Clinical trials
Pain clinical trials
Below are recruiting pain clinical trials, each written for real people, not researchers. We’re tracking 3,142 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07599254RecruitingPhase 4
Pain Relief After Root Canal Retreatment
This study tests two different ways of cleaning and treating a tooth that had a root canal treatment before. Researchers want to see which method causes less pain after the procedure.
KayseriAges 18–60 - NCT07590752RecruitingPhase 2/Phase 3
Pain Relief Comparison for Abdominal Surgery
This trial compares two medications added to a numbing injection around your abdominal muscles during belly surgery to help manage pain after surgery. The study aims to find which combination works better and lasts longer.
Sahiwal, Punjab ProvinceAges 25–65 - NCT05241197Recruiting
Low-load leg training with blood flow restriction for Achilles pain
This study tests whether gentle resistance exercises plus a blood-flow restriction wrap can reduce long-lasting Achilles tendon pain. You may be asked to train in the clinic several times a week for 12 weeks.
Rosario, Santa Fe ProvinceAges 18–50 - NCT07591584Recruiting
Digestive Enzyme Blend for Bloating and Gas Relief
This study tests whether a daily digestive enzyme supplement designed to break down certain hard-to-digest foods can reduce bloating and belly pain. You'll use a smartphone app to track your symptoms over several weeks to see if the enzyme helps.
Los Angeles, CaliforniaAges 18 years+ - NCT06067958RecruitingPhase 3
Nose spray medicine for pain during eye exams in preemies
This study tests a nose spray medicine (dexmedetomidine) to help reduce pain and discomfort in premature babies who need eye exams for retinopathy of prematurity (a condition that can affect vision). The goal is to see if the spray works better than the usual care for calming babies during the exam.
Be’er Ya‘aqov, CenterAges 4 weeks+ - NCT07591207Recruiting
Pain relief patch after laparoscopic abdominal surgery
This trial tests whether a pain-relief patch (loxoprofen) works well and safely to reduce pain after common laparoscopic surgeries like gallbladder, appendix, or hernia repair. If it works, it could offer patients a non-invasive way to manage post-surgery pain.
Beijing, Beijing MunicipalityAges 18–64 - NCT07590050Recruiting
Catgut Embedding for Lower Back Pain and Blood Stasis
This trial tests catgut embedding (a traditional acupuncture technique using absorbable material) to treat chronic lower back pain caused by spine wear-and-tear, particularly for patients whose condition matches a traditional medicine pattern called 'blood stasis.' The goal is to see if this approach relieves pain and improves movement.
Ho Chi Minh City, Ho Chi Minh CityAges 18–65 - NCT07588061Recruiting
Neck Pain Treatment: Mobilization and Posture Exercises
This study tests whether combining two types of physical therapy—manual joint mobilization and specific posture-strengthening exercises—can reduce neck and upper back pain and improve how you hold your body. You may qualify if you have persistent neck pain linked to poor posture.
Peshawar, KPKAges 18–45 - NCT07588087Recruiting
Shoulder Release Therapy for Frozen Shoulder Pain
This study tests whether adding a specific muscle-release technique to shoulder exercises helps reduce pain and improve movement in frozen shoulder (adhesive capsulitis). Frozen shoulder causes stiffness and pain that limits arm movement; this trial explores whether combining two physical therapy methods works better than standard care.
Islamabad, Punjab ProvinceAges 35–70 - NCT07588230Recruiting
Nerve Block for Minimally Invasive Heart Valve Surgery Pain
This study tests a targeted nerve block (pain-numbing injection) to help manage pain after minimally invasive heart valve surgery. Researchers want to see if this technique reduces pain and the need for opioid medications during recovery.
Diyarbakır, Outside of the USAges 18–75 - NCT07588165Recruiting
Measuring Pain During Emergency Breathing Tube Placement
This study tests a pain-monitoring device during emergency anesthesia for stomach or abdominal surgery. Researchers want to see how well the device (called ANI) detects pain when doctors quickly put a breathing tube in your airway.
MonacoAges 18 years+ - NCT07590323Recruiting
Blood Flow Restriction Training for Knee Osteoarthritis
This study tests whether a special training method called blood flow restriction (BFR)—which uses a cuff to safely limit blood flow while you exercise—can help reduce knee osteoarthritis pain and improve function. You'll do supervised exercises three times a week for 8 weeks.
