Clinical trials
Pain clinical trials
Below are recruiting pain clinical trials, each written for real people, not researchers. We’re tracking 3,263 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07665086Enrolling by invitation
Isometric exercise for rheumatoid arthritis
This study tests whether simple isometric (holding still) exercises can help people with rheumatoid arthritis. The goal is to see if these exercises improve hand function and quality of life.
DenizliAges 18–65 - NCT07658521Enrolling by invitation
Nerve blocks for pain after heart bypass surgery
This study tests whether adding two numbing injections (nerve blocks) to standard care provides better pain relief after heart bypass surgery. It is for adults having planned surgery and compares pain scores and recovery.
Cairo, Cairo GovernorateAges 18–75 - NCT07626684Enrolling by invitation
Ice Pack After Minimally Invasive Hysterectomy Surgery
This study tests whether applying ice packs to the abdomen after a minimally invasive hysterectomy (removal of the uterus through the vagina) helps reduce pain and speed recovery. You would be randomly assigned to either receive ice pack treatment or standard care.
MuğlaAges 48–70 - NCT07624929Enrolling by invitation
Virtual Reality to Reduce Anxiety During Varicose Vein Treatment
This study tests whether wearing a virtual reality headset during varicose vein treatment (a minimally invasive laser procedure on your legs) can help reduce anxiety and pain. You'd use VR while the doctor treats the problematic veins under local anesthesia.
BydgoszczAges 18 years+ - NCT07615595Enrolling by invitationPhase 4
Dexamethasone to reduce side effects from spinal anesthesia during cesarean delivery
This study tests whether giving a steroid medication (dexamethasone) before spinal anesthesia can reduce uncomfortable side effects like nausea, vomiting, and low blood pressure during planned cesarean delivery. The goal is to help you feel better during and after your surgery.
Ho Chi Minh City, Ho Chi MinhAges 18 years+ - NCT07606638Enrolling by invitation
Pain Relief Options for Oral Cancer Patients
This study compares two different pain management approaches for people with oral cancer: opioid medication versus a combination of pregabalin (a nerve pain reliever) and naproxen sodium (an anti-inflammatory painkiller). The goal is to see which approach works better and is safer for controlling cancer-related pain.
Lahore, Punjab ProvinceAges 18 years+ - NCT07576985Enrolling by invitation
IV Tylenol for Pain and Agitation After Throat Surgery in Young Children
This study tests whether giving acetaminophen (Tylenol) through an IV (a vein) instead of by mouth helps reduce pain and fussiness after tonsil and adenoid removal in children age 7 and under. The goal is to find better ways to keep children comfortable during recovery.
Cleveland, OhioAges Up to 8 years - NCT07575230Enrolling by invitationPhase 4
Pain relief after skin cancer surgery: new drug vs standard
This study compares a new pain medication (suzetrigine) to a common pain reliever (Norco) for people recovering from Mohs micrographic surgery, a specialized procedure to remove skin cancer. The goal is to see if the new medication works better and is safer for post-surgery pain.
Dallas, TexasAges 18–89 - NCT07561489Enrolling by invitation
Study of OsteoPearl Implants for Spine Fractures
This study observes how a biological implant called OsteoPearl helps people recover from recent spine fractures in the mid or lower back. Researchers will track your pain relief and ability to function over time after a minimally invasive procedure to stabilize the fracture.
Williamsville, New YorkAges 50 years+ - NCT07545850Enrolling by invitation
Virtual Reality Glasses to Reduce Pain During IUD Insertion
This study tests whether wearing virtual reality glasses during an IUD insertion procedure can help reduce pain and anxiety. You would wear the glasses during the procedure to see if they help you feel calmer and experience less discomfort.
MalatyaAges 18–49 - NCT07540663Enrolling by invitation
Stem cells to improve spinal cord stimulation pain relief
This trial tests whether stem cells injected near your spinal cord can improve pain relief from your existing spinal cord stimulator (BurstDR device). You're only eligible if your current stimulator is already helping with at least 50% pain reduction.
Hasselt, LimburgAges 18 years+ - NCT07535879Enrolling by invitation
Neck Pain Treatment Using Pressure Feedback for Teachers
This study tests whether using pressure feedback (a device that gives you information about muscle tension) while doing neck exercises helps reduce neck pain in teachers. Researchers want to see if this technique strengthens deep neck muscles and improves your symptoms.
