Clinical trials
Overweight or Obese Adults clinical trials
Below are recruiting overweight or obese adults clinical trials, each written for real people, not researchers. We’re tracking 800 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05917795Recruiting
Endoscopic stomach reduction for weight loss before kidney transplant
This trial tests an endoscopic procedure that helps reduce stomach size to support weight loss in people with severe kidney disease who may need a kidney transplant. It may help some patients meet transplant-center weight requirements and potentially improve readiness for transplant care.
RomeAges 18–70 - NCT07824453Recruiting
Exercise program for teens with obesity
This study tests a program that uses gentle reminders to help teenagers with obesity exercise more. It aims to see if this approach can help with weight management and improve health.
Nanjing, JiangsuAges 10–19 - NCT07810517Recruiting
Probiotic and fiber supplement for memory in obesity
This study tests a daily supplement (a probiotic called Lactobacillus acidophilus plus a fiber called inulin) to see if it might help improve memory and thinking in adults with long-term obesity and mild cognitive impairment. If you qualify, you would take the supplement or a placebo for a period of time while the study team monitors your cognitive function.
Huixquilucan, State of MexicoAges 30–40 - NCT07804290Enrolling by invitation
Recovery and satisfaction after metabolic surgery
This study looks at how well patients recover and how satisfied they are after metabolic surgery (weight-loss surgery) at a hospital in Gauteng, South Africa. It uses simple questionnaires to understand the patient experience.
Ga-Rankuwa, GautengAges 18 years+ - NCT07736547Enrolling by invitation
AI-guided supplement for weight loss
This study tests a nutritional supplement (guided by your gut bacteria) to help with weight loss, along with lifestyle advice. It might be a good fit if you are overweight but not diabetic and have not used weight-loss medications recently.
IstanbulAges 18–65 - NCT05277532Recruiting
Exercise and sleep timing for overweight type 1 diabetes
This trial studies whether changing daily sleep timing (circadian rhythm) and doing physical exercise can improve health outcomes in people who are overweight and have type 1 diabetes (or in some healthy people). It may help by seeing what combinations of routine and activity are most beneficial.
StockholmAges 18–50 - NCT07693426RecruitingPhase 1
Study of efsubaglutide alfa for obese teenagers
This trial tests an injection called efsubaglutide alfa to help obese teenagers lose weight. It requires following diet and exercise advice for at least 3 months before starting.
Beijing, Beijing MunicipalityAges 12–17 - NCT07693608Enrolling by invitationPhase 2
Tirzepatide for weight loss in stimulant use disorder
This trial tests whether a weekly injection called tirzepatide (a diabetes and weight-loss medication) can help people with obesity and stimulant use disorder reduce stimulant use and lose weight. It aims to see if treating both conditions together improves outcomes.
Dallas, TexasAges 18–65 - NCT07640139Enrolling by invitation
Study of Weight-Loss Medications' Health and Cost Effects
This research study looks at how obesity medications affect people's health outcomes and healthcare costs. Researchers will track employees and their family members covered by participating Indiana employers to understand whether these medications help improve conditions like diabetes and heart health.
Indianapolis, IndianaAges 18–64 - NCT07638046RecruitingPhase 2
Mindful Walking and Brain Function in Older Adults
This study looks at how mindful walking—combining walking with focused attention—affects thinking and memory in older adults at risk for dementia. Researchers will track your brain activity and daily movement to see if this approach helps protect brain health.
Columbia, South CarolinaAges 60 years+ - NCT07624071RecruitingPhase 1
Testing ALN-6222 for weight management in adults
This Phase 1 trial tests a new medicine called ALN-6222 in people with obesity to see if it's safe and how well it works. The study focuses on adults with a BMI between 30 and 40 who don't have diabetes.
Mount RoyalAges 18–65 - NCT05281016Recruiting
Online family program to help children with weight
This study tests an online, family-based program (called the LITE Programme) to help children who are overweight. It may help improve healthy habits at home and support weight management.
