Clinical trials
Pain clinical trials
Below are recruiting pain clinical trials, each written for real people, not researchers. We’re tracking 3,263 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07410780Recruiting
Pain after root canal with two different sealers
This trial compares two types of root canal filling materials—bioceramic and calcium hydroxide—to see which one causes less pain after the procedure. If you have a tooth with a live but inflamed nerve, you may be able to join.
Rawalpindi, Punjab ProvinceAges 18–40 - NCT07030582Recruiting
Online therapy for back pain and recovery after spinal fusion
This trial tests if internet-based cognitive behavioral therapy can help people recover better after lumbar fusion surgery by reducing pain, strengthening back muscles, and improving outlook on recovery. You can participate from home using WiFi.
Nantong, JiangsuAges 18–55 - NCT06807866RecruitingPhase 4
Duloxetine for pain after hip replacement surgery
This trial tests if duloxetine, a medication that helps with nerve pain, can reduce pain after hip replacement surgery. It may help patients who are having a first-time total hip replacement.
Miami, FloridaAges 18 years+ - NCT07409688RecruitingPhase 4
Pain relief after gallbladder surgery: comparing two ways to give local anesthetic
This trial compares two methods of giving local anesthetic during laparoscopic gallbladder removal to see which provides better pain relief. It may help patients recover with less pain after surgery.
Rawalpindi, Punjab ProvinceAges 15–60 - NCT06765486Recruiting
Exercise and pain relief: arm vs leg training
This trial compares how resistance training of the arms versus legs affects your body's natural ability to reduce pain. It may help understand which type of exercise is best for managing pain.
MadridAges 18–64 - NCT07703332Recruiting
Stretching methods for arm pain from overuse
This study tests two different stretching techniques to see which one better relieves arm pain and improves movement in people with overuse injuries. It may help you if you have long-lasting discomfort from repetitive activities like typing or manual work.
Faisalabad, Punjab ProvinceAges 20–50 - NCT06729437Recruiting
Transcranial brain stimulation for patellar tendon pain
This trial tests whether a gentle brain stimulation technique called transcranial direct current stimulation (tDCS) can improve knee function and reduce pain in people with long-term patellar tendinopathy (jumper's knee). It may help by calming pain signals in the brain.
Valencia, ValenciaAges 18–50 - NCT06080464Recruiting
Doctor satisfaction with VERABAND™ for chronic low back pain
This study tests how satisfied doctors are with a wearable device called VERABAND™ that monitors movement in people with chronic low back pain. If your pain limits your ability to move, you may be able to help researchers understand if this device is useful during your regular non-surgical treatment.
La Jolla, CaliforniaAges 18–85 - NCT07417839Recruiting
Toy nebulizer vs distraction cards for children's fear during breathing treatment
This study compares using a toy-shaped nebulizer or distraction cards to reduce fear in children aged 3-6 who are receiving their first breathing treatment for asthma or bronchitis. It aims to see which method makes the experience less scary and increases parent satisfaction.
Baghdad, MouslAges 3–6 - NCT07547215Recruiting
TRAQ Minimally Invasive Sacroiliac Joint Fusion Study
This study tests a minimally invasive surgical procedure called TRAQ to treat chronic sacroiliac joint (SIJ) pain—a type of lower back and buttock pain. The procedure may help if you've had pain for at least 6 months that didn't improve with non-surgical treatments and have already benefited from diagnostic joint injections.
Tucson, ArizonaAges 21 years+ - NCT06633068RecruitingPhase 2
Pain relief study: nalbuphine added to numbing medicine for thyroid surgery
This study tests if adding nalbuphine to the numbing medicine (bupivacaine) given as a nerve block before thyroid surgery provides better pain relief. It is for adults having planned thyroid surgery.
Giza, الجيزةAges 18–60 - NCT06534775Recruiting
Chronic pain after sternotomy follow-up study
This study checks if chronic pain after sternotomy changes over time. If you were in the original PABLOS study, you may be able to join this follow-up.