Istanbul, KüçükçekmeceAges 22–65 - NCT07532876Enrolling by invitationPhase 4
Elagolix versus birth control pills for endometriosis pain
This study compares two medications—elagolix (a newer hormone treatment) and birth control pills—to see which works better at reducing pelvic pain caused by endometriosis. Endometriosis is a condition where tissue similar to the uterine lining grows outside the uterus, often causing painful periods.
Rawalpindi, Punjab ProvinceAges 18–45 - NCT07527065Enrolling by invitation
Pain Relief Methods for Hernia Surgery Recovery
This study compares two different nerve-blocking injection techniques to help manage pain after open inguinal hernia repair surgery. The goal is to determine which method works better to keep you comfortable during recovery.
ÇorumAges 18–65 - NCT07513012Enrolling by invitation
Pain Relief Methods After Gallbladder Removal Surgery
This study compares two ways of numbing the abdomen during gallbladder removal surgery to see which one works better for pain relief. One method numbs one side of your belly, and the other numbs both sides.
Lahore, Punjab ProvinceAges 18–80 - NCT07493434Enrolling by invitation
Can essential oils help with migraine pain?
This trial tests if inhaling essential oils can reduce pain in people with migraine. You may join if you have migraines and are not allergic to essential oils.
São Paulo, São PauloAges 18–60 - NCT07486609Enrolling by invitation
Comparing tests for jaw joint pain diagnosis
This study compares two different ways to diagnose jaw joint (TMJ) problems: a jaw-motion analyzer and an MRI. It aims to see which method is more accurate for people with ongoing face or jaw pain.
CairoAges 18–50 - NCT07477847Enrolling by invitation
Custom exercise for back pain, posture, and quality of life
This study tests a personalized exercise program to see if it reduces back pain, improves posture (kyphosis angle), and boosts quality of life. It may help if you have nonspecific back pain and haven't been exercising regularly.
IstanbulAges 18–45 - NCT07463430Enrolling by invitationPhase 4
Suzetrigine for pain after non-mastectomy breast surgery
This trial tests a new pain medication, suzetrigine, for people having breast surgery (not mastectomy) who are expected to have moderate pain. It checks if this drug works well compared to standard options.
San Diego, CaliforniaAges 18 years+ - NCT07432074Enrolling by invitation
Acupressure and massage after cesarean section
This study tests whether acupressure (gentle pressure on specific points) or massage can help women recover after a planned cesarean. It aims to reduce pain and improve comfort without using extra medicine.
IstanbulAges 18–45 - NCT07404813Enrolling by invitation
Do family voices affect brain chemistry and pain in ICU patients?
This study tests whether hearing a family member's voice can change natural brain chemicals (dopamine and serotonin) and reduce pain for people in the intensive care unit who are in a coma but can still react. It may help improve comfort during recovery.
Malatya, MalatyaAges 18–65 - NCT07393503Enrolling by invitationPhase 4
Pain relief for new muscle and joint injuries
This trial compares two common treatments for new muscle or joint pain: an over-the-counter pain reliever (Tylenol and ibuprofen) versus an oral steroid (a stronger anti-inflammatory medication). The goal is to see which option works better for short-term pain and recovery.
Buffalo, New YorkAges 18 years+ - NCT07368738Enrolling by invitationPhase 4
IV Pain Meds for Shock Wave Lithotripsy
This study tests whether giving two pain relievers—acetaminophen (Tylenol) and ketorolac (an anti-inflammatory)—through an IV during shock wave lithotripsy helps control pain better than standard care. You may qualify if you need this kidney stone procedure and don't have certain health conditions.
Saint John, New BrunswickAges 19 years+ - NCT07362407Enrolling by invitation
Cannabinoid treatment study for patients in Brazil
This study tracks how cannabis-based medicines work in real life. It looks at how people feel and function while using these treatments prescribed by their doctor.
Florianópolis, Santa CatarinaAges 18 years+
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Common questions
- Are there clinical trials for pain?
- Yes. Clin2 currently lists 3,263 recruiting pain studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a pain trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a pain trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.