Clinical trials
Overweight or Obese Adults clinical trials
Below are recruiting overweight or obese adults clinical trials, each written for real people, not researchers. We’re tracking 807 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06640179Recruiting
Lifestyle program for kidney transplant recipients
This study tests a diet and exercise program for people who recently received a kidney transplant. It aims to see if the program is safe and helpful for improving health after transplant.
Kansas City, KansasAges 18 years+ - NCT07282743RecruitingPhase 2
Study of GL0034 for overweight or obese adults with type 2 diabetes
This trial tests a new medication, GL0034, to see if it helps with weight loss and blood sugar control in people with type 2 diabetes who are overweight. Participants must already be taking metformin and not using other diabetes drugs.
Little Rock, ArkansasAges 18 years+ - NCT07336797RecruitingPhase 2
Empagliflozin for weight and metabolism in HIV
This trial tests if empagliflozin, a diabetes medicine, can improve weight and metabolism in people with HIV who take dolutegravir and have a high body mass index (BMI). It may help reduce weight gain linked to HIV treatment.
CairoAges 18–65 - NCT07363616Recruiting
Health-focused programs for adults with higher body weight
This study tests different programs that focus on improving health without focusing on weight loss. It is for adults with higher body weight who want to feel healthier, not necessarily to lose weight.
Providence, Rhode IslandAges 18 years+ - NCT07675590RecruitingPhase 1
Safety study of TIX100 in healthy volunteers
This study tests a new oral medication called TIX100 in healthy people to see if it is safe and how the body handles it. It is the first step in human testing, so it focuses on safety and side effects.
Chula Vista, CaliforniaAges 18–70 - NCT07447362Recruiting
Managing heart health risks in adults
This study checks if a program to manage heart health risks works better than usual care. If you have a risk factor like high blood pressure, diabetes, or smoking, you may qualify.
Santiago, Santiago MetropolitanAges 18 years+ - NCT07514260RecruitingPhase 1
Safety study of ABBV-295 injections in Japanese adults with overweight
This is an early-stage safety study testing a new injectable medication (ABBV-295) in healthy Japanese adults who are overweight or have obesity. The study measures how well the body tolerates the drug and how it moves through the body.
Anaheim, CaliforniaAges 18–65 - NCT07627074Recruiting
Real-world weight loss study with semaglutide
This study tracks how semaglutide (an injectable medication that reduces appetite) helps adults lose weight in everyday life. Researchers want to understand how well it works and how safe it is for people starting the treatment.
Seattle, WashingtonAges 18 years+ - NCT07518875Enrolling by invitation
Online weight loss program for Arab adults
This study tests an online dietary weight loss program designed for Arabic-speaking adults. You'll receive 12 educational sessions over 6 months to help manage weight and improve health conditions like diabetes or high blood pressure.
Mecca, Mecca RegionAges 18–75 - NCT05770570RecruitingPhase 2
Diet and activity texting support for Mexican American drivers
This Phase 2 study tests a structured program using texts and recordings to help people improve diet and physical activity for weight loss. It focuses on specific Spanish-speaking groups and also includes a separate track for taxi/FHV drivers.
New York, New YorkAges 21 years+ - NCT05038683Recruiting
Child weight program study: new treatment vs usual care
This trial tests a structured obesity treatment program for children compared with the usual (conventional) approach. It may help your child get support to improve healthy weight habits.
Ballerup Municipality, BallerupAges 6–11 - NCT07595549RecruitingPhase 3
Testing Berobenatide for Weight Loss in Overweight Adults
This study tests a new medicine called berobenatide to help people with overweight or obesity lose weight. The medicine may also help improve related health conditions like high blood pressure, high cholesterol, or type 2 diabetes.
Modesto, CaliforniaAges 18 years+ - NCT07578584RecruitingPhase 1
Safety study of NNC0497-0040 in healthy and overweight adults
This early-stage study tests a new investigational medication in three groups: healthy adults with normal weight, adults who are overweight or obese, and men with type 1 diabetes who are also overweight. The research aims to understand how safe the medication is and how the body processes it.
NeussAges 18–55 - NCT05277558Recruiting
MRI and brain testing in teens at risk for type 2 diabetes
This study looks at brain health in teens with normal weight, overweight, or obesity who are at risk for type 2 diabetes. It may help researchers understand how weight and diabetes risk affect the brain, using MRI scans and learning/memory tests.
St Louis, MissouriAges 12–17 - NCT07009171RecruitingPhase 2
Testing KDS2010 for weight loss in overweight or obese adults
This study tests a new medication called KDS2010 for people who are overweight or have obesity. The goal is to see if it helps with weight loss when combined with diet and exercise.
Suwon, Gyeonggi-doAges 18 years+ - NCT07075146RecruitingPhase 3
Comparing two HIV treatments for people with overweight or obesity
This trial compares two different daily pill combinations for people newly starting HIV treatment who are overweight or have obesity. It aims to see which one works better for controlling the virus and managing weight.
Mexico CityAges 18–70 - NCT07227051Recruiting
Phone app and fitness tracker for weight loss study
This study tests a smartphone app and fitness tracker to help people lose weight by monitoring their diet and activity. Participants get feedback and support through the app.
Milwaukee, WisconsinAges 18 years+ - NCT07229027Recruiting
Global overweight and obesity registry study
This study aims to develop better ways to measure how overweight or obesity affects your life, including severity, quality of life, and costs. You will fill out surveys to help researchers understand your experience.
Milton KeynesAges 18 years+ - NCT07255274Recruiting
Sleep help for teens with overweight or obesity
This study tests whether a behavior-based sleep program can help teenagers aged 13–17 who are overweight or have obesity and also have sleep problems. The goal is to see if improving sleep can help with weight management.
CovilhaAges 13–17 - NCT07340125Recruiting
Pistachio snacking and metabolic flexibility study
This study tests whether eating pistachios as a snack can improve how your body uses energy and manages metabolism. It looks at people who are overweight, sleep poorly, and don't exercise much.
Columbia, South CarolinaAges 25–45 - NCT07342855Recruiting
Healthy lifestyle program for children with obesity
This trial looks at how a community healthy lifestyle program helps children with obesity. Your family would join a program that supports healthy eating and physical activity, and researchers will track your child's progress.
Dallas, TexasAges 6–14 - NCT07628127RecruitingPhase 1
Study of VRB-103 with or without ecnoglutide for weight loss
This early-stage trial tests two experimental medications—VRB-103 alone or combined with ecnoglutide—to help people with overweight or obesity lose weight. Both drugs are designed to help control appetite and may offer a new treatment option if you qualify.
MelbourneAges 18–60 - NCT07654361RecruitingPhase 3
A new pill for weight loss in obesity and overweight
This study tests an investigational pill called aleniglipron to see if it helps people with obesity or overweight who also have a weight-related health problem (like high blood pressure) lose weight safely. It is a Phase 3 trial, meaning it is in the final stages before seeking approval.
Birmingham, AlabamaAges 18–79 - NCT07353931RecruitingPhase 3
Study of eloralintide for knee osteoarthritis pain in people with overweight or obesity
This trial tests an investigational drug called eloralintide to see if it can reduce knee pain in people with osteoarthritis who also have overweight or obesity. You may be able to join if you have knee osteoarthritis, a BMI of 27 or higher, and have tried to lose weight with diet before.
Mobile, AlabamaAges 18 years+
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Common questions
- Are there clinical trials for overweight or obese adults?
- Yes. Clin2 currently lists 807 recruiting overweight or obese adults studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a overweight or obese adults trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a overweight or obese adults trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.