Clinical trials
Pain clinical trials
Below are recruiting pain clinical trials, each written for real people, not researchers. We’re tracking 3,142 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07612761Recruiting
Pain Relief Methods for Hip Fracture Surgery
This trial compares two different nerve-blocking techniques to help manage pain after hip fracture surgery. Both methods numb the area around your hip to reduce pain and may help you recover better.
Istanbul, IstanbulAges 18 years+ - NCT07620353Recruiting
Study of OROSEDAL for sore throat and mouth sores
This study observes how well OROSEDAL, a topical oral medication, works for sore throats and minor mouth ulcers or sores that have lasted less than 15 days. You'll be asked to track your pain relief while using the product your doctor prescribes.
Multiple LocationsAges 8 years+ - NCT07618247RecruitingPhase 1
Testing a new drug in healthy adults
This is an early-stage study testing a new investigational drug called IG001119 in people who are in good health. Researchers will give increasing doses to small groups to learn how the drug is processed by the body and to check for any side effects.
Adelaide, South AustraliaAges 18–65 - NCT06695312Recruiting
High Tone Power Therapy for Neck Pain and Body Awareness
This trial tests a type of physical therapy called High Tone Power Therapy for people with long-term neck pain from a herniated disc in the neck. It aims to reduce pain and improve your sense of where your neck is in space (proprioception) without needing surgery.
Giza, Giza GovernorateAges 35–50 - NCT06707857Recruiting
TNT Treatment for Rotator Cuff Tendon Pain
This study tests if a treatment called TNT can reduce shoulder pain, improve movement, and help with daily activities in people with rotator cuff tendon problems. It may be a good option if you've had shoulder pain for at least three months.
Lahore, Punjab ProvinceAges 18–65 - NCT06707363Recruiting
Psychological factors and pain after orthopedic surgery
This study looks at how your thoughts and feelings affect your pain after orthopedic surgery. Researchers want to understand these factors to improve care for future patients.
Krakow, MalopolskaAges 18–65 - NCT05008185Recruiting
Nerve interface surgery to reduce hand pain nerve tumors
This trial tests a regenerative nerve device/surgery approach to reduce painful nerve growths (neuromas) after a finger or partial hand amputation. You may qualify if you’re an adult with confirmed, localized neuroma pain and have already tried a 6-week desensitization therapy plan.
Baltimore, MarylandAges 18 years+ - NCT03596424Recruiting
Testing ketamine and dexmedetomidine during lung surgery
This trial studies whether the anesthesia medicines ketamine and dexmedetomidine can improve care during elective lung (video-assisted) surgery. It may help with comfort during and after the operation, depending on how these medicines affect pain and recovery.
Montreal, QuebecAges 18–80 - NCT07603934RecruitingEarly Phase 1
Testing Medications Inside Root Canals to Reduce Pain
This study tests different medications placed inside a tooth's root canal during treatment to see which one best reduces pain afterward. If you have a tooth with a dead nerve (necrotic pulp), this trial might help determine the best way to manage your pain during the healing process.
Cairo, Cairo GovernorateAges 18–40 - NCT07608939Recruiting
Pain relief after root canal treatment with different sealers
This study compares how much pain you experience after root canal treatment depending on which type of sealing material is used. Root canal treatment removes infected tissue from inside a tooth; this trial helps dentists find the approach that causes the least post-treatment discomfort.
LefkaAges 18–60 - NCT07603960Recruiting
Cold therapy to ease endometriosis pelvic pain
This study tests whether exposing your whole body to very cold air (below freezing) can reduce chronic pelvic pain from endometriosis and improve your quality of life. Endometriosis is a condition where tissue similar to the uterine lining grows outside the uterus, often causing pain.
Edinburgh, ScotlandAges 16 years+ - NCT07606638Enrolling by invitation
Pain Relief Options for Oral Cancer Patients
This study compares two different pain management approaches for people with oral cancer: opioid medication versus a combination of pregabalin (a nerve pain reliever) and naproxen sodium (an anti-inflammatory painkiller). The goal is to see which approach works better and is safer for controlling cancer-related pain.
