Clinical trials
Pain clinical trials
Below are recruiting pain clinical trials, each written for real people, not researchers. We’re tracking 3,138 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06902636Recruiting
Trauma care program for older adults living alone
This trial tests a special care program for older adults who live alone and have limb injuries. It aims to help them recover safely at home using smartphone support for three months.
Kaohsiung City, KaohsiungAges 65 years+ - NCT06903442Recruiting
Helping ER chest pain patients understand heart risk
This study is testing a new way to talk with people about their heart health after they come to the Emergency Room with chest pain. It aims to help you understand your risk and what you can do to prevent future problems.
EdinburghAges 18 years+ - NCT06902805RecruitingPhase 2/Phase 3
Testing botox injections and splints for thumb arthritis pain
This study tests if botox injections into the thumb joint, along with a custom splint, can reduce pain from thumb base arthritis. It may be an option if you have persistent pain and have not had recent thumb surgery or certain other treatments.
Paris, Île-de-France RegionAges 18 years+ - NCT06906939RecruitingEarly Phase 1
Brain stimulation and tai chi for knee arthritis and depression
This pilot study tests if combining brain stimulation (rTMS) with Tai Chi can help knee arthritis pain and improve depression. It compares these two treatments to see which works better for people with both pain and low mood.
Los Angeles, CaliforniaAges 50–95 - NCT04242589RecruitingPhase 2
Radiation plus bone cement for painful spinal metastasis pain
This trial tests adding a bone-cement procedure (vertebroplasty) along with radiation to reduce pain from cancer that has spread to the spine. It is for adults with painful metastatic (spread) tumors in the middle or lower spine, without current spinal cord pressure.
Edmonton, AlbertaAges 18 years+ - NCT04832100Recruiting
Study of a fat marker in fibromyalgia
This study looks at whether a specific fat-related marker (called LPC16:0) is linked to fibromyalgia. Your participation could help researchers understand what role this marker may play in the condition.
Kaohsiung CityAges 18–70 - NCT05271331Recruiting
Numbing injection options for back surgery pain
This trial compares two ways of numbing tissue during a planned back surgery called a laminectomy: an “ESPB block” versus numbing the wound directly. It aims to see which method works better for pain control and comfort after surgery.
Padova, VenetoAges 18 years+ - NCT06798155Recruiting
Music to prevent pain after anal surgery
This study tests whether listening to a specific set of music before and after surgery for hemorrhoids, fistula, or anal fissure can help reduce pain. You would use a phone or tablet app to listen to short music sessions.
Saint-DenisAges 18 years+ - NCT06308029Recruiting
E-health pain self-management for breast cancer survivors
This trial tests an online program to help people manage lasting pain after breast cancer treatment. It's designed for those whose pain still gets in the way of daily life, even after finishing primary treatment.
AntwerpAges 18 years+ - NCT06891690Recruiting
Brain stimulation for neurological and gynecological conditions
This trial tests whether a gentle brain stimulation technique called tDCS can help people with neurological problems (like weakness in arms or legs) or certain gynecological conditions (like endometriosis or painful periods) who are not using other treatments. It aims to see if tDCS can improve symptoms.
PoznanAges 18–90 - NCT06892743Recruiting
Comparing two pain blocks for kidney removal surgery
This trial compares two ultrasound-guided nerve blocks to see which one provides better pain relief for patients undergoing open kidney removal (nephrectomy). If you have kidney cancer and are scheduled for this surgery, you may be able to join.
Maadi, Cairo GovernorateAges 18–70 - NCT06640231Recruiting
Sealer activation for reducing pain after root canal
This trial tests if activating a sealer inside a tooth after root canal can reduce pain in the days after treatment. It may help people with a painful lower molar that still has a live nerve.
Cairo, New CairoAges 18–40 - NCT06566950Recruiting
Blood flow training for leg muscle health in athletes
This study tests a training method that uses light blood flow restriction to improve leg muscle structure. It is for young athletes (ages 15–35) who play high-level sports like martial arts, basketball, soccer, or futsal at least twice a week.
Denpasar, BaliAges 15–35 - NCT06879860Enrolling by invitation
Comparing stitch vs no stitch for groin hernia repair
This study compares two ways to fix a mesh during groin hernia surgery: 3D patch with one stitch versus no stitches at all. It aims to see which method leads to less long-term pain and fewer hernias coming back. If you have a first-time, moderately large groin hernia, you may qualify.
Nanchong, SichuanAges 18–80 - NCT06884865RecruitingPhase 2
Study of an experimental knee injection for osteoarthritis pain
This study tests a new investigational medicine injected into the knee to see if it is safe and tolerable for people with painful knee osteoarthritis. It may help reduce pain and improve knee function.
Birmingham, AlabamaAges 45–80 - NCT06885931Recruiting
Nerve stimulation trial for mixed urinary incontinence
This trial tests a new implant that stimulates a nerve in your pelvic area to help control both stress and urge urine leaks. It might be an option if you've tried other treatments like bladder training or medicine and they didn't help enough or caused side effects.
Leuven, Herestraat 49Ages 22 years+ - NCT06887608Enrolling by invitation
Partner-Assisted Rebozo for Birth Comfort
This study tests a partner-assisted rebozo technique — a gentle way to help ease pain and fear during labor. Your partner wraps a scarf around your belly and sways it rhythmically, with guidance from a nurse, to make you more comfortable.
Zeytinburnu, IstanbulAges 18 years+ - NCT06884332Recruiting
Spinal radiation for bone pain from cancer
This trial tests a specific type of radiation therapy for bone pain caused by cancer that has spread to the spine. It aims to improve pain relief and quality of life.
Brest, BrestAges 18 years+ - NCT06880484Enrolling by invitation
Far-infrared socks for diabetic nerve pain
This study tests whether special far-infrared socks can help relieve nerve pain and improve nerve function in people with diabetic nerve damage. If you have mild to moderate nerve pain and live in Kayseri, you may be able to join.
Talas, KayseriAges 19 years+ - NCT06886633Enrolling by invitation
Breathing exercise and cold pack for wound cleaning pain
This study tests whether a simple breathing exercise and a cold pack can help reduce pain and anxiety while a wound is being cleaned (called sharp debridement). If you are having a wound cleaned and feel anxious about it, this may be a way to feel more comfortable.
Gaziantep, GaziantepAges Any age - NCT04423874Recruiting
Tests how unpleasant sounds change pain tolerance
This study tests whether hearing unpleasant, non-verbal sounds changes how much pain you can tolerate. It may help researchers understand how stress and sound affect pain experiences.
Saint-EtienneAges 18–60 - NCT06872567Recruiting
Knee artery block vs. steroid injection for arthritis pain
This study compares two treatments for knee arthritis pain: a procedure that blocks blood flow to the painful area (genicular artery embolization) versus a steroid injection into the knee joint. The goal is to see which one provides better pain relief.
Charlottesville, VirginiaAges 40 years+ - NCT06874452RecruitingPhase 4
Anti-anxiety pill for second cataract surgery
This study tests if giving the anti-anxiety pill alprazolam (XANAX) before your second cataract surgery helps reduce anxiety and improve satisfaction with the procedure.
TaipeiAges 18–80 - NCT06878417Recruiting
Cannabinoids for osteoarthritis knee or hip pain
This study tests if cannabinoid medications can reduce pain interference in daily life for people with hip or knee osteoarthritis. It may be a new option for moderate to severe pain.
Toronto, OntarioAges 40–80
Hear when a new Pain trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for pain?
- Yes. Clin2 currently lists 3,138 recruiting pain studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a pain trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a pain trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.