Clinical trials
Pain clinical trials
Below are recruiting pain clinical trials, each written for real people, not researchers. We’re tracking 3,263 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06290063RecruitingPhase 2
CBD for older adults who use cannabis
This study tests whether a pure CBD product (Epidiolex) can help older adults who use cannabis occasionally. It looks at how CBD affects people who already take medications for pain, sleep, or mood issues.
Boulder, ColoradoAges 60 years+ - NCT06291051Recruiting
Spinal cord stimulation for Parkinson's with painful bent spine
This study tests whether a spinal cord stimulator (a device that sends mild electrical pulses to the back) is safe and can reduce pain and improve the forward-bent posture in people with Parkinson's disease. It is for those whose bent posture has not improved with standard medication and is causing significant pain.
AmiensAges 18 years+ - NCT06291363RecruitingPhase 4
Esmolol for pain control during laparoscopic surgery
This trial tests a drug called esmolol to see if it helps control pain during and after laparoscopic surgeries that involve a small cut below the belly button. It may help people having a hysterectomy or left colon removal feel less pain during anesthesia.
Montreal East, QuebecAges 18–65 - NCT06294951Recruiting
Brain Scans for Bladder Pain Syndrome
This study uses brain scans (fMRI) to learn how bladder pain syndrome affects the brain. It compares women with bladder pain to those without, to better understand symptoms and improve future treatments.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT06297200Recruiting
Ultrasound treatment for complex back pain patients
This study tests a new, non-invasive ultrasound treatment for people with long-term back pain who also have opioid use disorder and anxiety. It aims to see if this gentle brain stimulation can reduce pain and improve quality of life.
Roanoke, VirginiaAges 18–65 - NCT06308328Recruiting
Mucosal contouring study for oral pain from radiation
This study tests a new way to reduce mouth and throat pain caused by radiation therapy for nasopharyngeal cancer. It may help if you are currently getting radiation or chemoradiation and have mouth sores.
Guangzhou, GuangdongAges 18 years+ - NCT06308029Recruiting
E-health pain self-management for breast cancer survivors
This trial tests an online program to help people manage lasting pain after breast cancer treatment. It's designed for those whose pain still gets in the way of daily life, even after finishing primary treatment.
AntwerpAges 18 years+ - NCT06312696Recruiting
Neck movement study with spinal manipulation therapy
This study tests whether a special hands-on therapy (spinal manipulation) can help people with long-term neck pain. It will measure how the neck moves and whether the treatment improves movement and reduces pain.
Minneapolis, MinnesotaAges 18–39 - NCT06315179Recruiting
Spatial gene study for inflammatory bowel disease
This study looks at tissue samples from people with suspected Crohn's disease, ulcerative colitis, or indeterminate colitis. The goal is to understand these conditions better and may lead to improved treatments.
Seattle, WashingtonAges 6–21 - NCT06316583Recruiting
Dry needling for painful periods study
This trial tests whether dry needling (a type of acupuncture) can help relieve primary dysmenorrhea (painful periods without another cause). It compares the effects on specific acupoints to see which works best.
Beijing, Beijing MunicipalityAges 18–30 - NCT06317870Recruiting
Nerve block vs spinal morphine for hip surgery pain
This trial compares two types of pain relief after a hip replacement: a nerve block (injecting numbing medicine near the hip) versus a small dose of morphine given through a spinal needle. It aims to find out which option works better with fewer side effects.
Lausanne, Canton of VaudAges 18 years+ - NCT06324942Recruiting
Nerve block for C-section pain relief
This study tests whether an extra nerve block (called a TAP block) given by your surgeon during a planned C-section can provide better pain relief than standard care alone. Researchers want to see if it reduces the need for stronger pain medicines after delivery.
Calgary, AlbertaAges 18 years+ - NCT07695935Recruiting
Pain relief after hernia repair: nerve block vs low-dose morphine
This study compares two ways to manage pain after open inguinal hernia repair: a nerve block (injection near the abdominal muscles) versus a low-dose painkiller (morphine) given through the spinal needle. The goal is to find which method provides better relief with fewer side effects.
ÇorumAges 18–80 - NCT05585788Recruiting
Opioid pain device test for cancer surgery patients
This study tests a device that helps you safely use opioid (strong pain) medicine after major cancer surgery. It may help improve post-surgery pain control while tracking how people use the medicine.
New York, New YorkAges 18–99 - NCT07553273Recruiting
Vibration to reduce pain from steroid hand and arm injections
This study tests whether applying gentle vibration during steroid injections into the hands, wrists, or elbows can reduce injection pain. If vibration works, it could make these commonly prescribed treatments more comfortable for patients.
Galveston, TexasAges 18 years+ - NCT06330779Recruiting
Trauma-adapted yoga for teens with PTSD or ADHD
This trial tests if a special yoga program helps teenagers with PTSD or ADHD feel better. It is designed to be safe and supportive for their mental health.
GothenburgAges 12–18 - NCT06332495Recruiting
Bedpan comfort study for bedridden patients
This study looks at how comfortable and safe bedpans are for patients and caregivers. It aims to find ways to reduce pain and skin irritation for people who are bedridden.
Nantes, Loire AtlantiqueAges 18 years+ - NCT06332560Recruiting
Endometriosis pain and lifestyle
This study looks at how diet and lifestyle changes, including cognitive behavioral therapy (a type of talk therapy), might help reduce pain from endometriosis. You would follow a special diet and attend therapy sessions while researchers track your symptoms.
's-HertogenboschAges 17 years+ - NCT06336733RecruitingPhase 3
Trial of anakinra for FMF attacks in patients who refuse daily shots
This trial tests if taking anakinra (a targeted medicine) only when you have a painful FMF attack can help, instead of taking it every day. It is for people with Familial Mediterranean Fever (FMF) whose attacks continue despite taking colchicine, and who do not want daily injections.
ParisAges 6 years+ - NCT06341270Recruiting
Electric acupressure for pain after liver surgery
This trial tests if a gentle electric stimulation on the skin (TEAS) can reduce pain and speed up recovery after liver surgery. The treatment is non-invasive and may be an alternative to pain medicines.
Chengdu, SichuanAges 18–80 - NCT06346132Recruiting
Does virtual reality help during heart device surgery?
This study tests if wearing a virtual reality headset during a heart device implant or battery change helps you feel more comfortable and relaxed. The surgery is done under local anesthesia (numbing medicine) while you stay awake, and you go home the same day.
Lugano, Canton TicinoAges 18 years+ - NCT06350409Recruiting
Opioid use after surgery in teens
This study looks at how teens aged 12–17 use opioids after a scheduled surgery. It aims to understand outcomes and help improve pain management.
Aurora, ColoradoAges 12–17 - NCT06353789Recruiting
Teen Period Pain and Future Health
This study at the University of Oxford is looking at whether painful periods in teenagers can lead to long-term pain. You will be asked about your period pain and may have an MRI scan of your brain (safe, no radiation). The goal is to find ways to prevent chronic pain later in life.
Oxford, OxfordshireAges 11–20 - NCT06355271Recruiting
Pain relief and recovery after planned C-section
This trial studies how well pain is controlled and how quickly women recover after a planned C-section under spinal anesthesia. It compares different pain relief methods to find the best approach.
BellinzonaAges 18 years+
Hear when a new Pain trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for pain?
- Yes. Clin2 currently lists 3,263 recruiting pain studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a pain trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a pain trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.