Clinical trials
Overweight or Obese Adults clinical trials
Below are recruiting overweight or obese adults clinical trials, each written for real people, not researchers. We’re tracking 800 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06151015Recruiting
Dietary nitrate and calorie restriction for brain health
This study tests whether eating foods rich in dietary nitrates (like beets) combined with reducing calorie intake improves memory and blood vessel function in older adults.
Nottingham, NottinghamshireAges 60–75 - NCT07539415RecruitingPhase 1
Safety and effectiveness study of new injection in healthy adults
This study tests a new experimental injection in healthy volunteers to see if it's safe and how well the body absorbs it. Researchers will compare it with other similar treatments to understand how it works.
SeoulAges 19–64 - NCT07518875Enrolling by invitation
Online weight loss program for Arab adults
This study tests an online dietary weight loss program designed for Arabic-speaking adults. You'll receive 12 educational sessions over 6 months to help manage weight and improve health conditions like diabetes or high blood pressure.
Mecca, Mecca RegionAges 18–75 - NCT07447362Recruiting
Managing heart health risks in adults
This study checks if a program to manage heart health risks works better than usual care. If you have a risk factor like high blood pressure, diabetes, or smoking, you may qualify.
Santiago, Santiago MetropolitanAges 18 years+ - NCT07363616Recruiting
Health-focused programs for adults with higher body weight
This study tests different programs that focus on improving health without focusing on weight loss. It is for adults with higher body weight who want to feel healthier, not necessarily to lose weight.
Providence, Rhode IslandAges 18 years+ - NCT07336797RecruitingPhase 2
Empagliflozin for weight and metabolism in HIV
This trial tests if empagliflozin, a diabetes medicine, can improve weight and metabolism in people with HIV who take dolutegravir and have a high body mass index (BMI). It may help reduce weight gain linked to HIV treatment.
CairoAges 18–65 - NCT07282743RecruitingPhase 2
Study of GL0034 for overweight or obese adults with type 2 diabetes
This trial tests a new medication, GL0034, to see if it helps with weight loss and blood sugar control in people with type 2 diabetes who are overweight. Participants must already be taking metformin and not using other diabetes drugs.
Little Rock, ArkansasAges 18 years+ - NCT07221279Recruiting
Walking study for weight and heart health in adults
This study tests if a specific number of daily steps can help overweight or obese adults improve body composition and reduce heart disease risk. It's for people who are otherwise healthy but may have high blood pressure or joint pain managed by medication.
Kennesaw, GeorgiaAges 20 years+ - NCT07095543Recruiting
Plant-based weight loss through online program
This study tests an online weight loss program based on a plant-based diet. You may be able to join if you live in the U.S., are overweight, can travel to Washington DC for a body scan, and are not using weight loss medications.
Washington D.C., District of ColumbiaAges 18 years+ - NCT06897241Recruiting
How different starches affect your metabolism
This study tests how your body responds to different types of starch (quick, slow, and resistant). You will follow special diet plans and use monitoring devices to understand your personal metabolic reactions.
Gothenburg, Västra Götaland CountyAges 30–75 - NCT07065643Recruiting
Calorie restriction study for healthy overweight adults
This study looks at how sex hormones affect the benefits of a low-calorie diet in men and women of different ages. If you are a healthy overweight adult, the study may help understand how hormones and age influence weight loss results.
AberdeenAges 18–65 - NCT06961591Recruiting
Cooking skills for long-term weight loss in young adults with ID
This program teaches cooking skills to help young adults with intellectual disabilities lose weight and keep it off for 2 years. You’ll learn to prepare healthier meals with support from a family member or caregiver.
Kansas City, KansasAges 18–35 - NCT06949280Recruiting
Peanuts, weight loss, and bone health study
This study tests whether eating peanuts daily during weight loss affects bone health in adults aged 50 to 75.
New Brunswick, New JerseyAges 50–75 - NCT06938269RecruitingPhase 1
Study of MWN109 tablets in healthy adults
This trial tests a new tablet called MWN109 in healthy adults to see how safe it is and how the body handles it. It has two parts: one for people with a wide range of body weights, and another specifically for people with higher body weight. The results will help guide future studies.
Adelaide, South AustraliaAges 18–60 - NCT06824974Recruiting
Time-restricted eating for liver disease or cancer
This study tests whether combining time-restricted eating with healthy eating helps people with metabolic liver disease, cirrhosis, or early-stage liver cancer. If you are overweight and currently fast less than 12 hours at night, this diet approach might improve your health.
La Jolla, CaliforniaAges 18 years+ - NCT06724406Recruiting
Family weight loss program for Black adults
This study tests a family-centered weight loss program for Black adults and their family members. You and a family member or partner will work together to lose weight and improve health.
Chapel Hill, North CarolinaAges 18–75 - NCT06640179Recruiting
Lifestyle program for kidney transplant recipients
This study tests a diet and exercise program for people who recently received a kidney transplant. It aims to see if the program is safe and helpful for improving health after transplant.
Kansas City, KansasAges 18 years+ - NCT07845500RecruitingPhase 3
Monthly shot to help keep weight off after switching from semaglutide or tirzepatide
This study tests a new once-a-month medicine for people who have already been taking a weight-loss medication and want to keep the weight off. Participants will switch from their current medicine (semaglutide or tirzepatide) to the study drug.
Birmingham, AlabamaAges 18 years+ - NCT05770570RecruitingPhase 2
Diet and activity texting support for Mexican American drivers
This Phase 2 study tests a structured program using texts and recordings to help people improve diet and physical activity for weight loss. It focuses on specific Spanish-speaking groups and also includes a separate track for taxi/FHV drivers.
New York, New YorkAges 21 years+ - NCT05038683Recruiting
Child weight program study: new treatment vs usual care
This trial tests a structured obesity treatment program for children compared with the usual (conventional) approach. It may help your child get support to improve healthy weight habits.
Ballerup Municipality, BallerupAges 6–11 - NCT07677800Recruiting
Weight, lifestyle, and work performance in medical residents
This study looks at how weight, lifestyle, and changes in these areas affect the work performance and well-being of medical residents. If you join, you'll share information at the start and again after one year, and the results may help improve support for doctors in training.
Rome, RMAges Any age - NCT07595549RecruitingPhase 3
Testing Berobenatide for Weight Loss in Overweight Adults
This study tests a new medicine called berobenatide to help people with overweight or obesity lose weight. The medicine may also help improve related health conditions like high blood pressure, high cholesterol, or type 2 diabetes.
Canoga Park, CaliforniaAges 18 years+ - NCT07578584RecruitingPhase 1
Safety study of NNC0497-0040 in healthy and overweight adults
This early-stage study tests a new investigational medication in three groups: healthy adults with normal weight, adults who are overweight or obese, and men with type 1 diabetes who are also overweight. The research aims to understand how safe the medication is and how the body processes it.
NeussAges 18–55 - NCT07794579RecruitingPhase 3
Study of orforglipron for people with overweight at risk of health problems
This trial tests a new medicine, orforglipron, to help people with overweight who are at risk of developing weight-related health issues. It aims to see if the medicine can help with weight management and reduce risks before more serious conditions develop.
Anniston, AlabamaAges 18 years+
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Common questions
- Are there clinical trials for overweight or obese adults?
- Yes. Clin2 currently lists 800 recruiting overweight or obese adults studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a overweight or obese adults trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a overweight or obese adults trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.