Clinical trials
Painful Diabetic Neuropathy clinical trials
Below are recruiting painful diabetic neuropathy clinical trials, each written for real people, not researchers. We’re tracking 65 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07195045Recruiting
Thai PainPREDICT validation study for diabetes nerve pain
This study tests a tool (PainPREDICT) to predict nerve pain in people with diabetes. It aims to identify those at risk so treatment can start early.
Pathum Wan, BangkokAges 18 years+ - NCT07210203Recruiting
Nerve gliding for pain, balance, and quality of life in diabetic nerve damage
This study tests whether adding nerve gliding exercises (neural mobilization) to usual care can reduce pain, improve balance, and enhance quality of life for people with diabetic peripheral neuropathy. It may help if you have mild to moderate nerve pain and are between 50 and 75 years old.
IslamabadAges 50–75 - NCT07260656RecruitingEarly Phase 1
Capsaicin cream for diabetic nerve foot pain
This trial tests a new cream (Capsadyn®) made from chili pepper extract to see if it can reduce nerve pain in the feet caused by diabetes. If it works, it could offer a simple treatment you apply at home.
Roanoke, VirginiaAges 25–75 - NCT07298408RecruitingPhase 1/Phase 2
CBD for Diabetic Nerve Pain: A Pilot Study
This trial tests whether a daily dose of CBD (a cannabis compound) can help reduce nerve pain from type 2 diabetes. It's a small, early study to see if it's safe and effective.
Tallahassee, FloridaAges 40–70 - NCT07509671Recruiting
Can a diet help painful diabetic nerve pain?
This study tests whether a special diet can help reduce pain caused by nerve damage from Type 2 diabetes or prediabetes. You may qualify if you have painful diabetic neuropathy and are looking for a non-medication approach.
Hendersonville, North CarolinaAges 18 years+ - NCT07250828Enrolling by invitation
BurstDR spinal cord stimulation for painful diabetic neuropathy
This trial tests a type of spinal cord stimulation called BurstDR to see if it can reduce pain from diabetic nerve damage. It may help people with diabetes who have ongoing leg pain that hasn't gotten better with standard pain medications.
Grand Island, NebraskaAges 19 years+ - NCT07141992Enrolling by invitation
Nerve glide exercises for burning pain from diabetic neuropathy
This study compares two types of nerve gliding exercises to see which works better for reducing burning pain, improving muscle strength, and increasing movement in patients with diabetes-related nerve damage.
Karachi, SindhAges 40–65 - NCT07126197Enrolling by invitation
Lymphovenous bypass for diabetic nerve pain
This study tests if a surgery called lymphovenous bypass can reduce nerve pain caused by diabetes. It may help people with diabetic peripheral neuropathy, even if they have foot ulcers.
TaipeiAges 20–80 - NCT07625020Recruiting
Nerve Hydrodissection for Diabetic Nerve Entrapment Pain
This trial tests a minimally invasive ultrasound-guided procedure that uses fluid injection to free trapped nerves in the lower legs of people with diabetes. The goal is to relieve pain, numbness, and weakness when standard medications haven't worked well enough.
Chongqing, Chongqing MunicipalityAges 18–85 - NCT07625007Recruiting
Shortwave Therapy for Diabetic Nerve Pain
This trial tests a shortwave treatment to relieve pain and other nerve symptoms in people with diabetic peripheral neuropathy (nerve damage from diabetes). It is for adults who have not found enough relief from standard nerve medications.
ChongqingAges 18–85 - NCT07708233RecruitingPhase 4
Benfotiamine vs vitamin B complex for diabetic nerve pain
This study compares two types of vitamin B supplements to see which one better relieves nerve pain and numbness in people with diabetes. It may help if you have diabetic neuropathy and are looking for a safe, non-drug option.
Pathumthani, BangkokAges 18 years+ - NCT07183761RecruitingPhase 2
Stem cell therapy for diabetic nerve pain
This study tests whether umbilical cord stem cells can help people with diabetic nerve damage in their legs who haven't gotten enough relief from standard treatments. It aims to improve symptoms like numbness, pain, and tingling.