SingaporeAges 6–12 - NCT07574723Recruiting
Tirzepatide dosing strategy to manage side effects in obesity
This study tests a new medication called tirzepatide, given at carefully adjusted doses, to help people with obesity lose weight while reducing unwanted side effects. Tirzepatide is a newer injectable medicine that helps control appetite and blood sugar.
Kuwait CityAges 18–100 - NCT07508020RecruitingPhase 1
How a new medicine affects appetite and metabolism in people with obesity
This study tests an experimental drug (NNC0487-0111) to see how it changes food intake, appetite, and the way your body processes food after meals. It is for adults with obesity who do not have diabetes.
BerlinAges 18–64 - NCT07495904Recruiting
Weight loss drug effects on body muscle with extra protein
This trial tests a weight-loss medication (GLP-1 receptor agonist) combined with dietary protein to see if it helps protect muscle while losing fat. It is for adults with obesity who are not taking certain other medications or supplements.
HeraklionAges 30–65 - NCT07419503Enrolling by invitation
Healthy lifestyle program for overweight children
This study evaluates a healthy lifestyle program for children ages 4 to 12 who are overweight. It looks at how well the program works and gathers feedback from children, parents, and program providers.
Rotterdam, South HollandAges 4–12 - NCT07332273RecruitingPhase 3
Levothyroxine for weight loss in obesity
This trial tests whether adding levothyroxine (a thyroid hormone) to a low-calorie diet helps people with obesity lose more weight. It is for adults aged 25-60 with a BMI of 30-39.9 who have either mild underactive thyroid or normal thyroid but higher thyroid hormone levels in the normal range.
CadizAges 25–60 - NCT06890169Recruiting
One-stop telehealth program for weight and diabetes
This trial tests a telehealth program that helps people lose weight and manage type 2 diabetes and fatty liver disease at the same time. It's a one-stop remote clinic that combines medical advice, nutrition, and lifestyle support.
SingaporeAges 21–70 - NCT07228741RecruitingPhase 2
Exercise and medicine for heart health in ALL survivors with obesity
This trial tests if combining resistance exercise with the weight-loss medication tirzepatide can improve heart and metabolic health in survivors of childhood acute lymphoblastic leukemia (ALL) who are now adults and have obesity or overweight with related health issues. You may benefit if you finished treatment at least 2 years ago and meet weight and health criteria.
Memphis, TennesseeAges 18 years+ - NCT07154719RecruitingPhase 4
Testing a weight loss drug's effect on muscle and bone
This study tests a medication called tirzepatide (a type of GLP-1 drug) to see how it affects muscle and bone health during weight loss. It is for people with obesity who are not menopausal and do not have diabetes or bone disease.
Baton Rouge, LouisianaAges 18–50 - NCT07144800Recruiting
Healthy eating and activity program for Hispanic families
This study tests a program to help Hispanic families with overweight or obesity eat healthier and be more active. It focuses on parents and their children aged 8-12, and may help improve family health.
New York, New YorkAges 18 years+ - NCT07103382Recruiting
Testing if a clay mineral helps with weight loss in obesity
This study tests if a natural clay mineral called attapulgite can help people with obesity or overweight and type 2 diabetes lose weight. It aims to see if it is safe and effective.
Changsha, HunanAges 18–60 - NCT07096908RecruitingPhase 4
Tirzepatide for weight loss in type 1 diabetes
This study tests a medication called tirzepatide for people with type 1 diabetes who also have overweight or obesity. Tirzepatide may help with weight loss and blood sugar control, and you'll use a continuous glucose monitor throughout the study.
Kuwait City, SharqAges 21 years+ - NCT07087808Recruiting
Family health program for teens with obesity in rural areas
This trial tests a virtual family intervention to help teens ages 12-17 with obesity and their primary caregiver (who is also overweight) improve health habits together. It's designed for families living in rural communities who both have a smartphone.
Charleston, South CarolinaAges 12–17
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Common questions
- Are there clinical trials for overweight or obese adults?
- Yes. Clin2 currently lists 800 recruiting overweight or obese adults studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a overweight or obese adults trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a overweight or obese adults trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.