Lahore, Punjab ProvinceAges 18 years+ - NCT07605754Recruiting
Nerve Surgery Results for Pain After Amputation
This study evaluates how well nerve surgery works for patients with severe, persistent pain in the area where a limb was amputated. Researchers will review outcomes to understand if this surgical approach helps reduce pain that hasn't responded to other treatments.
Leiden, South HollandAges 18 years+ - NCT07603921Recruiting
Local Pain Relief Injection During Lung Surgery
This study tests whether injecting a numbing medicine and anti-inflammatory steroid around the surgical area before lung surgery reduces pain after the procedure. If it works, it could help patients recover more comfortably after thoracoscopic lung surgery (minimally invasive lung surgery using small cameras).
Beijing, Beijing MunicipalityAges 18–64 - NCT07611643Recruiting
Treating Jaw Clenching and Facial Pain With a Custom Bite Guard
This study tests whether a custom-made bite guard (called an occlusal splint) can help relieve jaw and facial pain caused by temporomandibular disorders—conditions affecting the jaw joint and muscles. Researchers will monitor how well the treatment works and how it affects your symptoms.
Roma, RomaAges 18 years+ - NCT05279963Recruiting
Study for bladder pain using a nerve-based treatment (EA)
This trial tests whether a nerve-based therapy called EA can reduce bladder pain. It also aims to understand why the treatment may help by looking at underlying mechanisms.
Hangzhou, ZhejiangAges 18–70 - NCT06519136Recruiting
Second level Reiki for pain and quality of life in dialysis
This study tests whether a second level of Reiki (a gentle energy healing practice) can help reduce pain and improve quality of life for people on dialysis. If you already received Reiki level 1 in a previous round of this study, you may be able to join.
ÇorumAges 28–84 - NCT07603323Recruiting
Pain Relief Methods for Meniscus Knee Surgery
This study compares two different numbing techniques (ACB and ACB combined with BiFeS) to see which one better controls pain after meniscus surgery. The meniscus is cartilage in your knee that can tear and cause pain.
AnkaraAges 18–65 - NCT07600359Recruiting
Physical therapy techniques for sacroiliac joint pain
This study compares two hands-on physical therapy techniques to reduce lower back pain, improve walking, and restore function in people with sacroiliac joint dysfunction (a condition affecting the joint connecting your spine to your pelvis). You'll receive treatment and be assessed to see which technique works better.
Islamabad, Punjab ProvinceAges 25–45 - NCT07602387Recruiting
Capsaicin cream for chemo-related nerve pain in legs
This study tests whether an 8% capsaicin cream (a chili-pepper derived treatment) can help reduce nerve pain and numbness in the legs caused by cancer chemotherapy drugs (taxanes). The cream is applied directly to affected areas, and the research team will track whether it improves your symptoms and pain levels over time.
Boulogne-Billancourt, HAUTS DE SEINEAges 18 years+ - NCT07599553Recruiting
Heart surgery with chest artery grafts: infection and pain study
This study follows patients undergoing bypass surgery where a artery from the chest wall (internal mammary artery) is used to reroute blood around blockages in the heart. Researchers will track infection rates, how well the graft stays open, and pain levels after surgery to understand how well this approach works.
Ottawa, OntarioAges 18 years+ - NCT07600229Recruiting
Barefoot Walking vs. Standard Care for Heel Pain
This study compares barefoot walking to standard conservative care (like stretching and supportive shoes) for plantar fasciitis—a common cause of heel pain. Researchers want to see if walking barefoot helps reduce pain and improve function in people with persistent heel discomfort.
Carlow, Carlow CountyAges 18–70 - NCT07595718Recruiting
Using health data and AI to predict major diseases
This study uses your health information and artificial intelligence to help predict the onset of major diseases. By joining, you could help improve early detection and prevention for conditions like diabetes, heart disease, and cancer.
Seoul, Seoul Special CityAges 30–65 - NCT07599254RecruitingPhase 4
Pain Relief After Root Canal Retreatment
This study tests two different ways of cleaning and treating a tooth that had a root canal treatment before. Researchers want to see which method causes less pain after the procedure.
KayseriAges 18–60
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Common questions
- Are there clinical trials for pain?
- Yes. Clin2 currently lists 3,142 recruiting pain studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a pain trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a pain trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.