Angers, Maine Et LoireAges 18 years+ - NCT06527183Recruiting
Fibromyalgia and small fiber nerve study
This study looks at whether people with fibromyalgia or long-term chronic pain have damage to the small nerve fibers in their skin. Understanding this could help develop better treatments.
Boulogne-BillancourtAges 18 years+ - NCT06520631Recruiting
Cryotherapy for pain from dialysis needle insertion
This study tests if applying cold therapy (cryotherapy) to the access site before needle insertion can reduce pain during hemodialysis. If you are on dialysis and have an arteriovenous fistula, this might help make your treatment more comfortable.
CairoAges 30–50 - NCT06509087Recruiting
Combining CT and MRI for joint pain procedure
This study tests a procedure called transarterial microembolization for chronic shoulder or knee pain that hasn't improved with other treatments. It uses both CT and MRI to guide the procedure and see if it can help reduce pain.
TaipeiAges 20–80 - NCT06511401Recruiting
Pain treatment guided by your genes
This study looks at whether knowing your genetic makeup can help doctors choose the safest and most effective pain medicine for you before you start taking opioids. If you are being treated for cancer and may need opioid pain medication soon, this trial might be a fit.
Chicago, IllinoisAges 18 years+ - NCT07677540Recruiting
Nerve blocks before chest surgery to prevent long-term pain
This study is looking at two different types of nerve blocks—one called an erector spinae block and one called thoracic epidural—given before chest surgery to see if either can help prevent long-term pain after the operation.
Kfar SabaAges 18–99 - NCT06287515RecruitingPhase 1
Radiation to the pituitary gland for cancer pain
This study tests a focused radiation treatment on a small gland in the brain to see if it can relieve cancer-related pain that hasn't been controlled by standard treatments like painkillers or other therapies. It may help patients whose pain limits their daily life.
Houston, TexasAges 18 years+ - NCT06365892Recruiting
Open-label placebo for pain after scoliosis surgery
This trial tests whether taking a placebo pill that you know is a placebo (open-label placebo) can help reduce pain after spinal fusion surgery for scoliosis. It compares the placebo to standard care in adolescents aged 11-17.
San Francisco, CaliforniaAges 10–18 - NCT06348719Recruiting
Robot vs. standard laparoscopy for early endometrial cancer
This trial compares two types of minimally invasive surgery (robot-assisted vs. conventional laparoscopy) for removing the uterus in people with early-stage, low- to intermediate-risk endometrial cancer. The goal is to see which approach offers the best value and outcomes.
LilleAges 18 years+ - NCT06347991Recruiting
Chiropractic self-care app study for back pain in Alberta
This study tests an app called SelfBack that helps chiropractic patients manage their own long-term low back pain. You will use your smartphone to receive personalized exercises and tips. It may help you take control of your back pain between chiropractic visits.
Edmonton, AlbertaAges 18 years+ - NCT06660680Enrolling by invitationPhase 3
Methylene blue for pain after hemorrhoid surgery
This trial tests whether injecting methylene blue (a dye) into the area around the anus during hemorrhoid surgery can reduce pain after the operation. If you are having Milligan-Morgan surgery for mixed hemorrhoids, this study may help find a way to make your recovery more comfortable.
Hefei, AnhuiAges 18–75 - NCT07198919Enrolling by invitationPhase 1/Phase 2
Pain relief during root canal for infected tooth: gel vs. antibiotic paste
This trial compares two medicines placed inside a tooth after root canal cleaning to see which reduces pain better between appointments. If you have an infected single-root tooth and are between 16-45 years old, you may be able to join.
Karachi, SindhAges 16–45 - NCT06165991RecruitingPhase 4
Comparing two types of numbing medicine for lung surgery pain
This trial compares two forms of a numbing medicine (bupivacaine) injected near the spine to reduce pain after lung surgery. It aims to find which works better for controlling pain after a lobectomy (removal of a lung lobe).
Jinan, ShandongAges 18 years+
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Common questions
- Are there clinical trials for pain?
- Yes. Clin2 currently lists 3,263 recruiting pain studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a pain trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a pain trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.