Clinical trials
Overweight or Obese Adults clinical trials
Below are recruiting overweight or obese adults clinical trials, each written for real people, not researchers. We’re tracking 807 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06923735Enrolling by invitation
Nutrition app pilot for employee health checks
This pilot study tests a nutrition app to help employees manage conditions like high cholesterol, high blood pressure, weight issues, or type 2 diabetes. It is part of your regular occupational health check or dietitian visit.
KuopioAges 18–75 - NCT06845345Enrolling by invitationPhase 4
Can a special diet or pills help liver health?
This study compares two treatments for liver scarring in people with overweight or related health issues. One group follows a special diet with restricted eating times, while the other takes a combination of two medications (naltrexone and bupropion). It aims to see which approach better improves liver fibrosis.
RotterdamAges 18–75 - NCT06509776Enrolling by invitation
Bone growth and hormone health in young adults
This study looks at how bones mature and how hormones change as you become a young adult. If you were born in Denmark in 2006 or 2007 and are 18, you may be invited to help researchers understand these changes.
AalborgAges 18–19 - NCT05872022Enrolling by invitation
Safety study of Wegovy exposure during pregnancy
This study tracks the safety of taking Wegovy during pregnancy. Researchers want to understand potential risks and outcomes when people are exposed to Wegovy in early or any stage of pregnancy.
Princeton, New JerseyAges 15–50 - NCT05826379Enrolling by invitation
Daily goal setting to boost movement and brain health
This trial tests whether a daily goal-setting program and activity tracking can increase everyday physical activity and support thinking/brain health in midlife. You may be asked to wear devices and meet activity-monitoring requirements during the study.
Hershey, PennsylvaniaAges 30–70 - NCT03927638Enrolling by invitation
Standing versus sitting study for heart and metabolism measures
This trial compares how different body positions (sitting vs standing) affect blood and heart-related measurements in otherwise healthy adults. It may help researchers understand which position is better for metabolic and cardiovascular health.
Montclair, New JerseyAges 18–50 - NCT03851458Enrolling by invitationPhase 2
Spanish coaching for healthier food choices for weight
This Phase 2 study tests a program (with food guidance, text messages, and check-ins) to help people eat more healthfully. It is designed for adults who are overweight or obese and can speak Spanish (with some separate tracks for different groups).
New York, New YorkAges 18 years+ - NCT07763574Enrolling by invitation
Strength training and omega-3 for muscle and brain health
This study tests whether combining strength training with omega-3 supplements improves muscle strength and thinking skills in healthy adults. You would either join an exercise group or a non-exercising control group.
GdanskAges 25–35 - NCT06320158Recruiting
Understanding muscle loss and obesity in older adults
This study looks at the link between muscle loss (sarcopenia) and obesity in older adults. It aims to understand why some older people who are overweight or obese also lose muscle strength and function, and how this affects recovery after hip surgery.
MilanAges 65–99 - NCT05606731Recruiting
Family coaching to help prevent childhood weight gain
This study offers a family-focused program for Latino adult caregivers of young children to help prevent childhood obesity. If your child is already overweight, the program may help you learn practical ways to support healthier habits as a family.
Los Angeles, CaliforniaAges 2 years+ - NCT06549062Recruiting
Paracetamol dosing in obese vs non-obese surgery patients
This trial studies how the body processes intravenous paracetamol (Tylenol) in people with and without obesity. It aims to find the right dose for safety and effectiveness during laparoscopic surgery.
Ghent, Oost-VlaanderenAges 18–70 - NCT06791837Recruiting
Brain blood flow and lactate in obesity study
This study looks at how blood flow and lactate (a chemical your body makes) in the brain differ between people with a healthy weight and those with obesity. It may help researchers understand how weight affects brain function.
Columbia, MissouriAges 18–45 - NCT07219589RecruitingPhase 1
Study of HM17321 in healthy and obese participants
This trial tests a new medicine, HM17321, to see how the body processes it. It is for healthy adults and adults with obesity who want to help find new treatment options.
Cincinnati, OhioAges 18–65 - NCT07028814Enrolling by invitation
Risk-Informed Weight Care Plan for Children
This trial tests a personalized care plan for children with overweight or obesity. If your child qualifies, you'll work with their doctor on a plan to help manage their weight.
Boston, MassachusettsAges 2–12 - NCT03288207Recruiting
Phone-based coaching to help overweight Black women improve heart health
This study tests a mobile app (phone-based program) to help overweight or obese African American women improve weight and cardiovascular (heart) health. You’ll also use a wrist activity monitor, and you may be offered optional MRI scans for extra measurements.
Bethesda, MarylandAges 21–75 - NCT05463796Recruiting
Prevention and early detection for people at high cancer risk
This study looks at surveillance (watching closely), prevention, and early “interception” steps to lower the chance that cancer will develop or be found later. It is for people with genetic risk, past cancer treatment exposures, strong family history, or certain early pre-cancer or high-risk conditions.
Boston, MassachusettsAges Any age - NCT05918575Recruiting
Breathing support after a breathing tube in very obese adults
This trial tests whether giving noninvasive breathing support (using a mask or similar device, without a new breathing tube) right after removing a breathing tube works better for severely obese adults. It mainly looks at people at higher risk of needing help breathing again after extubation.
Chicago, IllinoisAges 18 years+ - NCT06899178RecruitingPhase 2
Atomoxetine for genetic obesity due to MC4R changes
This trial tests a medicine called atomoxetine (Strattera) to help people with a specific genetic form of obesity lose weight. It may be an option if you have a change in the MC4R gene and have not used certain other medications recently.
New York, New YorkAges 6 years+ - NCT07638046RecruitingPhase 2
Mindful Walking and Brain Function in Older Adults
This study looks at how mindful walking—combining walking with focused attention—affects thinking and memory in older adults at risk for dementia. Researchers will track your brain activity and daily movement to see if this approach helps protect brain health.
Columbia, South CarolinaAges 60 years+ - NCT07693426RecruitingPhase 1
Study of efsubaglutide alfa for obese teenagers
This trial tests an injection called efsubaglutide alfa to help obese teenagers lose weight. It requires following diet and exercise advice for at least 3 months before starting.
Beijing, Beijing MunicipalityAges 12–17 - NCT07736547Enrolling by invitation
AI-guided supplement for weight loss
This study tests a nutritional supplement (guided by your gut bacteria) to help with weight loss, along with lifestyle advice. It might be a good fit if you are overweight but not diabetic and have not used weight-loss medications recently.
IstanbulAges 18–65 - NCT04087655Recruiting
Study obesity and tiny blood-vessel function in women
This study looks at how obesity affects tiny blood vessels and blood flow. It also checks whether a specific training/exercise approach changes these “microvascular” effects in premenopausal women who fit certain metabolic risk criteria.
Tallahassee, FloridaAges 18–45 - NCT04604626Recruiting
Study rare obesity linked to eating and brain conditions
This study aims to improve diagnosis and treatment planning for people with severe obesity—especially when it may be related to a genetic cause or a brain condition affecting appetite. You may be invited if your case includes clues from your history or symptoms, and you can consent to genetic testing discussions as part of usual care.
La DefenseAges Any age - NCT04613791Recruiting
Alcohol and addictive behaviors in people with obesity
This study looks at how often people with obesity struggle with alcohol or other addictive behaviors, and how these issues change over time. Understanding this connection may help doctors better support patients managing obesity.
NîmesAges 18 years+
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Common questions
- Are there clinical trials for overweight or obese adults?
- Yes. Clin2 currently lists 807 recruiting overweight or obese adults studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a overweight or obese adults trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a overweight or obese adults trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.