Clinical trials
Pain clinical trials
Below are recruiting pain clinical trials, each written for real people, not researchers. We’re tracking 3,138 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07429916RecruitingEarly Phase 1
Ketamine for shoulder pain after weight loss surgery
This trial tests if a single dose of ketamine, given during surgery, can reduce common shoulder pain after laparoscopic gastric sleeve surgery. If you are having this weight-loss procedure and meet the weight and health criteria, this study may help improve your recovery.
IrbidAges 18–60 - NCT07431632Recruiting
Nerve freezing vs. epidural for pain after pectus excavatum repair
This study compares two ways to manage pain after pectus excavatum surgery: freezing the nerves during surgery (cryoanalgesia) versus an epidural block. The goal is to see which method provides better pain relief with fewer side effects.
São Paulo, São PauloAges 13 years+ - NCT07427537Recruiting
Studying nerve damage from chemotherapy in colorectal and lung cancer patients
This study looks for small molecules in the blood that might predict nerve damage caused by certain chemotherapies. If you have colorectal or lung cancer and are starting a specific chemo plan, this trial could help researchers understand why some people get nerve problems and others don't.
Clermont-FerrandAges 18 years+ - NCT07432841Recruiting
Personalized brain stimulation for chronic pain
This trial tests a personalized form of brain stimulation (high-definition tDCS) to treat chronic pain that has not improved with other treatments. If you have had pain for at least 6 months and it is still moderate to severe, this may be an option to explore.
MilanAges 18–75 - NCT07426367Recruiting
Online therapy for chronic pain and emotional distress
This trial tests an online therapy program that uses acceptance and commitment therapy (ACT) to help people with chronic pain who also feel anxious or depressed. The goal is to improve emotional well-being and daily functioning.
LundAges 18–65 - NCT06811077Recruiting
Health coaching by a patient expert for chronic pain
This trial tests whether one-on-one coaching sessions led by a trained patient expert can help people better manage chronic pain. If you already attend a chronic pain clinic and are open to learning new coping skills, this program may support you.
Paris, FranceAges 18 years+ - NCT06816082Recruiting
Online therapy for chronic pain rehabilitation
This trial tests if adding internet-based acceptance therapy to standard pain rehabilitation helps adults with chronic pain. It is for patients at the Linköping pain clinic who have internet access.
Linköping, Östergötland CountyAges 18 years+ - NCT07424638Recruiting
Nerve blocks for shoulder pain after lung surgery
This trial compares two types of nerve blocks to prevent shoulder pain after lung cancer surgery. If you are having open-lung surgery for lung cancer, you may be able to join.
CairoAges 18–65 - NCT07423377Recruiting
Vibration device for fibromyalgia pain
This trial tests if a device that delivers small vibrations to your ear can help reduce pain from fibromyalgia. You'll use the device as directed and answer online questions about your pain before and after.
New York, New YorkAges 18 years+ - NCT07418632Recruiting
Motion training for neck pain using smart classification
This study tests a special motion-training program for people with neck pain. It uses a computer to classify and guide your movements, which may help reduce pain better than usual care.
LjubljanaAges 18–65 - NCT07421427Recruiting
Preventing pain after mastectomy with added medication
This trial tests if adding amantadine or duloxetine to the standard drug pregabalin can better prevent chronic pain after a mastectomy. It may help you if you're undergoing a modified radical mastectomy for breast cancer.
CairoAges 18–65 - NCT07410000Recruiting
Block for pain after hip replacement
This trial tests a nerve block to reduce pain after hip replacement surgery. It may help you need fewer painkillers and recover more comfortably.
BursaAges 18–80 - NCT07413055RecruitingPhase 3
Comparing two doses of dexamethasone for dental implant pain
This study tests whether a higher dose of dexamethasone (8 mg) works better than a lower dose (4 mg) for reducing pain after getting a single dental implant. It may help find the best way to manage discomfort after surgery.
MuscatAges 21–80 - NCT06784089Recruiting
Hip fracture type, nutrition and pain after surgery
This study looks at how a person's nutrition before hip surgery relates to their pain levels after surgery. It aims to help doctors improve recovery for older adults.
AnkaraAges 65 years+ - NCT07413107Recruiting
Italian version of a back pain disability questionnaire
This study is testing a new Italian questionnaire that measures how much low back pain affects your daily life. It's for people who have had low back pain for at least 3 months and speak Italian.
Lissone, MilanoAges 18–90 - NCT07411859Recruiting
Reboot Pain: Brain stimulation for chronic pain
This trial uses a gentle brain stimulation technique called tDCS to see if it can reduce chronic pain in people with certain pain conditions. You would self-administer the treatment and report your results.
Atlanta, GeorgiaAges 18–89 - NCT07415941Recruiting
Mindfulness and nerve stimulation for back pain and depression
This trial tests if combining mindfulness-based meditation with a gentle nerve stimulation device (applied to the ear) can help people aged 50–85 with chronic low back pain and depression. The goal is to reduce pain and improve mood without changing your current medications.
Tallahassee, FloridaAges 50–85 - NCT07411417Recruiting
Acupressure for pain and lung function after chest surgery
This trial tests if acupressure can help reduce pain and improve lung function after a first-time chest surgery. It may offer a non-drug way to support recovery.
IstanbulAges Any age - NCT07408193RecruitingEarly Phase 1
Lidocaine and ketamine for severe cancer pain not helped by opioids
This trial tests if adding lidocaine and ketamine to your current pain medicines can better control severe cancer-related pain that opioids alone haven't helped.
Athens, AtticaAges 18 years+ - NCT06817135Recruiting
Shoulder exercises for breastfeeding neck pain
This trial tests if special shoulder-blade (scapular) exercises can help reduce neck pain in mothers who are exclusively breastfeeding. The exercises are simple and designed to strengthen the muscles that support your neck while you hold your baby.
Giza, DokkiAges 18–35 - NCT03877653Recruiting
Freedom-1 treatment for long-term knee pain in adults
This study tests a procedure called Freedom-1 to reduce long-term, limiting knee pain from knee arthritis. It may help if other non-surgical options didn’t work and you meet specific knee and health requirements.
Placentia, CaliforniaAges 18 years+ - NCT05817591Recruiting
Testing how high-dose capsaicin affects nerve pain
This study looks at what “response profiles” different people have after treatment with high-concentration capsaicin for nerve-related pain. It may help doctors predict who benefits from capsaicin by measuring changes in symptoms and nerve sensitivity.
AnnecyAges 18 years+ - NCT06495632RecruitingPhase 4
Scheduled or as-needed pain medicine after surgery?
This study compares taking pain medicine on a fixed schedule versus only when you need it after common outpatient surgeries. It aims to find which approach works better for controlling pain and reducing side effects.
Fayetteville, North CarolinaAges 18–65 - NCT07401147Recruiting
TENS for pain relief during first labor
This trial tests a gentle electrical device (TENS) to help manage pain during labor. It's for women having their first baby, with a healthy, single pregnancy, and no major health issues.
Tegucigalpa, Francisco Morazán DepartmentAges 18–45
Hear when a new Pain trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for pain?
- Yes. Clin2 currently lists 3,138 recruiting pain studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a pain trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a pain trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.