Ha'il, Ha'il RegionAges 40–70 - NCT07591324Recruiting
3D-Printed vs. Traditional Space Holders for Kids' Teeth
This study compares two types of dental devices that hold space in a child's mouth after baby molars fall out early. The research tests whether a newer 3D-printed version works as well as or better than the traditional wire-based device.
Ismailia, Ismailia GovernorateAges 7–9 - NCT07591233Recruiting
Pain Relief Injection During Laparoscopic Surgery
This trial tests whether injecting a numbing medication mixed with a steroid into the surgical area before making cuts can reduce pain after common laparoscopic procedures like gallbladder removal or hernia repair. The goal is to help patients recover with less pain and fewer pain medications.
Beijing, Beijing MunicipalityAges 18–64 - NCT07594041Recruiting
Videos for heart care education in children
This study tests whether short educational videos help caregivers of children with heart conditions understand their child's diagnosis and care plan better than standard spoken information alone.
San Antonio, TexasAges Up to 18 years - NCT07590895Recruiting
Low-FODMAP Diet for Endometriosis Pain and Bowel Symptoms
This study tests whether a low-FODMAP diet (a way of eating that limits certain hard-to-digest foods) can reduce pelvic pain, improve quality of life, and help bowel symptoms in women with endometriosis. Endometriosis is a condition where tissue similar to the uterine lining grows outside the uterus, often causing pain and digestive problems.
MilanAges 18–45 - NCT07587931Recruiting
Concentric vs Eccentric Exercise for Partial Rotator Cuff Tears
This study compares two types of shoulder exercises—one where you shorten the muscle and one where you lengthen it—to see which works better for partial tears of your rotator cuff (the muscles that stabilize your shoulder). The goal is to reduce pain and improve shoulder function.
Elâzığ, MErkezAges 18–65 - NCT06246669Recruiting
Exercise and fear after concussion in college athletes
This study looks at whether prescribed exercise can help college athletes feel less afraid of pain after a concussion. It aims to see if exercise helps them recover better.
Charlottesville, VirginiaAges 18–25 - NCT07577869Recruiting
Nerve blocks for pain relief after knee replacement
This trial tests two types of numbing injections (nerve blocks) around the knee to help manage pain after total knee replacement surgery. The goal is to see if these injections reduce pain and improve recovery compared to standard pain treatment.
Kayseri, KocasinanAges 18–80 - NCT07579312Recruiting
Blood Test for Diagnosing Belly Infections in Kids and Adults
This study tests whether a simple blood test measuring RNA levels can help doctors quickly identify intra-abdominal infections (infections inside the belly) in patients with abdominal pain. If successful, it could help doctors decide faster whether imaging or surgery is needed.
Washington D.C., District of ColumbiaAges 7 years+ - NCT07578324Recruiting
TENS to reduce pain during prostate biopsy
This study tests whether TENS (a gentle electrical stimulation applied to the skin) can help reduce pain when combined with numbing medicine during a prostate biopsy procedure. The goal is to see if this may make the biopsy more comfortable for patients.
Gdansk, Pomeranian VoivodeshipAges 40 years+ - NCT07585721Recruiting
Pain Relief After Root Canal Treatment: Two Different Medications
This study compares two types of medications placed inside a tooth after root canal treatment to see which one reduces pain better. You'll be asked about your pain levels after treatment, and researchers will measure a pain-related substance in your saliva.
CairoAges 18–45 - NCT07577934Recruiting
Liposomal Bupivacaine for Pain Relief in Gallbladder Surgery
This trial tests a long-acting numbing medication (liposomal bupivacaine) injected around abdominal muscles during laparoscopic gallbladder removal to reduce pain after surgery. The goal is to see if it provides better pain control compared to standard approaches.
Tianjin, Tianjin MunicipalityAges 18–65 - NCT07580157Enrolling by invitation
Shockwave therapy for knee pain after ACL surgery
This study tests whether focused shockwave treatment can reduce knee pain in people who have had ACL (anterior cruciate ligament) reconstruction surgery. Shockwave therapy uses sound waves to reduce pain and inflammation.
Rochester, MinnesotaAges 18 years+
Hear when a new Pain trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for pain?
- Yes. Clin2 currently lists 3,142 recruiting pain studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a pain trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a pain trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.