra drug (quizartinib) or a targeted antibody (Mylotarg) to see if it improves outcomes.
Utrecht, UtrechtAges 1 day–18 years - NCT06724653Recruiting
Reducing Heart Failure Meds After Heart Recovery Study
This trial tests whether it is safe to slowly reduce some heart failure medications for people whose heart function has improved to normal. It is for patients who once had a weak heart pump but now have recovered strength and are stable on multiple medicines.
Jeonju, Jeollabuk-doAges 18 years+ - NCT06710288RecruitingPhase 2
Immune cell therapy plus chemo for platinum-resistant ovarian cancer
This trial tests a new combination therapy for advanced ovarian cancer that has stopped responding to platinum-based chemo. You will receive your own immune cells (M-CENK) boosted with an immune stimulator (N-803) plus chemotherapy (gemcitabine) to see if this helps fight the cancer.
El Segundo, CaliforniaAges 18–85 - NCT06714864RecruitingPhase 4
Preventing catheter infections in children on dialysis
This study tests a liquid that is put into the dialysis catheter after each session to prevent infections that can happen through the catheter. It is designed for children up to age 18 who need hemodialysis through a catheter.
Birmingham, AlabamaAges Up to 17 years - NCT06716073Recruiting
Endoscopic vs standard breast-conserving surgery after chemo
This study compares two types of breast-conserving surgery for women who have already had chemotherapy before their operation. It aims to see if using a tiny camera (endoscope) leads to equally good long-term results as standard breast-conserving surgery.
Guangzhou, GuangdongAges 18–75 - NCT06700096RecruitingPhase 3
Testing a new drug for adults with severe hemophilia B
This trial tests a single dose of ANB-002, an experimental therapy for hemophilia B. It aims to see if the drug is safe and effective for people with severe hemophilia B who have been treated with factor IX before and do not have inhibitors.
ChelyabinskAges 18 years+ - NCT06680830RecruitingPhase 2
Testing NEU-411 for early Parkinson's with LRRK2 gene change
This trial tests an experimental drug called NEU-411 for people with early Parkinson's disease who have a specific genetic change (LRRK2). It aims to see if the drug can slow the disease progression.
Sun City, ArizonaAges 40–80 - NCT06679270RecruitingPhase 3
Long-term safety study of metreleptin for partial lipodystrophy
This study tests the long-term safety of metreleptin for people with partial lipodystrophy. It is for those who already completed a related study and want to continue treatment.
Birmingham, AlabamaAges 13 years+ - NCT06679881Enrolling by invitationPhase 3
Daily oral tablet to prevent hereditary angioedema attacks
This study tests a daily oral tablet called deucrictibant to see if it can prevent swelling attacks in people with hereditary angioedema (HAE). If you join, you will take the study drug for a longer period and track your symptoms in a diary.
Birmingham, AlabamaAges 12 years+ - NCT06671093RecruitingPhase 1
Study of Tune-401 for chronic hepatitis B
This study tests a new medicine, Tune-401, for adults with chronic hepatitis B who are already on a daily antiviral pill. The goal is to see if it is safe and can reduce the virus in your body.
Hong KongAges 18–75
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Common questions
- Are there clinical trials for open label?
- Yes. Clin2 currently lists 366 recruiting open label studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a open label trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a open label trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.