Clinical trials
Overweight or Obese clinical trials
Below are recruiting overweight or obese clinical trials, each written for real people, not researchers. We’re tracking 1,530 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06181279Recruiting
Custom breathing machine settings for severe obesity
This trial is testing a personalized way to set the pressure in a breathing machine during surgery. The goal is to prevent lung collapse after surgery in patients with severe obesity.
Jinan, ShandongAges 18–60 - NCT06186869Recruiting
Diet and exercise for fatty liver disease
This study tests whether combining diet with two different exercise programs can help people who are overweight or obese and have fatty liver disease. The goal is to see which program works best to reduce liver fat and improve health.
Castellana Grotte, BariAges 18–65 - NCT06191848RecruitingPhase 4
Tirzepatide for obesity and knee osteoarthritis
This trial tests a once-weekly injection called tirzepatide to help people with obesity and severe knee osteoarthritis lose weight and potentially reduce knee pain. It may be a good option if you're already waiting for knee replacement surgery and have struggled to lose weight in the past.
Fitzroy, VictoriaAges 18 years+ - NCT06208345Recruiting
Early e-health support for kids with obesity
This study tests an e-health program for children with a very high BMI. It aims to help families manage weight early in life through online support.
BernAges 6–12 - NCT06252220RecruitingPhase 1
Testing a new drug for obesity in healthy adults
This trial tests a new medication called DA-1726 for people with obesity but no other major health problems. It aims to see if the drug is safe and how it works in the body. You may qualify if your body mass index (BMI) is between 30 and 45 and your weight has been stable for 3 months.
Miami, FloridaAges 18–65 - NCT06254261RecruitingPhase 2
RAY1225 for weight loss in obesity
This study tests an investigational medication called RAY1225 in people with obesity. It's given as an injection and may help with weight loss by targeting hormones that control appetite.
Beijingcun, HebeiAges 18–70 - NCT06254768Recruiting
Continuous glucose monitors for kids with obesity
This study tests if using a continuous glucose monitor (CGM), a small device that tracks blood sugar, can help children and teens with obesity understand their body better and improve their health.
Los Angeles, CaliforniaAges 10–21 - NCT06275061Recruiting
Obesity and metabolic surgery database study
This trial is building a database of people with obesity who have had or are planning to have weight loss surgery (metabolic or bariatric surgery). It helps doctors learn more about long-term results and safety.
Guangzhou, GuangdongAges Any age - NCT06288568Recruiting
Night shift work and obesity risk study
This study looks at how night shift work affects weight and health in hospital and factory workers. They want to see if working nights changes your body's hormones and risk for obesity.
Vienna, State of ViennaAges 21 years+ - NCT06292897Recruiting
Obesity and prostate cancer tissue study
This study looks at how obesity might affect prostate cancer growth. It uses tissue samples to understand the role of certain metabolites in the tumor, which could lead to better treatments.
MilanAges 18 years+ - NCT06299891RecruitingPhase 2
Study of weight loss medication for youth with hypothalamic obesity
This study tests a combination of two medications, phentermine and topiramate, to see if they help young people with hypothalamic obesity lose weight safely. Hypothalamic obesity is rapid weight gain caused by injury to the hypothalamus, often from a brain tumor or its treatment.
Philadelphia, PennsylvaniaAges 6–28 - NCT06303544Recruiting
Healthy eating and activity for Alaska Native preschoolers
This study tests a program to help Alaska Native preschoolers eat healthier and be more active. It aims to lower the risk of obesity by making small changes to daily routines at school and home.
Anchorage, AlaskaAges 3–5 - NCT06305273Recruiting
Face position study for obese patients during anesthesia
This study tests whether changing your head and body position helps with breathing mask ventilation before surgery in people with obesity.
Toronto, OntarioAges 18 years+ - NCT06309238Recruiting
Intensive diet vs. surgery for severe obesity
This study compares two programs for people with severe obesity: an intensive weight-loss diet and a weight-loss surgery (bariatric surgery). It aims to see which approach works better for long-term health.
AarhusAges 18–60 - NCT06316310Recruiting
Acupoint Thread Embedding for Weight Loss
This study tests a procedure called acupoint thread embedding to help women lose weight. It involves placing small threads under the skin at acupuncture points to stimulate weight loss.
Shanghai, Shanghai MunicipalityAges 18–45 - NCT06321458Recruiting
Intensive weight loss program vs. usual care for obesity
This trial compares an intensive weight loss program to usual care for adults with severe obesity and related health problems. It aims to see if a structured program helps people lose more weight and improve their health.
FrederiksbergAges 18–60 - NCT06323889Recruiting
Intermittent fasting study for adults with obesity
This study tests whether intermittent fasting (alternating periods of eating and fasting) can help with weight loss and health in adults with obesity. It aims to see if this approach is safe and effective.
Zurich, Canton of ZurichAges 18–50 - NCT07639021RecruitingPhase 2
Testing Different Dose Schedules of a New Weight Loss Medicine
This study tests a new injectable medication (NNC0662-0419) designed to help people with obesity lose weight. Researchers are comparing different ways of increasing the dose to find the safest and most effective approach.
Montgomery, AlabamaAges 18 years+ - NCT07091500Recruiting
Exercise and a weight-loss drug for people with obesity
This trial tests whether combining a GLP-1 medication (a type of diabetes drug that also helps with weight loss) with an exercise program can improve physical function in people with obesity. If you are obese and have trouble with daily activities, this study may help you become more mobile and healthier.
St Louis, MissouriAges 50–75 - NCT06335771Recruiting
Study on fat metabolism in obesity and diabetes
This study looks at how fat is processed in the body for people with different health conditions, including obesity and type 2 diabetes. It aims to find new ways to improve treatment by understanding these differences.
Columbia, MissouriAges 18–70 - NCT06335810Recruiting
Reducing obesity with a buddy program
This study explores whether having a friend or family member join you in a weight-loss program helps reduce obesity. You and your buddy will use a food-tracking app and get support from the program.
New York, New YorkAges 18 years+ - NCT06339320Recruiting
Stomach stitching for weight loss
This trial tests a non-surgical procedure called Endoscopic Sleeve Gastroplasty (ESG) to help people with obesity lose weight. A doctor uses a thin tube with a camera to stitch your stomach smaller, so you feel full sooner.
Houston, TexasAges 18 years+ - NCT06339840Recruiting
Lifestyle change for weight and fertility in obese men
This study tests whether a lifestyle program (diet and exercise) can help men with obesity lose weight and improve their chances of fathering a child through fertility treatment. You and your partner can join if you are an obese male, your partner has a healthy weight and regular periods, and you are both planning treatment at our center.
Zhengzhou, HenanAges 22–40 - NCT06341699Recruiting
Hormones in severe obesity
This study looks at hormone levels in people with severe obesity to understand how they differ from others. It may help explain how obesity affects the body.
Oggebbio, VerbaniaAges 18–80
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Common questions
- Are there clinical trials for overweight or obese?
- Yes. Clin2 currently lists 1,530 recruiting overweight or obese studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a overweight or obese trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a overweight or obese trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.