Chongqing, Chongqing MunicipalityAges 18–80 - NCT07028528RecruitingPhase 2
Study of Levagen+ for diabetic nerve pain
This trial tests if Levagen+ (a supplement) can reduce nerve pain caused by diabetes. It is for people with type 1 or type 2 diabetes who have significant nerve pain in their feet or legs.
Fortitude Valley, QueenslandAges 18–75 - NCT05965336Recruiting
Walking test study for nerve damage in diabetes feet
This study looks at how well people with diabetes-related nerve damage (diabetic peripheral neuropathy) can walk, using a treadmill and walking distance tests. It may help improve understanding of walking limits and how to measure change over time.
Pensacola, FloridaAges 45 years+ - NCT07285018RecruitingPhase 2
Study of a new drug for diabetic nerve pain in legs
This trial tests an investigational drug for people with pain caused by nerve damage from diabetes (diabetic peripheral neuropathy). It may help reduce pain in your lower legs if other treatments haven't worked well.
Birmingham, AlabamaAges 18 years+ - NCT06155487Enrolling by invitationPhase 1
AJH-2947 safety study in healthy men
This trial tests the safety of a new oral drug, AJH-2947, in healthy Korean or Caucasian men. It helps determine how the body processes the drug and if it causes any side effects.
SeoulAges 19–55 - NCT06124586Recruiting
Early angioplasty for diabetic foot ulcers
This trial tests if an early procedure to open blocked leg arteries (angioplasty) helps heal foot ulcers in people with type 2 diabetes. It aims to improve blood flow and prevent amputation.
DüsseldorfAges 18 years+ - NCT07451431RecruitingPhase 4
Mirogabalin for diabetic nerve pain study
This study tests a new pain medicine called Mirogabalin for people with diabetic nerve pain that hasn't gotten better with usual treatments. It aims to see how well the drug works and if it is safe.
DhakaAges 40 years+ - NCT07377721RecruitingPhase 1
Study of HRS-2129 for diabetic nerve pain
This trial tests a new medicine called HRS-2129 for people with long-term nerve pain caused by diabetes. It aims to see if the drug can safely reduce pain.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06912646Recruiting
Laser therapy for foot pain from idiopathic neuropathy
This trial tests a laser device for temporary relief of foot pain from peripheral neuropathy when the cause is unknown. It may help if you have constant foot pain and are not diabetic.
Miramar, FloridaAges 22 years+ - NCT04658693Recruiting
Restore leg sensation in diabetic nerve damage with safe stimulation
This study tests a treatment that delivers mild stimulation to help bring back lower-limb feeling in people with diabetic nerve damage (or an insensate foot) and may also protect nerves. If you qualify and can safely take part in testing and follow-up, it could improve sensation and walking comfort.
Cleveland, OhioAges 18 years+ - NCT06880484Enrolling by invitation
Far-infrared socks for diabetic nerve pain
This study tests whether special far-infrared socks can help relieve nerve pain and improve nerve function in people with diabetic nerve damage. If you have mild to moderate nerve pain and live in Kayseri, you may be able to join.
Talas, KayseriAges 19 years+ - NCT07301177Recruiting
Magnetic stimulation for veterans with nerve pain after injury
This study tests whether a non-invasive magnetic stimulation treatment can help veterans with long-term nerve pain after an injury or surgery. It may offer a drug-free option to reduce pain and improve quality of life.
San Diego, CaliforniaAges 18 years+ - NCT04299893RecruitingPhase 2/Phase 3
Ozone treatment for chemotherapy nerve pain
This trial tests whether ozone therapy can reduce painful nerve damage caused by chemotherapy. It is for adults with ongoing moderate-to-severe pain in the hands or feet after chemotherapy.
Las Palmas de Gran Canaria, Las PalmasAges 18–100
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Common questions
- Are there clinical trials for painful diabetic neuropathy?
- Yes. Clin2 currently lists 65 recruiting painful diabetic neuropathy studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a painful diabetic neuropathy trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a painful diabetic neuropathy trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.