Clinical trials
Overweight or Obese Adults clinical trials
Below are recruiting overweight or obese adults clinical trials, each written for real people, not researchers. We’re tracking 800 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05530538Recruiting
Phone app program to help teens manage weight
This study tests a weight-management app (the BrainWeighve app) for teens. It looks at whether the app is workable and helpful for teens who are motivated to change weight habits.
Los Angeles, CaliforniaAges 14–21 - NCT05503927Enrolling by invitation
Study of Wegovy safety during pregnancy
This study looks at health outcomes for pregnant women and their babies after taking Wegovy or other weight-loss medicines. It may help understand if these medicines are safe during pregnancy.
Ann Arbor, MichiganAges 15–50 - NCT05316493RecruitingPhase 2/Phase 3
Weight-loss and progesterone treatments for early uterine lining disease
This trial studies a weight-management approach plus a progesterone-releasing IUD (LNG-IUS) and megestrol to treat endometrial atypical hyperplasia, a high-risk precancer of the uterine lining. It may help shrink or control the abnormal cells while supporting fertility or keeping the uterus.
ShanghaiAges 18–45 - NCT05234125Recruiting
Lifestyle counseling during pregnancy for African American women
This trial tests a better lifestyle counseling program during pregnancy to help improve health—especially for women who started pregnancy at a higher weight. It may help you learn practical changes for a healthier pregnancy and outcomes.
Chicago, IllinoisAges 18–40 - NCT04791371Recruiting
Study how fitness and insulin resistance relate to diabetes
This study looks at how low physical activity, insulin resistance in small blood vessels, and cardiorespiratory fitness connect to diabetes and blood sugar control. You may be eligible if you are generally sedentary and fit within the weight range, and if you do not have certain heart, lung, nerve, or medication factors.
Aurora, ColoradoAges 30–55 - NCT04824248Recruiting
Weight-loss program for chronic low back pain
This trial studies whether weight loss can improve long-lasting, non-specific low back pain. It may help people whose back pain is partly related to extra weight by testing a structured approach over time.
BrusselsAges 18–65 - NCT04603859Recruiting
When to induce labor for people with higher weight
This study looks at the best timing to start labor (induction) during pregnancy for people with a higher body weight. It may help reduce risks by comparing earlier vs later induction in otherwise eligible pregnancies.
AarhusAges 18 years+ - NCT04496895Recruiting
Orange peel drink study for reducing body fat
This trial looks at whether a fermented orange peel product can lower body fat in adults. It may help if you have higher body fat and/or fatty liver, and you meet safety and health limits.
Taipei, TaiwanAges 20–65 - NCT04583514Recruiting
Overfeeding study to see how body fat can expand
This trial studies how your body’s fat tissue changes when you eat extra food for 8 weeks. It may help researchers understand why some people gain more weight than others.
Baton Rouge, LouisianaAges 18–42 - NCT04453072Recruiting
iPhone weight-loss app for teens and young adults after transplant
This study tests whether an iPhone weight-management app can help adolescents and young adults lose weight after a stem cell transplant. If you qualify, you’ll use the app and the team will track changes in weight.
Los Angeles, CaliforniaAges 13–30 - NCT04297592Enrolling by invitationPhase 4
Antibiotics to prevent infection after hip or knee replacement
This trial studies whether giving antibiotics before and/or after surgery can lower the chance of a serious joint infection after elective hip or knee replacement. It’s aimed at people at higher risk for infection.
Iowa City, IowaAges 18–99 - NCT03927638Enrolling by invitation
Standing versus sitting study for heart and metabolism measures
This trial compares how different body positions (sitting vs standing) affect blood and heart-related measurements in otherwise healthy adults. It may help researchers understand which position is better for metabolic and cardiovascular health.
Montclair, New JerseyAges 18–50 - NCT03851458Enrolling by invitationPhase 2
Spanish coaching for healthier food choices for weight
This Phase 2 study tests a program (with food guidance, text messages, and check-ins) to help people eat more healthfully. It is designed for adults who are overweight or obese and can speak Spanish (with some separate tracks for different groups).
New York, New YorkAges 18 years+ - NCT07763574Enrolling by invitation
Strength training and omega-3 for muscle and brain health
This study tests whether combining strength training with omega-3 supplements improves muscle strength and thinking skills in healthy adults. You would either join an exercise group or a non-exercising control group.
GdanskAges 25–35 - NCT05606731Recruiting
Family coaching to help prevent childhood weight gain
This study offers a family-focused program for Latino adult caregivers of young children to help prevent childhood obesity. If your child is already overweight, the program may help you learn practical ways to support healthier habits as a family.
Los Angeles, CaliforniaAges 2 years+ - NCT07219589RecruitingPhase 1
Study of HM17321 in healthy and obese participants
This trial tests a new medicine, HM17321, to see how the body processes it. It is for healthy adults and adults with obesity who want to help find new treatment options.
Cincinnati, OhioAges 18–65 - NCT07028814Enrolling by invitation
Risk-Informed Weight Care Plan for Children
This trial tests a personalized care plan for children with overweight or obesity. If your child qualifies, you'll work with their doctor on a plan to help manage their weight.
Boston, MassachusettsAges 2–12 - NCT06320158Recruiting
Understanding muscle loss and obesity in older adults
This study looks at the link between muscle loss (sarcopenia) and obesity in older adults. It aims to understand why some older people who are overweight or obese also lose muscle strength and function, and how this affects recovery after hip surgery.
MilanAges 65–99 - NCT06791837Recruiting
Brain blood flow and lactate in obesity study
This study looks at how blood flow and lactate (a chemical your body makes) in the brain differ between people with a healthy weight and those with obesity. It may help researchers understand how weight affects brain function.
Columbia, MissouriAges 18–45 - NCT07877090Recruiting
Brain activity during anesthesia in people with obesity
This study looks at how anesthesia affects brain waves in people with obesity compared to people with normal weight. It may help doctors understand if anesthesia needs to be adjusted for people with obesity.
Düzce, DüzceAges 18 years+ - NCT01344525Recruiting
Study of team-based therapy for obesity and weight loss
This study looks at an interdisciplinary, team-based obesity treatment plan and how well it helps people lose significant weight over time. You might be a candidate if you are an adult with obesity who already achieved more than 10% weight loss within about 6 months from a lifestyle program or weight-loss surgery.
HeidelbergAges 18–65 - NCT04604626Recruiting
Study rare obesity linked to eating and brain conditions
This study aims to improve diagnosis and treatment planning for people with severe obesity—especially when it may be related to a genetic cause or a brain condition affecting appetite. You may be invited if your case includes clues from your history or symptoms, and you can consent to genetic testing discussions as part of usual care.
La DefenseAges Any age - NCT05494138Recruiting
AI-based nutrition study for adults with obesity and normal weight
This study uses nutrition information and artificial intelligence to better understand diet patterns in adults with obesity and in adults with normal weight. Your results may help researchers design better nutrition guidance for people with obesity and related health risks.
SeoulAges 19 years+ - NCT04721873RecruitingPhase 2
Weight-loss medicine for people with ulcerative colitis
This study tests whether a weight-loss medication, along with usual ulcerative colitis care, can help people who have both ulcerative colitis and obesity. It focuses on people with active symptoms or who need ongoing steroid medicine, and it also checks safety with heart, blood, infection, and mental-health screenings.
La Jolla, CaliforniaAges 18–80
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Common questions
- Are there clinical trials for overweight or obese adults?
- Yes. Clin2 currently lists 800 recruiting overweight or obese adults studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a overweight or obese adults trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a overweight or obese adults trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.